What Is Methylation + How To Support It | Dr. Will Cole
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- čas přidán 20. 05. 2024
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Topics Covered:
How methylation effects our body.
What is the importance of methylation?
What supplements can help support methylation
This episode was sponsored by LivOn Lab www.livonlabs.com/willcole/
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#podcast #liveonlabs #drwillcole
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ABOUT DR. WILL COLE Dr. Will Cole is a leading functional medicine expert who consults people around the globe via one of the first functional medicine telehealth centers in the world. Named one of the top 50 functional and integrative doctors in the nation, Dr. Will Cole specializes in clinically investigating underlying factors of chronic disease and customizing a functional medicine approach for thyroid issues, autoimmune conditions, hormonal imbalances, digestive disorders, and brain problems. He is also the host of the popular The Art Of Being Well podcast and the author of Ketotarian, The Inflammation Spectrum, and the New York Times bestseller Intuitive Fasting.
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Functional medicine for everyday people around the world.
Just wondering if exposure to EMF pollution can interfere with the methylation cycle and or nutrient absorption and or gut health in general?
with regards to the Livon labs product.. the b12 is only 50 mcg. a typical conservative daily dosage is 1000 mcg.. some supplements do 1mg. and it includes cyanocobalamin. not good. It doesn't say what the riboflavin is. so it's probably not FMN or riboflavin 5 phospate - the 2 active forms. It's probably just free B2. thought this was an active b complex. But then the B6 should be P5P. the phosphorylated or active.form. please check what Pyridoxine hci is. just like thiamine hci. not good.
Check out Thorne supplements. They use the correct versions of B vitamins. Even methylated version of b12
Basic question: Is this methylation talking about DNA methylation (turning gene expression on/off) or something else?
Great video & information (Note: background noise distracting)
Thanks Dave J
I'm an under methylator with higher blood histamine. Your recommendation? I do poorly with B vitamins and have high folate in the blood as well, which I attribute to synthetic dietary folate consumption.
So to be clear (because the internet is obsessed with MTHR), methylation concerns everyone including those without the MTHR gene who may have other less optimal methylation genes? In short, is it safe to say that everybody has methylation strengths and weaknesses genetically, and so everyone needs their diet tailored to their genetics?
The livon labs link for the b complex does not work. It says connection not secure.
Excellent
But I use Bio- Active B- Complex supplements from Canadian company CanPrev ....I love it
All the B's are in methylated group or methylated form
I agree 👍 100% with you regarding b- Vitamin the most difficult supplement to get from good source and lab not Petroleum base 😉
Doc.
Can you please do a video on Sulfation or *SA Me * supplement please and how it work who needs to take it
Hello mate I had gall bladder removed a decade ago and have not been able to shift weight off unless my diet is super clean which is too hard, 103 kilos at 6/1 height and train every day, I have been taking a methylated vitamin B and have lost 7 kilos in 2 weeks without trying, I’m 51 any ideas what’s going on as I do feel better and sleeping better, cheers mate
Do you have any info on reactive hypoglycemia? I felt really unwell eating meals with meat. I have the MTR mutation homozygous C6 717 I recently tried a 30 day grape fast and I felt totally wonderful. Lots of my symptoms, including acathisia went away. I was damaged by medication, it seems though when I try to add protein back into my diet such as a piece of fish, I get really bad symptoms of filling, drunk tired spaced out sleepy just I do not feel good then I want to eat sugar after it
I to have homozygous mthfr c677t mutation. I to am incredibly sensitive to protein. I get migraines, worsening of depression, anxiety, insomnia. But mainly I get instant migraines. If I drink protein shakes, a lot of meat in one sitting, foods with msg, or aspartame. I no doubt have a issue with glutamate because in my opinion because of my reduced mthfr function my brain cannot produce enough serotonin, dopamine, norepinephrine to create a balance. But I'm always tired. Feel like crap. Have had lifelong depression, anxiety, insomnia, ocd.
your website includes a 'Become A Patient' button. I'm not sure how clicking on it can turn someone into a patient, but I didn't click, as a measure of precaution, anyway.
I think you misspelled methyl in your main title for this video.
but why didnt you mention things like choline or creatine?
What happens with creatin?
@@christian.mar.garcia About 45% of methyl groups created in the body from methylation is used for the synthesis of creatine. If you supplement with creatine, your body does not need to synthesis its own creatine, freeing up methyl groups for other purposes. Supplementing with creatine is one way to improve one's methylation status by reducing demand for the methyl groups.
Seriously, if he said everything there is to say about methylation, this video would be 2 hours long. Chris Masterjohn goes into detail in his lecture with Hawthorne University. You can look it up.
Choline and betaine are a less expensive way of methylation
Betaine HCL?
@@christian.mar.garcia betaine tmg
@@christian.mar.garcia TMG Trimethyl Glycine. Methyl donor. Effective to reduce Homocysteine.
@@christian.mar.garcia Not HCL. Just betaine (tri metyl glycine, TMG)