Tips for Living with MTHFR (and what to AVOID)
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- čas přidán 11. 04. 2024
- How to manage life living with MTHFR variations and what important things to AVOID. From my recent podcast with Karalynne Call @just.ingredients.podcast
Avoid these, or limit them, if having the MTHFR mutation or a dirty MTHFR gene:
- folic acid
- laughing gas
- methotrexate
Enjoy these if having the MTHFR mutation or a dirty MTHFR gene:
- real folate found in leafy green vegetables and liver
- L-methylfolate
- Folinic acid
- things which calm you down (instead of laughing gas) like CBD, calming herbs like passion flower or lemon balm or valerian or chamomile or wild oats
Dive deeper into MTHFR and 6 other really important genes with Dr. Lynch's book, Dirty Genes:
amzn.to/3TQh1yI
StrateGene Report:
Interpret over 100 genetic variations over 9 different pathways using your 23andme, Ancestry or SelfDecode raw data
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SHEI Membership: Monthly live calls with Dr. Lynch along with 100+ hours of Dr. Lynch’s conferences on genetics and epigenetics
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@DrBenLynch - Věda a technologie
I'm SO glad to see you back teaching. I'm 66 years old. Stratagene absolutely explained my whole family. And...saved my life! Thank you!
When I was 19, I was given nitrous oxide to remove my wisdom teeth. At 36 I got an Epstein Barr virus and later diagnosed with Lupus and given Methotrexate. It wrecked my life and relationships because people thought I was just being lazy. I didn’t find out till 2 years ago that I had MTHFR. It feels nice to be validated, so thank you.
Yes, I've had to grapple with these same feelings. I was especially harsh on myself about having chronic fatigue. I thought other people just handled life better or I was lazy. But eventually I realized, no, THIS kind of fatigue is not normal. I didn't take a nap every day for fun; I hated it. And chronic pain. Standing at the counter chopping veggies shouldn't be painful. But it was my normal for so long, I didn't realize how bad it was. When I realized, I was finally able to give myself some grace and begin healing. Turns out I was autistic all this time too. I really DID get a harder lot than others, but for some reason people don't like to think that others may actually have it harder than them. So they're a jerk and call you lazy instead. It's some sort of personal insecurity.
You're not alone ♡
I'm sorry you went through that awful experience and gaslighting. I have MTHFR also and I understand how fatigued you can be without supplementation and the right diet. Hugs!
I have mthfr double homozygous .
I found out after I had 2 brain strokes and they couldnt figure out why.
I was so sick, I developed an auto immune disease and was so so sick I could not walk.
5 years later at 54... I changed my diet..no dairy, no gluten and started suppliments full complex bs, d3 omegas & mthf ... I am now hiking in the woods again and exploring beautiful places. It was a life changer for me !! Im proof you can change your health with epigenetics :) ❤
awesome :)
This is so encouraging! You've done such an amazing job getting your health back on track! You should be proud of yourself ☺
It definitely seems like there are 2 extremes... Doctors who think it's useless and people online who attribute EVERY issue they've ever had with it. I appreciate your reasonable teaching on it.
great point.
OMG this is huge 😮I don’t have enough words to thank you for this dr Lynch, thank you very very much 🙏🙏🙏
Lots of mental health issues are being linked to diet - low carb/keto type diets seem to have very good results with treating mental health, including adhd.
They don’t like you doctor but WE LIKE YOU :). God bless you ❤
Thank you dr Lynch. Just bought your book & test kit - need your help dissecting this!!
So glad to have found you. I just ordered both Dirty Genes and The Histamine Workbook. Thank you so much for helping those of us who are just everyday people be able to take action and manage our health.
Thanks for your HELP‼️
Two of my children have had Stephen's Johnsons reactions to Penicillin. Could this be because of this variant? I have MTHFR from both of my parents. Laughing gas made me vomit almost immediately when I was a child. Do we know of any connection between cartilage issues?
Your guidance and support has been invaluable 🙌🏼 I'm forever grateful! Thanks a million! 😌
You're so welcome!
I very much enjoy the vignettes for my longterm memory!
🎯 Key Takeaways for quick navigation:
00:40 *🧬 Having the MTHFR variant doesn't guarantee specific health conditions but makes you more vulnerable due to reduced methyl folate production.*
01:39 *💡 Supplementing with methylfolate, dietary changes, and avoiding substances like folic acid can support MTHFR enzyme function.*
03:28 *🚫 Some medical organizations discredit testing for MTHFR, but awareness of vulnerability allows for proactive measures.*
05:31 *⚠️ Individuals with MTHFR variants should avoid medications like methotrexate and laughing gas due to potential adverse effects on B12 and folate.*
07:34 *🌟 Knowing your MTHFR status enables better health choices and awareness of potential risks and interventions.*
Made with HARPA AI
brilliant ;)
Should we take vitamin b12 with methylfolate? I'm trying to help my daughter. I just ordered vitamin b12 and methylfolate but I'm not sure if the b12 is the correct vitamin to take with it?
I was given laughing gas at the dentist when I was much younger. I just remember immediately feeling trapped inside my body and paralyzed. I had no control over my body. I told them to immediately stop and turn it off!! I never knew it could be related to MTHFR!! I thought I just couldn't mentally handle it.
WOAH, I panicked when given laughing gas as a kid!! I thought I was just too anxious and my fight-or-flight was activated when my brain recognized my reasoning capacity wasn't all there.... But I attacked the doctor and actually have no memory of it, which is totally uncharacteristic!! I've never blacked out from anything, heavy drinking, even anaesthesia I woke up totally conscious and remember things from that moment. But that is the ONE time that someone else had to tell me what actually happened.
@@Ayverie4 I think we saved our own lives! I’m almost 49 figuring this out.
Dr Ben I am having anxiety really bad. I refuse to take meds but need help. Any supplements in Seeking Health store I can buy?
he probably will never answer here... 95$ he wants, at least...
There could be variable reasons for a person experiencing anxiety. Giving an answer without knowing a persons history could prove deleterious and ineffective.
Till you figure out. ..I get relief from L THEANINE. AND AT NIGHT MAGNESIUM CALM.
ALSO TRY LEMON BALM.
❤
@@suzihazlove4979 thank you
Look up SAMe and try to get a quality one that doesn’t have fillers or flow agents.
I appreciate Dr. Lynch’s simple explanation. I have also listed to Dr. William Walsh who authored “Nutrient Power”, he goes into great detail with Methylation, along with epidemics, Copper overload, zinc, etc. Dr. Walsh has protocol which he has trained over 1000 psychiatrists around the world. He has over 1 million blood samples from psychiatric patients. Give him a listen- he goes really deep, with 30 years experience in this 🙏👍
Having a few previous surgeries I always vomited after anesthesia for couple of days afterwards.
I have Dirty Genes and I found out so many things about the MTHFR double mutation which I am ", blessed" to have.
I may have commented on this before, but do not the Methylated B Complex work well?
Any thoughts on Dr.Jack Kruse?
familiar but I don't follow his work. I agree with anyone who talks about the importance of the fundamentals of health - but in a healthful, non exaggerated manner.
I have double C677T variant. Would you say that proper supplementation and a balanced diet and lifestyle would bring the reduced function to 100%? Thank you. I appreciate you 😊
I'd phrase that differently. You cannot bring a frayed rope to 100% function. You can use it -but you have to be mindful. If you have 30% function of your MTHFR enzyme, and you do genetically, then with the right lifestyle and food, and periodic supplementation, you're absolutely fine. You can feel 100% with a 30% functional MTHFR enzyme. That's a more accurate way to put it. Check your homocysteine levels. You want them between 6 umol/L to 8 umol/L. Use Homocysteine Nutrients if above 8 umol/L or a multivitamin with methylated folate and B12. www.seekinghealth.com/products/homocysteine-nutrients
@@DrBenLynch Thank you so much. That makes a lot of sense. 😊
It gets confusing! Idiopathic PE led to finding out I have homozygous c677T, hyperhomocysteinemia, antiphospholipid. Dirty Genes says for mthfr to eat red meat, eggs, etc.….while sources for the hyperhomocysteinemia diet say no red meat, eggs, etc. These types of dualities keep me confused so I just eat what I feel like my body is wanting and support with supplements if I feel crappy. I am grateful for your supplements and for your teaching!
If one has high homocysteine, the solution is not to stop eating meat. It's to identify how much protein you are eating - and to support methylation. It's not all or nothing. It's a balancing act.
What are the interventions you can do if you have to have surgery and they use Nitric Oxide and you have MTFHR?
I may have RA and am dreading being asked to go on methotrexate. I am already low B12 and homozygous for A1298C. Really nervous to start taking meds 😢. I’m also allergic to cobalt so it’s very hard for me to get my levels up. So annoying.
Ask your doctors for a Biologic Medicine, that’s should really help your RA, aside from changing your diet.
@@carlavegas887 thank you. I have heard that usually insurance makes you “fail” other meds first (like methotrexate) before letting you start on a biologic(?)
find a doctor to put you on low dose naltrexone. get off all gluten and all cow dairy products. i'd also get on Histamine Digest and take with meals and before bed along with ProBiota HistaminX after dinner. www.seekinghealth.com/collections/histamine-intolerance-supplements
I have both genes the 677 and 1298. I found out in 2015 or so. I also had epstein barr and a whole host of problems. I have no idea how to treat it.
Hmm so what should I do when having MRTHR gene and taking Methotrexate for RA? So far i have replaced the folic acid they want me to take with it with methylfolate. Anything else needed?
I have the same. It's a bad situation in which to be. If your reumatologist is not willing to change your medication, take supplements to support methylation. I personally take active forms of B2, B6, B9, B12, Creatine (cuts methylation requirments in half, as per Dr Lynch), and Magnesium and/or other similar important co-factors. Just be mindful to not take too much, as some of this can give toxicity (B6 if in excess). So blood work also important to monitor. Also for RA, check your Vitamin D status, in general. And suggest you to bring to 60 at least, if lower than that. The 25-H form. Hope this can help.
What is best for someone who is vegan and has MTHFR mutation?
you advise to use 7.5 mg or more of 5-mthf ?
oof - way way less. Start out low and go from there - and ideally use MTHF with Methyl B12 so it works more effectively - www.seekinghealth.com/products/methyl-b12-with-l-methylfolate - start with 1/4 to 1/2 lozenge - this is 800 mcg of MTHF - and it's powerful - start low so you don't regret it.
So if we have MTHFR some version, we cannot take nitrous oxide for pain relief during minor surgeries??? Or what happens?
you should not use nitrous oxide no. You should use CBD or some other thing that reduces your anxiety levels. Nitrous oxide is NOT pain relief. It is designed to reduce anxiety mainly with a minor pain relief component
@@DrBenLynch I dont have anxiety but laughing gas eliminates pain for dental or cosmetic skin procedures. Never had any bad reaction to it and have used it couple times a year for at least 5 years. Am I misunderstanding your comment?
Is there a list of Ben Lynch approved consultants who can analyse my info and just give me the actionable steps? (I know the strategene report is good for the proactive people, but I’m still too dumb and lazy to know what to do, I just want someone to spoon feed me). Thank you.
you're not dumb :) - you're unfamiliar with biochemistry and genetics. It's new territory. You could absolutely learn it if you had the time and ability to dedicate effort to it. Life's busy. Reach out to my team at seekinghealth.com for a list of health professionals.
@@DrBenLynch Thanks, Sir. I will do that. Have a good day.
I would like to add, that when taking B complex plus folate, in the afternoon I would get so tire that I had to take a 15 minute nap, and then I would be excellent......then I was told that it is best to take vitamin B complex at the night..............game changer for me...............any opinions? Also the folate had me irritated a lot of times!!!! some of the pills had to much........i don't take it as often and I fell much better...........has this happen to you, that folate would make you anger, and anxious, short temper, etc?
Everyone is different. Usually I recommend a full spectrum B complex to be taken during the day never at night. Folate definitely can increase irritation, headaches and other issues. I often do not take, or recommend others, to take, the full suggested serving size of any of our multivitamins at seekinghealth.com if they are sensitive. We also have a line for people who are sensitive to methylfolate. This line is called 'MF' which stands for Methyl-Free. We have a Prenatal Essentials MF, Multivitamin One MF, Kids Chewable Multivitamin MF for example. All using folinic acid and hydroxocobalamin instead of the stimulating methylcobalamin and methylfolate.
@@DrBenLynch Thank you for your response, I guess I'm one of those LOL, sensitive to Folate
I guess this is why l-citrulline gave me insomnia.
What if the reason we have this variant is epigenetic... the consequence of a century of ubiquitous lead poisoning, for instance?
it is epigenetic at this point - it's easier to be born with MTHFR now that we have so much pregnancy intervention -
👏👏
Is there a place to go to explain the different snips/variants? I know I have MTHFR 1298 AC? I have Ace DD. I have COMT val158met GG. I have MAOA arg297arg TT. NOS -786 TT. DAO his645 CG. GSTM1 DEL. But I dont know if these are the ones with issues. I did 3x4 and gives some detail but wondering if there is a better place to research. Thanks in advance
Folinic acid, I read somewhere better avoid this one also
yeah - you probably did read that somewhere. The internet is FULL of inaccurate information. Folinic acid is great.
Folinic Acid has been crucial in my severe concussion recovery and beating POTS postural orthostatic tachycardia syndrome. I will need to take it for the rest of my life. It has helped me get a second chance at life. I have the MTHFR gene variant which I was tested for after my brain injury. I do not tolerate methyl folate, methyl trapping.
Got my StrateGene Results yesterday. Relieved that I only have two very important Folate Cycle SNPs. Reduced Methylfolate/B12. Many other cycles far more compromised. I’ll ask your team for a consulting doctor referral. So profoundly grateful for your brilliant work❣️
One curious personal question: Have you taken Dr d’Adamo’s Geno Type testing and are you an Explorer Geno Type? I’m an Explorer Geno Type, that’s why I ask.
Folate Cycle SNPs
MTHFR A1298C +/+ GG
SLC19A1 G80A +/+, TT
I haven't taken Peter's test. That's interesting. What combination of SNPs makes one an explorer genotype? There research on that?
Dr Lynch, what a delight!
I took the test many years ago. Since then I’m aware how identified I am with my genotype. As I recall, he measures mostly physical features. Like you, Peter is brilliant. I first read his work in a journal called the Townsend Letter back in the mid 90s. It matched so closely with my own health changes that I’ve had unwavering confidence in his work ever since. I suggest that you order the test to see what genotype you are. As I recall there are currently six types. The topic is fascinating!