Shocking Truth: High B12 Linked to Cancer. Quantified B12 Levels, Cancer Types, MCAS, Mastocytosis
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- čas přidán 15. 07. 2024
- Do you have ongoing elevations in your vitamin B12 level? Maybe you're having a lot of concern about whether or not you might have cancer or some other bone marrow problem? In this video, we're going to go into some of those risks, specifically going to look at what are the most common types of cancer that are associated with elevated B12.
**My Book: Don't B12 Deficient geni.us/rTQTvd (amazon link) **
Reference: academic.oup.com/qjmed/articl...
Some of the testing and strategies you might want to consider when you have this going on, as well as some ways to look at it and understand what's going on in your body when you have ongoing elevated B12 levels
Do you have ongoing elevations in your vitamin B12 level? Maybe you're having a lot of concern about whether or not you might have cancer or some other bone marrow problem?We're going to go into some of those risks, specifically going to look at what are the most common types of cancer that are associated with elevated B12.
Some of the testing and strategies you might want to consider when you have this going on, as well as some ways to look at it and understand what's going on in your body when you have ongoing elevated B12 levels. High B12 on a blood test is not something that most people should or need to worry about. As I've said in previous videos, most of the time it's occurring because you're taking a B12 supplement in some shape or form. Maybe it's a multivitamin or it could be a vitamin drink or energy drink with B12 in it.
The problem is what happens when that's not the case? What happens, for instance, when you haven't taken any B12 in years, either in the form of injection or oral or even vitamin drinks?
That's when you want to make sure you don't have something more serious going on like cancer. And that's what I'm dedicating this video to discussing. Sort of the worst-case scenario type things.
Now, I hesitate to make a video like this because in the vast majority of people, it's high for some benign reason. And a video like this may create unnecessary fear. Still, I think the opposite perspective can also be used. What if it helps someone get a diagnosis earlier?
So with that, let me share some finer points about this topic. Let me first quickly start by mentioning the benign reasons for high B12, and they are, you're either taking vitamin B12, there's some genetic reason that you have elevated B12, either with the transcobalamin molecules or other genetic aspects, and then some not so benign reasons like problems with your liver, kidney, or even solid tumors in these organs.
It's usually pretty straightforward to get your kidney and liver checked and to check to make sure you're not taking B12. After this though, what is the next step? What are you going to do?
Well, it really depends on how long it's been high for and how high it actually is. Each case would have to be looked at on an individual basis. So here I'm attempting to give you a little more context on this topic so you can decide along with your healthcare provider when it's time to dig a little bit deeper and see, for instance, a hematologist.
In the last video on high B12 or elevated B12, we discussed that B12 is carried throughout our bodies via three carrier proteins known as transcobalamins. They're made in the liver and they can also be made in white blood cells called granulocytes. These types of white blood cells increase in conditions like mast cell activation syndrome, mastocytosis, and white blood cell cancers.
In all these cases, it can lead to more of the proteins that bind B12 or transcobalamins, less of the B12 getting into the cell, and more floating around in your blood, thus spiking the test. So if you have ongoing high levels of B12, what are you actually going to do? The first thing is to consider just scheduling with the hematologist. They will do and know more than you're gonna get from a video like this. You can also get a test done which was mentioned in the previous video video on Unsaturated B12 binding capacity.
As mentioned in the previous video, if this is elevated outside of the lab's reference range and you also have high serum B12, it suggests an increased production of those binding proteins, those transcobalamins. In this case, your body may be making more of those granulocyte type of white blood cells. That doesn't necessarily mean it's cancer, but it also does increase the chances that it is. But things like mast cell activation, mast cell activation syndrome, and other similar disorders can also do this. Polycythemia vera, hyper eosinophilic syndrome, and cancers like chronic myeloid leukemia, primary myelofibrosis, myelodysplastic syndromes, and acute leukemias are all well-documented reasons for having elevated B12. - Věda a technologie
Very interesting! thanks
Glad you liked it!
Many Thanks Doc; as an experienced practitioner myself, I appreciate the quality of the information that you provide. It's clearly well researched and integrated, and explained in ways that make sense to most people! Much appreciated!
You are very welcome
I’ve commented on this previously a few years ago. I had a B12 test in 2014 which came back higher than the lab count.
That’s good that you had it checked. It’s not always a problem
Thanks for commenting, it’s good for people to hear
Mine is as always high too it came down into normal range when I treated my Sibo.
@@phwshopping1426How did you treat your SIBO?
I'm in the UK.. December diagnosed with high vitB12. Was double normal level. Took vitB12 tabs til Oct '23 , slowly coming down. No longer take tablets. Iron levels keep increasing, dropping for last 2 years. Just started iron tabs for 3 months, to have another blood test in Aug. Any ideas? Liver, kidneys normal. Cannot remember name , starts with M, blood cancer. Negative
Hi Doc, I've been recently diagnosed w seronagative RA. My B12 level is >2K & neutrophils have been low for 2 yrs now...is there a correlation between RA & blood disorder?
Short answer is no but RA and autoimmune are immune disorders so they affect the white blood cells.
My niece has a 2000 b12 along with pain in the abdomen and inability to eat. She has been referred to a GI Dr but it seems like she should go to a hematologist??
It is hard to say both could be appropriate.
Doc. Can consuming just 10 tablets of b12 1500mcg continue for 10 days and on day 11 checking serum b12 and its 1143. Are these tabelets culprit or something else??
100
@@swintegrative what do u mean by 100 sir?
Mean yes
It means it is likely
True I even know why. I always knew vitamin A excess was harmful as it's a teratogen.
My mom was diagnosed with aplastic anemia 12 years ago , shes on cyclosporine ever since to keep her rbc , wbc , platelets and other cells at normal range , when we tried to get her off cyclosporine her all blood counts dropped then dr kept her twking cyclosporine all this time,
But now all of suden 1 year ago her blood count dropped significantly, wbc is at 2.3 and platelets at 20 , hemoglobin at 80+ , shes now on transfusions .
Mim always took 1000 mcg b12 everyday with 1mg folic acid , could these vitamins be cause of problems ?
Mom took 80 mg of zinc for last 2 years for her macular degeneration,
I suspect that her copper is depleted , could this be the problem .
That sounds like a very fragile and complicated situation. Vitamin b12 and folate generally help support the production of cells in general through production to dna base pairs. That is about all I can say. I hope it helps.
My 4 y/o B12 was 1776 and 1808 5 days later.CBC, liver,kidney tests normal.Her pediatrician reached out to Hematologist and Geneticist who both refused to see her stating “high B12 in otherwise healthy child is no cause for concern” Her pediatrician does not know why her B12 is high but says her “newborn screening” was normal therefore he will not order anymore tests.She does not take any vitamins,injections,supplements etc.Shes a pretty picky eater, I’m 100000% sure this is not due to her diet and what she’s eating.Can she have naturally high B12 and it’s nothing to be concerned about or is there always an underlying issue?
Well there can be nothing to worry about. I think that is often the case but I can see why u would be concerned. There are genetic reasons for people to have elevated B12 too. It is hard to say much more than that with having all the information.
Also there may be something specific to pediatrics w regard to b12 transport but I am not aware of any.