Vasopressors: Inodilators, Inopressors, Pure Vasopressors, Methylene Blue, Midodrine

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  • čas přidán 27. 07. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    You can find the NOTES and ILLUSTRATIONS for this lecture on our website at: www.ninjanerd.org/lecture/vas...
    Ninja Nerds!
    In this lecture Professor Zach Murphy will be presenting on Vasopressors. We start this lecture by talking about the most common types of Inodilators including the indications, titration parameters, and advantages/disadvantages for Dobutamine, Milrinone, and Isoproterenol. The next category of Vasopressors we discuss is Inopressors. We will be discussing the indications, titration parameters, and the advantages/disadvantages for Epinephrine, Norepinephrine, and Dopamine. The next category of Vasopressors we will be talking about is Pure Vasopressors to include the indications, titrations parameters, and advantages/disadvantages of Phenylephrine, Vasopressin, and Angiotensin-II. The last type of Vasopressor we will be discussing is referred to as Methylene Blue, which will include an explanation on its indications, titration parameters, and advantages/disadvantages. We will also be having a brief discussion on how vasopressors can be commonly administrated to a patient including peripheral IV and central venous catheter. Finally, this lecture is concluded with a description of Midodrine, a vasopressor that can be administrated orally along with its indications and advantages/disadvantages.
    We hope you enjoy this lecture and be sure to support us below!
    Table of Contents:
    0:00 Lab
    0:08 Vasopressors Introduction
    0:36 Inodilators - Dobutamine, Milrinone, and Isoproterenol
    23:02 Inopressors - Epinephrine, Norepinephrine, and Dopamine
    43:10 Pure Vasopressors - Phenylephrine, Vasopressin, and Angiotensin-II
    1:07:35 Methylene Blue
    1:17:13 Methods to Administrate Vasopressors
    1:22:07 Midodrine - Alternative Vasopressor
    1:25:58 Outro: As Always, Until Next Time
    1:26:06 Comment, Like, SUBSCRIBE!
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Komentáře • 84

  • @narayanprasad5244
    @narayanprasad5244 Před 3 měsíci +7

    Every medical school in the world should close and just have students subscribe to this channel. I am an Australian Emergency Medicine advanced trainee preparing for my Fellowship examinations and I don't know where or what I would be without you!!!

  • @fionarob8371
    @fionarob8371 Před 3 měsíci +1

    Best video explaining vasopressors ever! I'm an ICU nurse trying to get into CRNA school and this video definitely helps a lot. Thank you for your hard work!

  • @TheGasPrincess
    @TheGasPrincess Před 2 lety +9

    You and your team are literally hands down the best out there. Thank you for all your hard work and for helping us all to become better medical professionals!

  • @lilanli5993
    @lilanli5993 Před měsícem +1

    So addicted to watching your videos everyday

  • @JorgeLuiz-qn3is
    @JorgeLuiz-qn3is Před rokem +2

    I'm from Brazil and i just wanna thank you for everything you do for people who whants to learn. Amazing man! Best regards!

  • @snugglynuts
    @snugglynuts Před rokem +4

    I work in the CVICU and this video has been super helpful in learning about the various cardiac meds. Big ups homie

  • @spanish_regime_4hundred363
    @spanish_regime_4hundred363 Před 2 lety +31

    Wonderful! Can you also pls talk about Impella and intra-aortic balloon pump? Thank you, Professor Zach.

  • @ricardocampbell8929
    @ricardocampbell8929 Před 5 měsíci +1

    I am currently studying for my CCRN test, and this video was very helpful in explaining the mechanism of action for some common medications seen in the test. Thank you and your team for putting this together!

  • @shahiramohammadi7284
    @shahiramohammadi7284 Před 2 lety +4

    I don't know how to thank you Zach you are so great👏🏻

  • @Vanessamichelle84
    @Vanessamichelle84 Před rokem +2

    love your enthusiasm in teaching, you keep my attention and make me enjoy learning!

  • @philorida
    @philorida Před 2 měsíci

    I'm enjoying your presentations. Not a wasted breath.

  • @mayamaan1
    @mayamaan1 Před 2 lety

    Please continue giving back to the Universe…The Universe will give it back to you. You have helped so many of us. I am getting ready to transition to a critical care and your lecture is valuable to my growth.

  • @darleen6258
    @darleen6258 Před 2 lety +3

    You are agreat Dr.
    You are the Best.
    Thank you very much

  • @aimz5479
    @aimz5479 Před 2 lety +2

    the best professor thank u for saving lives

  • @CaseyRoff
    @CaseyRoff Před 3 měsíci

    Incredible video guys! I feel like a lot of learning these things is spaced repetition, contextualisation and seeing the same topic presented in different ways. You do such an fantastic job with these drugs, especially the ones that act on multiple systems. The way you repeat the MOA is seriously great teaching, it makes me understand the principles so that by remembering something like, phenylephrine has strong alpha activity and mild beta activity, you can predict it's effect and side effects. Love it

  • @time2go465
    @time2go465 Před 2 lety +4

    This is so awesome from ninja nerd and Prof Zach , my cardiovascular disease exam is on next Friday and this and atrial fibrillation video just dropped right in time for my further understanding and revision 😄

  • @Alan-wl5de
    @Alan-wl5de Před rokem

    I love you. i am a pharmacist, the best lecture, ever. thank you

  • @michelleduane8841
    @michelleduane8841 Před 2 lety +2

    Wow! You love teaching and it shows. Ty for this great lecture. Awesome!!

  • @michaelbraccia4556
    @michaelbraccia4556 Před 2 lety +3

    GREAT LECTURE THANK YOU

  • @michaelmuller136
    @michaelmuller136 Před rokem

    Yeah, finished the Cardiovascular Pharmacology Playlist, that was interesting, thank you!

  • @ashnadesai6292
    @ashnadesai6292 Před 2 lety +2

    This helped me so much! Thankyou

  • @subashthapa8066
    @subashthapa8066 Před 2 lety +5

    I really enjoyed this lecture and learned so many things that would have taken me days to grasp from books...your style and presentation are both awesome and concise. Thank you

  • @driftinxer
    @driftinxer Před 2 lety +4

    thank you master 👍

  • @newmanlord7130
    @newmanlord7130 Před 2 lety

    I am getting the window of Vasopressor significantly from You Doc,
    This is Great Video Prof.
    Hi from Ghana.

  • @user-ym7fx9kc2b
    @user-ym7fx9kc2b Před 2 lety +2

    make more videos please am clinical pharmacy student your lecture is fantastic

  • @hibakamran3554
    @hibakamran3554 Před 2 lety

    thanks a million and zillions DR. zach you're a blessing :)

  • @lucianaguerra8367
    @lucianaguerra8367 Před 2 lety

    Great lesson !

  • @yusrahassan2363
    @yusrahassan2363 Před 2 lety

    you made this topic a piece of cake. thank u

  • @erinseawright9829
    @erinseawright9829 Před 2 lety +1

    This dropped at the perfect time for my med school curriculum😭👏

  • @theshapedexperience
    @theshapedexperience Před 3 měsíci

    thank you for this!

  • @rahuldas-sc8vs
    @rahuldas-sc8vs Před rokem

    Brilliant teaching Sir

  • @medicalbiochemistry_
    @medicalbiochemistry_ Před 2 lety +1

    Simply the best

  • @RUYINAETENGsMEDICDIARY
    @RUYINAETENGsMEDICDIARY Před 2 lety +1

    Well done!

  • @sweetgabaruby
    @sweetgabaruby Před rokem +1

    This video is very very good, I'm new to ICU, can you do a video on the medications use for intubation and why they choose them. Analgesic, paralytic, nerve blocking agents.
    Thank you

  • @formynation
    @formynation Před rokem +1

    No doubt a legend u are❤

  • @darleen6258
    @darleen6258 Před rokem

    Perfect. Thank you very much ❤

  • @zia735
    @zia735 Před 2 lety +1

    King in medical sciences

  • @rebeccasauer9191
    @rebeccasauer9191 Před 10 měsíci

    Excellent!

  • @gustavs495
    @gustavs495 Před 2 lety

    Thanks prof God bless you

  • @aliholguin
    @aliholguin Před 8 měsíci

    Amazing. Thank you

  • @judyjimenez9506
    @judyjimenez9506 Před 2 lety

    Yes … plz discuss Impella device, screen device , parameter , care of patient , risks and benefits … :)

  • @brunoteneos
    @brunoteneos Před 7 měsíci

    You're awesome!! Can't thank you enough

  • @ambiakhatunmehediimransumi7474

    the legend ZACH sir

  • @sonamdhondup5426
    @sonamdhondup5426 Před 9 měsíci

    Thank you for the great video

  • @borrah1281
    @borrah1281 Před 2 lety

    the best as always

  • @futuretimes805
    @futuretimes805 Před 2 lety

    Legendary zach

  • @LoanTran-hi1po
    @LoanTran-hi1po Před 2 lety +3

    What an awesome lecture!!!!

  • @parmindermann7876
    @parmindermann7876 Před 6 měsíci

    So knowledgeable 👏👏👏

  • @user-wm7iu1yb1l
    @user-wm7iu1yb1l Před 10 měsíci

    Wow interesting lectures

  • @archiemercado4289
    @archiemercado4289 Před rokem +1

    40/dead got me. LOLOL

  • @DoctorOck1254
    @DoctorOck1254 Před 2 lety

    Can you make a lecture about immunosuppressive drugs, your explanation helps me a lot

  • @josephryan3707
    @josephryan3707 Před 8 měsíci

    I watched all of your videos when I was taking anatomy courses and then tutoring anatomy. Now I watch your videos to help me be a good nurse in the ICU. Thank you

  • @lillianotuokwu5800
    @lillianotuokwu5800 Před 2 lety

    great❤

  • @theferaltaint5065
    @theferaltaint5065 Před rokem

    Great one Zach. As for AT-II, I’m with you. As a nurse, it would be very hard for me to advocate for such a drug in any critically ill patient. Especially if they are intubated and/or have any potentially worsening pulmonary pathology. Excess ACE-II can lead to micro and macro vascular endothelial dysfunction. This could potentially worsen any underlying SIRS response, contribute to a pro-coagulopathic state, etc. All of which could contribute to the development of ARDS, DIC, worsening vasoplegia, increased vascular permeability, etc. etc. etc. It just seems like an unnecessary risk to take when we have better options.

    • @theferaltaint5065
      @theferaltaint5065 Před rokem

      Lol and just as I finish typing my comment, you basically point all of that out. 😅

  • @DoccOtt
    @DoccOtt Před 2 lety +1

    Hey! Big fan! Really love the videos and how you make absurdly complex subjects so simple and easy to understand.
    Ive got three questions.
    #1 I get regularly scolded for saying dopamine is dose dependent. As i understand, internists say that dopamine’s dose dependant title was no longer accurate (according to some recent studies). Again, this probably has low impact on a patient that has already exhausted all other options, but why is this particular drug still named as an option if these potential side effects and overall effectivenes are this extremeis?
    #2. Based strictly on its mechanism on action and physiological response, should Levosimendan be considered as a possible inotrope?
    3. In a cardiogenic shock context (purely from an ischemic etiology) , wouldnt chronotropes and vasopressors induce higher myocardial oxygen consumption leading to a higher degree of tissue damage?
    Thank you!

    • @MultiNerve
      @MultiNerve Před rokem

      I can only answer #3, which is - yes. They are known for being bad if you put them in a peripheral IV. Levophed can cause someone to look like they're going through SJS/TEN if you have to push it through a PIV. It will cause massive sloughing of the skin around the PIV site

  • @oabouassy
    @oabouassy Před 2 lety

    Excuse me guys , in which order should I study physiology playlists in this wonderful channel ?

  • @drabdirahmanibrahin6021
    @drabdirahmanibrahin6021 Před 2 lety +1

    Thank uuuuuuuuuuuuuuuuuuuuuu

  • @darleen6258
    @darleen6258 Před 2 lety

    Please talk about Ischemic Heart disease

  • @jerlinnadar1581
    @jerlinnadar1581 Před 2 lety

    Need more video in pharmacology 🙏 plz

  • @Demothones
    @Demothones Před 2 lety

    My understanding is that MAP of 65 is for when you don’t know your patient’s baseline. If you do know your pop patient’s baseline then the goal should be +\- 20% of baseline. Is that correct?

  • @ishalmydream1786
    @ishalmydream1786 Před 4 měsíci

    Super

  • @Mina-Rofaeil
    @Mina-Rofaeil Před 2 lety

    Please add Heparin's notes and illustration on the website.

  • @LilFella67
    @LilFella67 Před rokem

    @Ninja Nerd
    Never used the blue infusion at my institution. Will the methylene blue infusion turn the patient blue after 1-3 days?

  • @JC-xk8vh
    @JC-xk8vh Před 2 lety

    @16:46 What do you mean never titrate against BP? Meaning use them as a monotherapy just to combat low BP? Can you please clarify? I am confused. TIA

  • @dawnsmith370
    @dawnsmith370 Před rokem

    I am researching this now and any comments appreciated. I am 59 female and only known problems is my recent bloodwork shows my RBC steadily climbing and now flagged high and my hemotocrit and hemoglobin has been flagged high for 8 years. Dr is wanting me to go for a sleep study next week something about oxygen🤷‍♀️. Also I have to get a thyroid ultrasound annually , it is enlarged and nodules that needs monitored and I have 2 doctors fighting over whether to take it out •. I prefer to keep my organs and no prescription meds.

  • @markdavid4897
    @markdavid4897 Před rokem

    Methylene Blue fixes many things inside the human body. Are the blood pressure increases caused by taking MB cause for alarm? Cellular respiration is improved with MB, so does one offset the other in terms of oxygen delivery? It would seem that MB would overall be a positive for the patient in most cases.

  • @hewhoknocks2880
    @hewhoknocks2880 Před 5 měsíci

    Man are you a cardiologist ?
    If so where ! I will travel the country to be your patient
    Let me know please
    I’m in Miami

  • @sorrymudabbir1659
    @sorrymudabbir1659 Před 2 lety

    how does vasopressors dilates pulonary arteries??

  • @paulmtae1738
    @paulmtae1738 Před 2 lety

    Please Sir can you make a video on MYOCARDIAL INFARCTION please

  • @purushottamparajuli842

    👍👍

  • @RealJonzuk
    @RealJonzuk Před rokem

    I wish salvia divinorum was studied for heart effects

  • @mrusurped5597
    @mrusurped5597 Před 2 lety +1

    I love u

  • @gayatrick2248
    @gayatrick2248 Před 11 měsíci

    I've a doubt regarding methylene blue

  • @sirenasirian4036
    @sirenasirian4036 Před 2 lety

    🌹🌹🌹❤️❤️❤️

  • @matt360360
    @matt360360 Před rokem

    You lost me at hello. 😅

  • @stevemitz4740
    @stevemitz4740 Před 2 lety

    I don't understand what stimulates or drives one to put silly ink "art"/ graffiti on a God designed body! It reminds me of walls in the black ghettos, marked up with "cool" crap art!

  • @Dolofonix
    @Dolofonix Před rokem

    Perfect. Thank you very much ❤