Beta Blockers | Mechanism of Action, Indications, Adverse Reactions, Contraindications

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  • čas přidán 5. 07. 2024
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    During this lecture Professor Zach Murphy will go into detail on how Beta Blockers are used to lower and control high blood pressure. This will include a brief discussion on the pathophysiology of hypertension (HTN) and how Beta Blockers target specific receptors to ultimately lower and control high blood pressure. We will then discuss the indications, adverse drug reactions, and contraindications for Beta Blockers.
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    #ninjanerd #BetaBlockers #Antihypertensives

Komentáře • 289

  • @ashleyprice2338
    @ashleyprice2338 Před 3 lety +84

    You're the only reason I'm going to pass pharmacology this semester. Your depth of knowledge and understanding astounds me with every lecture. This is my very first CZcams comment ever and it's well deserved!! Keep kicking ass!!
    THANK YOU!!!

  • @tylersimonek8752
    @tylersimonek8752 Před 3 lety +33

    He really fills in all the gaps that my professors seem to skip over. This guy has saved me so many times. I just want to remind everyone to like his videos and subscribe to his channel. I mean if you watched any part of his videos or the entire thing. It is nothing for us but helps him out so much. I appreciate this channel and all the work that goes into it. Keep up the great work.

  • @pennygodwin2962
    @pennygodwin2962 Před rokem +12

    I just came from my cardiologist’s office and wanted some information on beta blockers, which he just prescribed. Your lecture was done so well that I watched it to the end and was surprised at how understandable you made it. Thank you! I’m sure you really ARE helping those commenting below get through medical courses with how well you teach the material.

  • @videotrash
    @videotrash Před 4 lety +154

    I'm never not impressed when watching these videos. The breadth of your biological and anatomical knowledge is really astounding and enviable.

    • @gailspencer8497
      @gailspencer8497 Před 3 lety +1

      For some time (around Two years), I was maintaining my prescription medication to keep my high blood pressure not until this month I recently found about this t.co/GsO1JmyXtf
      therapy. A doctor has verified it too. Really dont require the drugs previously prescribed to me. .

    • @Winter_Wyvern1
      @Winter_Wyvern1 Před rokem +3

      That double negatives is never not confusing.

  • @jonyjoe6719
    @jonyjoe6719 Před 3 lety +4

    Am so blessed i found you 😭😭
    I am having exams in a month i want more PHARMACOLOGY LECTURES PLZ SR upload them you are the only teacher whom i understand pharma . No other channels helps me,😭😭

  • @alishaclasmartinez2639
    @alishaclasmartinez2639 Před 2 lety +5

    I have learned more from this video than i have from any teacher or book!! Your teaching style is amazing and so helpful!! I am hoping watching this videos will help me pass my advanced pharm class! keep the videos coming!!

  • @taramorgan4142
    @taramorgan4142 Před 3 lety +8

    I absolutely love this channel. It's the only thing keeping me sane through FNP school. I may have listened to "double block that AV node" a few too many times but it helped me remember not to give beta blockers and calcium channel blockers together!

  • @paulbieber7103
    @paulbieber7103 Před 3 lety +23

    Best medical lectures on the web. Great content, great attitude. Keep it up.

  • @suefuller3014
    @suefuller3014 Před rokem +1

    Thank you very much for taking the time to explain the three kinds of Beta blockers. For years I have taken atenolol for angina. Started in 1981. I am now 74 years old and have calcification in my heart. The doctor has taken me off atenolol and put me onCarvedilol. Your video is so good that I am going to watch it for the second time. I am very grateful to have found your video

  • @bijoyt.thomas5518
    @bijoyt.thomas5518 Před 4 lety +18

    Nebivolol: A Novel Beta 1-Blocker with Nitric Oxide-Induced Vasodilatation very unique among other class . Good tolerability.Nebivolol is approved in Europe/Asia/Africa and Middle east countries widely used . ( particularly in asthma and COPD patients where other beta blockers are contraindicated)

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  Před 4 lety +3

      That’s really cool!!! Thanks for sharing that!!!

    • @pamagujar183
      @pamagujar183 Před 4 lety +3

      Can you, please, explain "cytokine storm" as it applies to Covid19? Particularly IL-6 (interleukin6) and its medication anti medication. I think you're very brilliant and consider it a blessing to have you with us. Is there another way of giving donations that aren't done via internet? It's very important to help you with your mission...

    • @shamsfarhat7130
      @shamsfarhat7130 Před 3 lety +1

      Hi dear thanks so much

  • @komalkaur5815
    @komalkaur5815 Před rokem +2

    I have been watching Ninja Nerd for a few months now and i think no one can explain better than these videos man !

  • @SugarCube2003
    @SugarCube2003 Před 2 lety +6

    As someone who just started taking bisoprolol this video really helped understand what's actually supposed to be happening, what's going wrong and how the beta blockers will fix it as well as all potential risks! Big thanks! 😊

  • @dkish4
    @dkish4 Před 2 lety +2

    The best teacher ever I did learn this subject 40 years ago in Bucurest Romania ago, I remember all, you are amazing. Thank you

  • @willowwickham7713
    @willowwickham7713 Před 2 lety +1

    Another amazing video, keep up the good work! You’re getting my whole class through pharmacy school. You deserve a shout out at our graduation. I couldn’t thank you enough.

  • @Dr.SuppMaster
    @Dr.SuppMaster Před 3 lety +2

    I’m an Italian md, this is the best channel i ever watched. Amazing job! 🙌🙌🙏🙏

  • @toniencheff4046
    @toniencheff4046 Před 2 lety +1

    You explain it all so very well. You draw the map so completely between all the systems so when I making driving my car trying to decide which way to go I have your road map to make clinical decisions. You were great I love you

  • @Annedroid_VisorPro
    @Annedroid_VisorPro Před 2 lety +3

    I am a Dentist and I'm studying to take the Dental Boards! your videos are the only ones that help me comprehend better! I can't Thank you enough! You are the best!

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  Před 2 lety +1

      Check out the Discord! We have a section created for Dental students, with specific topics relevant to those studies! Plus, you'll find other Ninja Nerd community members who are studying Dental fields.

    • @Annedroid_VisorPro
      @Annedroid_VisorPro Před 2 lety

      @@NinjaNerdOfficial really? Omg thank you so so much! ❤️❤️❤️

  • @eirinimaggiorou8162
    @eirinimaggiorou8162 Před rokem

    You are the best tutor that I have ever had. Thank you so much, I presented β-blockers to my master program and I felt very confident after your video. Well done!!

  • @ederlyergino7411
    @ederlyergino7411 Před 4 lety +15

    You made my studying a very comprehensive one! I cant thank you enough! I'm taking my NCLEX soon and you are a huge help!

  • @owenmomanyi8314
    @owenmomanyi8314 Před 2 lety +1

    14 mins in and I just know I have myself a new tutor. Excellent. Bravo. I'm speechless

  • @anjayyadav6735
    @anjayyadav6735 Před 3 lety +2

    Love you Sir...How much complex is the topic doesn't matter. .He makes it simple in so many ways. ..

  • @amycoffin3841
    @amycoffin3841 Před 2 lety +2

    Love your content, it's saving me right now! Small point, but I learned that an indication for beta blockers in heart failure is to offset the ongoing effects of sympathetic activation in CHF. Obviously the sympathetic effects are good in acute settings, but in chronic settings the sympathetics are part of what leads to the pathophys of chronic CHF. I feel like that fills in a gap when you discuss indications!
    The ongoing compensation via autonomics can (paradoxically) lead to decompensation via physiologic/structural changes, but once the patient is decompensated you don't want to interfere with the autonomic compensation response because it is too little too late.

  • @nathanvanduiven5728
    @nathanvanduiven5728 Před rokem +2

    Starting my Pharmacy Degree next year and I can already see that your videos are going to extremely helpful.

  • @basantmonier4206
    @basantmonier4206 Před 2 lety +1

    You are such an amazing teacher, everything just makes sense after listening to your lectures, keeep up the great work

  • @ronaldob9097
    @ronaldob9097 Před 3 lety +1

    I love your in depth explanation and rationale for each drugs, very informative and easy to understand. well done and keep the good work. Well recommended. Good bless and keep safe.

  • @judef6272
    @judef6272 Před 3 lety +3

    this guy makes we want to study harder

  • @kinzaasghar9454
    @kinzaasghar9454 Před 3 lety +2

    No one in this world is a better teacher than you 😘jst jst brilliant way of teaching 💪👌 love you ninja nerd😘❣️

  • @evanap1797
    @evanap1797 Před 3 lety +1

    I whish I had found you earlier than 1 day before my exam, thank you still. It's so much clearer now !

  • @nnitinkumarr_
    @nnitinkumarr_ Před rokem +1

    idk if you'll ever read this comment but you my friend are a savior for all of us medical students.

  • @jelena5800
    @jelena5800 Před 3 lety +2

    Keep going man, you are brilliant. You helped me a lot to prepare my final tests.

  • @paulette1st
    @paulette1st Před 2 lety +1

    First CZcams comment, thank you for all your lectures you are absolutely amazing. All health professionals and future health professionals continue to benefit from your astounding lectures. I love your content- thank you x1,0000,00000

  • @SimiKaranvlogs
    @SimiKaranvlogs Před 2 lety +2

    I am preparing for Nclex and studying here to make my concepts clear … thankyou for clearing concepts

  • @brianedwards5113
    @brianedwards5113 Před 2 měsíci

    I can't thank you enough for these high quality videos you all produce!!

  • @omarqwasmeh5827
    @omarqwasmeh5827 Před 3 lety +3

    i really can't thank you enough man thanks for all the hard work u r putting in this channel and for your efforts god bless and keep up the hard work :D

  • @architasaha8917
    @architasaha8917 Před 4 lety +5

    Yes your teaching and clear concept make us rich. Thank you.

  • @souad_joubbane
    @souad_joubbane Před rokem +2

    Unbelievable how good your lectures are!!! Thank you so much ❤️

  • @muhammadjunaidali769
    @muhammadjunaidali769 Před 3 lety +1

    explaining complex concept in very simple way,fantastic.

  • @lourdesolvera6579
    @lourdesolvera6579 Před 4 lety +3

    Love how you explain things and it makes sense

  • @gimee0352
    @gimee0352 Před 4 lety +7

    I freaking love you, guys, can't thank you enough ❤

  • @deliarose5183
    @deliarose5183 Před 3 lety +1

    The best of the best lecture. Gold standard 👏🏼👏🏼

  • @inmortal009
    @inmortal009 Před rokem

    this man understanding of the topic is astounding

  • @bushrakhan2615
    @bushrakhan2615 Před 3 lety +4

    I am addicted to your videos Please upload more pharmacology lectures 💕

  • @irata8905
    @irata8905 Před 4 lety +12

    hey really greart vids im thinking about to show them to my profs and they would see how online classes could be actually good

  • @vikingwind25
    @vikingwind25 Před 2 lety +5

    I'm not a Med student but I love your presentations. I am a retired electronic engineer and now believe the human race runs on cellular MilliVolts levels and other chemical interactions I have yet to understand. Thanks!

  • @tsehayetesfaldet4066
    @tsehayetesfaldet4066 Před rokem

    you are the best teacher I have encountered in science. I really appreciate you.

  • @mylvalopes6045
    @mylvalopes6045 Před 3 lety +1

    This is amazing! I love the breakdown and it helped me make sense of it all

  • @fernandofranco7305
    @fernandofranco7305 Před 2 lety +1

    Very very clear explanation from the start up to the last part Sir!!!

  • @guzelkouki3929
    @guzelkouki3929 Před rokem

    There is no teacher greater than you I'm sure ... Thank you so much

  • @djuanaberuk9908
    @djuanaberuk9908 Před rokem

    Thanks so much for simplifying this in depth topic. You made it seem so easy.

  • @kanhucharandas4540
    @kanhucharandas4540 Před 10 měsíci

    Hi Sir! I am wishing you a happy teachers' day in advance as you are doing a invaluable work for the mankind.God bless you Dr Zach

  • @dranthonyasturi9790
    @dranthonyasturi9790 Před 2 lety +2

    You are the very best. Occasionally, when going over important concepts, it might be best to slow down a bit on the speed of your speech. Because you are so familiar and well versed in the subject, I can understand why you feel the need for speed in order to cover the subject completely in the short amount of time you have. Nonetheless, you are the VERY BEST lecturer I have ever encountered in my life.

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  Před 2 lety +1

      Some Ninja Nerds who have had issues with Zach's speed have reported setting the playback speed to x0.75 helps them! It's hard to contain his exuberance sometimes!

  • @paulastafford1642
    @paulastafford1642 Před rokem

    Learned a lot! I didn't know atenolol and metopolol were in the same generation. Great video. You explain things so well. Thank you.

  • @manthizen
    @manthizen Před 2 lety +1

    Definitely the best pharmacology lecture

  • @leenshammout2284
    @leenshammout2284 Před 3 lety +2

    Best teacher in the world ,Thank you so much ❤️

  • @beshertabbara3674
    @beshertabbara3674 Před 2 měsíci

    Thank you for the awesome overview. The labeling of the funny Na++ channel inside the pacemaker cell is "Ca++" (should be Na++) - around minute 23, 24 in the video.

  • @robertpugsley6326
    @robertpugsley6326 Před 2 lety +1

    I've just been diagnosed with SVT. I currently have DVT, PE, COPD-2, PAD and CAD.
    Checking what side effects Beta Blockers have. General, instead of being bedridden or close to it. I'm now going to be able to slow my tachycardia but now loose more quality of life due to diarrhea, increased edema, vision problems (had Glaucoma since 2000),...
    It seems the best move now is to purchase a 38' because I will never have any quality of life ever again.
    My entire family is gone, what friends I had are no more. I live in a van with the minimalist of life's aids with no Healthcare luxuries.
    From what I could understand and learn, the Second Generation might help...but again, too many negative side effects especially living alone.
    Praying doesn't work anymore.

    • @meghageorge8197
      @meghageorge8197 Před 2 lety +1

      Hoping for your recovery and stay strong. Being alone can be tough especially with health problems but I pray you find the will to push through!

  • @cathum
    @cathum Před 4 lety +1

    Awesome - and thanks for your time and effort.

  • @mariamroy
    @mariamroy Před 2 lety +1

    subscribed! it would be worth it to watch your videos, things are logically explained and make so much sense

  • @chemistchauhan
    @chemistchauhan Před rokem

    Beautiful fact he enjoys teaching ......lots of love to him❤️

  • @fawazd
    @fawazd Před rokem +1

    Extremely nice and clear clarification. Tank you .

  • @sueyun375
    @sueyun375 Před 3 lety +1

    Great job!!! love your all your lectures.

  • @sanybr5470
    @sanybr5470 Před měsícem

    You explain better than all of my university professors 😅thank you so much

  • @shivanishivani4705
    @shivanishivani4705 Před 2 lety +1

    thankyou for the beautiful explanation.
    please make videos on every topic of pharmacology, microbiology.

  • @zakiidibshey3394
    @zakiidibshey3394 Před rokem

    This is a legacy u leaving behind, we really appreciate ur lecture

  • @sujatakumari8052
    @sujatakumari8052 Před 4 lety +1

    No one can explain any topic like u do 👌👌👌👌👌

  • @SariShares
    @SariShares Před 4 lety +1

    I take carvedilol and lisinopril for high blood pressure. I have mild diastolic dysfunction and mild aorta widening as well as long QT Syndrome. I love your videos and indepth explainations!

  • @kellycairns7025
    @kellycairns7025 Před rokem

    LOL, simple concept, right? I'm off to get my alcoholic beverage to act on my overstimulated brain cells. I truly appreciate how this is all broken down VISUALLY so that I can truly grasp the concepts. This is the first and only site I go to for pharm and theory. Thank you so much!

  • @desibelajar4365
    @desibelajar4365 Před 3 lety +2

    Your are inspiration to teach and can integrated among draw and explain very cleary...

  • @yusranawal8455
    @yusranawal8455 Před 2 lety +1

    its the best cology video i have watched. want u to make more on other topics like antibiotics and CNS

  • @mumunubogen2439
    @mumunubogen2439 Před 2 lety +1

    How do you study for this kind of presentation? your Method of study is behind all this powerful, simple presentation. I just begin my Pharmacology 1 at PNG Uni of Med & Health Sciences. Thank you for lifetime proff

  • @niazwali8169
    @niazwali8169 Před 4 lety +4

    amazing proffesor Dr consultant u are sir

  • @reshmifrancisvadakkan8706

    This is just the perfect way of explaining beta blockers.

  • @jenniferjaneliving
    @jenniferjaneliving Před rokem

    Thanks for helping me through nursing school!!

  • @dkish4
    @dkish4 Před 2 lety +1

    You are Number one teacher ever well-done DOC

  • @OmarAli-py3pq
    @OmarAli-py3pq Před 4 lety +3

    As always I LOVE you guys keep it up 👏🏻❤️❤️❤️❤️❤️❤️

  • @marielouise966
    @marielouise966 Před 2 lety

    YOU are awesome, the greatest Ninja Nerd in the world !

  • @vinayakkapatral4246
    @vinayakkapatral4246 Před 4 lety +1

    Awesome!!! Zach master is excellent!

  • @sujatakumari8052
    @sujatakumari8052 Před 4 lety +2

    I want to say just a huge huge thank u ,how u prepare all the topic sooooooo welll 😊😊😊😊😊

  • @fromkitchen8600
    @fromkitchen8600 Před 4 lety +2

    thank you for such a nice presentation.

  • @dhirubhansali
    @dhirubhansali Před rokem

    Outstanding teaching..i m loving to see ur all videos

  • @komalkaur5815
    @komalkaur5815 Před rokem +1

    This guy's videos are blessings in disguise ;)

  • @Peter-vn5jq
    @Peter-vn5jq Před 3 měsíci

    I got prescribed propranolol for anxiety after alcohol withdrawal, and, true to form, taking them has started causing me anxiety, lol. They do work really well for reducing the sweats, shakes, tachypnea and tachycardia, but they don't directly impact the mental aspect- one could even say that they approach anxiety from the other direction that benzos do. Benzos calm the brain, which calms the body, Inderal calms the body, which allows the mind to calm down. So now I'm watching videos like this one, so I can calm my hypochondriac ass down further, lmao. It's helping, too, so thanks. I'll dazzle my doctor with my knowledge during our next visit.

  • @amandadrinsinger6121
    @amandadrinsinger6121 Před 3 lety +2

    These are super helpful and I love the presentation. Thanks for being a great teacher!

  • @amandavitaglian5859
    @amandavitaglian5859 Před rokem

    You're amazing, thank you for everything you do and for sharing your knowledge

  • @tomnguyen8639
    @tomnguyen8639 Před rokem

    Amazing knowledge and teaching technique!!!

  • @katiecherry5503
    @katiecherry5503 Před 2 lety +2

    More pharma please dr zach we need videos of analgesics and Local Ansthesia and many moreeee
    also please continue the microbiology series
    general medicine
    General surgery topics will be appreciated
    Thank you for the explanation and the effort that you put in your videos

  • @niazwali8169
    @niazwali8169 Před 4 lety +4

    nice sir amazing method of teaching please continuos sir pharmacology especially cardiovascular system pharmacology

  • @nat7870
    @nat7870 Před 2 lety +1

    YOU'RE MAKING MEDICINE FUN! THANK YOU

  • @aleksandardzunic8174
    @aleksandardzunic8174 Před 2 lety +1

    FANTASTIC LECTURING SKILL!!!

  • @nilkiani7334
    @nilkiani7334 Před 4 lety +2

    I love watching your videos😍your job is amazing👍🏻👌🏻

  • @shahiramohammadi7284
    @shahiramohammadi7284 Před 3 lety +2

    Love this lecture

  • @abdullahkhan12679
    @abdullahkhan12679 Před 5 měsíci

    Much impressive lecture.
    Keep ur efforts continue. ❤

  • @indianasb59
    @indianasb59 Před 3 lety +1

    Intriguing. My BP before propanol was high with migraines and anxiety. Now my BP is either still high or super low. My thinking is leaning to me to Pheochromocytoma.

  • @rubaalbarghouthi
    @rubaalbarghouthi Před 4 měsíci

    Many thanks 😊 amazing informative video as usual 👌 wishing you all the best 👍

  • @vaibhavithorat7283
    @vaibhavithorat7283 Před 3 lety

    Heyyyyy superbly taught. Loved it. Watching your videos from India.

  • @aishvaryasivakumar2996
    @aishvaryasivakumar2996 Před 3 lety +1

    You are a life saver !!! keep making more videos

  • @mjnavarro1252
    @mjnavarro1252 Před 4 lety +5

    Great video - very informative! I am confused on the effect of sympathetic stimulation on beta cells of the blood vessels in the video (8:05). I think it causes vasoconstriction, but in the video you said it is vasodilation which supports increase in BP too. Am I missing something? 😬

    • @mohammedjeouit6483
      @mohammedjeouit6483 Před 4 lety +3

      blood vessels have different types of receptors (alpha 1 & beta 2...) which are localised as so:
      alpha 1 are localised in arterioles all over the body expect coronary arteries and vessels that supply the CNS ,which have beta 2 receptors...so that when you have an activation of sympathetic nervous system or you are on shock the vasoconstriction does not affect the vessels supplying the brain and the heart thus maintaining their function....
      (I guess)

  • @acacianorison
    @acacianorison Před 4 lety +1

    Great video , Can you please talk about the Beta blockers and eye lens accomodation for long distance.💝👍

  • @user-tb5su6mv3s
    @user-tb5su6mv3s Před 4 lety +3

    Thank you so much you are just amazing ❤️❤️❤️

  • @mistymay1043
    @mistymay1043 Před 2 lety +1

    This dude is amazing. 💯💯💯Thank you!