How do Beta Blockers Work? (+ Pharmacology)
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- čas přidán 17. 06. 2024
- Antihypertensives are a class of drugs that are used to treat hypertension. Antihypertensive therapy seeks to prevent the complications of high blood pressure such as heart attack and stroke.
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Answers:
1.)C 2.)B 3.)D 4.)D
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This pharmacology lecture covers topics such as pathophysiology of hypertension, regulation of blood pressure, cardiac output, systemic vascular resistance, baroreceptors, alpha 1 & beta 1 Beta 2 receptors, vasoconstriction, vasodilation, . Mechanism of action of antihypertensive drugs and their side effects; adrenergic antagonists; alpha & beta blockers, centrally acting adrenergic agents, dihydropyridine & nondihydropyridine calcium channel blockers, loop, thiazide, potassium-sparing diuretics, renin inhibitors, angiotensin converting enzyme (ACE) inhibitors, angiotensin II receptor type 1 blockers (ARBs), endothelin receptor antagonist, dopamine-1 receptor agonist, peripheral vasodilators. Drugs mentioned include; Atenolol, Bisoprolol, Nadolol, Carvedilol, Propranolol, Metoprolol tartrate, metoprolol succinate.
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FUN TRICK: If a BB starts with A-M = Selective. If a BB starts with N-Z = Non-Selective (B1+B2). The only exceptions to this rule are Carvedilol and Labetalol (B1+B2+A1 non-selective), and Nebivolol and Betaxalol (NO release vasodilation for Nebiv, and CCB-like response for Betax). You now know effectively every BB receptor!
That's an awesome trick! Thanks for sharing it with everyone!
Plz tell me wt is AM NZ
@@medicallecturersforgraduat1417 its drug whose initials from start A-M,,i.e drugs such as atenolol,bisoprolol etc and those whose initials lie between N-Z eeeh
It only works with the generic names though (eg Bisoprolol (generic name) versus Zebeta as its brand name. So don’t get confused. Great tip!!
@@medicallecturersforgraduat1417 alphabet letters a-m
i am watching all your videos and seriously so obsessed and thankful i found u!!! you deserve a million subscribers. I swear no one can teach as succinctly as you. BLESS
This video is by far the best video. It helped me so much with my exams in pharmacy school!
This video was the most helpful pharmacology video I have come across! Thank you so much!
Thanks for watching!😁
Thank you for another helpful video! Please keep making more!
I hv this on repeat every time...u hv made my pharmacology content much easier to remember..can’t wait to watch your other videos ...
Thank you so much for your support! More videos will be coming! :)
Best ever among other beta blockers explaning videos. short and simple. sweet!
Thank you so much for making this video. I was having a hard time understanding how beta blockers work. I’m glad I clicked on your video. Within 15 min I was able to understand how they work. Your video is straight to the point and so easy to understand 👩🏻⚕️🙌👍👍👍👍👍
Thanks for watching! Feels good to help! More videos coming soon!😁
This video is a LIFESAVER! Thank you so much haha I am studying for exams at pharmacy school!
Thank you so much. Your efforts are highly appreciated ❤️
Please keep making these videos! I’m taking pharmacology this fall and I am already learning a lot.
Glad you enjoy them! @Kathy Thang , And Yes! We will keep them coming!
Awesome presentation. I loved the graphics and simply put explanations of beta blockers. Thank you.
Yes exactly graphical presentation plus voice tone make videos series very pleasant and gave them a very high ranking among the other
Omg!!!! This was sooooooooo helpful!! I am a nursing student and was stressing over pharmacology but you my friend just made that stress go away!!! plz continue to post these very helpful videos PLEASE!! :)
Glad the video helped!! More videos coming out soon!
@@DrugChug yessssssssssssss!! 👏🏾👏🏾👏🏾💖💖💖💖🙏🏾🙏🏾🙌🏾🙌🏾🙌🏾😁😁😁😁
Superbly well done explanation. Very informative.
Thank you for watching!😁
Finally found the perfect video! You're a lifesaver. Thanks so much.
You're welcome Missmaiv! Glad the video helped!😁
Just discovered your explainer videos...LOVE them!
Thank you so much for the support!
these are amazing for public speaking. Highly recommended!
Perfect vedio.... visualisation is amazing.. and easy to understand
crystal clear! perfect video!! thank you sir!
You're very welcome binbinky78! Glad it helped😁
Excellent explanation , thank you. ❤
Glad it helped! Thank you 😊
Woww you explained it so easily and so quickly.thanks!
Nice explanation in simple way
Hi Jagjeevan! Thank you for your support!!
Wowsers! Great stuff! Thanks
Great explanation about beta blockers😍😍 Thank you!!
That was Great video about beta - blockers. In CZcams, i found only this video, which can be learned accurately and clearly . Thanks a lot for making this video.🥰🥰
Very well explained
Great explanation!👍🏾
Thank you!
1-A-M selective beta blocker
2-N-Z non selective beta blocker ( N se start non selective)
3-Nonselective beta blocker with extra property
intead olol- lol present mostly except nebivolol tilisolol celiprolol
saved my time so much !!
Thank you so much for watching!😁
1-carvedilol 2-b1
3-metoprolol succinate
4-d
Great video man
Keep it up dude
Thank You again! Appreciate the continued Support!
Great explanation ❤
As I'm currently on beta blockers this is very helpful.
Now I know why I get so dizzy on standing up.
Fine once I'm walking
Very good information.
keep it up.
Thank you! Will do! More videos to come😁
Great video
you're amazing! thank you!
I have a exam tomorrow morning you really saved me thanks a lot ♡
Informative video 👍
THANKS ALOT GOD BLESS YOU!
Very useful..thanks
You're very welcome! Keep on learning!
Great info.
Thank you for your video. Great help!! I am a student in Korea. I believe your lecture would be great help not only for me but also for students who live in korea. And I would like to translate in korean and share online. If it is OK, I would make sure to cite original source, your youtube channel. Hope to hear from you soon. Thank you!
thank you so much very interested
Youre welcome! Glad you enjoyed it😁
thanks
Thank You so much
Thank you for this video! I have Atrial Fibrillation and my electro cardiologist just put me on Metoprolol Succinate and Flecainide. The question I have is, do you have a video on Flecainide? I’m 58 years old and I haven’t had a need to take any medications until I developed A-fib recently. I’m just trying to educate myself about these drugs that I’m now having to take for the condition I’m experiencing. Thank you, and please keep the information coming on your channel.
How your dr realised you have AF pls
Very informative
Thank you soo much ❤
Excellent information I wish these high-paid doctors would take the time to explain this to you they just are like here's a bunch of pills good luck
Thank you for the support Mark! Appreciate the kind words😁
Thank you!
Thank you for watching!
Gr8 information for me
thank you.
You're welcome! Hope it helped!
Thanks!!
Thank you it's really helpful for pharmacy students
Glad you enjoyed it! More videos coming out soon!
verysimpleway-explanation-witheasy-understanding
Thank you for watching!😀
Thankyou so much, this is so helpful , you git a new subscriber :)
Thanks for the sub!! :)
Thank you sir
Great channel. Can you do a video on Alpha Blockers
Thank you for you support! @Miter Saw More videos coming soon, Alpha blockers are on the list to do! 😁
good stuff
good thsnk you dr
Thank you .good video. Can you tell me why patient is having bisoprolol and diltiazem together ?
Excellent!why carvedilol preferred in CHF?and how does rebound tachycardia happen??tnx.Njokweni(South Africa 🇿🇦)
I was put on propranolol because of heart palpitations caused by PVCs. It’s amazing how fast it works. I wonder what causes the PVCs. I always felt like I was having a panic attack, all day, every day for no reason. Not anymore 😁I usually hate rx because I always have the horrible side affects, but the only one I have with this is being cold because it slows the hr.
شكراً جزيلاً 🌼🌾
كان مفيداً جداً، أرجو أن تتم ترجمته للغة العربية قريباً
tukram ainek madmozal Maya
Good presentation.
Sir you have mentioned, in heart failure only 3 medicines ie, carvedilol bisoprolol metoprolol. So why nebivolol cannot be used bcz it could better replace carvedilol as the later even block beta2 receptor also. While the nebivolol do same as carvedilol without blocking b2 and since no lung issues
Supprbbb!!! N loved it
I got 4 points on your quiz. 😊
Woohoo!! Great job! @Aki Ra
Thoughts on taking selective B1 Beta blocker while on Clenbutrol?
This video is the best video about the beta blockers I like this vedio
Water solubility and lipid solubility about the beta blocker you missed it if you can apply it to this video
Hi I am in sri lanka
I you want I can give ideas about tha videos
My email address
Smtslakshan@gmail.com
I have a question, In what cases would non-selective beta-blockers be prescribed vs selective beta-blockers, given that many of the cases are heart-related issues? Thank you for your videos btw, super helpful and to the point, keep up the great work!! :)
Great question! You have to understand that the non-selective are older drugs. This means some insurance companies want to pay for them first, because they are cheaper. So unfortunately money is a big factor in therapy.
Also, some of the nonselective have benefits, for example: propranolol can be used for hyperthyroidism and social anxiety.
Hope that clears some things up!
@@DrugChug definitely cleared it up! Thank you so much for your help! :)
Non selective timolol somatol and propanolol
sir i am having a hard time finding the mechanism how B1 causes contraction in the heart ? any recommendations any one plz .
From A to M its B1 (think of it as the first part of the alphabit)
great
So when adrenaline binds to alpha 1 receptor it causes vasoconstriction, did I understand right?
Bisoprololl has vasodilation effect aswel!!
Central nervous system side effects can be caused by some beta blockers lipid soluble, right?
OMG i was given propranolol just for my anxiety and it helps.
Why anxiety part is not covered in this video? Should i continue or switch to benzos? Which one is safe for anxiety?
Good day. My doctor advised me to take propranolol 10mg once a day for about 1month for my chestpain. I’m now on the last 2pieces of medicine.. I’m just worried about the withdrawal syndrome after this.. Is it okay to stop it without tapering? It’s just a low dose anyway
Where I found solve of these short quiz ? I want to make sure of the solution
Can you answer what blood vessels alpha blockers cause vasodilation
Hi, is it true that discontinuing Propranolol can result in abrupt heart attacks even at low doses like 40 mg ?
Hi!😁
The risk will always be there when abruptly stopping any beta blocker. The risk is decreased if it's a lower dose, and a less duration of use (using it for 1 week versus 3 months). It never hurts to slowly taper beta blockers off!
I use propranolol for anxiety and I had wpw I no longer have wpw
On it for thyroiditis overactive will it also help lower my anxiety and heart rate/ shaking
we can also recommend arjunaaarista ayurvedic medicine
How does constriction of the lungs decreases Blo0d pressure?I am confused
Could you make a video on Prostaglandins please
Yes, more videos are planned to be released in due time! Stay tuned!
I can't donate blood anymore because my pulse or heart rate is high. What is the best beta blocker?
I.ve been put on beta blockers as I have ischemic heart disease and small blood vessels disease my BP is high one minute then six hours later it's low
So how would u safely dismiss taking any beta blocker without the risks???
Best combination for 5mg amplodipine+ 40 mg proponol? please tellme sir.
Can carvedilol 12.5mg give to elderly patients? Does carvedilol slow down the heart function n the dilation of blood vessel to cause lesser blood to kidney n causing trouble to the kidney as kidney receiving less oxygen? How long can this medicine given to elderly patient? As the lung receptors are blocked n causing less function to exchange oxygen, could this result the blood cell in the body and organ deteriorate because of less oxygen and nutrients reqiired? Also, since carvedilol put a brake on the heart function, could this eventually worsening the heart n causimg death to elderly? This video is great, excellent explanation. One more question, since carvedilol is an old medicine, does it still widely used?
Why are those three beta-blockers used in treating heart failure rather than different beta-blockers? Also great video, very informative and simple.
Great Question! @Calum
For a general answer: These 3 beta blockers proved to be superior in clinical trials for heart failure, and because of these trials, they are recommended.
The only other thing is that Carvedilol has antioxidant effects, which help reverse structural damage to the heart, which would surely help our heart failure patients!
Hope this helps!
@@DrugChug Thank you, it makes more sense. How do the antioxidants reverse the damage? And can most structural damage be reversed using the mechanism?
Can you take propranolol 10 mg for one time use?
Freaking legenddddddddddddd. Thankssss mannn
Have been wondering forever why carvedilol causes a vasodilation. Nobody ever explained that sometimes BETAblockers can work on the alpha receptor as well. Thank you so much for this video!
Glad it cleared things up! 😁
How does B1 blockers cause hypoglycemia?!
I use prazosin for sleep at night. Nothing else works for PTSD sleep disorder. It also helps me during the day to be more down regulated.
Sir how come beta blocker block alpha 1 receptor ?
Do you have any pdf for the notes
Blimey
Eating healthy and keeping fit seems to be the priority here.
I'm 60 and I think twice about even taking paracetamol.
I don't even know what my doctor looks like ❤