Thiazide Diuretics | Mechanism of Action, Indications, Adverse Reactions, Contraindications

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  • čas přidán 16. 04. 2020
  • Official Ninja Nerd Website: ninjanerd.org
    Ninja Nerds!
    Join us for our discussion on thiazide and thiazide like diuretics as we continue our lecture series on cardiovascular pharmacology and how to treat Hypertension (HTN). During this lecture Professor Zach Murphy will go into detail on how thiazide and thiazide like diuretics are used to lower and control high blood pressure as well as decrease excess fluid in conditions such as congestive heart failure (CHF).
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Komentáře • 161

  • @khaireeystastybites2636
    @khaireeystastybites2636 Před 3 lety +17

    My best ever medical channel. This guy deserves a medal award 🥇

  • @KCMDWannabe
    @KCMDWannabe Před 3 lety +23

    I always had trouble with understanding why hyperglycaemia results from thiazides! This makes so much more sense you legends. Thank you for the explanation

  • @muskandeshwal9299
    @muskandeshwal9299 Před 3 lety +16

    Man really .......never ever seen someone... explain so beautifully......hypertension is such a crucial and difficult.....and he explained it like it’s nobody’s business

  • @brianwilkerson2513
    @brianwilkerson2513 Před 4 lety +83

    Love, love, love your videos. Would love to see one covering anti-psychotics and anti-depressants. Keep ‘me coming!!

    • @Ellymiao2
      @Ellymiao2 Před 3 lety +3

      Omg YES

    • @mrityunjayrathod1714
      @mrityunjayrathod1714 Před 3 lety +2

      Yesss plzzzz. Antidepressants

    • @PhoenixRN
      @PhoenixRN Před rokem

      I was thinking the same thing. Wonder why he hasn't done them yet... literally nothing related to psychiatric medicine, no physiology/pathophysiology/pharmacology...

    • @johnlanzidelle1940
      @johnlanzidelle1940 Před rokem

      @@mrityunjayrathod1714 bb

  • @transientpassenger3796
    @transientpassenger3796 Před 3 lety +7

    Beast, clearest, most complete explanation on thiazide diuretics I have ever seen, and I have seen quite a few. You, sir, are a huge blessing. Thank you so much!

  • @B0RICUA3
    @B0RICUA3 Před 3 lety +3

    Hi, I just wanted to say that the level you explain everything is so on point. Your videos are amazing. Thank you for all the lectures!

  • @aylagul7755
    @aylagul7755 Před 3 lety +4

    How much effort is involved in this video can not be described in words. Thank you. Apreciate it 🙏

  • @FightingDancerify
    @FightingDancerify Před 4 měsíci

    Hello, just a quick note from me: I study pharmacy in germany and thank you so much for your videos! Hours of reading through textbooks were avoided thanks to your amazing content! I'm also an auditaury learner and this helped incredibly! Thank you so much!

  • @nish209
    @nish209 Před 4 lety +2

    My man is pumping these videos out 😍😍😍😍

  • @cokiewestfall8878
    @cokiewestfall8878 Před 3 lety

    Whew😅😳 I feel like I just ran a marathon 🏃🏽‍♀️but what a race it was! 😀 you truly are gifted....so very grateful for your crystal clear teaching on a topic that can be so confusing! Many thanks! 🙌🏻

  • @CaptivaLP
    @CaptivaLP Před 3 lety +4

    I love your pharmacology videos!!! Thank you so much. I would really appreciate a video about Antidiabetics and Antimycotics 🙌🏻

  • @netra8311
    @netra8311 Před 4 lety +1

    The best way anyone could ever explain...ur the best ❤️ ❤️

  • @AbdurRahim-cn2sv
    @AbdurRahim-cn2sv Před rokem

    I have no words to explain your beauty of explanation.

  • @joaovictorsouzadelima7041

    Great class as usual! Thanks Zach!

  • @arielmandelblum
    @arielmandelblum Před 2 lety +1

    Once again, top tier video and a stellar explanation!

  • @surbhi3290
    @surbhi3290 Před 3 lety

    Thank you so much for clearing all doubts by excellent teaching and creative correlating diagram patterns..God bless u!!

  • @dr.rehanabashir2886
    @dr.rehanabashir2886 Před 4 lety +3

    U r best teacher thanks so very much for ur lectures u make them so easy to understand keep going plz

  • @redietyonas3079
    @redietyonas3079 Před 3 lety

    You are a gift a gift from GOD to medical students all over the world!!! and may HE help you to keep up the great work.
    Thanks to every one who helped make this video you guys are amazing thank you once again.

  • @Aerospatial
    @Aerospatial Před 4 lety +1

    Always enjoy your videos. You're an amazing teacher

  • @erumaijazmohiuddin7482

    You are an amazingly talented guy!!! Made it look so easy..

  • @barborastankova3965
    @barborastankova3965 Před 4 lety

    Best explanations ever, thank you so much.

  • @Joy-y31
    @Joy-y31 Před rokem

    I am understanding better what's going on with my own body. Thank you guys. 😊

  • @kasjopea95
    @kasjopea95 Před 4 lety +6

    My pandemic-times challange: watch all your videos (again 😜) 🧠 XXX from 🇵🇱

  • @samuelwestphal2336
    @samuelwestphal2336 Před 3 lety

    Amazing class, always helpfull! Thank you guys

  • @LesterBarrett
    @LesterBarrett Před 2 lety

    I am liking these lectures more and more.

  • @parsa6230
    @parsa6230 Před 4 lety +13

    Best teacher EVER
    Thank you
    Continue for Ever ❤️

    • @prakharnikam3981
      @prakharnikam3981 Před 4 lety

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  • @user-qp2br8lh1h
    @user-qp2br8lh1h Před 4 měsíci

    i am a big fan of you Zac, You are a fab teacher. keep up the good work

  • @nandababuraj825
    @nandababuraj825 Před rokem

    If you weren't there, concepts would have been a nightmare. Thankyou so much for being the light.

  • @AriHoresh
    @AriHoresh Před 4 lety +17

    Came here to like the video!

    • @prakharnikam3981
      @prakharnikam3981 Před 4 lety

      EnterMedSchool this is the most sorted (very short vedio) on how corona virus infection developed pneumonia which leads to death... Let's make people aware of it
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  • @Ravenclaw1213
    @Ravenclaw1213 Před rokem

    FABULOUS!! THANK YOU!!!!

  • @HA-et3ox
    @HA-et3ox Před 3 lety

    What an amazing explanation.. thank you so much 🌹

  • @hiransenevirathna9034
    @hiransenevirathna9034 Před 3 lety

    best explanation ever.thank you very much.

  • @hidayatullah8964
    @hidayatullah8964 Před 7 měsíci

    Much love and respect for You Sir Really Amazing teaching and massive method of teaching❤

  • @anushkafan9609
    @anushkafan9609 Před 5 měsíci

    Which words describe it I don't know I think there is no words that's able to justify how clear cut concept and enjoy full lecture ❤❤❤ thank you 👏👏☺️. I'm unconsciously deep into this lecture ❤ thank you sir sincerely from my heart 🙏🙏🙏🙏🙏🙏

  • @codyprince7378
    @codyprince7378 Před rokem

    Amazing video!

  • @airinkhanam3007
    @airinkhanam3007 Před měsícem

    Excellent!!

  • @soumengmail3542
    @soumengmail3542 Před 4 lety

    it cleared my many concepts

  • @bijoyinihalder6826
    @bijoyinihalder6826 Před rokem

    your videos are life-saver❤️

  • @jameskantor0459
    @jameskantor0459 Před 2 měsíci

    Excellent video , thank you! I have been started on chlorthalidone to reduce urine calcium for kidney and bladder stones .

  • @darleen6258
    @darleen6258 Před 2 lety

    Really perfect. Thank you very much from Germany

  • @Kat-yg3ok
    @Kat-yg3ok Před 3 lety

    Amazing video!!! Trying for days to understand all these but failed. With these video, all sounded so easy!! Thank you!! Keep going!! :D :D :D :D

  • @becherkapuka1149
    @becherkapuka1149 Před 4 lety +1

    Thank you,you are the best.

  • @ayeshaiqbal778
    @ayeshaiqbal778 Před 4 lety +3

    Liked before watching!!! Biggest fan!!

    • @prakharnikam3981
      @prakharnikam3981 Před 4 lety

      Ayesha Iqbal this is the most sorted vedio on how corona virus infection developed pneumonia which leads to death
      czcams.com/video/5ZhnRSP8_Xg/video.html

  • @sueyun375
    @sueyun375 Před 3 lety

    Great job!!!!

  • @docnerd4261
    @docnerd4261 Před rokem

    Ninja Nerd for life 😘

  • @klah2u
    @klah2u Před 3 lety

    I didn't understand half of what you said but it was totally fascinating

  • @ehe3653
    @ehe3653 Před 5 měsíci

    thank you, it helps so much :D

  • @user-ro6ef7gd8i
    @user-ro6ef7gd8i Před 10 měsíci

    🌿😩 amazing as always

  • @prithviyadravi4092
    @prithviyadravi4092 Před 2 lety

    This video helped a lot sir ❤️
    Thank you 🙏🏻 so much sir

  • @mohammediq3796
    @mohammediq3796 Před 3 lety

    i swaer u r the best teacher dude

  • @darkmoon3646
    @darkmoon3646 Před rokem

    This guy makes me wanna learn these for fun

  • @shivalikatal5839
    @shivalikatal5839 Před 3 lety

    Sooo amazing thankew sooo much ♥️

  • @shahiramohammadi7284
    @shahiramohammadi7284 Před 3 lety

    Love your videos

  • @naomifavor2887
    @naomifavor2887 Před 2 lety

    👏good job zach

  • @a30s
    @a30s Před 4 lety +2

    Best explanation sir.
    Thanks alot.
    Keep growing.

    • @prakharnikam3981
      @prakharnikam3981 Před 4 lety

      anil sunka this is the most sorted vedio on how corona virus infection developed pneumonia which leads to death... Let's make people aware of it
      czcams.com/video/5ZhnRSP8_Xg/video.html

  • @LMTheMachinePR
    @LMTheMachinePR Před 5 měsíci

    Thanks! 🙏🏻

  • @drkillydarknson7947
    @drkillydarknson7947 Před 2 lety

    Thank you so much

  • @drdianellyspintobenamaraap5935

    Y0u are amazing, a lot of passion, mucho Amor en esta carrera, gracias, the best of the best

  • @KiranRajpurohit
    @KiranRajpurohit Před 4 lety +1

    can u pls upload a video on neoplasia chapter.
    that is a important topic and i would be very thankful if u do that for me,
    i liked the way u teach, u make our concepts clear.
    thank u for helping us in this way.

  • @fariabashir155
    @fariabashir155 Před 3 lety

    Ur vedios are speechless sir👍

  • @neelhinsu7971
    @neelhinsu7971 Před 4 lety

    As a pharmacist to understand most of the topics. We need more videos other pharmacology topics

  • @architasaha8917
    @architasaha8917 Před 4 lety

    Excellent

  • @sugardreams17
    @sugardreams17 Před 4 lety +1

    Loops and potassium sparing drugs too please? This discussion was amazing. Thank you!

  • @VinodSV
    @VinodSV Před rokem

    I am a BP patient and doctor suggested chlorathaliodine and within a month my URIC acid raised to the roof (14.5) and wanted to know what was the reason. Now I know what caused this sudden spike.
    Thanks Very much

  • @nilkiani7334
    @nilkiani7334 Před 4 lety

    Well done 🤓👌🏻👍🏻

  • @samanea8514
    @samanea8514 Před 4 lety

    Thank you

  • @Chaudharys1
    @Chaudharys1 Před 3 lety

    This is crazy hard.

  • @Raj_Nirvaan
    @Raj_Nirvaan Před 3 lety

    Amazingly coooool

  • @whiteeagle7509
    @whiteeagle7509 Před 3 lety

    Many many thnx bro.
    If u make surgery lecture,it will help us more.plz.

  • @thesadeem4759
    @thesadeem4759 Před 4 lety +2

    Thank u

  • @kamalchandrangari6793
    @kamalchandrangari6793 Před 3 lety

    thank you sir

  • @yazminmojica4458
    @yazminmojica4458 Před 3 lety

    BRAVO 👏 👏👏👏👏Muchisimas gracias, Bendiciones 🙏

  • @niazwali8169
    @niazwali8169 Před 4 lety

    nice sir g amazing very helpful

  • @agounimouiz9197
    @agounimouiz9197 Před 2 lety

    The best ever

  • @palshah3509
    @palshah3509 Před 2 lety

    Thank you lifesaver 😘😘😘😘

  • @architasaha8917
    @architasaha8917 Před 4 lety

    Great.

  • @rishabhjoshi9136
    @rishabhjoshi9136 Před 3 lety

    thanks

  • @Pro1truth
    @Pro1truth Před 4 lety

    Thx 👍🏻

  • @alexanderngala4507
    @alexanderngala4507 Před rokem

    Wow! Wow!

  • @nsas955
    @nsas955 Před 3 lety

    You are great

  • @morsz6829
    @morsz6829 Před rokem +1

    At 6:37. PTH facilitate the Ca2+ reabsorption through both the luminal membrane Ca2+ channel & vascular membrane Na/Ca pump, resulting in increasing Plasma Ca2+, but shouldn't the plasma Na+ be reduced due to exchanging action of the Na/Ca pump? I am confused about why they are both increased in plasma concentration?

  • @PS-sf8tw
    @PS-sf8tw Před 3 lety

    U r the best

  • @erdurserin3291
    @erdurserin3291 Před 3 lety

    thanks thanks a lot

  • @fariabashir155
    @fariabashir155 Před 3 lety

    love uh sir

  • @lesliecontrerasrojas1138

    love.

  • @Favourite571
    @Favourite571 Před 4 lety +2

    Pls @ninja nerd science make a video on apoptosis and necrosis. I will really appreciate 🙏

  • @mohammedbarket1622
    @mohammedbarket1622 Před rokem

    thnks boss

  • @Ali-gk8mq
    @Ali-gk8mq Před 2 měsíci

    For the metabolic alkalosis, does the H+ move from the blood to the tubule cell because of concentration gradient when the electrical gradient pulls the H+ into the lumen of the tubule. And does it move passively or is it facilitative diffusion? Thank you for the help. Your videos are a god send!

  • @juliarampelsberger7889

    We love you

  • @griselgaspar6904
    @griselgaspar6904 Před 3 lety +1

    Amazing work again! Thank you! I just have one question: You mentioned that in Diabetes DI the ADH is working fine but the receptors are not. My understanding of DI is that ADH is not working and that is why the body is not retaining water? At least this is what I recently read in my disease process class AKA Adult 1.

    • @colinbusbee6265
      @colinbusbee6265 Před 3 lety +1

      There are two kinds of DI. One is nephrogenic which is a kidney issue and the other comes from a lack of ADH production.

  • @Aya-fk5tz
    @Aya-fk5tz Před 4 lety

    Can you make a video discussing metabolic and respiratory acidosis/alkalosis

  • @sebastianflorezmed
    @sebastianflorezmed Před rokem

    Every single day I wonder myself why does this guy does not have a nobel price for education

  • @dghdhdhdjdkksmd1066
    @dghdhdhdjdkksmd1066 Před 2 lety

    تم سماعه كاملا

  • @barrybaker9090
    @barrybaker9090 Před 3 lety

    Is there interstitial space in the DCT? Did he just miss it out or do it on purpose?

  • @rachana7060
    @rachana7060 Před 4 lety

    Can u please upload a video on cell injury

  • @OmarAli-py3pq
    @OmarAli-py3pq Před 4 lety +3

    I’ve spent all day on corona virus videos of you guys, all your videos are pieces of art ❤️❤️❤️❤️❤️

    • @prakharnikam3981
      @prakharnikam3981 Před 4 lety

      U will know in a very simple sorted manner in short what actually happens in corona virus if there is something wrong let me know it...

  • @PharmawArfa
    @PharmawArfa Před 6 měsíci

    Yayyy 👏🏿

  • @mariyamarshad9696
    @mariyamarshad9696 Před 2 lety

    But thiazide act on distal convoluted tubule by inhibiting NCC so how can you say that sodium and Cl, reabsorb more in proximal convoluted tubule and reach less amount of Na,Cl in the collecting duct ?? Plz explain ( distal comes after proximal tubule)

  • @tolasaraji6474
    @tolasaraji6474 Před 2 lety

    Best

  • @ritiknikunj8352
    @ritiknikunj8352 Před 3 lety

    Sir complete the lectures on all diuretics