Furosemide: Mechanism of action

In this video we explain the mechanism of action, pharmacokinetics, indications, contraindications and side effects of Furosemide. We use simple explanations and diagrams that are easy to understand, aimed at helping medical students and healthcare professionals of all levels.
Timestamps:
00:37 - Mechanism of action
10:22 - Pharmacokinetics
12:21 - Indications & Contraindications
14:47 - Cautions & adverse effects
17:53 - Summary
Furosemide belongs to a group of medications known as loop diuretics. Loop diuretics cause an increased production of urine by inhibiting the reabsorption of fluid and electrolytes. This is achieved by inhibiting the sodium/potassium/2 chloride co-transporters located on cells within the ascending limb of the loop of henle. Inhibition of these pumps causes fluid and electrolytes to remain in the kidney tubule so they can be excreted in the urine. Furosemide also has vasodilatory effects which contribute to its therapeutic effectiveness. Furosemide is used is oedematous states such as acute pulmonary oedema, peripheral oedema and ascites as well as resistant hypertension. The adverse effects are mainly attributed to the loss of fluid and electrolytes.
Thank you for watching and I hope you found this video helpful, be sure to check out our videos on pharmacology, and if there are any topics you would like us to cover then please leave a comment in the comment section below. We really appreciate your feedback as it helps us to design better quality videos.
Click the link to show Animated Medicine your support and buy them a coffee: www.buymeacoffee.com/AnimatedMed
Although this video is designed to provide education, it should not be used to guide clinical practice, treatment or medical decision making. These videos are designed to provide a detailed overview of each topic, and although a lot of research goes into each video errors can occur and medical practice, medical information and protocols may change over time, which is why it is important to follow local and national guidelines. These videos do not constitute medical advice, medical advice should be obtained from an appropriate healthcare provider or senior clinician.

[@winstonforbes3]

What an excellent video. Thank you for explaining so clearly.

[@AnimatedMedicine]

Thank you for your feedback Brian, I hope you found the video useful.

[@user-il1zi7go7k]

Continue for the clear explination🌱

[@silvio4pierce]

Awesome project about the different medicine, as well as the signs, symptoms and diagnosis. I love the way you explain the mechanism of action. It's rare to come upon such fine and easy to comprehend videos. Where can we send inquiries about desired themas (email)?

[@muhammadaamir9030]

Great sir, please keep uploading videos...

[@AnimatedMedicine]

Thank you for your feedback Muhammad, I’m working on more as we speak. I hope you find these videos of benefit.

[@AnjaliSharma-qk8ir]

It helped a lot. Thank you

[@AnimatedMedicine]

Thank you for commenting Anjali, I am pleased you found it helpful.

[@waqarhussain6932]

if i am mot wring from 15:30 less insulim relase due to less pottasium will cause hyperglycemi not hypoglycemia!! ? can u techek plz

[@vandalynfleming8189]

8 7oup