B Cells 3 - Maturation

www.handwrittentutorials.com - This tutorial explores the maturation of the B-Cell from the stem cell through to a mature B cell. The interaction with the bone marrow stromal cell is also discussed. For more entirely FREE medical tutorials and accompanying PDFs visit www.handwrittentutorials.com

[@Soccasteve]

Why can't more teachers be helpful like this? They seem to make this stuff way more confusing than it has to be.

[@yasharmashayekhi1094]

Thank you so much for this video, you literally went through a 3 hour lecture in 5 minutes. Absolute legend.

[@harpinmartin]

Yes, that's correct. The antigen independent phase is in the bone marrow. The antigen dependent phase is in secondary lymphoid tissue (which includes lymph nodes). The antigen dependent phase can be considered "Activation", but its all part of the continuous maturation process.

[@kiezheichoumisachan]

Sanjukta Ghosh i think activation comes first then the B cell can differentiate into a plasma cell

[@muleesha]

you have no idea how much you've helped!!! thank you so much sir!

[@darshikasharma2112]

Sir u are having an amazing teaching skill u told everything so comfortably with good pace to understand

[@OrriG]

This was so helpful, I have an exam on this tomorrow! I'm going to redraw your awesome diagram.

[@MrBrowneyedBeast]

Very great summary, simple, to the point, and easy to understand

[@bodycareforhealth8656]

you are brilliant thanks so much for your clear descriptive teaching
karen

[@ermarizjaducana9076]

Your tutorial sir is not complicated. Thanks a lot

[@kaitlyncocuzzo607]

Wow a 2 hour lecture I didnt understand clear as day in 5 minutes

[@yesyeshyes]

I think you just saved my prelim grades THANK YOU SO MUCH

[@juniorneal3456]

Thanks for the vid, this helps a lot.

[@griffin0124]

Thank you so much for the video,it helps me a lot.

[@meiremm58]

So Great! i'm painful that i didn't know you before!! Thank Youuu :D

[@arinarakhteenko579]

awesome review thanks!

[@syrineskhiri8216]

thank u , you save my life

[@jjojjorge]

Any videos on osteoblasts and piezoelectricity ?? Thanks.

[@MsEmichelle]

THANK YOU SO MUCH!!!

[@leenaalfares1161]

Thank you ❤️

[@carreraGT92]

Hold up, don't B cells mature in the bone marrow and then become activated in the lymph node?

[@bridgetneema5593]

Thankyou!!

[@mohammedalkhalaf9189]

thank you sir

[@rahulgoyal2439]

U said one b cell produce only one type of immunoglobulin than how come mature b cell have both igm nd igd on their surface????

[@anindyaguha9018]

IgM and IgD will both have the same specificity

[@manishadachhepati687]

Thank you so much

[@kevinwandago4339]

thank you sir!

[@ahmedkhalil8624]

why are there 2 different BCRs on the same B cell ??

[@jamiecoleman773]

It think it is the same. The first is just the pre-BCR form, which then develops into the BCR

[@bbartukoglu]

Thanks

[@taibaalsaeed1907]

Thanks alot

[@DrSanjeevPandey]

Extrordjnary presentation

[@aiswaryapanicker3938]

Nice video but make it more clear.many of the words I can't understand.it would be nice if the picture and the labelling should be written little more bigger.

[@davidkalman5868]

Thanks! :)

[@israaali747]

Thanks for this lecture but B cells full maturation occur in the bone marrow therefore, they called B referring to bone marrow and they exit form the bone marrow as mature naive B cell which migrate to the secondary lymphoid organs surveying for foreign antigens and when they meet that antigen they called mature B cell but not naive
Also you do not point to the positive and negative selection which is an absolutely important process in B cell developement

[@mohammedzoheb5299]

Cudnt help but notice how your voice sounds a lot like the actor Paul Bettany! xD Great video btw

[@jaclyngordon8031]

Very helpful! thank you!