Unlocking the Power of Longevity: 3 Hacks for a Longer Life
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- čas přidán 25. 08. 2024
- Much of what is claimed about lengthening lifespan in the longevity spaces comes from highly questionable animal models.
Do we live a longer life by going into a state of dormancy, like the famous worm, C. elegans?
Do we attain immortality through transdifferentiation like the biologically immortal jellyfish, Turritopsis dohrnii?
Or do we eat a chemically defined and optimized diet with no deviations, live in a specific pathogen-free bubble and get a 24/7 on-call personal doctor like the lab mouse?
Despite claims that the oldest old die from a general principle of senescence, the best data show that all humans die of specific definable causes.
We should begin the search for longevity not by trying to find a universal principle of senescence across all living organisms, but rather by studying the reasons humans die of the specific causes they die of in the real world, how to prevent those causes, and how to stay healthy as we expand lifespan.
The current snapshot of the leading causes of death in Western societies is in a dynamic flux where cancer has long been replacing heart disease as a leading cause of death and where that too is now giving way to a diversity of many causes as human lifespan begins to converge back on its natural length -- something that had been enormously disrupted by the Industrial Revolution and we are only now recovering from.
The medical model has done wonders by treating heart attacks in the emergency room, and if mainstream medicine can claim to have cleaned up the puss-filled unrefrigerated milk problem of the 1800s and early 1900s, then it has two major claims under its belt. Aside from that, however, it did more harm than good.
How do we know? Because the NUTRITION that eliminated the major infectious disease killers BEFORE antibiotics and vaccines came on the scene could have served as wildly low-hanging fruit to battle the diseases that took the place as the major killers for the last nearly 70 years.
This presentation covers the low-hanging fruit of nutrition for longevity, how to take it to the next level with nutritional optimization, and DIY home strategies for putting yourself on the path to find your own highly unique personal super-unlock that will unleash your own personal potential for a long and healthy life.
To dive even deeper into the super-unlock part of the equation, check out my article and video, How I Found My Health “Super Unlock” After 20 Years of Research and 20,000 Genes Tested here:
chrismasterjoh...
The world needs more people like you!!!! Thank you for the overview.
Had no idea there was a link between cod liver oil and antibiotics. This video was something else, wholesome, helpful, with data-dense graphs. Thank you so much, keep it up!
Fantastic summary. And also free. Only 10% of folks who watched this liked it..where’s the love?!
It's more narcissistic, lazy, and stupid then lack of love. Everyone knows it would be right to rate videos if you watched a majority of it. People just click on the next one. Generally the highest I've seen for positive input is about 14% but even crap videos tend to get at least 4% positive. Negative input helps channels also but they no longer show that as a number.
I always Like CM’s excellent videos
5% now - probably because he does such deep dives. It’s dense and he’s a talker/researcher. Good stuff though.
You've inspired me
@@Santa-ny1yp i like only the videos if there is some useful info for me which i wanna save in and comeback and rewatch later probably multiple times.
I find having the slides front and centre aid in understanding the points discussed. Thank you for that, Chris. All the best
Outstanding. From a long time follower pre PhD
Thank you Chris! This was excellent!
You know what else is a hack for longevity? Praying and repenting to our Lord Jesus Christ!
I've followed Chris for years and just realized he is Orthodox Christian. My wife and I became Catechumans recently. All glory to the one true God!
Question: does taking NAC along with other supplements help or inhibit their absorption?
I will pray for you brother
Excellent video! Will watch this one again!
Love your channel. I’ve watched all your videos. This is by far the most informative, helpful, and applicable. Watched it twice. #KickAss100YrOld
Couldn't agree more with how you view longevity.
Amazing insight.
Thank you so much for this abundant information🙏🏼
You are an amazing human being. God bless you
Thank you for this great video, complete, well explained a Genius work
1.A few random thoughts.
What if the lack of ATP is actually the ATP leaking from the cell? I believe there is some evidence of this if you read about cell danger response mode?
2.I have been exposed to Thousands of pod cast and medical journals and studies and the most common denominator of all the diseases is what insulin is doing, as in amounts, what is resistant and what is sensitive.
3. What comes first, insulin resistance, or excess uric acid, what if uric acid is a marker for too much, or to little autophagy?
4. Could low or sluggish bile flow be one of the main drivers of poor nutritional status because we wouldn’t properly be able to break down the nutrients? Could fatty liver cause the poor bile flow?
i also have doubts about uric acid as a marker
Uric acid is a very important marker for a few things. The carb addiction Doc recently did an episode on it. Highly recommend.
Amazing Chris! People are lucky to have you laying this all out. What are your thoughts on eosinophilic cationic protein as a marker for food intolerance for people with ongoing skin conditions for instance? Paul mason speaks about this test as well. Would love your thoughts on whether you think it is accurate. Thank you!
FWIW I would also suggest the other major technology advance from the late 1800's onwards was the advent of industrial water and waste water treatment in greatly reducing many water borne infectious diseases. Not directly medical I agree, but closely related.
Nice presentation. Thanks for uploading.
Chris, thank you for this great video. I am a long time fan and love your videos. You are the best, and this is one of your best videos.
Agreed.
Hello Chris, I’ve acquired the slow COMT gene mutation which means the enzymes ability to metabolize catecholamines is greatly hindered. I recently stumbled across a course suggesting to eliminate catechol containing foods, ie dark black blue purple and red berries red cabbage tubers cacao black / green tea , coffee , black beans , cumin , strawberries , pecans , pistachios buckwheat , it basically narrows down a minimal amount of foods that are acceptable , it is advisable to abstain from dairy consumption and meat due to excess tyrosine phenylalanine and tryphophan which converts to dopamine. I’m not sure what to eat, it suggests peppermint rosemary chamomile , salycilates which reduce catecholamines cruciferous vegetables and citrus legumes grains and rice (I have a gluten sensitivity supposedly according to a gi test but no noticeable symptoms after consuming wheat) they recommend flavonoids and genistein but no soy? I eat soy but I have low estrogen as a male they recommend the diet centers around fruit and roots, i tried eating only potato’s for a day but to no avail my symptoms remained. I’ve had horrible insomnia for years and complex trauma I’m particularly sensitive to stress and environmental toxins moreso then those around me. I don’t know what to do?
@@emectar1773Thanks for sharing, I’ve tried a multitude of supplements, including: adaptogens (ie Bacopa, ashwaghanda, holy basil) lemon balm, chamomile, magnesium (threonate+glycinate) glycine, taurine, Lithium orotate to no avail, i still use choline and creatine for the cognitive benefits they infer. It seems too good to be true but I will consider trying TMG, I’ve entertained the idea of doing so but figured my problems may be entirely psychological. May I ask, how many mg do you take, what have you tried previously , what is your diet like and what particular symptoms have you experienced ? At my worst I’ve bordered on psychotic symptoms particularly paranoia which is implicated in excessive dopamine levels, irrespective of this I’m particularly fine tuned to memorize and problem solve when presented with difficult information / tasks, fortunately my cognitive processes are enhanced and I’ve acquired an elevated IQ but under moments of intense stress my thinking can become i irrational, I’ve felt this way since I was young. Sorry for the long post, thanks for replying
@@emectar1773my homocysteine is low so I’m not sure if TMG would help but it wouldn’t hurt to try I suppose. From my understanding SAMe and mag speed up the COMT enzyme but they haven’t helped me.
@@emectar1773 Slow comt do not do well with methylated substances. I have multiple slow COMT genes and do a wide variety carnivore diet, including dairy. Health and wellness have dramatically improved. If i take any methylated vitamins i get anxious and overwhelmed easy.
@@Jwhite198620Interestingly, those with a slow COMT mutation are advised against meat consumption considering animal protein is high in the amino acids tryptophan tyrosine and phenylalanine which convert to the respective catecholamines, dairy seems to give me bouts of acne most likely because of the naturally containing hormones and estrogens. It baffles me because for most of human history and in virtually every culture people consume animal protein and almost every food contains a certain degree of these amino acids which are absolutely necessary but I suppose moderation is key. My methylation panel is optimal, I have low estrogen and homocysteine
TLDL anyone have the 3?
1. Eat a lot of ox testicles, pig intestine, and foie gras for micronutrients.
2. Take freezing cold shower in the morning and dip in icy lake once a week.
3. Jog barefoot and shirtless in the forest for grounding.
Bumb
Great video. Twenty one minutes in and so far simple enough for me to share ;-)
Great information as always. I use Coconut water for potassium, low calorie, very high in potassium.
Bad its too high in potassium so will cause imbalance and deficiency pf magnesium
I am take before and or After every meal potassium chlorid Salt kelp and its staple my bloodsugar
What about lectins and oxylates.
Brilliant presentation Doc. Thanks
Great content and perspective. Thank you.
I don’t want to divulge too much info, but I do want mention that how we speak (language) and what we consume(hear & watch) also plays a role in Logentivity !
you are taking about mental stress which also fast aging
@@mahfuzurrahmansourov984 stress is not what I was referring to, but I agree it is part of it...
Excellent presentation Chris, just like to add that the blue zones theory has been widely debunked, might be worthwhile casting an eye over?
You are very knowledgeable however most people aren’t smart enough or patient enough to absorb knowledge the way and density you relate it.
Calling out Sinclair in the first 2 minutes. Love it
Awesome work man ! Kudos ❤
I do question if mouse chow is their optimal diet what studies show this? And why does something as basic as glycine supplementation increase their life span?
I take potassium chlorid Salt kelp milk thistle before and or After every meal for stable bloodsugar
I'm curious if the crowd has any sources for high quality real-life human condition mouse studies. I've worked on murine heart disease models before and the IRB was corset tight on supplementation modifications i.e. high dose selenium or anything really. Anybody done a mouse study with a McDonald's high preservatives and high pesticide and bud light diet, then metabolic profiles and epigenetics or would the med community just refuse to publish the study since the diet would be irreflective of past studies? I might just try something like this before giving up my PhD and becoming an insurance salesman or fitness model.
please don't become insurance salesman, have self respect
Youre the best! Will be there b-fraday sales for your substack subscriptions?
44:04 Natural multivitamin
17:00 someone please explain Finland on these charts, why is it such an obvious outlier?
Chris! When can we expect to hear back if we have been waitlisted for bio opt? I’ve tried to sign up multiple times over the past month or so and filled out the form but have never heard back. Thanks!
Chris, the 19th century began on 1 January 1801, and ended on 31 December 1900, the 20th century began on 1 January 1901, and ended on 31 December 2000?
How much cod liver oil do you think was giving to sick people during that time?
Hey Chris, can taking Glycine pure powder and Modified Citrus Pectin together cause hypoglycemic type symptoms?
Not senescence but pathologies mediated in part by senescent cells?
Hey my brother in law paid $75 as advance on your book several years ago. Where is it.
Okinawans are blue zone, but eat a shit ton of pork. so the whole meat/protein thing you're probably right about.
Is the shift to cancer just living longer or changed environmental exposure (e.g. technology - radiation?, nutrition?)
I hate this overused word, but multifactorial is my guess; introduction of industrial seed oils, pollutants and other environmental stressors, metabolic dysfunction, dysfunction in energy metabolism pathways as highlighted by Chris, stress itself.
The various contributors probably converge to cause dysfunction in certain specific biological mechanism. One hypothesis is that it's mitochondria and metabolic related (Thomas Seyfried) in which they argue genes mutation is a downstream effect. I think there are more to it so a lot more to discover in the future.
3 things 1 hour later
👏👏👏👏
While reading on biotin, saw an old paper(think 1942) that it caused fat liver if used with other B's but taking pancreas stopped fat liver ! Have tried cod liver oil and fermented CLO but no improvement. Eating cod liver (taste good) feels like helps. Am wondering if ok to eat liver if high last 2 iron labs but ferritin 35-43? Or get too much vite A.
What color are your eyes?
@@joshhiett7419 , eye colors? Brown, but change color, was told gold, orange, greenish but mostly brown. Why?
Colors besides blue, grey, or brown indicate iron dis regulation in the liver (sub clinical cholestasis) dietary iron and retinol are implicated in this. TUDCA is a good solution
@@joshhiett7419 oh, is there more places to read about this? Had purchased some urine test strips and a few times had positive bilirubin, so wonder if bile or other problem. Anyone know of good home testing or urine teset strips "brands" or sources?
❤️❤️❤️
Astaxanthin
I recently added cod liver oil to my supplements.
Just finishing off my first bottle.
Mostly because I wanted to try retinol as vitamin A, and not just beta-carotene, which most supplements has for it.
I don't know if it really matters. But it can't hurt as long as you don't overdose it.
I'm sure cod liver oil still workes the same as in old times. We have just forgotten about it.
Homemade Bone Broth - Liquid Gold People!
I make it sometimes, but don't have access to quality grassfed animal bones, even regular bones are too expensive, and it take a lot of cooking to make it gelatinous. I just buy collagen powder.
Didn’t realize the Bible is a historical document…
TMI
How the f are we testing this stuff for free?