New Research Shows Artificial Sweeteners Mess Up Your Gut? | Educational Video | Biolayne
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- čas přidán 12. 04. 2022
- Link to study discussed:
pubmed.ncbi.nlm.nih.gov/35208...
Blautia Coccoides may have positive health benefits: pubmed.ncbi.nlm.nih.gov/33525...
Blautia Coccoides is decreased in obese/T2D:
pubmed.ncbi.nlm.nih.gov/32209...
Blautia Coccoides may improve intestinal barrier function and decrease inflammation in mice:
pubmed.ncbi.nlm.nih.gov/34962...
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Artificial sweeteners helped me loose 70 pounds,along with CICO- I'd be pretty pissed if my zero A&W left the shelf... Commenting for the algorithm ✌️
People who freak out about the gut health bs about artificial sweetners always seem to neglect that being fat is profoundly worse than having some problems with gut bacteria. Get your weight down as a priority, then worry about gut biome and micros and shit. Its orders of magnitudes more important to get weight under control. You got it right :P
Well done!
Congrats
@@x3r0h0ur I have gut problems at the moment . I am also quite overweight , eat alot of crap and drink way too much . Do you think if I changed my lifestyle ate healthly exercised lost the weight and quit the booze my issues would fix
@@markcoughlan2233 Virtually everything will improve if you do that.
I did my bachelor's thesis about Rats' gut microbiota. Sure, it was only bachelor's thesis, but the key point I understood while doing it, was that we know very little about gut microbiota overall - especially within humans.
Agreed. It’s a whole different universe.
Don’t discount your hard work and research because of an authority based fallacy. You don’t need to have a bachelors or a Masters degree to be able to put together objective based research and facts. Your opinion matters!
Way ahead of me. I dropped out and went to mechanics for the Army.
I understand you are saying, "we are not rats."
one thing we do know however is that rodents process artificial sweeteners very differently from humans
HOLD THE PHONE!! A study just proved that your gut biome changes a bit when you change your diet a bit? MIND-BLOWING
Ending my junior year in undergrad Dietetics, taking a Nutrition Research and Methodology class this semester and it feels awesome being able to (somewhat) understand the scientific research lingo finally! Your no BS, honest approach to relaying information is refreshing.
I've been "taught" to fear sucralose for years. That chart you put up shows such little variance between the control and sucralose groups, that I think I can let that go now. Thanks Layne!
Sucralose raises blood sugar. I work in a nursing home and a diabetic resident snacks on sucralose candy every night. His blood sugar is in the 300s in the morning before he eats anything.
Thanks for the info Layne. Your channel is refreshingly objective.
Thank you for educating people on how to actually interpret research papers
Whenever you conduct a study and find no differences between groups... you pretty much have to make up something so journals pick it up for publication.
As you said: "If you torture the data enough, it will confess to whatever you want."
Great video. You are so dissective in your comments....👏👏👏
Discovered your channel through your appearance on Spencer Cornelia's channel. Going through a backlog of your videos and really like what you're doing. Pumping the algo.
Big fan, love how you approach fitness, I hope your channel keeps growing bcuz you definitely deserve more recognition & views!
Stunning open-mindedness and impartial scrutiny - Norton once again demonstrates his ability to hear, consider, and be open and professional. 👌 This requires a spine and integrity!
Since sucralose is not metabolized and is excreted in feces, they should do a study on whether sucralose makes poop taste sweet. If confirmed, I will make low cal poopsicles for my next family function!
🤣🤣🤣🤣
Mmm, centipops.
“Poopsicles”... Sir, you’ve won the internets today!!! 🤣🤣🤣👊👍
Hmmm maybe thats why Mr Hanky the Christmas Poo is so nice lol.
naturally sweetened fecal microbiota transplants.
Thank you as always for sharing your expertise!
Appreciate these breakdowns chief
great video! digested the info to the T! thanks for your videos i love them!
Great discussion.
Good stuff as always!
I'm listening to one interview you've given and really appreciating your info. Keep up the good work!
And, yes, I'm commenting for the algorithm, too.😂🎉
Great explanation and information
Outstanding as always.
Great video as always sir, much appreciated.
Great video as always
I love these new research videos!!
More good content thanks always love to see your videos
Thanks for the info really appreciate it!
More knowledge = smarter gains. Thanks for putting in the work again.
Wow. Thanks for the info.👍🏾
This is the best science based fitness channel out there.
I'm curious what a study comparing water vs sucralose vs sucrose would show
I teach this too
Have you seen renaissance periodization? They’re even more nerdy
Coach Greg needs to see this.
I enjoy your information. Keep up your no bs way. Too little of it around
Commenting for the algorithm because I love these videos.
💗🙏🏻 for the algorithm and your channel✨
Took me only 1 minute and he makes already a lot more sense than most fitness youtubers
Thank you for your work sir! I used to be so afraid of artificial sweeteners because I didn't know better and the fear mongering amongst my friends who went to the gym didn't help. Also, commenting for the algorithm XD
Subscribed!
I hope you'll one day reach 1mill subs
Good stuff.
Layne, I must commend you for keeping abreast of so many areas of research and staying sharp with your research analytical skills so many years after completing your PhD. And you're not working in academia, right? Not that one has to be in academia to remain a critical thinker, but hey, you know what I mean! Good job man!
I really like your videos! Keep up the work!
Can you make a Video about which supplements you can take? Except creatine, I'm taking it for years☺️
Thank you.
Love ur stuff and wow I use ur food tracker !!! F eeeen amazing app thx u !!!!
You mean nutrition coaching app 😬
Good stuff
For the algo. But also artificial sweeteners are a huge part of my diet - thanks for this
Thank you
Yes! TY!
Doc NBS m….thank you…I appreciate how you do the hard work for us that really want to know the truth.
Thanks
For the algorithm!! Great Video!
You're a beast Layne
I have been subscribed. I love the use of artificial sweeteners in moderation like everything else in my diet. It is just one of many tools I use to loose or maintain my weight.
How many packets do you use per day?
@@bobbyadkins6983 Probably only 6 a day depending on what I'm doing. If I'm making low cal desserts, more. If I'm just just drinking diet soda, a lot less.
Man, I love these non controversial videos.
If you do enough studies you can pretty much find anything is bad for some people. I think it's about time people stopped worrying about artificial sweeteners.
For the algorithm! Thanks for all.
What many readers don’t understand is if you compare the effect of your intervention on 100 different variables to a 5% confidence level you will get ~5 variables showing a significant difference due to just random variation. To me (without reading the study), the differences they found between water & Sucralose consumption groups sounds like random variations. In my experience, if something is physiologically significant you’ll see large, consistent differences across time in many of the tested variables. This study didn’t have that!
Intelligently put. A lot of people don't understand that "statistically significant" means there was only a 5% chance of seeing the result. That's a pretty decent change. If you try to find a needle in a haystack, you'll probably find it after a lot of digging and manipulation of data
@@Collinpawns See also: xkcd 882 and 1478.
This study looks to be one of those that was farming factors to find anything that had a significant difference. Run analysis on enough factors, especially with a small sample size, and you will always find something that has a significant difference, even if it's trivial, and often just noise in the data set. This is a common, and deceptive, tactic used in many studies these days because the researchers don't want to run a study where they found nothing of interest.
large, consistent and dose dependent
@@defeqel6537 dose dependency in human placebo trials is not a factor in determining causative outcomes. Every body is different and receives the same dose of the substance/placebo. Impossible to determine dose dependency and it isn't important either. This isn't a drug that's being tested, and all diets are variable. Dose response curves to food do not exist because of individual variability
Awesome video! Just to clarify, what do you mean by "total area under the curve"? Thx!
Greate video great educational content i wish more poeple start to think critically and dont cherry pick studies and conclusions that they want to hear
Layne sure does love his diet sodas
Hello Layne
The heading is the hypothesis, reading the paper provides the conclusion.
Ok Jeez, I subscribed after that begging part.
for the dang alg!!! biolaynee for lifeee.
love it... FOR THE ALGORITHM
good
it makes sense the 15 minute timepoint was different, artificial sweeteners linger compared to sucrose - also what gives diet products that characteristic aftertaste. It really is not a problem in any way.
My thoughts and prayers go out to the algorithm.
Biolayne has a growth mindset. Very nice
You are not wrong about Dr. Layne. If you look through the list of authors and their previous work, not a single microbiologist or someone with extensive experience with studying microbiome. Calling a simple asymptomatic change in microbiome composition "dysmicrobiosis" is a stretch. These changes happen even with menstrual cycle, season of the year etc. So many possible confounders. I would just state that there was a significant difference between the groups at the end of the experiment and discuss possible causing factors, but wouldn't call it a dysmicrobiosis.
Thx
Subscribed and comment for the algorithm.
Thanks, I don't feel so guilty now having had Sucralose-sweetened cheese cakes all those weekends.
for the rhythm!!!!
The title of this video should say sucralose instead of artificial sweeteners because there is a whole lot of different artificial sweeteners
Any research on natural sweeteners?
0:43 Real science described in one sentence.
Thank you for continuing to rescue data from being tortured.
I love that you’re willing to dive into the studies, even if they might prove you wrong! This one didn’t 🤪lol.
Literally subbed 3 times now - CZcams keeps unsubbing me :(
Typical
I wonder how much any of this matters if you’re also eating plenty of fiber.
I appreciate your focus and emphasis on sucralose rather than the entire group of artificial sweeteners. There are far too many chemical differences to group them together.
Question to you, is there work being done with other A.S. to determine if they have a negative impact on insulin resistance?
Also, comment for the algorithm boost!
Not sick of artificial sweetener content! For the algorithm!
Do you know if there are any studies on artificial sweeteners and their effects on cortisol, LH or FSH?
I love lamp
Artificial sweeteners help keep me from consuming actual sugar. As someone with insulin resistance, SUGAR messes my body up. Artificial sweeteners help keep me from binging on said sugar.
Anyway, when I have different artificial sweeteners that I don't have often, such as allulose, it definitely causes gut issues b/c my body isn't used to ingesting it. Just like when I suddenly eat sugar again after not having it for a while, it gives me a stomach ache, headache and overall makes me feel ill.
its the same like i now smoke e-cigarettes so i dont smoke nikotin... you just fool yourself... sweeteners are in no way healthy or usefull, they are maybe a good solution for weak people that look for excuses...
Wow I have herd people talk and talk about how artificial sweets destroy the gut biome One CZcamsr said that the pink pack sugar was like an atomic bomb to your gut biome. I have believed for years now that that stuff is poison. Also recently subscribed to your channel and have learned a lot . Keep up the good work.
Once you cut out sugar completely you recalibrate your sensitivity to sweetness. Fruit is like a lolly to me now.
So this is one of those studies that was fishing for any post hoc factor that had a significant difference. I can't remember the name of this but if you have a small sample size and the number of factors you examine is greater than your sample size you will always find something that is significant.
p hacking
@@biolayne1 Thanks!
What about aspartame and acesulfam-k ?
For the information and for the algorithm ; )
I’m curious what studies will say if they repeated this experiment with other forms of artificial sweeteners
would you say then also Erythritol is generally safe too?
5. Conclusions
This clinical trial demonstrates, for the first time, that consumption of 48 mg of sucralose every day for ten weeks induces gut dysbiosis by increasing Blautia coccoides and decreasing Lactobacillus acidophilus in healthy non-insulin-resistant young adults. As far as we know, this is one of the first long-term clinical trials showing that sucralose amounts, far lower than the suggested ADI, alter the balance of the gut microbiome, while also being associated with significant elevations in AUCG and serum insulin in response to glucose loads.
what if you regularly eat yogurt and kimchi. would additional lactobacillus acidophilus help your microbiome?
Since sucralose is mixed with other ingredients in a packet of Splenda, how many packets would it take to consume 48 grams of sucralose?
@@bobbyadkins6983 A packet of Splenda has 12mg of Sucralose, so 4 packets is equal to 48mg.
@@catea2551 If I took ten kids and stuck them in a room and only fed them macaroni and cheese laced with lead paint chips, would adding more kids to the room make the lead paint chips less dangerous?
@@bobbyadkins6983 4 packets of Splenda would equate to 48mg of sucralose. A very common daily amount.
Calories in vs calories out
I like the fact that you hawk your sups laced with ace k and Sucralose. And are 50% transparent about it.. Knowing very well that the use of them is to get people neurologically hooked on the product. Not just to “taste” better. “yes we use them, and yes we know why we actually use them. Less calories. As well as gaining repeat consumption [high chance of neurological dependence].” Food and sup hawkers never ever say the quiet part out loud. 🤣
Since finding laynes content in Jan, I no longer obsess and purchase crazy expensive/fancy ‘pure stevia’ products …. The other sweeteners were paramount in helping me loose 2.5 stone the other year after all!
2.5 stone?
Do you have a opinion on knees over toes guy bulletproof your back know you worked with McGill think it would be a great topic for you to break down. Herniated a disk 2 years ago ok now but can still irritate do McGill big 3 every day farmer Carie’s and walk a lot. Thx✌️
whatever it does its a hell of a lot less than the equivalent level of sugar
my homa test results;
homa ir 0.6
homa b 44
Should I continue high carb or change to low carb?
This is gotta be one of the worst cases of confirmation bias I’ve ever seen
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