I Was WRONG About Artificial Sweeteners? | Educational Video | Biolayne

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  • čas přidán 23. 08. 2022
  • Subscribe to REPS:
    biolayne.com/reps/
    Study Discussed:
    www.cell.com/cell/fulltext/S0...
    Non-Nutritive Sweeteners decrease body weight & improve glycemic control long term:
    pubmed.ncbi.nlm.nih.gov/35285...
    pubmed.ncbi.nlm.nih.gov/32216...
    pubmed.ncbi.nlm.nih.gov/24944...
    pubmed.ncbi.nlm.nih.gov/33168...
    pubmed.ncbi.nlm.nih.gov/29760...
    pubmed.ncbi.nlm.nih.gov/30602...
    Butyrate improves glycemic control: pubmed.ncbi.nlm.nih.gov/35623...
    Propionate prevents weight gain in obese adults: pubmed.ncbi.nlm.nih.gov/25500...
    Propionate increases energy expenditure & fat oxidation: pubmed.ncbi.nlm.nih.gov/29134...
    B. Fragilis decreases intestinal inflammation: pubmed.ncbi.nlm.nih.gov/21664...
    Streptococcus may improve T2D: pubmed.ncbi.nlm.nih.gov/31223...
    / laynenorton
    / biolayne
    / biolayne

Komentáře • 844

  • @nyguy5370
    @nyguy5370 Před rokem +698

    As a PhD scientist who makes a living doing medical research, and has more than a passing interest in this subject because I am a type 2 diabetic, and I have worn a CGM, I think this study established nothing more than that by changing ones diet, you alter the gut microbiome. Layne is dead on that this is hard to interpret. It could be good, it could be bad, it could be neutral. There is no data in the study that supports am overall negative effect of NNS, and the authors even caution in the manuscript that based on this data one should NOT abandon NNS for sugar. Water will always be the best beverage, but I think for 100% of humans, drinking beverages sweetened with NNS’ is far better than drinking something sweetened with sugar. Having published in Cell myself, I agree with Layne that as high a profile journal as it is, there is plenty of great research and plenty of crap in the journal as well. This study is well designed on the whole, but its publication in Cell will cause its impact to be far greater than the dataset presented justify, in my opinion. Finally - an anecdotal finding with an N of 1; my pretty healthy 80 year old Mother drank TAB for decades and still uses Sweet-N-low in her multiple cups of coffee everyday. So if you are one of those people who insists that NNS’ are bad, you will likely cite this study, probably incorrectly, as supporting your point of view. If you think NNS is good, this paper does little to change your mind.

    • @asherrfacee
      @asherrfacee Před rokem +16

      Appreciate the information. Do you know if there any correlation between artificial sweeteners and memory loss or cognitive decline?

    • @huddwah
      @huddwah Před rokem +35

      thanks that saved me from wasting 10 mins... (I have to watch his videos at 2x speed... and wish he had more humility)

    • @marcdaniels9079
      @marcdaniels9079 Před rokem +60

      @@huddwah Why ? Do you think all the charlatans and influencers are humble?
      He is debunking BS and more power to him.
      If you can’t be bothered to watch the extremely high quality videos why not unsubscribe? I am sure he will
      live with it. 😉

    • @BOSSDONMAN
      @BOSSDONMAN Před rokem +4

      It's like those headlines that say "X activity causes changes in the brain."
      Like okay, what is its significance? Does it have any potential predictable capability or insight of observing as such?

    • @nomnomnooma
      @nomnomnooma Před rokem +11

      @@marcdaniels9079 lol at your gate keeping

  • @AZ_TONY
    @AZ_TONY Před rokem +10

    This is the longest "I don't know" response I've ever witnessed

    • @plaidchuck
      @plaidchuck Před rokem +6

      Welcome to science.

    • @gwgez
      @gwgez Před 4 dny

      Thank you! You helped save me the time of watching this particular video. Still a fan of the channel.

  • @ChristopherMurtagh
    @ChristopherMurtagh Před rokem +245

    I love how Layne just sticks to the data, regardless of whether it matches his expectation bias and delivers the content with no bullshit. If only the media would report on scientific studies this way.

    • @A_Turner
      @A_Turner Před rokem +6

      Layne is such a gift to the fitness industry, begging for a collab between him and Mike Isratel

    • @francescafrancesca9872
      @francescafrancesca9872 Před rokem +3

      That's very true!! Imagine if he was a news journalist....he'd be hunted down

  • @coach_chonko
    @coach_chonko Před rokem +22

    Every time there is unsupervised work being done by subjects, it turns out that most subjects lie, make up data, forget to do it... In one study I set up, we asked patients if they lied/made-up data/forgot at the end of the data collection, pretending that it wouldn't matter if they did and behaving like bros. More than half did the measurements wrong and made up the data to cover their mistakes. That is huge.

    • @dama301
      @dama301 Před rokem +11

      Maybe you're making this study up? 🤔

    • @Francisco-Danconia
      @Francisco-Danconia Před rokem

      I would believe that entirely. Humans are lazy

  • @jamesk4452
    @jamesk4452 Před rokem +254

    Coke zero is the peak achievement of the scientific community. FTA.

    • @DAatDA
      @DAatDA Před rokem +35

      They should've won a nobel prize

    • @jessiel7694
      @jessiel7694 Před rokem +1

      💯😆😂

    • @TheMastermind729
      @TheMastermind729 Před rokem +25

      That stuff is nuts, can’t tell the difference

    • @TheCCBoi
      @TheCCBoi Před rokem +21

      No, diet mountain dew is

    • @jamesk4452
      @jamesk4452 Před rokem +4

      @@TheCCBoi I haven't drank mt dew in 15+ years. I'll give it a shot though.

  • @CNS1908
    @CNS1908 Před 11 měsíci +4

    Found you on the Huberman podcast and so happy I did. I love the way you think and explain. Appreciate it.

  • @jumproper8990
    @jumproper8990 Před rokem +6

    thanks for breaking down the study, and your criticism was very interesting and which teaches us a lot about the limitation of individual studies

  • @ptortland
    @ptortland Před rokem +62

    As a sports medicine physician, I LOVE these deep dives into the research! I also deeply appreciate Layne’s oft-repeated mantras:
    1) Facts don’t care about your feelings
    2) That which can be asserted without evidence can be dismissed without evidence.

    • @jsmith5764
      @jsmith5764 Před rokem

      Can you explain what you take "that which can be assertive evidence can be dismissed without evidence", to mean? Is that another way of not reasoning about the assertion? To me when I think on it it isn't saying much or wanting interesting. Thoughts? Thanks

    • @Counter-Intuitive
      @Counter-Intuitive Před rokem +2

      On another note #1 and 2 are perfect defeaters for all religions

    • @bobbobson4030
      @bobbobson4030 Před rokem +6

      @@jsmith5764 Me: "The world is run by pink unicorns" (assertion)
      You: ”What evidence do you have for this claim?"
      Me: "Nothing, but I promise they exist!" (No evidence)
      You: "Please stop wasting my time"
      You haven’t disproven that pink unicorns run the world. But on the other hand these unicorns could also green, purple…maybe they are actually tortoises…or any other one of an infinite list of possible claims. How do we know which is correct?
      It’s pointless to waste time trying to disprove a claim with no evidence since there are infinite such claims

    • @Counter-Intuitive
      @Counter-Intuitive Před rokem

      @Zog Bot You're correct, arguments like that only convert intelligent people to the default agnostic position.

    • @peachcobbler641
      @peachcobbler641 Před rokem

      @Zog Bot you never won an arguement In your entire life

  • @Mir-gw6kj
    @Mir-gw6kj Před rokem +70

    As someone doing their PhD in microbiome research, I can say for sure that increases in SCFA-producing bacteria is almost always considered a plus. SCFAs, especially butyrate, are extremely beneficial when it comes to intestinal barrier integrity and reduced inflammatory tone.

    • @ExsoLam
      @ExsoLam Před rokem +8

      I wish more folks would bring SCFAs up when fiber is discussed. I only have a BSc in microbiology and only took one course on host-associated microbiomes, but it made a lot stuff click into place.
      Fiber isn't calorically neutral, we can yield up to 2.5 cals per gram, because of the SCFAs. An important consideration when counting calories. And fiber being super good for you doesn't make much sense if you think of it as just controlling the consistency of stool. Makes people underappreciate the benefits of fiber (and fruits and vegetables generally).
      And with the gut being such a major immune hub and with the gut-brain axis being recognized as more and more important, seeing fiber as NOT just this passive bulk is super important imo.

    • @maravillin
      @maravillin Před rokem

      Do artificial sweeteners increase SCFA producing bacteria?

    • @Mir-gw6kj
      @Mir-gw6kj Před rokem +11

      @@maravillin based on the video, it seems like they increase levels of SCFAs (butyrate, propionate, valerate) as well as the abundance of SCFA producing bacteria, although the metabolites were correlated with negative outcomes, which is odd. Other non- nutritives like sugar alcohols may also have some prebiotic effect, as does stevia

    • @BigDees19
      @BigDees19 Před rokem

      ​@@ExsoLam so your saying that all fiber on a gram bases does have calories at least 2.5 per gram soluble or not soluble ? Just wondering cus I always heard fiber doesn't get a ostef as energy so it's basically 0 calories or net calories

  • @meredithbrooks2858
    @meredithbrooks2858 Před rokem +7

    As a person who never liked the taste of diet soda, eating or drinking anything with non nutritive sweetners was a shock to my system - I'm glad I watched this video and have a better understanding of what is happening - thanks Layne for making published research understandable

  • @bastipear2864
    @bastipear2864 Před rokem +20

    Dude, I am hooked to your channel! I can't wait till you tell me one day if sweeteners are unhealthy or not. Till then, I will blast my system with this stuff

  • @SpartanWolf222
    @SpartanWolf222 Před rokem +111

    As someone who has lost almost 60 lbs within the past 5 months, I can pretty much thank artificial sweeteners for helping me keep myself satisfied with less/zero calorie alternatives (both more natural options like monkfruit and artificial ones like Splenda.) If I had to point to one culprit that made me go up to 300 lbs over the past two years, I think it would have to be the amount of sweet tea I drank on a daily basis.
    I know this is anecdotal and I can't say definitively that it was as simple as that alone; however, I know I used to drank 30 - 40 oz of sweet tea on a daily basis, and that is somewhere around 320 - 450 extra calories every day that I never considered to be an issue. Once I stopped drinking that stuff and made other low calorie switches to my normal meals--and I even curbed my tea intake to just one 20 - 25 oz just to help with my teeth staining--my weight has been melting off without too much hassle on top of increasing my weekly exercise and portion control.

    • @charlesdean640
      @charlesdean640 Před rokem +8

      That's like a crack addict switching to powder cocaine and thinking they kicked their habit

    • @butsirrr
      @butsirrr Před rokem +19

      @@charlesdean640 You seem to know a lot about drugs... hmmm

    • @03blaird
      @03blaird Před rokem +6

      @@charlesdean640 EXACTLY. these people are quick to blame natural sugar for their weight gain instead of I dunno... Maybe not stuffing their faces with garbage in the first place?!? If you're 300 pounds of fat trust me switching to an artificial sweetener won't solve the other fundamental problems that made you gain that much weight in the first place!

    • @asyetundetermined
      @asyetundetermined Před rokem +22

      @@charlesdean640 It’s not really anything like that at all. GTFOH if you’re actually afraid of a packet of Splenda. Get real dude. Let’s not let perfect be the enemy of good.

    • @charlesdean640
      @charlesdean640 Před rokem +2

      @@asyetundetermined did I say I don't consume sugar or Splenda? No I said he kicked one habit for another. Didn't say anything about myself.

  • @janenuss6
    @janenuss6 Před rokem +1

    Thank you for the information and summarizing it in such a straightforward way!!! 🙏🏻

  • @Grim_trades
    @Grim_trades Před rokem +1

    Really good talking points! That stress response explanation makes major sense

  • @pablov1323
    @pablov1323 Před rokem

    This study also got my attention, Happy to hear your analysis!

  • @midnightblack07
    @midnightblack07 Před 11 měsíci +2

    Thank you so much for this video and for breaking down the facts in such a simple and unbiased way! I've seen so many fear-mongering videos regarding non-nutritive sweeteners in the last few days (especially following the WHO's recent recommendation), so this was incredibly refreshing.

  • @robertkraychik1884
    @robertkraychik1884 Před rokem +1

    thanks, layne. interesting breakdown of the strengths and potential weaknesses of the study.

  • @alankuo2317
    @alankuo2317 Před rokem +5

    I feel like whenever I see the term gut micro biome, I think of how big and vast the ocean on planet earth is, and how little we know, in depth, about all the creatures that may exist in it

  • @MindPumpShow
    @MindPumpShow Před rokem +3

    Great breakdown layne

  • @ThePowerMoves
    @ThePowerMoves Před rokem +8

    One of the few voices of reason in nutrition.
    Thanks man

  • @0s0n3gr0
    @0s0n3gr0 Před 11 měsíci

    Whenever I need clarity on these matters I turn to use @biolayne. You cut through the bullshit and simplify the complex in doses the layman can understand. You also show how the vaguely understood scientific method is actually applied IRL and give it depth and context. Thank you sir.

  • @Pinkorchid72
    @Pinkorchid72 Před rokem +6

    I really love that you break down the science in a way that the average non-science person can understand. I appreciate your perspective and your opinion. Always entertaining and well informed. I feel like after watching your videos that I learn something new all the time. Thanks for all your hard work!

  • @Ryan_DeWitt
    @Ryan_DeWitt Před rokem +232

    I have been taking in enough artificial sweetener to satisfy an elephant on a daily basis for 17 years now. I am lucky to be alive.

  • @Anusdeur
    @Anusdeur Před rokem +5

    Again a great nuanced non-biased analysis. This is so valuable. Thanks Biolayne, for always keeping it real💪🏼💪🏼💪🏼

  • @ibperson7765
    @ibperson7765 Před rokem +5

    Note on DURATION:
    1. If something statistically significantly affects you in two weeks, it does.
    2. If not, that *could be* because it’s too short.

  • @croxmcjames8038
    @croxmcjames8038 Před rokem

    Always great content from you! Thank you

  • @kimdavis7812
    @kimdavis7812 Před rokem +1

    Sound knowledge Layne !! Thank you

  • @jofortin22
    @jofortin22 Před rokem +1

    Great explanation Dr. Norton!👏🙂

  • @Sardy540
    @Sardy540 Před rokem

    Awesome summary and analysis mate! Cheers from Australia!

  • @ObliviouslyLucid
    @ObliviouslyLucid Před rokem +1

    Well done- Thank you for the analysis.

  • @mcfarvo
    @mcfarvo Před rokem +1

    A fair summary, critique, and conclusion

  • @soaringeagle5227
    @soaringeagle5227 Před rokem

    Great video. Thanks Layne!

  • @neilrasmussen2063
    @neilrasmussen2063 Před rokem +5

    Not sure if I missed some fact, but it seems like the most emphasis was on the participants potential bias against artificial sweeteners. However around 7:26 in it was stated aspartame didn't affect blood glucose like the sucralose and saccharin, which proves that is not the case.

  • @ColinDeWaay
    @ColinDeWaay Před rokem

    What a freaking phenomenal breakdown great job dude, killer info!

    • @priscillabahaw5673
      @priscillabahaw5673 Před rokem

      Waw colon dewaay won a prize from Layne . How cool

    • @ColinDeWaay
      @ColinDeWaay Před rokem +1

      @@priscillabahaw5673 😂🤦🏻‍♂️ dang spam bots

  • @clubmogambo3214
    @clubmogambo3214 Před rokem +29

    Been using liquid Splenda for several years and more recently liquid Splenda monk fruit. Never had any problems with yearning for food containing actual sugar as so many claim results from using no-sugar sweeteners. Have lost more than 60 lbs in conjunction with keto and IF. And my last blood and urine test results were the best in a couple of decades. So I'm fine with taking the opinion that no-sugar sweeteners have been a blessing for me.

    • @phil4986
      @phil4986 Před rokem

      if drinking regular water without the spenda gets uncomfortable, you should get off the splenda. splenda addiction will attack the stomach and intestines. it will take two months for your insides to repair themselves from splenda induced damage.

    • @clubmogambo3214
      @clubmogambo3214 Před rokem +4

      @@phil4986 Where in my post did I say I was uncomfortable with drinking water? I'll wager a ton of internet money that I drink a lot more water than you on any given day. I only drink Splenda-infused drinks, almost always iced tea, when I'm having a meal. And even then there are times when I drink water only. So why you stated what you did is quite perplexing.

    • @louisaklimentos7583
      @louisaklimentos7583 Před rokem +3

      I lost weight without artificial sweeteners I drink purified water and soft drinks I find too sweet even if they have artificial sweeteners and no sugar . People who have poor digestion should avoid beverages with artificial sweeteners because our digestive system is styled to digest real foods and nothing artificial.

    • @clubmogambo3214
      @clubmogambo3214 Před rokem +4

      @@louisaklimentos7583 Not an issue for me, but if it is for you, then by all means avoid them.

    • @MArixor100
      @MArixor100 Před rokem +8

      @@louisaklimentos7583 Ever heard of lactose intolerance? not artificial yet it still irritates the digestive system IF u are sensitive yet people still consume dairy on a daily basis.

  • @tyreecenewton3194
    @tyreecenewton3194 Před rokem

    Thank you for helping me understand, great channel !

  • @danielangst7948
    @danielangst7948 Před rokem

    As always very well done 💪🏼

  • @Nobody-fr3wz
    @Nobody-fr3wz Před rokem

    Love your content. Much love from London

  • @allisonfalin8854
    @allisonfalin8854 Před rokem +7

    Something I have learned wearing a CGM is that if you do not know precisely when to insert the cannula (can't do it when you are dropping sugar or it will be off by a good bit), calibration techniques etc, then the data from it is useless. It was an interesting study to read for sure, but I did wonder how they managed to do some of the data as you spoke to. I will continue with my occasional Coke Zero and motor on. Thanks for the interpretation.

  • @charliehaskell1926
    @charliehaskell1926 Před rokem +4

    It makes logical sense that it would take the body a bit to adapt to something new. It’s actually really cool to see a study on a population where they are trying something brand new to their body chemistry. Shame about the implementation. Fascinating study in any case.

  • @chewher4171
    @chewher4171 Před rokem

    Very informative and insightful. Thanks man.

  • @ThomasAT86
    @ThomasAT86 Před rokem +2

    Always interesting to hear all the different things that can alter an outcome, influence a study etc!

  • @Editor_Steve
    @Editor_Steve Před rokem +82

    18:55 most important part of this video. The study is legit. The interpretation by people with out this sort of critical thinking (aka the media) is what will be dangerous.

    • @EvsPersonal
      @EvsPersonal Před rokem +5

      Well said. Unfortunately, this is the case with MANY media vs. studies with nutrition

    • @fl676
      @fl676 Před rokem +1

      👍🏻

    • @SubZero-kb1ir
      @SubZero-kb1ir Před rokem +1

      Hey, it's Editor Steve. Hello Editor Steve. Fan of your work.

    • @Gladiator1972
      @Gladiator1972 Před rokem +6

      The placibo effect reminds me of an experiment a college professor did with his class. One day he told them he was going to break the rules and let them drink beer in class. What the students didn't know was they were drinking non-alcoholic beer (O'Douls). After a little while of "drinking", the student's voices became louder and some started acting buzzed.

    • @Counter-Intuitive
      @Counter-Intuitive Před rokem +1

      The msm is just interested click bait. I remember when they were attacking Biden for pulling out of Afghanistan when in reality it was a positive thing.

  • @yesiamsharon
    @yesiamsharon Před rokem

    Thanks for the review and explanation.

  • @320csan
    @320csan Před rokem +12

    I wonder if the researchers tracked dietary intake outside of the addition of non-nutritive sweeteners. Maybe the groups that were assigned to non-nutritive sweeteners ate differently as a result of knowing they were eating something they identify as "bad", because like mentioned, it's hard to blind here. Just adding my thoughts! Either way, great to know there is finally a human study!

    • @jimmymuthami7130
      @jimmymuthami7130 Před 7 měsíci

      This has always been my issue with all these studies. They will say meat is bad because a certain group was eating this amount of meat and another wasn't eating. They won't say what else those guys were eating.

    • @Ozzy1984_
      @Ozzy1984_ Před 5 měsíci

      ​@jimmymuthami7130 in terms of meat and sugar, there have been plenty of studies where the participants are provided all of their food, which removes that risk. The data is pretty solid that meat and sugar are fine provided they dknt create a calorie surplus and you gain a lot of weight. It's pretty much as simple as calories in. Calories out.

  • @lrn_news9171
    @lrn_news9171 Před 4 měsíci +1

    Artificial sweeteners haven't been around long enough to know how bad they are or even how safe. It's been consumed at a significant rate since the mid 2000s

  • @Dominasty
    @Dominasty Před rokem +1

    I've been reading your work, Layne, since before you entered into your Ph.D. program.
    As always, enjoy your content. From your MD days to the CZcams days. Love it.

  • @asirbbrisa
    @asirbbrisa Před rokem

    Power of placebo! Great call out! Thank you!

  • @BornToRun.
    @BornToRun. Před rokem +3

    Fascinating! Can’t give up my Dew Zero.

    • @phil4986
      @phil4986 Před rokem

      Of course you can't ....the soda company put a manmade poison in it to addict you to it. They get rich, it makes you sick, the pharma companies get rich ,you die.
      Everyone wins but you and the family watching you die.

  • @calloforestis3126
    @calloforestis3126 Před rokem +4

    Thank you layne👍, amazing video you make studies so easy to understand

  • @avivbrina
    @avivbrina Před 2 měsíci

    Hey Layne, it’s great to finally see someone address this study and you make some great points.
    There is one minor thing I think you misunderstood about the study: the participants were screened for 6 months of nonconsumption, not ever in their lives. From the study: “We excluded participants who consumed any quantity of NNS-containing foods or beverages in the six months prior to the trial initiation”. This makes the supposition that the participants had unusually negative opinions on NNS far less likely.

  • @sorkeror
    @sorkeror Před rokem +3

    Life is turning out to be pretty dangerous, there are literally billions of things that can harm and kill you

  • @steverino474
    @steverino474 Před rokem +1

    When ever i start falling for woo...i rewatch Laynes videos.

  • @terrencemartin2621
    @terrencemartin2621 Před rokem

    Excellent video, learned a lot but sorry I am already subscribed to REPS!

  • @asiastormy8728
    @asiastormy8728 Před rokem +25

    I am wondering ultimately, with that study even if there is an rise in insulin or glucose, how much of an adverse effect it has on say someone with Diabetes 2? If the raise level is negligible compared to what sugar or carbs does, I am willing to keep using artificial sugar.

    • @gamer4ever838
      @gamer4ever838 Před rokem +4

      Its safe. Why? Because products contain maybe 100 mg aspartame. MG. NOT GRAMS.
      its so little your body wont even notice

    • @xMCxVSxARBITERx
      @xMCxVSxARBITERx Před rokem +7

      @@gamer4ever838
      100mg can be a lot...or nothing, depends on how toxic it is really.

    • @xMCxVSxARBITERx
      @xMCxVSxARBITERx Před rokem +7

      Diabetes 2 is mostly caused by carrying too much bodyfat... So no matter if there is a rise in insulin or not (short term), it is quite irrelevant, as the best way to combat D2 for most people is losing weight (calorie defecit, not sugar/insulin deficit lol).
      It can of course be different for those few who are diabetic without being overweight...

    • @gamer4ever838
      @gamer4ever838 Před rokem +3

      @@xMCxVSxARBITERx thank you. You are one of the few people that understand CICO

    • @xMCxVSxARBITERx
      @xMCxVSxARBITERx Před rokem

      @@gamer4ever838
      Was that sarcasm or was you serious? 😊

  • @juhamartikainen3050
    @juhamartikainen3050 Před 10 měsíci

    This was just the thing I was interested to know.

  • @Doormat00
    @Doormat00 Před rokem +3

    Would be interesting if you also mentioned who funded the studies.

  • @forthelulz8085
    @forthelulz8085 Před rokem +3

    I drink a diet soda for lunch 5 days a week and I can tell you, for me, it keeps me from giving into my sugar cravings. The cravings are simply dulled because my brain thinks it got the sugar already.

  • @UbzUnclemax
    @UbzUnclemax Před rokem +1

    I wonder if he would be so soft on the researchers if they had done a weight loss study with controlling caloric and protein intake, but at the end of 2 weeks letting the participants measure the primary outcome 'bodyweight' at home ...

  • @robertbaillie2948
    @robertbaillie2948 Před rokem +11

    30 years using aspartame, 65 now. Feel great fit as I have ever been.

    • @moa3821
      @moa3821 Před rokem +3

      Weve had saccharin for 140 years now. My mom said it was popular in Nigeria in the 60-70s. We should have enough safety data at this point

    • @funnygaming2672
      @funnygaming2672 Před rokem +3

      aspartame is the only sweetener that give me heart palpitation ...I prefer stevia and the other option anything but aspartame!

    • @phil4986
      @phil4986 Před rokem

      @@funnygaming2672 aspartame is poison.
      Mr.Baillie will find out soon enough but that is his choice.

  • @zadinal
    @zadinal Před rokem +11

    I would like to point out that prior to five years ago I had never consumed artificial sweeteners. Not because I thought they were bad I just liked regular sugar and preferred to make most of my own foods so it is completely within a realm of possibility that the participants just didn't consume them for non ideological reasons.
    Sounds really interesting, I'm going to go check out the article.

  • @mightywind7595
    @mightywind7595 Před rokem +9

    I use stevia daily and only have a little sugar once or twice a week. I use a teaspoon in my coffee and 1\4 teaspoon in my tea at bedtime. My mom is sure it will kill me because of some studies. I assured her that I would have to consume a bag or more of stevia a day to hurt me. It keeps me away from sugar and to me it’s a good trade off.

    • @RogueCylon
      @RogueCylon Před rokem

      Have you tried monkfruit extract?😊

    • @phil4986
      @phil4986 Před rokem

      just stay away from aspartame and splenda/sucrolose.
      Both are man made chemical poisons in foods only because they are cheap and highly addictive.

    • @SevenCostanza
      @SevenCostanza Před 11 měsíci +1

      Look on the back. You're actually consuming 99% erythritol

    • @edgewound
      @edgewound Před 4 měsíci

      even Stevia triggers an insulin response. The trigger is the sweetness on the tongue that triggers the brain to release insulin preparing for the metabolism of sugar. Not good for the pancreas or the liver. Quit added sweetness and let your brain adapt to not needing it. Coffee is better for you unsweetened.

  • @kostas9094
    @kostas9094 Před rokem +3

    Interesting study, thanks for sharing.
    Typically the microbiome tends to return to normal within a month after moderate diet changes. Especially as NNSs are prebiotics I would expect a permanent shift in the microbiome to occur after at least 6 months considering consistent and high use.
    It would be more interesting to see longitudinal studies in people consuming NNSs. Perhaps they could stratify into low-medium-high users.
    Also I would be interested to see use of NNSs within people with gut related conditions such as IBS, IBD, etc.
    How does the microbiome change then and what are the implications. How could we reverse the microbiome to “normal”?

    • @batman-sr2px
      @batman-sr2px Před rokem

      what about supplementing with probiotics. If someone needs to live on diet coke or a medication that reduces microbiome for whatever reason, do probiotics actually help balance?

  • @JimGrass62
    @JimGrass62 Před rokem +1

    My Doctor recommended you.... sure glad he did

  • @ddavidjeremy
    @ddavidjeremy Před rokem +1

    I may have to watch again but did you ever mention what the study said or was that a prerequisite.

  • @Pilarfitvegas
    @Pilarfitvegas Před rokem

    Loved this!!

  • @burtnation1357
    @burtnation1357 Před rokem

    I appreciate this review and discussing there effects on the micriobiome and the unknown

  • @osamatarek7862
    @osamatarek7862 Před rokem +1

    I wonder if i will ever be able to discuss research like layne does , however I’ll keep trying

  • @Ali-kf5bd
    @Ali-kf5bd Před rokem +3

    I used to have basically a diet soda addiction and I don't think drinking a 2 litre of soda in a day is a good idea even if it is low calorie BUT these days I will have a single serving of diet soda a couple of times a week and I'm pretty confident that it's not causing me any issues. I'm in pretty good physical health and while I'm still a tiny bit overweight I used to be bordering on obese and I've been able to keep off 30 pounds for 2 years while drinking diet soda here and there. Of course that's just anecdotal but for me at least it doesn't seem to be a problem,especially compared to all the sugary treats I used to overindulge on.

    • @phil4986
      @phil4986 Před rokem

      this young woman had a massive reaction to aspartame and lost nine pounds in four days when she got off it.
      czcams.com/video/aAPJMMMGCOY/video.html

  • @CaptainBerz
    @CaptainBerz Před rokem +2

    Yea, people get caught up in this perfection complex. For someone who is drinking 2 sodas, regular, everyday and they switch to say one Celcius (Sucralose) a day, that would be a step in the right direction. While not perfect, though, it is better.

  • @romac5362
    @romac5362 Před rokem +10

    You rule bro. Big fan here all the way from New Zealand..
    Often share and post your content.. especially the bro science, whatever zealot bullshit..

  • @ExsoLam
    @ExsoLam Před rokem +3

    The increase in SCFAs suggests to me that the non-nutritive sweeteners are being metabolized by gut microbes similarly to fiber.

    • @batman-sr2px
      @batman-sr2px Před rokem

      so is that bad for the microbes? What is the result of this?

    • @ExsoLam
      @ExsoLam Před rokem

      @@batman-sr2px It's good for some microbes, the ones who can metabolize the non-nutritive sweeteners. Bad for ones that can't, and who need simple sugars. That would lead to the change in composition.
      The SCFAs they produce are just metabolic waste, like CO2 for us. It doesn't hurt or harm the microbes, but it SUPER helps us. SCFAs are incredibly good for the gut.

  • @disinformationworld9378
    @disinformationworld9378 Před rokem +2

    I would look into all health effects. Corporations also have funded studies so that their products are promoted in a favorable light.
    So one study is not enough.

  • @NapoleonSupreme
    @NapoleonSupreme Před rokem +2

    Hey Layne, I use pure sucralose powder, that has no bulking agent in it. Is it better than regular Splenda, since bulking agents still have some calories?

    • @wyzasukitan
      @wyzasukitan Před rokem

      Same here, I would like to know! When I’m not using monkfruit or erithrytol (no bulking agents), I use liquid Splenda because it has no maltodextrin. I don’t use Splenda packets specifically because of the maltodextrin

    • @phil4986
      @phil4986 Před rokem

      Sucrolose and Splenda are the same thing.
      It is a man made chemical that is poisonous to your stomach and intestines.
      Aspartame is actually a stronger poison.
      Aspartame causes edema. brain issues and blood clots.
      You would be better using stevia or monk fruit but it depends on how those are processed.

  • @Joseph1NJ
    @Joseph1NJ Před rokem +3

    "Saccharin and sucralose impair glucose tolerance in healthy adults." In just two weeks? Wow!

    • @phil4986
      @phil4986 Před rokem +1

      Aspartame is just as bad.
      This crap is poison.

  • @scotter
    @scotter Před rokem +1

    Apologies if I missed this and maybe this was not something you considered relevant to the topic: What about past evidence pointing to aspartame, et al, being neurotoxic?

  • @theylikollikasecial
    @theylikollikasecial Před rokem

    Am I the only one who thinks there might be something wrong the microphone used to record or sound recording settings? The sound comes as excessively "sharp" and really tough for the ears at least for me; even on low volume.

  • @86Dynamix
    @86Dynamix Před rokem +7

    This is another great video from Layne. However, I think that something important is not being addressed here. These test subjects started taking sweetener, but what did they replace with sweetener? If these people were comsuming lots of sugary beverages and such before the study and then started taking a sweetener instead, could that possibly mean that the lack/absence of sugar is that actual cause of the change in the gut microbiome and not the sweetener itself?

    • @benjaminchapman3924
      @benjaminchapman3924 Před rokem

      perhaps they used the food history data that they got from the participants to determine if they used NNS before and accounted for it in the results? Dont know without reading the paper itself

  • @Finvarra
    @Finvarra Před rokem +2

    Physique on point: opinion respected.

  • @johnhillescobar
    @johnhillescobar Před rokem

    Great video!!

  • @makt7448
    @makt7448 Před rokem

    What's your take on the sucralose is genotoxic study? I ask because my protein powder has sucralose and I love it :(

  • @stephanieilluzzi7355
    @stephanieilluzzi7355 Před rokem

    WOW. God bless you! I wish you were the head of the FDA. 👏👏👏👏

  • @micacam2684
    @micacam2684 Před rokem +2

    We knew all this. Didn’t t need the study. Can you imagine if people waited around for studies to declare if something is poison or not?

    • @03blaird
      @03blaird Před rokem

      Crazy right? People today will get shot in the head and say "I'm waiting for a study to tell me if excess lead to my skull is bad"

  • @alexroseman2223
    @alexroseman2223 Před rokem

    I'm a strange one. I eat a lot of sugary candy but I drink drinks with things like sucralose. And I love it. And If the sucralose laden drinks increase my sugar handling then I'm winning right?

  • @cesargutierrez8165
    @cesargutierrez8165 Před rokem

    Byolaine, can you do a video on how seasonal, household allergies affect weight loss/fat loss. I suffer from heavy allergies and I take Claritin daily, Flonase on and off, Prednisone when I get critical or pollen is high as needed, and now astepro daily. I have found that it's very hard to loose weight and my calories are pretty low and for sure on a calorie deficit, but the scale does not move as quick as when I was younger and did not suffer from allergies or take any medication to treat my allergies. I don't know what it is, if it's all the medication or inflammation that I always have. I would love for you to dive in to this issue because I know there are a lot of people that suffer from heavy allergies and it might be a reason why obese people like me struggle with weight loss. I'm at the point where I'm going to start treatment with an allergist in the next few months, but it's expensive and it takes years to desensitized my allergies. All I read is that antihistamines increase appetite, but I feel there is a lot more to this story.

  • @tpespos
    @tpespos Před rokem +1

    Does reps include the studies it talks about too?

  • @thepeddle
    @thepeddle Před rokem +2

    Even if there is an initial spike, anything in moderation will not harm anyone. People just over due it and then shit gets vilified. I have one or two cans of diet coke a day and I'm never giving that up.

  • @DomDeDom
    @DomDeDom Před rokem

    Good start, now keep going.

  • @benjones1452
    @benjones1452 Před rokem

    Great work 😮

  • @BlackJesusChrist666
    @BlackJesusChrist666 Před rokem +5

    I’ve seen a ton of friends going from sugar beverages to artificial sweeteners to just water.

    • @kristinetran7734
      @kristinetran7734 Před rokem +4

      Agreed, I think it is a process of slowly getting off the bad stuff or rather transitioning and asking ourselves, "Do I really need that? Can I do without that?" Yippee!

    • @phil4986
      @phil4986 Před rokem

      Water won't kill you.
      Aspartame and Splenda / sucrolose will.

  • @moa3821
    @moa3821 Před rokem +14

    Everyone waiting for this. should have had sweetner users In a seperate group.
    Really weird that aspartame wouldn't cause a change

    • @phil4986
      @phil4986 Před rokem

      tells you who paid for the study.

  • @ashishtom
    @ashishtom Před rokem +3

    Should I worry about sucralose in my whey protein isolate? I take 1 scoop a day

    • @phil4986
      @phil4986 Před rokem

      find one that uses stevia or monk fruit .
      Sucrolose/Splenda and aspartame are man made chemical poisons meant to addict you to the products they are in.
      Sucrolose/Splenda attacks the stomach and intestines.
      There is no human dose that is safe.

  • @reedb5696
    @reedb5696 Před rokem +1

    What are some mechanisms which could explain the results? Sucralose increased blood glucose but didn't affect insulin or GLP-1. Could it directly impact insulin sensitivity? Could it somehow compete at GLUT receptor sites and prevent glucose uptake? Could it be increasing glucagon?

  • @DP-ye4xp
    @DP-ye4xp Před rokem +3

    Overweight people have more medical issues than thinner or in shape people. Point being that people who for years without a break live in a calorie surplus tend to have the majority of health problems across the board. Not to say there could be something wrong with sweeteners, Just saying being overweight is much worse for your health and more worry some than sweeteners in my opinion.

  • @anathardayaldar
    @anathardayaldar Před 13 dny

    Especially for diabetics, sugar substs helps to reduce carbohydrates.

  • @derekdominguez2068
    @derekdominguez2068 Před rokem +5

    I wish they’d do a long term study about the liquid forms. Without the added maltodextin or dextrose from the powdered forms. I’m sure the liquid wouldn’t spike blood glucose as much but who knows what it does the gut microbiome

  • @quentinseicappie1246
    @quentinseicappie1246 Před 5 měsíci

    I'm sorry so should I keep drinking my coffee w 2 sweetners a day..my 2yr old that I cherish so much loves a cup of tea almost daily. I put 2 Splenda w an 8 ounce tea. Is this bad long term for both of our health? Serious inquiry

  • @theoriginalbreadcrumb
    @theoriginalbreadcrumb Před rokem +1

    What about the rest of their diet? What about what other things they did? A lot of things can affect these results.

  • @AdmiralLando
    @AdmiralLando Před rokem +1

    Sure, from a weight management perspective (and from a general health perspective), NNS are obviously preferable to sugar by a large margin. I guess the question is, are unsweetened beverages preferable to artificially sweetened? In other words, is there any reason to choose the unsweetened iced tea over the Diet Coke? Or the unsweetened energy drink over the one sweetened with stevia or monkfruit? Or are they effectively the same?

    • @phil4986
      @phil4986 Před rokem

      Unsweetened iced tea does not attack your guts and has anti inflammatory effects on the body.
      Diet Coke contains aspartame which is a manmade chemical poison meant to addict you to the products it is in.
      Aspartame causes edema ,brain issues and blood clots.
      All energy drinks are a chemical soups of awfulness but stay away from Splenda/sucrolose and aspartame sweetened ones especially.
      The regular RedBull ones...not the diet ones .....seem to be ok but who the hell really knows.
      Alot of sugar though.
      Really not drinking or eating sweets unless its actual fruit seems to be the only safe sweet choice.
      But aspartame and splenda / sucrolose are man made highly addictive poisons.
      read the labels and do not buy products that contain them.

    • @user-ho4yj3df5d
      @user-ho4yj3df5d Před 7 měsíci

      @@phil4986 1. its not a posion to the human species, it can poison certain animals, but most artificial sweeteners can poison animals, but if it was a poison my mother and grand mother would be dead b y now, 2. almost all food is created with some sorts chemical compounds whether natural or lab made, 3. red bull is not okay in either form as they have been tied to deathss due to cardiac arrests, this is due to the caffiene content that is almost inhuman in terms of caffiene, if you have a heart issue, are prone to heart issues, and have no legitimate need for it (i.e. your not working a job that requires more energy.) then don't drink them, fruit is safe it depends though how much your eating, and what fruit it is, as a diabetic, I can eat certain types of fruit more than others, the sweeter it is, the bad it can be for me, even fruitarians who live on nothing but fruit alone, can induce diabetes or gain weight. sugar is more inherently and proven dangerous than artificial sweeteners you dont need a scientific study to see the damage it has historically wrought, just look at the skeletal remains of a european before the introduction of sugars, to the skeletal remains of those who had sugar readily available,

  • @eduardoboada2871
    @eduardoboada2871 Před rokem

    Did they control for caloric intake and overall diet?