The History Of Antidepressant Medications (MAOIs, TCAs, SSRIs)

Medications used in the drug therapy of depression (pharmacotherapy) have undergone several waves of innovation and evolution since their inception in the late 1950s. This video presents a little bit of history about the main phases of evolution in this process of advancement.
== Timestamps ==
Intro - 00:00
Disclaimer - 00:30
MAIOs - 02:48
Parnate - 03:00
Tyramine issues - 04:00
Tricyclic antidepressants (TCAs) - 06:15
Imipramine - 08:00
Clomipramine - 09:05
Tricyclics: disadvantages - 09:30
Lancet meta analysis - 10:11
SSRIs - 11:06
First SSRIs - 11:28
Vortioxetine - 13:00
Buproprion - 13:48
Disclaimer: this video is intended for informational purposes only and is not intended for the diagnosis or treatment of any mental health disorder.
#medication #mentalhealth #ssris
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This channel represents my small attempt to reduce the stigma surrounding depression and anxiety, particular among younger males. If you're curious about me, or want to get in touch, please feel free to do so via my personal website (danielrosehill.com) or through my main CZcams channel (danielrosehill.com/youtube).

[@ballistic_goat]

I'm pretty resistant to antidepressants, the only one that has made noticeable difference is bupropion which I still take. Ketamine treatment also helped but not as much as I hoped.
As for anxiety, a few months on a low dose of Xanax almost solved it completely, I feel it very rarely now.

[@favouritemusic8959]

That is interesting to know that the xanax helped that much with the anxiety. Could l ask you what you took daily to bring it down and at what time of the day. Many thanks from Mary.

[@KennethNordin]

You forgot moclobemide/Aurorix

[@rajjvikram]

Do you ever take alcohol?? Does alcohol affect the efficacy of anti depressants??

[@DanielSRosehill]

Hi sir! I enjoy alcohol in moderation, yes. Definitely something worth asking your doctor about for a specific med. All mine advised was that moderation is okay (a few drinks, no crazy binges, etc).

[@Lobotapro]

The amount of times you mispronounced maoi’s was hilarious

[@depressionanxiety]

I know :-(