CME - Vortioxetine: An Antidepressant. (CME): Dr Vivek Kumar

#vortioxetine #antidepressant #serotonin #modulator #serotoninmodulator
0:00 Introduction
0:21 Background
6:35 Treatment options
7:30 The definition of treatment success in depression has evolved
9:24 Barriers to achieving functional recovery
10:12 Treatment factors could lead to partial response
12:25 The Evolution of Antidepressants
16:18 Effects on glutamate and GABA (gamma amino butyric acid) release
20:06 Long term Study (52 Weeks)
24:21 Effect on Body Weight
24:54 Vortioxetine for major depressive disorder: An indirect comparison with duloxetine, escitalopram, levomilnacipran, sertraline, venlafaxine, and vilazodone, using number needed to treat, number needed to harm, and likelihood to be helped or harmed
25:42 Safety, Tolerability & Dosing Frequency
26:55 Summary
28:20 Vortioxetine Achieves Key Therapeutic Objectives