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Well explained,🎉 amazing ❤

An evil disease if there ever was one. It's a thinking virus.

This is such an evil evolutionary hellspawn

im the 300 subscriber. thank me later.

One of the most amazing videos on the subject I've seen!! Wonderful animation, thank you so much for all your work!

best

Continue please ❤

Incredible how these things operate

That's a whole lot of assumptions on the process behind techniques and mechnism behind viral infection made in one video for something of nano-sized, can only be seen under electron microscopy whose images are static, black and white, can only grow inside a host cell and indirect techniques can only be used to infer its existence which sounds rather contrary. How can one know the existence of this nano-sized virus particle if electron microscopy cannot view inside the cell? You're telling me this is all interpretation? Sounds more like speculation. How do you know these dead cells or plaque formation is resulting from viral infection and not some other confounding variable? For example, the use of anti-biotic and anti-mycotic drugs in cell culture can be poisoning cells especially the use of trypsin to break down the proteins in cells. The cell culture is outside the huamn body which means it will not receive the level of homeostasis to regulate a cells electrolyte, pH, elimination of waste product etc. and thus will die quicker outside the body. Were you taught to use controlled variables? if so, could you please show us a step by step process for the isolation and purification of a virus with the use of controlled variables? and *detail* how the controlled variables were prepared.

you are doing GOD's work bless you

We had got the dog vaccinated 9 months ago, after 9 months of getting the full course, I touched it again, so I went and got the full course done. Looks like I had to get only two waxing done Sharif

Takes one mutation to screw us all over

Given that we have such detailed information, cant we maybe hack this virus system and make it dysfunctional forever?

T-pose

Whoa! This is very informative. Imagine you are being assassinated using a small gun that shoots a very small dart that is filled with rabies (you wouldn't even notice it) then 1 week later... POOF!

If the genome of rabies viruses do contain one or more palindromic sequences, (I believe that such sequence probably exists), at least three bases upstream and downstream from the core of the palindromic sequence and one species of bacteria certainly produces a restriction enzyme that recognizes and cleaves said palindromic sequence. Then, hopefully, a novel class of antiviral therapy will be created if the target cells can be transfected with a gene encoding the restriction enzyme.

They look like the hair rolls to curl your hair.

pov you fall asleep first at the sleepover

Thank you for this detailed video, it was really helpful! I have one comment regarding the release of the new virus particles: neuraminidase is actually already actively cleaving sialic acids off of proteins in the Golgi apparatus. This way, all future plasma membrane proteins are preventively depleted of their sialic acids. This is a safer strategy, because if the bond between HA and sialic acid containing receptors were that easily disrupted by NA, it would make attachment much harder. I guess we cannot exclude the possibility that NA occasionally does disrupt the interaction between HA and sialic acid (possibly also during attachment then), but this can be dealt with by the virus by expressing 4x as much HA as NA and binding to multiple receptors simultaneously.

Great job👍👍👍👍 very helpful

we need your knowledge please continue sharing

Thank you, very useful

Thanks for this video. Very informative! Worse way to go if you get rabies.

Very underrated 😒 video. Amazing👍❤️

Great Job Irene, Andrew, John, Marianneand all the team!

great job, very helpful, keep it up

very well done! thank you

Are you there? Alive?

I really can't follow this video completely. Too scientific for me and I don't understand a lot of the terms. I'm definitely not ready for this content yet.

Great!!! thankyou so much for the information!! Now, I understand a lot. ♡♡♡

Viruses are so amazing. I am constantly in awe.

Wow, the quality on this is stunning. Expert interviews, custom animations, excellent writing and narration. You are in the right line of work, Irene!

What an amazing resource! Thank you for putting together this information with such good visuals. Keep up your good work!

I was wondering why schools never taught me this but ireland has been rabies free for a long time but I'm glad to know incase I ever travel or just in general

Pseudoscience

So are the viral messenger RNAs any different than electrical circuitry components and how they interact with the each other? My head is exploding over this stuff lol.

this is super fake . we already know you cant isolate any virus. it has to be attached to a pre-existing cell. you are fundamentally wrong

So nice

It’s more deadly than Ebola which is why I’m here 😳

Very helpful❤

Crazy complex like a computer

Wow! Uh, I think I bit off more than I could chew... but I stuck it out and finished all 12min!! 🎆🎇✨

Individuals don't really understand how dangerous the rabies viruses really are...

Brilliantly explained with the help of the graphics. Thankyou so much.

But after it infects the cells what does it do exactly

How did they figure this stuff out?

All your video's are put together incredibly well! Thanks for these!!!

Be wary of wild animals, folks. Wear protection when you go out, like a sharp item or pepper spray.

I am soo happy the Cdc has aerosolized lyssavirus! I wonder if they will sell it to little old me? 😳 Feb 2020 acip meeting unfinished business. 😍

It's interesting that we still don't have a clear cure for this virus after it has shown symptoms.