ssRNA: Lyssavirus (Rabies) Replication Cycle

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  • čas přidán 29. 03. 2020
  • ssRNA: Lyssavirus offers a detailed illustration of the known replication strategy of Lyssavirus inside an infected cell. Lyssavirus also known as Rabies causes Rabies, one of the oldest recognized infectious diseases, and is almost invariably fatal in humans and other mammals. The virus is highly neuroinvasive. It is transferred via the peripheral nervous system to the brain where replication of the virus leads to the disease. The disease is preventable through vaccination and can be treated successfully by prompt post-exposure serotherapy and vaccination.
    Written and directed by Irene Petropoulou
    Co-directed and edited by Andrew Tucker
    Main scientific advisor: Dr. Christopher Clegg.
    Chief Animator: John Bardakos
    Narrated by Marianne Graffam

Komentáře • 78

  • @brisingarinstaridavis7084
    @brisingarinstaridavis7084 Před 3 lety +55

    Rabies is so frightening
    I feel so sorry for anyone
    Human & animal who are unlucky enough to get infected with it

    • @RRW359
      @RRW359 Před 2 lety +5

      Of courseit's frightening. Excess fear is one of the symptoms.

  • @user-ft3xr7ls7d
    @user-ft3xr7ls7d Před 3 lety +34

    let's erradicate rabies forever

    • @lotusflower6420
      @lotusflower6420 Před 3 lety +2

      Aren’t they saying Rabies will be eradicated by 2030. Let’s pray, it’s evil if you get it

    • @fatcat5817
      @fatcat5817 Před 2 lety +1

      Oops the cdc has it but in aerosolized form!
      So perfect!
      😌👌
      . Febru 2020 acip meeting unfinished business~

    • @teanation7800
      @teanation7800 Před rokem

      It has to go, at least we had a chance of surviving smallpox! When you get rabies there’s beasicakly no chance of survival
      Edit: Basically* sorry stroked out for a second

  • @benjaminweber9301
    @benjaminweber9301 Před 3 lety +45

    Amazingly detailed video! This should have way more views!

    • @irenepetropoulou59
      @irenepetropoulou59  Před 3 lety +14

      Thank you! It was a lot of work and with the support of many experts

    • @jozefvanriet2673
      @jozefvanriet2673 Před 2 lety +1

      I love your take on the matter, such high hopes for intelligent and attentive life!

    • @JimmyStruthers1000
      @JimmyStruthers1000 Před 2 lety

      @@irenepetropoulou59 Are you Greek Ms. Petropoulou?🇬🇷🏛

  • @anandsengupta1721
    @anandsengupta1721 Před 2 lety +3

    Brilliantly explained with the help of the graphics. Thankyou so much.

  • @subhankardey2044
    @subhankardey2044 Před 3 lety +1

    Thanks Dear... for such a nice illustration..

  • @2witty4uslayer2
    @2witty4uslayer2 Před 3 lety +13

    This was so scientifically explain that I understood 0

  • @danielivandittopro7544
    @danielivandittopro7544 Před 3 lety +3

    Nice job you did great don’t give up you can still get lots of subscribers

  • @himanshu_Chaudhary1001
    @himanshu_Chaudhary1001 Před rokem +2

    we need your knowledge
    please continue sharing

  • @bhanuprakashr2416
    @bhanuprakashr2416 Před 3 lety +4

    Very nice information and understood easily

  • @sharonbenitez4345
    @sharonbenitez4345 Před 3 lety +3

    Very helpful!

  • @yaseen5372
    @yaseen5372 Před 2 lety +2

    Very underrated 😒 video.
    Amazing👍❤️

  • @samuelknair1888
    @samuelknair1888 Před 3 lety +10

    Very helpful for my microbiology project for masters ❤️❤️❤️❤️❤️

  • @oksanaboiko5263
    @oksanaboiko5263 Před 2 lety +1

    Great Job Irene, Andrew, John, Marianneand all the team!

  • @miunya
    @miunya Před 2 lety +5

    I was wondering why schools never taught me this but ireland has been rabies free for a long time but I'm glad to know incase I ever travel or just in general

  • @upscaleavenue
    @upscaleavenue Před 2 lety +10

    Viruses are so amazing. I am constantly in awe.

    • @JimmyStruthers1000
      @JimmyStruthers1000 Před rokem

      Viruses are terrible and they all need to be destroyed

    • @upscaleavenue
      @upscaleavenue Před rokem

      @@JimmyStruthers1000 Viruses are actually integral to the ecosystems of this planet. Without them, our world would be very, very different, and not in a good way. We might not have even survived as a species.
      Phages in the ocean, for example, maintain equilibrium by culling populations of bacteria every single day.
      Viruses won't be destroyed, no matter how hard we try. We can't conquer nature. And, why would we want to?

  • @saniaraj8355
    @saniaraj8355 Před 2 lety +2

    Very helpful❤

  • @user-ok2cr7gk5j
    @user-ok2cr7gk5j Před rokem

    Continue please ❤

  • @ykl178
    @ykl178 Před 3 lety

    Thank You

  • @NamuraIdhunita
    @NamuraIdhunita Před 9 měsíci +1

    One of the most amazing videos on the subject I've seen!! Wonderful animation, thank you so much for all your work!

  • @ra-ge
    @ra-ge Před rokem

    Incredible how these things operate

  • @electrowizard2658
    @electrowizard2658 Před 2 lety

    So nice

  • @NilTheBear
    @NilTheBear Před 3 lety

    Informative

  • @miz6294
    @miz6294 Před 2 lety +1

    Crazy complex like a computer

  • @lgg2304
    @lgg2304 Před 2 lety +3

    Wow! Uh, I think I bit off more than I could chew... but I stuck it out and finished all 12min!! 🎆🎇✨

  • @danmiller2177
    @danmiller2177 Před 2 lety +2

    Individuals don't really understand how dangerous the rabies viruses really are...

  • @leogelynromano3564
    @leogelynromano3564 Před 2 lety

    Great!!! thankyou so much for the information!! Now, I understand a lot. ♡♡♡

  • @VinhPham0708
    @VinhPham0708 Před 2 lety +5

    This video is really helpful!. Do you have a script? because the automatic subtitiles is not clear some parts :((. Thank you so much.

  • @KingVulpes
    @KingVulpes Před rokem +3

    Takes one mutation to screw us all over

  • @Widderic
    @Widderic Před 2 lety +2

    So are the viral messenger RNAs any different than electrical circuitry components and how they interact with the each other? My head is exploding over this stuff lol.

  • @igo7434
    @igo7434 Před 2 lety +2

    Thanks for this video. Very informative! Worse way to go if you get rabies.

    • @Zebraaaaaaa668
      @Zebraaaaaaa668 Před rokem

      How long do rabies survive in land under sunlight?

  • @savagephoenix4979
    @savagephoenix4979 Před 2 lety +3

    It’s more deadly than Ebola which is why I’m here 😳

  • @hxocreates4897
    @hxocreates4897 Před 3 lety +1

    pleas tell what the capsid of rabies virus is

  • @leifdux7277
    @leifdux7277 Před rokem

    They look like the hair rolls to curl your hair.

  • @up67bloge
    @up67bloge Před rokem

    We had got the dog vaccinated 9 months ago, after 9 months of getting the full course, I touched it again, so I went and got the full course done.
    Looks like I had to get only two waxing done Sharif

  • @vikasbiliye5023
    @vikasbiliye5023 Před rokem +1

    Given that we have such detailed information, cant we maybe hack this virus system and make it dysfunctional forever?

  • @prettyprudent5779
    @prettyprudent5779 Před 2 lety +5

    Be wary of wild animals, folks. Wear protection when you go out, like a sharp item or pepper spray.

  • @leonidaskaragiannis7875

    What is it?

  • @jericho4298
    @jericho4298 Před rokem +1

    Whoa! This is very informative. Imagine you are being assassinated using a small gun that shoots a very small dart that is filled with rabies (you wouldn't even notice it) then 1 week later... POOF!

  • @phycopath2122
    @phycopath2122 Před rokem

    pov you fall asleep first at the sleepover

  • @wiki5566
    @wiki5566 Před 2 lety

    Are you there? Alive?

  • @ROT8TED
    @ROT8TED Před 2 lety

    Got so lucky recently with hematoma instead of puncture trying to feed racoon, lesson learned...dumb me...

  • @weiner_hands-guy914
    @weiner_hands-guy914 Před 2 lety +1

    I really can't follow this video completely. Too scientific for me and I don't understand a lot of the terms. I'm definitely not ready for this content yet.

  • @fatcat5817
    @fatcat5817 Před 2 lety +1

    I am soo happy the Cdc has aerosolized lyssavirus!
    I wonder if they will sell it to little old me? 😳
    Feb 2020 acip meeting unfinished business. 😍

  • @headrush2190
    @headrush2190 Před 3 lety

    based

  • @dnap2526
    @dnap2526 Před 2 lety +3

    How did they figure this stuff out?

    • @A.K.00
      @A.K.00 Před 2 lety +4

      That is what science and research is all about

    • @noobnesz
      @noobnesz Před rokem +1

      Petri dishes, microscopes, and a whole lot of time.

  • @dnap2526
    @dnap2526 Před 2 lety +2

    But after it infects the cells what does it do exactly

    • @JohnnxxKing
      @JohnnxxKing Před 2 lety +1

      Well u get to madness and suffer from breathing and ur eye goes insane and u cant even control it it moves it own when it on final stage
      Its almost like zombie apocalypse if this disease keeps going

    • @raypunn
      @raypunn Před rokem

      ​@@JohnnxxKing but why

    • @Pikachu-xz9gb
      @Pikachu-xz9gb Před 8 měsíci

      @@raypunn fok u that's why.

    • @TheWagonroast
      @TheWagonroast Před 3 měsíci

      ⁠@@raypunnIt begins to take over your brain, which causes less control over yourself, and causes aggression, the inability to breathe well, etc because of dead/malfunctioning brain cells

    • @raypunn
      @raypunn Před 3 měsíci

      @@TheWagonroast i mean what are the exact chemical reactions that cause it to control nerve cells in that way

  • @salvadorhirth2919
    @salvadorhirth2919 Před rokem +1

    If the genome of rabies viruses do contain one or more palindromic sequences, (I believe that such sequence probably exists), at least three bases upstream and downstream from the core of the palindromic sequence and one species of bacteria certainly produces a restriction enzyme that recognizes and cleaves said palindromic sequence. Then, hopefully, a novel class of antiviral therapy will be created if the target cells can be transfected with a gene encoding the restriction enzyme.

  • @goksenincakr2466
    @goksenincakr2466 Před 2 lety +3

    05:32 Gucci Gang :D

  • @pzyxn2745
    @pzyxn2745 Před 3 lety +1

    Amogus

  • @TylerDWard
    @TylerDWard Před 3 lety +1

    Why did I think I was watching SARS-COV2...maybe there's similarities

    • @A.K.00
      @A.K.00 Před 2 lety

      That they are all viruses?

    • @themaestro3034
      @themaestro3034 Před 2 lety

      This is how RNA viruses work on all cells.

  • @rajeibanvijeyakumar8471
    @rajeibanvijeyakumar8471 Před 6 měsíci

    im the 300 subscriber. thank me later.

  • @bobibakar
    @bobibakar Před 2 lety

    All is lie, nothing work is done to get clear virus operation activity.

    • @A.K.00
      @A.K.00 Před 2 lety

      Really? Then you do it

  • @Byeeveryoneiwillgoneforever

    T-pose