Rabies : Pathophysiology, Signs & Symptoms, Diagnosis & Management (Pre & post exposure prophylaxis)

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  • čas přidán 6. 07. 2024
  • Rabies is an extremely fatal viral disease affecting the central nervous system, and caused by the highly neurotrophic rabies virus.
    In this video I discuss about;
    1. The rabies virus & its transmission
    2. Pathogenesis of rabies
    3. Clinical presentation
    4. Diagnosis
    5. Management of rabies ( Pre exposure & Post exposure prophylaxis )
    I would highly recommend you to watch the video till the end.
    And the most important topic in this video is the management of rabies.
    Link to WHO guidelines on management of rabies;
    www.who.int/rabies/PEP_Prophy...
    Chapters :-
    00:00 - Intro
    00:35 - Rabies virology
    01:18 - Pathogenesis of rabies
    03:22 - Signs & symptoms of rabies (prodromal phase & acute neurologic phase)
    07:30 - Diagnosis of rabies
    09:04 - Treatment & management of rabies
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Komentáře • 92

  • @medtoday
    @medtoday  Před 3 lety +29

    To all the students who watch Med Today videos;
    Do not rely on videos for in depth details on a certain topic. Use the videos as a guide to understand the basic picture & concept behind that particular topic. Always read textbooks to improve your knowledge. And gather information from reliable web sites like "Medscape", "Pubmed", And "CDC". Find the latest guidelines & articles published by healthcare experts, and study them. Good luck, Future doctors!

  • @hunterw3866
    @hunterw3866 Před 3 lety +18

    It’s amazing to me how this disease has managed to stay relevant.

    • @nahalastone8027
      @nahalastone8027 Před 2 lety +5

      It's probably the oldest virus we know. Been around since 2000BC.

    • @MichaTheLight
      @MichaTheLight Před 3 měsíci

      Search for rabies hospital bill, then you know. A men in the USA payed 27k. USA is such a broken country.

  • @mahsamazdak2755
    @mahsamazdak2755 Před 2 lety +7

    This is one of the best organized, full-covered videos on medical lessons
    TNX a lot!

  • @utsavimishra106
    @utsavimishra106 Před 2 lety +2

    Clear and concise ! Thank you

  • @cyst3766
    @cyst3766 Před rokem +3

    Amazing! Best video on rabies so far

  • @user-ko2mp5xb8t
    @user-ko2mp5xb8t Před 11 měsíci +2

    Amazingggggggg 👏 👏 👏 👏 👏 please upload other lectures( diseases ) which are related to CNS

  • @McDonnell-Douglas_DC-10
    @McDonnell-Douglas_DC-10 Před rokem +2

    The narrator's English is excellent, just like the rest of the video.

  • @mennaamin5079
    @mennaamin5079 Před 2 lety +6

    Great illustration , thanks alot 🥺💖💖💖

  • @asmamuhammad1588
    @asmamuhammad1588 Před 2 lety +2

    Amazing 👏

  • @kingpop101
    @kingpop101 Před rokem +1

    heard how he said pathophysiology and came directy to the comments

  • @tal4562
    @tal4562 Před 3 lety +3

    Is it still safe for the active immunization even RIG is given on day 7 using intradermal? I hope you will reply thank you.

  • @JungleLibrary
    @JungleLibrary Před 3 lety +8

    Is this a computer voice? Can you please tell me which one you use? It's very good.

    • @medtoday
      @medtoday  Před 3 lety +9

      Yes!
      I use a website called "Watson text to speech demo".

  • @o0Skull0o
    @o0Skull0o Před 3 lety +2

    Brilliant 👍👍👍

  • @enexe6229
    @enexe6229 Před rokem +2

    how long does acute neurologic phase last and does the secong phase occurs after the of the first one (2-10 days)?

  • @vasuk8382
    @vasuk8382 Před 2 lety +1

    Sir, u mean 2 prodrome phases first after the bite and then after the incubation period ??

  • @shivamdubey4783
    @shivamdubey4783 Před 3 lety +1

    That 7th day vaccine is 7 day after first vaccination or 7 th day after second vaccination PLZZ tell

  • @agapayharveyt.718
    @agapayharveyt.718 Před 3 lety +2

    Thank you for the information. But may I know what application or website do you use for editing videos?

    • @medtoday
      @medtoday  Před 3 lety +2

      I use powerpoint to make the slides and animations. And a simple video editing app from playstore(only to cut and merge videos + mix the audio with video)

    • @FITTOHEALTH
      @FITTOHEALTH Před 3 lety

      czcams.com/channels/pb_vgEpdZ8tRhlpyJhbGQg.html

  • @vuthieny9516
    @vuthieny9516 Před 8 měsíci +1

    If a person was bitten and infected the virus, could we think about the X-rays to treat the wound?

  • @VyYo7072
    @VyYo7072 Před 3 lety +1

    sir my question is category 1 2 3 in teeno ke injcetion ek hi lgte h ya teeno category ke alag injections hote h

  • @unknownperson80989
    @unknownperson80989 Před 2 měsíci +1

    0:39 Hey, consider using dark colors for your text.

  • @elizabethlopez6233
    @elizabethlopez6233 Před rokem +2

    I have recently been bitten and can't get any good information or the vaccine anywhere as of yet. I have called so many places and get the run around with another number to call with no real answers. Ridiculous. I'm beginning to get nervous from this bite in hopes it not got rabbis.

    • @christinebyaruhanga
      @christinebyaruhanga Před 5 měsíci +1

      Hello there, are you ok? If yes, please reply me, am in the same situation here in UAE.... can't find a hospital with a rabies vaccine

  • @angelinacastro8626
    @angelinacastro8626 Před 2 lety +2

    I was wondering when i first saw this and i was curious about it ontill i gave it a try because i was diagnosed with hpv for months dr bante helped me cure it thamkfull for everything dr bante thank you so much

  • @saakithyasaakithya6864
    @saakithyasaakithya6864 Před rokem +1

    Without biting can I get parvovirus vaccine while feeding in my hand 1 year

  • @mkshoronadmin8969
    @mkshoronadmin8969 Před 17 dny

    Are there any symptoms during the incubation period of Rabies?

  • @fatcat5817
    @fatcat5817 Před 2 lety +1

    The fact the cdc has airborne rabies. In february 2020 acip meeting "unfinished business". Manipulating the most lethal virus in the world. What could possibly go wrong? 😳

  • @angelinacastro8626
    @angelinacastro8626 Před 2 lety +1

    I was wondering when i first saw this and i was curious about it ontill i gave it a try because i was diagnosed with hpv for months dr bante helped me cure it thamkfull for everything dr bante thank you very much

  • @jerilrollenas9675
    @jerilrollenas9675 Před 2 lety +2

    Can I ask? If I finished two booster shots, and I got bitten again a day later, will I still need to get another booster shot?

    • @mrduck7957
      @mrduck7957 Před 2 lety +1

      No, booster shot last more than one day, from few months to a year. Check with your doctor just to be safe.

  • @sujithrasuji8287
    @sujithrasuji8287 Před 3 lety +2

    Is this disease spread from the infected person to other person by direct contact...like drinking water on same glass...

    • @mrduck7957
      @mrduck7957 Před 2 lety +1

      Yes it can spread through contamination

  • @143wensheng
    @143wensheng Před rokem +1

    bitter by the cat, the area that bitten.got swollen ,after 2 days the cat died :(

  • @sudharakaedirisinghe5630

    Well done😍😍😍

  • @darwintaloza7360
    @darwintaloza7360 Před 3 lety

    The content is excellent, but the computer voice, I find the monotonous way of speaking not good. I think it is best when just like the voice of neisseria and TB of your previous videos. Thank you.

    • @FITTOHEALTH
      @FITTOHEALTH Před 3 lety

      czcams.com/channels/pb_vgEpdZ8tRhlpyJhbGQg.html

  • @margaretmateka2388
    @margaretmateka2388 Před rokem

    I received the vacation

  • @aurevior1982
    @aurevior1982 Před 2 lety

    Sir ..I want to ask you ..if I touch the rubbish that come from stray dog mouth .. this dog I drive away before take the rubbish ..actually, it will infect me or not ?because the dog still alive without any symptom ..it is 20 days after the incident .. I feel worried because when I asked the doc at my place they said I can't get infected because my place are free from rabies and there is no bite or scratch or open wound at me..please sir reply my question 🙏 ..

    • @medtoday
      @medtoday  Před 2 lety +2

      Yah. If it is a rabies free area, there is no need to be worried. And as the dog is still alive and there is no direct exposure, the chance of getting rabies is also less.

    • @aurevior1982
      @aurevior1982 Před 2 lety

      @@medtoday thanks sir ..for your answer make me free from worry.. because some mammal or dog don't have simptom even though it had rabies..

  • @margaretmateka2388
    @margaretmateka2388 Před rokem

    I was a victim of dog bit in January 2023

  • @bishalthapa8820
    @bishalthapa8820 Před 2 lety +1

    Hello sir
    I was bitten by a monkey I didn't injected monkey was pet And it's been 7 years and no symptoms has been matched to me im healthy fit and fine is there any danger to me plz give me suggestions

    • @user-rv7xx3ut2g
      @user-rv7xx3ut2g Před 2 lety

      Did the monkey die in the first 10 days?
      If it didn't you are okay :)

    • @bishalthapa8820
      @bishalthapa8820 Před 2 lety

      @@user-rv7xx3ut2g no sir the monkey were alive

  • @israaali747
    @israaali747 Před 3 lety +3

    Hello, Iam wondering if you have questions for midterm exams for virology 😊

    • @medtoday
      @medtoday  Před 3 lety

      Well, I can give some. But don't know whether they would match with your syllabus.

    • @mrduck7957
      @mrduck7957 Před 2 lety

      @Julien Du Casse you are still alive most likely your kitten didn't carry the virus. If you can get vaccine go for it, if you are at risk of other bites.

  • @TheMathstat
    @TheMathstat Před 3 lety

    Very nice dear actually i m writing an article on tabbies for mathematical modeling so i m using ur wording hope it will not b a part of plagiarism

    • @TheMathstat
      @TheMathstat Před 3 lety

      Sir tell me is this ur own wording ?

    • @medtoday
      @medtoday  Před 3 lety

      All the best

    • @medtoday
      @medtoday  Před 3 lety +1

      Yes! Most of it. But I think I created some parts of the audio with an article of "Medscape". I don't remember now. I think it wouldn't be a problem though.

  • @kalpabandara3891
    @kalpabandara3891 Před 3 lety

    Ok professor good work done but go to the pocket and batch meetings too sir 😁😁😁😁😁😁😂😂😂

    • @medtoday
      @medtoday  Před 3 lety

      😂😂😂 Will consider that too

  • @yournearbylakotashaman6380

    I am never gonna take a walk in the park.

    • @medtoday
      @medtoday  Před 3 lety

      Good idea

    • @yournearbylakotashaman6380
      @yournearbylakotashaman6380 Před 3 lety

      My love for wild animals dropped to the floor and turned into fear and anxiety

    • @medtoday
      @medtoday  Před 3 lety

      @@yournearbylakotashaman6380 People who love animals are known to have a good heart. Just don't try to change who you are. But interact with them more carefully than you did previously.

    • @yournearbylakotashaman6380
      @yournearbylakotashaman6380 Před 3 lety

      @@medtoday well, yeah but my anxiety is sometimes.i try I sometimes believe my cat has rabies and is spreading it everywhere.

    • @medtoday
      @medtoday  Před 3 lety

      @@yournearbylakotashaman6380 If so, it would be better if you vaccinate your cat regularly

  • @c.m.139
    @c.m.139 Před 2 lety +1

    I GOT SCRATCHED BY A SQUIRREL IN THE FINGER. I LIVE IN ITALY. SHOULD I WORRY? Pls answer

    • @user-rv7xx3ut2g
      @user-rv7xx3ut2g Před 2 lety

      Well, since rabies doesn't really transmit to scratches, its a 50/50 since you can get them if they licked it or like that.

    • @arthurgarcia4389
      @arthurgarcia4389 Před 2 lety

      I got bit by a dog 2 months ago...im still alive. Never took a shot.
      So far it looks like rabies is transmitted usually thru saliva. A scratch from a squirrel isnt usually how rabies enters the body. Unless if after the scratch the squirrel manages to lick the open wound then maybe.

    • @mikot4439
      @mikot4439 Před 2 lety +1

      @@arthurgarcia4389 the incubation period of rabies can be range between 3 month to over a year , so I suggest you check on the health of the Dog because it usually dies within 10 days if it has rabies

    • @arthurgarcia4389
      @arthurgarcia4389 Před 2 lety +1

      @@mikot4439 thank you for replying. I havent felt any symptoms since the symptoms. I dont know what happened to the dog but I feel ok. Im guessing im in the clear? I hope.
      Thank you again for replying....I appreciate you!

  • @adi2153
    @adi2153 Před 3 lety +1

    A dog bitten my toe 3 months back...i got vaccinated (5 doses on time) without immunoglobulins 😔😔...i am in fear coz for past 2months i am facing tingling at the site of the bite...please help me.

    • @medtoday
      @medtoday  Před 3 lety +1

      Go to a Doctor immediately

    • @adi2153
      @adi2153 Před 3 lety +2

      @@medtoday doctor said that its not due to rabies it can be nerve damage...he said rabies symptoms dont last for 2 months...and the dog that bit me is still alive.

    • @medtoday
      @medtoday  Před 3 lety +4

      @@adi2153 Rabies symptoms may appear even after an year from the exposure. But, no need to worry if the dog is alive.

    • @adi2153
      @adi2153 Před 3 lety +2

      @@medtoday thank you.

  • @adi2153
    @adi2153 Před 3 lety +1

    Why antibody cant kill the virus present in the motor neuron....is it true that if the virus attached with neuron then death is 100% certain ?
    ..what happens just after prodomal phase.?? Can prodormal phase last for years or months ? Some reseachers says that antibody can enter in neuron...thats how some people survived rabies

    • @medtoday
      @medtoday  Před 3 lety

      Well, usually antibodies are produced against rabies virus. But unfortunately almost always they are not produced in sufficient amounts to prevent the disease progression.
      It is possible for someone to get rabies years after an exposure. This is due to the prolonged incubation period of the virus. During incubation period, the person is asymptomatic. Once the incubation period is over, then the prodromal phase starts, followed by the neurologic phase.
      There may be a few cases that people survived without any prophylactic treatment, but the usual outcome is death if prophylactic treatment has not initiated as soon as possible.

    • @adi2153
      @adi2153 Před 3 lety +1

      @@medtoday thank you sir.....i was afraid of rabies coz bite site was tingling for almost 3 months...now its gone...😁😁i am good and stress free now.

    • @mansinilakh8598
      @mansinilakh8598 Před 2 lety

      Even i question the same qhy the virus is not killed with after the vaccination??

    • @mansinilakh8598
      @mansinilakh8598 Před 2 lety

      Antibody cannot enter the neuron why??

    • @mkshoronadmin8969
      @mkshoronadmin8969 Před 17 dny

      are you ok, now?

  • @briarrosecabigon7013
    @briarrosecabigon7013 Před 3 lety

    a

  • @Sanguen666
    @Sanguen666 Před 3 lety +1

    wow it's almost as fatal as covid! :O

    • @medtoday
      @medtoday  Před 3 lety +11

      It's actually much more fatal than COVID19. If you get COVID19, still there's a chance of survival. But once you get rabies, you wont survive.

    • @lun4ticplayz
      @lun4ticplayz Před 8 měsíci

      Covid's fatality rate is 3%. Rabies' fatality rate is 100%.