Scientists Used DNA To Create World's Smallest Antenna Ever For an Unusual Reason
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- čas přidán 24. 07. 2024
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Hello and welcome! My name is Anton and in this video, we will talk about the smallest antenna ever made - built from DNA
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creativecommons.org/licenses/... - Věda a technologie
You’re a natural educator, Anton. Thank you for pursuing your calling.
Yeah, his autistic dedication to math, near complete ignorance of evolutionary biology and politically correct eye-rolling virtue signaling of treating "space colonization" as a racial slur reminds me of my middle school teachers.
I like how you can segue from the vastness of the cosmos to the microcosm of human DNA.
I love this channel. Some of the best science communication on the internet.
Yes, Anton does my reading for me and gives a decent report on interesting applications
Testify! Wonderful person.
I don't know a lot about proteins, but even I can tell this is gonna be revolutionary. Since protein folding is a hard problem to simulate, I assume lots of people thought the main breakthrough would come from using quantum computers for that. But what better way to find out what a protein does than to just... look at what it does!
Very easy to disturb it"s Habitat.
Lately there's been a lot of work with AI to predict protein folding and apparently, it's making pretty good progress.
Why do you believe this technology was developed?
What will it be used for?
@@PetraKann for evillllllll hail satan 666
@@omarthesecond9768 ..elaborate
"Finally! I can start receiving signals from my energy crystals"
"Our records indicate your Crystal Car Coverage plan is about to expire..."
or that cell tower
That's demonic
@@TOMMY-WANT-WINGY depends on intent I believe
@@conservingcommonsense4980 the little research I've done, crystals are in line with yoga and tarot cards
Thank you Anton for spreading all this information. You are truly a wonderful person.
Wouldn't it be weird if DNA was actually an antenna already and we are just now starting to clue in?
We are antennas!
Before getting to exited: "The DNA- or PEG-based fluorescent nanoantennas contain a fluorescent dye at one end, such as fluorescein (FAM), and biotin at the other to facilitate attachment (Start)" so look for fluorescent tagging to really understand that the DNA itself is not the antenna (better to say not the used antenna here and as a electronic engineer would say DNA is not more or less an antenna then anything could be an antenna).
@@Techmagus76 have you ever considered how DNA is bundled almost exactly like a copper wire Is for a circular radio antenna?
Not weird. You are spot on.
Now you know why they called it the pandemic of the unvaccinated, see every Craig VENTER videos though.
I think you're right, this can change everything, the key word being "dynamic". we've been able to "look" at the tiny world for a very long time now, but to watch it in motion is a very big factor in understanding things at this tiny level. Again Anton You Rock!
Love the pic of the old school OTA network TV antenna shown for about 10 secs. My family had one of those when I was a kid.
Conspiracy theorist were saying this two years ago, even I thought they were crazy.
A frightening example of the lack of safeguards in place to protect the definition of what life is and what defines it.
Yes! This!
DNA molecules can store up to 215 petabytes, or 215 million gigabytes, of data in a single doubled stranded molecule, making it one of the highest storage density mediums in the world.
That's mind blowing!
Bet it's read write speed is shit tho
Is that taking into consideration that one of the strands is just a reversed copy? Or that DNA uses a coding system that is much denser than binary by using 4 bases to code instead of 2?
@@chadnuts technically, it's more than just a 4 base code. since the bases can be modified, but idk if that can be applied to artificial information storage.
@@Meleeman011 Yep. And the error correction is sub-par. fascinating all the same.
@@vforwombat9915 Fully expended without disruption to the structure, it is 8 base code.
"...it has never been done before" riiight
Thank you.
At time stamp 2.25 there is a small animation of a walking figure. BBC horizon covered this topic in huge depth a while back. The animation was superb. My memory on this topic is focused on the animation therein. However , this entire topic , presented here - is amazing. Well done Anton.
It's a great demonstration but the real thing is a bit more chaotic and they can only walk one way, But science is only going to get harder to communicate as we look deeper into the unknown.
Thanks Anton, I hope you grow from strength to strength.
this is amazing, opens whole fields of research , way to go science!! and thnxs anton for bringing it to us!
i love how informative your videos are while still being entertaining enough that i want to watch them.
Thank you Anton for taking me along !
Wonderful as always anton 😉👍
Take a shot every time Anton says “a lot of”
Good on you Anton, always find your stuff very interesting,take it easy mate.
7:07 That actor portraying a scientist fumbling around with the microscope might have better luck if he took off his glasses whilst using the microscope.
What could possibly go wrong? Momicron or antennacronitis?
No one seems concerned about protein privacy.
Biohacking
Proud to hear you are from Montréal ! You are amazing !! Thanks for sharing your knowledge to us all !!!
Remember the implications of this video when you next hear someone say that 'we are light'. Then put a smile on your face and carry on proud, you glorious bioluminescent sacs of water and intelligent starlight! XD.....
Appreciate your presentations
Nice post, Anton, but this time I am going to call out the hype of this work.
First, it’s an old technique: chromaphore oligonucleotides have been used in PCR assays for decade(s).
Second, while a novel application to protein dynamics with new and interesting results, protein fluorescence spectroscopy is even an older methodology (four decades).
The major limitation to this technique is to find a suitable analogue that binds to the protein but does not affect “native” behavior.
I would suggest taking a look a quantum spectroscopy - that method has greater potential to clearly define ultra-fast macromolecular dynamics.
Yes anton keep it up with the videos you are wonderful
Fellow Montrealer here.. just watching and learning from you. Thanks for all the great content you provide us with.
Getting closer to 1 mil. You definitely deserve it!
Very nice! Thanks! I have often wondered about optically energized processes in living organisms. This seems to open a new window into those possibilities!
Almost to a million subs Anton! You deserve it buddy keep up the good work
Always wonderful watching your videos
In this case you have explained us a future Nobel prize winner in a fantastic easy way
The implications of this are truly frightening.
Bravo les gars de Montréal!!
Hello wonderful Anton! Actually, we have a lot of methods already for monitoring protein dynamics - most prominently NMR, but also Deuterium exchange mass spectroscopy, 2D IR spectroscopy etc. The technique described in the paper actually falls among those techniques that go beyond Diffraction-limit.
I am missing something. I agree with your statement that many techniques exist for monitoring protein dynamics, but why are you concerned about the 'diffraction limit' here? XRD was not used in this study at all, and deuterium exchange MS and NMR (solid state or solution) are not diffraction limited techniques.
Can one of you guys tell me please if these DNA antennas are built to survive a mammalian immune system? Or are they only using them externally? I'm not trying to be controversial, just ruminating. They can receive and transmit data??
@@Opti-Mystic Unfortunately, it seems that Anton and many of the commenters here are misunderstanding what really is happening with these putative DNA antennas. If you read the published work - Anton included a link to the paper - it would be obvious to those with a chemical or biological background that the DNA was used only as a transporter macromolecule for an attached fluorophore probe molecule whose fluorescent emissions were monitored in real time and in vivo (in the native live cell environment). These emissions are especially useful in a process called Förster resonance energy transfer (FRET) where the fluorescent emissions of one fluorophore molecule is absorbed by another nearby fluorophore molecule as a function of their separation, relative orientation and molecule type. This gives critical information about the kinetics - or dynamics - of what is going on with proteins, for example. In this study the DNA fundamentally just served as a means to introduce the fluorophore molecule into the cell; the DNA itself was not as critical as everyone seems to think here because PEG (PEG = polyethylene glycol) was also used similarly with comparable observed trends to DNA. So, the DNA itself was not some sort of transmitter or antenna in the sense that the physicists or engineers here are thinking about it. Having said this, there is an emerging area of research called optogenetics, where one goal is to modulate or control the process of genetic transcription or translation using intermediate molecules, engineered proteins or nanomaterials that could turn on or off gene expression using optical signals. At the same time, DNA itself is being explored as a robust means of long-term information storage; but the information is stored as a function of nucleotide sequences in the DNA, not wirelessly transmitted data.
Finally, I am not aware of any research exploring the immune response to such modified DNA, if for no other reason that this is an analytical technique used by researchers to study biological processes as opposed to a clinical diagnostic tool to treat disease.
Hope that this helps you understand this topic a little better.
@@dgc0120 Thank you, I will mull that over.
Yes, I'm looking at the optogenetic potential and also gene therapy applications.
This is just mind blowing Anton! TFS, GB :)
Amazing, thanks Anton!
Very interesting, thank you🤗
Wait, what? You come from Montreal? Wow, after all these years, I just learn that!
Love your videos and channel, good sir. Keep doing you.
Mr. Petrov, I learned in my childhood that sounding a pitch that matches one of my violin strings would cause that string - otherwise un-touched - to resonate "in sympathy" with the frequency that impinged upon it. (I'm just trying to think thru this concept here...)
Later study clarified that the sound energy was optimally absorbed with the natural harmonic series of the string,.. but this will work for any structure that has a natural shape that resonates to a fundamental pitch, and its harmonic series: 1/1, 1/2, 1/3, 1/4... et cetera. That's the alternating compressions and rarefactions of the air molecules impinging on the fiddle string (or guitar, or piano, etc.) and adding energy like one child pushing a friend sitting in the seat of a Swing Set each time the friend returns in that pendulum movement.
Later in physics class, we learned that this "sympathetic resonance" also works with electromagnetic energies, with transverse as well as longitudinal waveforms. I don't recall hearing of any upper or lower limit to the frequency ranges our present Reality can generate.
These principles as applied to structures at the scale of molecules and atoms, seem to lend themselves to mathematical analysis of energy patterns - absorbed and emitted, in response to samples of known composition being irradiated with known frequencies... Like X-ray Crystallographic analysis of structures.
• Seems as if the purity of the irradiated target molecule "samples" would be a sticky challenge in all that, along with calibrating the signal going in and returning!
• So, Those HIGH Frequencies seem to imply High Energies as well. And that makes me wonder how much energy a DNA strand can absorb without exceeding the chemical bonds that keep the structure intact.
For instance, don't astrophysicists detect Giga-electron-volt Cosmic Rays from 4th or 5th-generation "daughter" particles, so they are _INFERRING_ the characteristics of the Original cosmic ray that crashed into our upper atmosphere???? Jeez-0-Peez, that seems to be a big pile of assumptions pile on top of each other!
I'm amazed at the advancement it done almost every day yet it is years of
searches behind. Were it leading us to?
OK, couple things, right off, holy OMG wow! It's amazing what I've learned from these videos! Thank you so much. Wonderful presentation, clearly breaking down the minute details for us non-genius IQ types, amazing work.
Okay, this is awesome, and it’s right in my field.
Love your interests in science .
I was almost going to call you out on not giving us a “Hello Wonderful Person” but you pulled through.
My favorite science channel. Hope he hits 1 million soon!
Thanks for sharing.
Soon 1M subscribers ! THANKS from France
This opens a lot of doers and we’re going to have to rethink a lot of what people use to say...
Oh yeah.......
It's all coming together.
Great idea. Can’t wait to see all the applications for this!
Its the covid jab.
If they can make a 2.4Ghz antenna... I bet Express LRS receivers are going to use them. 😬
Great, now diseases can have Wi-Fi.
Do you want Borg? Because this is how you get Borg.
I doubt the world powers use it for good...
@@nerdtendo2300 you are making yourself sound like an anti-vaxxer
Excellent Vid
Thank you Anton
I am amazed by the size and scope of the universe. I am also amazed at the microscopic universe that exists.
It's a bit like a remote debugger in the programming world. Very useful!
I like your frequencies when you say things Anton.
It doesn't take a person long to figure out that different DNA combinations will operate differently and may be a key to the type of frequency expected.
We might be asking a supercomputer about that soon.
Since I'm not part of the science cult I get nothing for my contributions, Sad yet true.
Bravo Anton !!
Thank you for your excellent summary of this lovely bit of chemistry. I will find and read this paper to be sure, but from your comments here I must confess to being only somewhat impressed by the novelty of this work. People have been purposefully attaching chromophores (absorbers of visible wavelength light) to proteins for at least 7 decades now, and they have been studying a large array of various dynamical processes as well - conformational changes, electron transfer reactions, excited state relaxation kinetics, energy transfer, ligand binding, phosphorylation and other small group reactions...it's long, long list which has grown as time-resolved spectroscopic methods have proliferated. Molecules are by their very nature on the "nano-" scale once they have more than a few atoms strung together, and I'm afraid that pulling out the nano- buzz word has now become a somewhat over-used attention grabber (peruse the literature and you'll see this done all over the place).
Now they just use the Jab!
On the march to 1 million subs! Let’s get Anton there
humain Wifi antenna for talking to each other without speaking xD
be honest this sounds more dangerous then ai the dangers in this could be massive i feel in the wrong hands
'Dangerous!' cried Gandalf. 'And so am I, very dangerous: more dangerous than anything you will ever meet, unless you are brought alive before the seat of the Dark Lord. And Aragorn is dangerous, and Legolas is dangerous. You are beset with dangers, Gimli son of Glóin; for you are dangerous yourself, in your own fashion.
Dude this is his scariest video yet. It should be thrown in the fires of mount doom. This will be used to enslave people via microscopic surveillance
@@adinkra86 lol
This is an interesting topic. There’s a technique using optogenetics to manipulate neurons with various colors of light.
And they called them 'crazy conspiracy theorists'.......
This groundbreaking in so many ways example maintaining sells health research and understanding of DNA control and interaction with cells proteins possible benefits life extension
As with every invention/discovery, there will be those with ulterior motives for its use.
Really cool. 👍
Well this is not a concerning development. I'm certain that this level of miniaturisation will never be abused.
🤞🏻😒
Looking at the comments here? We're effing done for. I'm all for science but the lack of questioning of what's going on with this is bordering on religious faith.
@@TGBurgerGaming haha good comparison
Anyone not thinking nanites, isn't thinking.
To all those concerned antenna is the word being used in the strictest sense of the word.
This will work great as an adjunctive with traditional reagent manufacturing
exciting new technique!
This is a little of topic but on the night of the 19th i think. I was looking at Orion (i live in Melbourne Australia) it was 2am when i noticed Rigel across opposite beetlguse went very bright then over a 10min period it slowly dimmed to the point i thought it was going to disappear. There were no clouds a full moon just happened it was very odd how the star just brightened suddenly looking large and very striking then dimming to a very dull point.
If anyone can tell me why this happened i would be very appreciated. Thank you 😊
This kind of reminds me of a few articles/papers on possibly using quantum dots in a similar way. Hm, I never actually thought about proteins themselves though!
Beautyfull, also your explane and video background 🧡🎈💞👍
Commercial science B-Roll is hilarious. This is huge! A new potential look into the microcosm. Cells are soooo sophisticated.
Thank you, Anton. Tiny antennas on the hunt for proteins!
4:30 anyone else reminded of frosted cheerios?
The longest wait ever for "Hello wonderful person" 😳
Futurama's ad's beeing beamed directly into your mind will be true sooner than predicted.
He who produced the signal received it the whole Universe morphing!
FAM: Can you get me a picture of that molecule?
CAL: I got you, FAM.
Interesting!
Anton Petrov Could this new Tech also give use glims into the quantum world? Maybe detect if particles are strings or partial along with other quantum functions etc?
mRNA can be used to synthesize these organic antennae, DARPA has been leading this research since 2013. The applications for this tech are endless.
@@steveatkinson85 Truly amazing technology, the ability to monitor a hosts biological data wirelessly without the need of an internal artificial power source.
@@kevindegenaar So these DNA antennas can exist internally without being eliminated by a mammalian immune response? And they receive and transmit data ?
@@Opti-Mystic There is an immune response, however the application of an immunosuppressant can have great results in slowing this down. Data transmission is achieved by means of a nearby wireless device( Preferably hand-held). Exactly the same principle is applied to tech like the Apple air-tag. RX and TX data are controlled by a separate molecule at this stage.
@@kevindegenaar it's fascinating. Many thanks for answering.
They can read and write. Wet hard drive. Magnetogenetics
This mean we can be telepathic. If our dna is a antenna. This means many of us could be receptive or sensitive to income frequency through space and time. Giant waking receivers.fantastic news.
this is interesting too wonder how we could make these work for people?
WOW! The HST/JWST of proteins! Biology often gets overlooked, but so much progress since my last class in 1969! Glad I don't have to take it now, seems like quantum mechanics to me these days!
One step closer to becoming the Borg!
The background of this video has many scientists marvelling at either left-handed DNA or DNA without a major groove...
Wouldn’t it be more accurate to call it a sensor rather than an antenna?
Is the fluorescent light information made by a molecule like fluorine or something added or where does this fluorescence come from?
Hi Chris. The energy of the light (a photon) striking the fluorescent molecule raises an electron to a higher energy level. The fluorescence is the light released when the electron falls back to a lower energy level.
When you hit 1 millions subs I’m gunna loose my shit. You deserve it
955K, Cool man, hope you are gonna have a wonderfull party with 1M :)
Could any of the longer lengths of light be used in the nano world? It would be neat if there's anything secret or undiscovered in it
Interesting , very , interesting .🤔
Damn! And I thought the 2.4Ghz SMD antennas from some Express LRS receivers were tiny! 😬
Yep. And, these are sensitive to 5G freqs. 😇
@@svenmorgenstern9506 5G stands for 5th Generation, and still operate between 2.4 to 4.7GHz, just like 4G and other standards do. 5G tech is all about all of the underlying data processing and routing tech, and not the wavelength of transmission.
I used to make wave tech devices for all kinds of physics, bio and medical research, like microwave spectrometers... at 47GHz an antenna can be printed in nm scales on a circuit board, or a hair like (much thinner) filament embedded in Teflon (A better microwave conductor than air). The big hurdles with miniature anything is structural integrity, fault tolerance, and longevity.
@@Bob-of-Zoid Search for the Express LRS then, dude. You're going to like it!
It's an open project of a radio link for rc. They use 900Mhz/868Mhz and 2.4Ghz, your choice. People fly with wings with those for more than 10km of distance... And you can make all the hardware at home if you want to. Or you can buy it from any brand producing hardware for it (and there are many already). You know?
But, well... I'm suspect to talk about flying FPV, because I have depression since 1992 and I always spent weeks happy after flying just for a few minutes.
@@MCsCreations I built an RC plane, and a boat as a kid, and loved it. Now I build and repair guitars in my own shop, and have three hands full, but it is indeed up my alley. I have always loved to tinker and build stuff. I have never had a job that didn't involve being creative, and it is a very good medicine for depression; Been there too.
Sooooo... interesting topic...
(I might have to see the video again to fully grasp the subject,,,)
the thing looks to me more like a SONAR... but...
?how the reception of the feedback is measured in a DNA-antena?
is mechanical, electric, photo-signal... ?
Thanks again for making this subjects available (and comprehensible) wonderful person...
Always awesomeness
bio computers. with great power... -keep it up Anton!
this makes more effective, the modeling of the vast permutations of chemical reactions not even yet observed. over time, these observed interactions in nature, at this temporal detail, can now build more accurate computer models (predictors and tools) of general chemistry. truly groundbreaking, and a bit scary to be honest.