Drugs of Abuse (Mechanism, Intoxication, Withdrawal, & Associations)

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  • čas přidán 29. 05. 2024
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Komentáře • 153

  • @DirtyMedicine
    @DirtyMedicine  Před 3 lety +228

    Didn't have a lot to talk about with LSD, so I dropped that one from the video so that you can focus on high yields only.
    EDIT: since people are asking for completeness sake:
    -Know that LSD is a 5HT2a agonist (increased 5HT activity)
    -Know that LSD produces both synesthesia (i.e. somebody touching your arm makes you hear sound) and depersonalization
    -For inhalants, know that the onset is generally rapid and it causes nystagmus, diplopia, tremor, and respiratory depression. The buzzword is a rash between the upper lip and nose.
    -For Bath Salts, think typical PCP presentation but prolonged.

    • @tarun278roxx
      @tarun278roxx Před 3 lety +11

      Thank your Dirty ! Could you make a video on Highest Yield Topics in USMLE Step1 which one must never leave before taking the Exam. 😊✌

    • @VIVI1337
      @VIVI1337 Před 3 lety +5

      Love how you said "dropped" in reference to the acid, pretty sure that one flew over everyone's head lol!

    • @DrZip
      @DrZip Před 3 lety +1

      Don't forget Ketamine (Dissociation & formerly used as a cat tranquilizer).

    • @cahyasatixoxo7207
      @cahyasatixoxo7207 Před rokem

      IMO a better way to think of the synthetic cathinones like bath salts, flakka or mephedrone is to compare them to high dose methamphetamine or cocaine but with even more agitation and psychotic presentation.

    • @Moosemoose1
      @Moosemoose1 Před 8 měsíci

      If you could add Management for intoxication/withdrawal for the psych shelf that would be great!

  • @jannmikoingelrabagogamingc6012

    Timestamps for each drugs of abuse:
    @2:16 Alcohol
    @15:04 Opioids
    @18:54 Benzodiazepines
    @21:17 Cocaine
    @24:02 Methamphetamine
    @27:49 Phencyclidine (PCP)
    @32:05 MDMA (Ecstasy)
    @35:14 Marijuana

  • @cailinoconnell6981
    @cailinoconnell6981 Před 3 lety +320

    Ben wants it to happen more frequently and Barb wants it to last longer is the best mnemonic ever made. You’re a rock star, Dirty!!

    • @ibraheemalma
      @ibraheemalma Před 2 lety +1

      Where does it come from? Because I see that this mnemonic further needs another mnemonic to memorize it 🤦‍♂️
      I memorized it just by associating the z sound in benzo with the c in frequency, whereas barbiturates and duration both don't have such sharp sounds

    • @ibraheemalma
      @ibraheemalma Před 2 lety

      @@KKK-rc6rk idk what that means

    • @ibraheemalma
      @ibraheemalma Před 2 lety

      @@KKK-rc6rk I get it
      Barbi durate
      Creative 👏
      But I thought you were trying to explain dirtymedicine's mnemonic for me, (barb wants it to last longer or sth like that)
      I have my mnemonic too you know, benZo= frequenCy= they are similar in the sounds, these sharp letters ( c z s...)
      Where as barb and duration are free from that.
      Your mnemonic is easier though
      Oh all these details, what am I talking about 🥲😂🤦‍♂️

    • @ashlitty
      @ashlitty Před 2 lety +15

      @@ibraheemalma lol its a sexual, gender stereotypical reference. ben = guy and barb = girl

    • @shaunascholl6692
      @shaunascholl6692 Před 2 lety

      @@KKK-rc6rk zw wa-×-0

  • @KatieMinckler
    @KatieMinckler Před měsícem +5

    I'm not even a med student nor do I intend to be, but I still find your videos incredibly informative and reasonably easy to follow. I have become frustrated trying to find videos on these topics that are concise, unbiased, and stand up to scrutiny. There's something comforting about learning from the same source as other med students, even if I do need to skip over the minutiae or mnemonics here and there. Thanks for doing what you do.

  • @carolineb133
    @carolineb133 Před 2 lety +45

    A really good mnemonic for pupil size in opiates vs cocaine: make a fist for the O and then a letter C with your hand --> Opiates with closed fist (pupil constriction) and Cocaine with open fist (pupil dilation). I don't remember where I heard but it's saved my life on multiple occasions 😭

    • @carolineb133
      @carolineb133 Před 2 lety +10

      I always forget that heroine is an opiate --> think of Zendaya's A1 performance in Euphoria S2 for opiate withdrawal (abdominal pain and SO MUCH yawning)

  • @xaaboopinkly
    @xaaboopinkly Před 3 lety +38

    Huge thanks sir! Your videos are really one essential part of my studies, and I’m sure of thousands of other medical students too..

  • @hasanbattla2805
    @hasanbattla2805 Před 3 lety +15

    This is amazing! I've gotten a lot of questions on LSD and some on inhalants but the process of elimination def helps!

  • @raeasher590
    @raeasher590 Před rokem +4

    you're the best online tutor ever!! please never stop with these vids!!

  • @francidouglass8338
    @francidouglass8338 Před 2 lety +1

    I LOVED the rapid review at the end thank you so much!!!

  • @kushangeeweerawardhane9645
    @kushangeeweerawardhane9645 Před 2 lety +23

    Thank you so much Dirty Medicine 😊
    I passed my exam (Australian Medical council Examination)Your videos were of immense help 🥰🥰🥰🥰🥰

  • @hammadali7594
    @hammadali7594 Před rokem +1

    I love you man. I hope and sincerely wish you succeed in every walk of life. Whatever you dream of, may you get it all. Blessed be.

  • @TheRabidbunnies
    @TheRabidbunnies Před rokem +5

    Love this video! I think if you re-ded this for whatever reason in the future, including common names for some of these drugs would be helpful - mostly thinking about heroin/opioids because I've seen NBME use that name a lot instead of opioid and I didn't know they were the same drug class at first!

  • @Waseem.210
    @Waseem.210 Před 8 měsíci +1

    I loved the slides talking about the “associations” in alcohol
    Genius!!! God bless

  • @saurabhpatel3576
    @saurabhpatel3576 Před 2 lety +8

    Thankyou dirty! I watched this video yesterday and got 6 questions from this video on my exam today🔥

  • @amaranathl9864
    @amaranathl9864 Před 2 lety +2

    You are amazing in explaining complex subject in simple way great and thanks

  • @adeelsajid995
    @adeelsajid995 Před 3 lety +2

    This was much needed! Thank you!!

  • @susanalsaeede3277
    @susanalsaeede3277 Před 2 lety +1

    Thank you so much, a good recap.

  • @haminater100
    @haminater100 Před 3 lety +12

    Hey Dirty i just want to firstly say thank you for everything you do and I hope God keeps blessing you man. Can you make a video on micturation because its another HY topic that seems to confuse me. Thanks again

  • @saroaltinoglu3123
    @saroaltinoglu3123 Před 2 lety

    this was an amazing presentation for the EPPP

  • @rshnpkalam5879
    @rshnpkalam5879 Před 4 měsíci

    “What’s up man? you want some?” -will help me remember Ecstasy well! Thank you for doing this video and also for the laugh.

  • @BeMihret5909
    @BeMihret5909 Před 3 měsíci

    Thank you and God bless you!

  • @mariajahan6137
    @mariajahan6137 Před 2 lety +1

    Hats off to you!!!

  • @drsandipchaudhari8636
    @drsandipchaudhari8636 Před 2 lety +9

    Hey dirty ..Sir I got my 2ck score..It’s 245.Thank you very much

    • @nooral4315
      @nooral4315 Před 2 lety

      good job! which dirty medicine videos are best for step2?

    • @drsandipchaudhari8636
      @drsandipchaudhari8636 Před 2 lety +1

      @@nooral4315 frankly speaking I got 2 questions from Neurocutaneous disorders video too..drugs of abuse…ethics videos too useful

  • @tonichihab8394
    @tonichihab8394 Před 2 lety +7

    That hippy imitation was gold😂😂😂😂

  • @ramyasmruthismruthi1623

    this video is so so helpful .......i cant thank u enough , hope atleast i earn 1 to 2 points from this topic .....thank u so much , please continue doing this great work

  • @AbubakarUmarMusa
    @AbubakarUmarMusa Před 2 lety

    Thank you you’re a life saver🙏

  • @tobymichaels8171
    @tobymichaels8171 Před 5 měsíci

    Undoubtedly valuable info here for improving test scores. Just don't mistake these high-yield test answers for the actual presentations you'll see in clinic.

  • @nicolebonet6119
    @nicolebonet6119 Před 2 lety

    This is SO helpful. Thank you!!!

  • @BOXHEADBLADEFACE
    @BOXHEADBLADEFACE Před 3 lety +5

    Thank you so much.
    Dirty is there advice you can give, on How to approach a question, when you have zero Clue what it could be ? I know "they are telling you the answer" in the question, but many times even when I highlight the right info, for some reason I still cant figure it out. Your test bank videos have been a huge help, and I have finished uwrold, but the idea of coming across a tricky question on the real exam (in 7 days) is really freaking me out.

  • @deepalipimpale309
    @deepalipimpale309 Před 8 měsíci +1

    Hello , thank you so much for every single video you have made so far . Please make videos on case history taking and all the disorders mentioned in DSM 5 TR

  • @ashlengovender8888
    @ashlengovender8888 Před 3 lety +1

    Just started my pharmacology block 👍🏾

  • @TheFarmerSJ
    @TheFarmerSJ Před rokem

    Thank you so much for this video!!!

  • @haseebali2164
    @haseebali2164 Před rokem +1

    Man you are a true life saver

  • @vanessanwaiwu3163
    @vanessanwaiwu3163 Před 3 lety

    Thank you soooo much Dirty!!!!

  • @drhasancb4
    @drhasancb4 Před rokem

    Thank you very much. ❤

  • @mimisworld732
    @mimisworld732 Před 10 měsíci

    Thank you so much for sharing your knowledge. This video is so far the best and love the way you explained.

  • @umarahisrar2480
    @umarahisrar2480 Před 2 lety

    Soooooo much respect!

  • @sindhiashyras8800
    @sindhiashyras8800 Před 2 lety

    thank you soooooooooooooooooooooo much, very clear with lot of insight

  • @rasolove3
    @rasolove3 Před 2 lety +1

    Thank you so much ☺️

  • @assourali1255
    @assourali1255 Před rokem

    Thanks again for your help

  • @godlistenmsuya5828
    @godlistenmsuya5828 Před 2 lety

    Thank you so much!

  • @zzkzkzzkzkzk8945
    @zzkzkzzkzkzk8945 Před 2 lety +10

    Not even a med student but this was a good video

  • @eydanniks8733
    @eydanniks8733 Před 5 měsíci

    Thank you!! ❤

  • @mohannedjamal9471
    @mohannedjamal9471 Před 3 lety +1

    thank you

  • @shreyajoshi1647
    @shreyajoshi1647 Před 10 měsíci

    Amazingly explained

  • @phytx01
    @phytx01 Před 2 lety

    Thank you for this amazing explanation, Can you please make a video for Renal Tubular Secretions and Diuretics. because they're really very confusing.

  • @draanchal1
    @draanchal1 Před 2 lety

    Loved it .thanks

  • @yourremarkablyaveragepal781

    I died at the OpioYAWWWWning hahaha. Thanks, doc!

  • @pacifiquebusiness
    @pacifiquebusiness Před 3 měsíci

    Thank You 🥰

  • @aceyshari
    @aceyshari Před 2 měsíci

    Amazing videos.. useful to prep for my PMHNP exam

  • @yolandalimcangco3164
    @yolandalimcangco3164 Před 5 měsíci

    Great presentation!

  • @nurulsyhrh82
    @nurulsyhrh82 Před 10 měsíci

    thank you so much for this!! ❤

  • @Mohammad-xe2qw
    @Mohammad-xe2qw Před 3 lety

    Thanks thanks thanks❤️🥰I am crazy about pharmacology🥰🥰🥰

  • @gavinbutler6243
    @gavinbutler6243 Před rokem

    Thanks for the facts

  • @nehadharap700
    @nehadharap700 Před měsícem

    Man, I like your videos even before I watch it

  • @faezehabbasi1740
    @faezehabbasi1740 Před 2 lety

    Great
    thanks a lot

  • @studyturtle7159
    @studyturtle7159 Před 2 lety

    Never forgetting bzd n barb mechanism!!😂😂 🔥

  • @heenagujral244
    @heenagujral244 Před 7 měsíci

    So sweet that you say love u at the end, we love u too

  • @nooblysm5556
    @nooblysm5556 Před rokem

    Thanks for the vid!

  • @michaelgoldstein8516
    @michaelgoldstein8516 Před 2 lety

    Love it. Loved the Austin Powers cameo lol.

  • @shushri2894
    @shushri2894 Před 3 lety +1

    🙏🙏Indirectly he taught for one Indian exit Exm. (ths r main topics) . Must needed Thank you so much dirty medicine

  • @oraena5526
    @oraena5526 Před měsícem

    your videos are awesome!

  • @wwhuang8178
    @wwhuang8178 Před 10 měsíci

    such a great video

  • @ibraheemalma
    @ibraheemalma Před 2 lety +4

    I memorized it just by associating the z sound in benzo with the c in frequency, whereas barbiturates and duration both don't have such sharp sounds

  • @nikygreen9473
    @nikygreen9473 Před 2 lety

    THANK YOU

  • @DirtyMedicine
    @DirtyMedicine  Před 2 lety +2

    Please JOIN my CZcams membership, where you pay $4.99 a month to support the channel and in exchange you get the cool Dirty Medicine logo which will appear next to your username whenever you comment! Click the "JOIN" button under the video, or click the first link in the description of the video (the one that says "SUPPORT/MEMBERSHIP"). Thanks

  • @bobkennedy6382
    @bobkennedy6382 Před 3 lety

    THE BEST!

  • @notpinhead3514
    @notpinhead3514 Před 2 lety +1

    "Ahh thank you"
    What a goddamn legend.

  • @LittleAyishie
    @LittleAyishie Před 10 dny

    the love u at the end 😭💕

  • @tasneembashir2733
    @tasneembashir2733 Před 7 měsíci

    Can the stored Ecstasy be detected by lab test? Talking about the hallocinigen persistence symptoms

  • @MS-ns4ki
    @MS-ns4ki Před 11 měsíci

    I’m about to redo the entire curriculum and CC my boss as well as my colleague so everybody can see all the hard work so I’m going to do - 💋

  • @SuperHahahaha123
    @SuperHahahaha123 Před 2 lety

    I had a Uworld that said cocaine withdrawal can also cause vivid dreams btw. Dirty you're the best btw.

  • @majdmuhannad7254
    @majdmuhannad7254 Před 3 lety

    you're the best

  • @priscilla9872
    @priscilla9872 Před 8 měsíci

    love you too! ty

  • @jahlanijackson9807
    @jahlanijackson9807 Před 3 lety +2

    Cool!

  • @joewilliam1183
    @joewilliam1183 Před 2 lety

    M8 i laugh si hard on that "Whats up man, you want some??"

  • @nabeela6467
    @nabeela6467 Před rokem +1

    Can you include part 2 which is next step in management (eg, tx)?

  • @cob7839
    @cob7839 Před 13 dny

    Love you too 🥺

  • @migs6869
    @migs6869 Před rokem

    Clutch vid dirty thanks man !

  • @christopherlauw1570
    @christopherlauw1570 Před 2 lety

    You're a legend

  • @DrZip
    @DrZip Před 3 lety

    @DirtyMedicine, Marijuana Hyperemesis relief with heat sounds to me like Uhthoffs Phenomena in MS; perhaps the heat is impairing saltatory conduction / neuronal stimulation in a similar fashion, thereby providing relief with MHS, where it would provide pathology in MS?

    • @DirtyMedicine
      @DirtyMedicine  Před 3 lety +1

      www.ncbi.nlm.nih.gov/pmc/articles/PMC3576702/pdf/nihms353647.pdf

  • @hazelswords8573
    @hazelswords8573 Před 2 lety

    Hey do you have any idea why the yawning happens with heroin withdrawal. I can never find the answer even Google ???

  • @benfilla2954
    @benfilla2954 Před 2 lety +1

    Are you using the term 'withdrawal' the same the whole way through? For example with alcohol you are meaning the effects that a chronic drinker experiences when they stop, however I feel like some of the symptoms you are explaining for later drugs seem like they might be more like the 'come down' after using the drug.

    • @DirtyMedicine
      @DirtyMedicine  Před 2 lety +4

      correct - i am using the term to describe those concepts interchangeably for the sake of simplicity; there is a difference between coming off of a drug vs. neurochemical withdrawal

  • @pinnacleatom
    @pinnacleatom Před rokem +1

    Any concerns about multiple drug abuse and the inconsistencies in presentation ?

  • @ronefana4015
    @ronefana4015 Před rokem

    Thx❤

  • @yeyo101
    @yeyo101 Před 3 měsíci

    BenZodiaZepines associate the Z of benzos with Frequency which is measured in Hertz (Hz)

  • @preethi7751
    @preethi7751 Před 2 lety

    GOLD!

  • @Mo-ez3hs
    @Mo-ez3hs Před 3 lety

    ur amazing

  • @mohsinabid9420
    @mohsinabid9420 Před 2 lety

    whatsup man you want some was the best part 😅 it reminded me skinny from breaking bad

  • @faba7786
    @faba7786 Před 8 měsíci

    YOU'RE THE FREAKING GOAT

  • @p.kallas6692
    @p.kallas6692 Před 5 měsíci

    I have a decompartment left arm. I am having big doses oxicodon. My son died then i got ssri, bensodiazapam and iktovril sleeping pills. But i never been this tired of living.

  • @junaidbhat468
    @junaidbhat468 Před 2 lety

    How can right sided endocarditis cause janeway roth spots etc they are part of left side endocarditis

  • @guns-n-tuberculosis3467
    @guns-n-tuberculosis3467 Před 11 měsíci +1

    PCP is one of the only drugs of abuse to feature nystagmus! Like horizontal and vertical in addition to rotary. Don't let that trip you up like it did me :O

  • @GREGhere15
    @GREGhere15 Před 3 lety +3

    I love you Dirty med! :)

  • @supernova5107
    @supernova5107 Před 3 lety +1

    You left out LSD my favorite one of all

  • @bernadettearellano5698
    @bernadettearellano5698 Před 3 měsíci

    What could come back as a pos Methamphetamine, false positive, even on a retest? Is it possible?

  • @gracewaithaka9382
    @gracewaithaka9382 Před rokem

    Thank you!

  • @TheAklingos
    @TheAklingos Před 2 lety +6

    Or you can call them "Barbidurates" for duration 🤙

  • @sm4887
    @sm4887 Před 3 lety

    ❤️❤️❤️❤️

  • @peterjuhl-yh3ne
    @peterjuhl-yh3ne Před 6 měsíci

    How about verbal abuse of people? Are there any examinations.