Bronchodilators Part 1: Principles of Respiratory Airflow and Development of Selective Drugs

With immunomodulation covered, it's time to dive into pharmacology of pulmonary activity. First up is bronchodilators. These address resistance in the bronchus and bronchioles that impede respiration, such as with asthma, emphysema, and bronchitis. This can be achieved through beta-2 adrenocepter agonism and muscarinic receptor antagonism. What are these receptors, what are their endogenous agonists, and how do bronchodilators interact with these receptors?
Script by Michael Keith
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[@waelfadlallah8939]

It's just amazing the wide scientific coverage this channel provides 🤯

[@mjjoe76]

This helps explain why over the counter asthma medication made me twitchy and jumpy.

[@SergeiTheAnarch]

Great job Prof! Excellent job explaining SARS for drug development, it's a very common method.

[@AdeptALot]

Great job prof.!!!!! I enjoyed a lot and waiting for ur next in pharmaco

[@archivist17]

Thanks Dave. This is a great explanation.

[@pedroequis9396]

Good job Professor Dave ! Looking forward to your next class.

[@shadowmax889]

B3 is also found in the wall of the bladder, the detrusor muscle, decreasing its contractility. B3 receptors are the target for the drug Mirabegron and is indicated to treat overactive bladder

[@rogebel11]

Thanks!

[@aashishgautam9217]

Bht bdia ustad ji

[@yaseenkhoso05]

Good 👍

[@CGFillertext]

Very informative!

[@_tim4e]

Hey, does anybody know any good websites that provide information about the pharmacodynamics, pharmacokinetics, etc. of specific drugs and have a large database(except for Wikipedia)?

[@sciencenerd7639]

wow!

[@SubjectSigma18]

Just a couple of days I had to make an essay related to my asthma to my p.e teacher

[@-JA-]

👍👏

[@nirmalmishra6404]

Sir kindly make a video on Fajan's rule.

[@desmond3828]

immune system!!!

[@nebulan]

Some of these graphics make my lungs hurt... it's been a bad fall for my asthma :(

[@bazinga1831]

okay

[@Donsomebody]

I get bad during the winter due to the cold air. All the best for your asthma treatment

[@germangoblin3203]

Could you pls make a video about EHS (electromagnetic-hypersensitivity) and 5G?

[@eatshitlarrypage.3319]

No such thing. 5G uses frequencies within 4.10 * 10^8 Hz to 7.125 * 10^9 Hz and 2.425 * 10^10 GHz to 7.1 * 10 ^ 10 Hz. Visible light, for comparison, is 7.5 * 10^14 Hz to 4.2 * 10^14 THz. If people were sensitive to 5G, just being in a lit room would be overwhelming agony. There are no direct dangers to people from 5G. That being said, there are some other legitimate issues it causes, such as causing interference for water vapor detection methods (used in weather tracking), as well as issues with airplanes. Photons without enough energy to ionize atoms pose no threat.

[@germangoblin3203]

@@eatshitlarrypage.3319 yeah I meant he should debunk it

[@homosapien5684]

Please do a series on differential equations

[@eatshitlarrypage.3319]

Psst: czcams.com/play/PLybg94GvOJ9ELZEe9s2NXTKr41Yedbw7M.html

[@homosapien5684]

@@eatshitlarrypage.3319 thanks, but this doesn't have differential equations

[@livingcodex9878]

おはようございます

[@janefrost1856]

Good morning to you from the UK, I wish you well