What Is Psilocybin (Magic Mushrooms) & What Are Its Effects? | Dr. Andrew Huberman
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- čas přidán 28. 11. 2023
- Dr. Andrew Huberman discusses the chemical and structural similarities between psilocybin and serotonin, their effects on the brain, the specific role of the serotonin 2A receptor in psilocybin's actions, and its potential therapeutic benefits in treating mood disorders and inducing neuroplasticity.
Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab podcast.
Watch the full episode: • How Psilocybin Can Rew...
Show notes: www.hubermanlab.com/episode/h...
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I started microdosing 2 months ago and with the first dose I felt soooooo much better that I don't feel like I need therapy anymore. It was like the dark cloud that had been hanging over my head my entire life just evaporated. That doesn't mean I don't have bad days or that life is perfect now but it's so much better.
just curious what your dose is like?
@@edunsavagevery low: 0.03g or 30 mg every other day
Do you have to keep using it?
What was your dosage?
dosage pls?
Magic mushrooms literally saved my life
No more additions
No more depression
No more anxiety
& No more sertraline 🙏🍄❤️
Where do you get these from? Guessing you're in the uk? I'm prescribed sertraline
How did you use it? Full trip or microdosing? How did you get rid of SSRI? Is there any protocol you used or did you freestyle? Thanks in advance
Are you referring to this shrooms?
@hasnasoliman6722 hey,
Yes I starting microdosing psilocybin whilst very slowly tapering down on sertraline, until I completely stopped sertraline. I also take a heroic dose once a month . Its great 👍
🎯 Key Takeaways for quick navigation:
00:02 🍄 *Psilocybin's Chemical Similarity to Serotonin*
- Psilocybin, a tryptamine like serotonin, closely resembles serotonin in structure.
- Serotonin, a neuromodulator, influences various neural activities, including mood, pleasure, and motivation.
- The similarity between psilocybin and serotonin raises questions about why psilocybin induces specific experiences despite their structural likeness.
01:29 🧠 *Serotonin's Functions & Receptors*
- Serotonin's diverse functions involve mood regulation, pleasure, motivation, and more.
- Its impact on numerous serotonin receptors leads to a wide array of effects in the brain and body.
- Understanding serotonin's role highlights the complexity of its influence on daily life and mental health.
04:24 🧩 *Psilocybin's Interaction with Serotonin 2A Receptor*
- Psilocybin's specificity in binding to the serotonin 2A receptor drives its distinct effects.
- Activation of serotonin 2A receptors triggers changes in neural circuitry, leading to mood improvements and relief from certain disorders.
- The selectivity of psilocybin in targeting this receptor explains the excitement surrounding its therapeutic potential.
07:17 🔄 *Comparing Psilocybin and SSRIs*
- Psilocybin's efficacy in treating depression surpasses that of SSRIs in some cases, sparking attention.
- Contrasting outcomes between psilocybin and SSRIs underscore the importance of receptor specificity in their effects.
- Understanding the selectivity of psilocybin for the serotonin 2A receptor elucidates its therapeutic potential compared to SSRIs.
The key takeaway is that science does not fully understand serotonin but since serotonin is also influenced by the gut, proper nutrition is the beginning of overall health, not a psychedelic that’s main purpose for many is to obtain a “trip” or to patent for profit 💊 🤑
I stoped drinking, and eating crap food. I started sleeping better and being happy inside. All by eating magic mushrooms. No wonder they don't want us taking these. It would end soo many jobs and pharmaceuticals. 🎉
I absolutely agree with you
Mushrooms played a pivotal role in my journey to conquer addiction, and l've never experienced a greater sense of self-control.
I can honestly say psychedelics experience was probably one of the most profound and beautiful collection of moments I have ever had
Awesome episode. What's his background? The way he says ligand is funny to me as a chemist.
i absolutely love when we discuss pharmocology. Escpecially the pharmocology of naturally occuring substances.
Cyanide and arsenic are also naturally occurring. Are you going to take those to get a trip? At least it’s not a Tide pod. 🤒 🧺 The synthetic version of vitamin B12 is derived from a form of cyanide. It’s a slow form of malnutrition. Pharmaceuticals are not always the smartest tool in the shed.
jude shrumz
On IG
Sells
great talk Andrew, what are the dosages that you speak of ? is this a once off dose or is it a micro dose on a routine basis?
In my experience, therapy is best done frequently for a few days, normal dose. Then give it a long break to reset tolerance. Minimum two weeks
He goes into detail about your questions on the full podcast about psilocybin
hey doc i was wondering if you could help me understand nicotine replacement pouches i live in canada and the ones that are available to me are called zonic they are like the zyn pouches in the usa my concern is that they say they are food safe and okay to swallow the biproduct of it witch is in your syliva i belive these to be hard on your liver and kidneys what do you think
hey there man im not an expert but i would not recommend swallowing that stuff. if you are experiencing this alot, chances are you arent doing it right or that it has been in your mouth too long. though i have forgotten them in for over an hour before and do not have any issue with the biproducts seeping into my mouth. try to keep it as dry as possible when its in
What is it that psilocybin does? Not how does it work, or what does it do to the brain. What effect does it have, that the person taking it experiences? You're just saying in this video that it may relieve depression, and may relieve obsessive compulsive disorder symptoms. Why then do you call it a "journey" to take it? How can there be something called a "journey" if there are no detectable experienced effects worth mentioning? If it "improves mood" how can a person tell that their mood is improved by it? What's the experienced effect?
This is only a 10 minute clip of a two hour discussion, so I suggest you check out that video
I was sooo sick before mushrooms lol
Ive been out of my supply since early Feb. worst feeling in the world. It’s a hard crash like getting off of SSRIs. For someone like me who has many mental health challenges like major depression, anxiety, CPTSD. This is equivalent of getting off your meds.
I feel so connected, alive, full of motivation, able to control impulse and hyperactivity. Moderate my diet, stick to my routines. Require less sleep and get so much more done, when I am micro-dosing.
It’s a shame I have to wait for it to be legal. Alas. I’ll be regrowing my own supply again. There is nothing I’ve ever had (especially from the VA) that can compare to the terrific effects of microdosing.
I’ve also macro dosed and got through some hefty trauma stuff. I can’t do therapy without it. The memories way too deep, and the trauma triggers send me into a spiral without them. So, north spore all in one bag, and inoculate the world for the win.
@👉Crystal growstores
That's the mycologist's page name.
His on
ln$ta, not website.
I'll recommend you look up the mycologist for quality supplies and guide on dosage. They got the best stuffs
This is the problem with the authoritarian Christians who want to control everything you do.
very interesting video. With some of the recent research into the causes of Long Covid (which Ive been dealing with for 19 months) low levels of serotonin and cortisol in the gut are being looked at as a possible cause of some of the LC symptoms. I have done some micro dosing during this LC nightmare but perhaps its time to up the dose a bit. Any one else out there dealing with LC?
Tinnitus tremors pains but after COVID vaccination
45 yr old male
Developed daily Vagal Afib/
Daily MM 1g dosing has stopped afib completely
I can’t find a single piece of information related to this
Research has shown psilocybin to have great potent to treat a range of anxiety and behavioral disorder. -
Mushrooms has been a God to me thanks to my buddy who has been guiding me through this experience
Dude on Instagram
@mycotinny
6:53 what kind of doses?
jude shrumz
On IG
Sells
Im micro dosing right now and its the ONLY medicine that has ever ever helped CPTSD 🍄💯🍄 Thank you! Calcium deficiency is the cause of all depression and parathyroid/thyroid in the throat right.
@iwilifred6471 yes please. I agree, the mushrooms are totally divine.
hi Andrew
Hi
How to get them?
I'll hook you up with this mycologist whose been my guide for some time. His got LSD, DMT, MDMA, MUSHROOMS, CHOCOLATE BARS, GUMMIES, ETC..
@chaposhrooms..
Depends on where you are. You can also just grow shrooms
Psilocybin saved my life
Mushrooms has been a God to me thanks to my buddy who has been guiding me through this experience
Dude on Instagram
As mycotinny
what about cat food?
Where can I buy magic mushrooms?
I order mine from Charlesmyco.
He's on instagram.
I live in Brooklyn NY and is very difficult to get around here. So intend to order my products from his store.
@@lilianparle4822 I live in California 😞
@ Charlesmyco
Can we go on a field trip
First class🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄🍄
I got some psychedelic products from an online store
from
cruise_mycologist
Talk about wearing sweatpants reverse for better sleep
You put your feet in the bottom of the legs of sweatpants to sleep
Like a Sleeping bag for your legs?
I guess it could help in winter for ppl with cold feet or circulation problems
Clickbait
This was the most boring video on shrooms I've ever seen. Even your background was boring.
today im so high it was fun to watch😮
youtube celebrity doctors are the best