CLOSTRIDIUM DIFFICILE COLITIS, Causes, Signs and Symptoms, Diagnosis and Treatment.
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- čas přidán 7. 08. 2024
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Chapters
0:00 Introduction
1:11 causes of CLOSTRIDIUM DIFFICILE COLITIS
2:52 symptoms of CLOSTRIDIUM DIFFICILE COLITIS,
3:10 Diagnosis for CLOSTRIDIUM DIFFICILE COLITIS,
3:52 Treatment for CLOSTRIDIUM DIFFICILE COLITIS,
Clostridium difficile colitis is an inflammation of the colon that is caused by an infection with the clostridium difficile, a bacteria found throughout the environment- in the soil, air, water, food products such as processed meat, and even human and animal feces.
• The bacteria release multiple toxins that attack the lining of the colon and cause severe damage to the colon itself.
• Infections with the clostridium dificile happen everywhere in the world.
• In 2011, about 453,00 cases of Clostridium difficile infections occur in the United States resulting in about 29,000 deaths.
• Clostridium difficile colitis can result in complications such as pseudomembranous colitis (patches of severe inflammation and pus in the colon), a hole in the colon, dehydration, toxic megacolon (where the colon is unable to expel gas and stool), and even death.
CAUSES
Clostridium difficile colitis is caused by an infection with the Clostridium difficile bacteria.
Clostridium difficile bacteria is spread by spores found in feces. These spores can spread to food and other surfaces and objects when people who are infected don’t wash their hands properly. These spores can persist in a room for weeks or months, where a person can then get infected after touching infected surfaces and then unknowingly eating or rubbing their face with their hands.
C. difficile infection is mostly associated with hospitals and other health facilities, where workers are more likely to come in contact with it and pass it from room to room
It is also associated with recent antibiotics use. The intestine usually contains many bacteria that keep it healthy and prevent the body from infections. When antibiotics are taken to treat an infection, these drugs may destroy normal, healthy bacteria alongside the bacteria for which the antibiotics were taken in the first place. Without enough healthy bacteria, C. difficile can quickly grow in the intestine where they release toxins that attacks the lining of the intestine, causing inflammation in the colon.
Risk factors may include:
• Older adults in health facilities, especially if they are taking antibiotics.
• Taking antibiotics
• Having serious illness such as inflammatory bowel disease, certain cancer
• Having a weakened immune system
• A previous infection with the bacteria
• Recent gastrointestinal surgery
SYMPTOMS
• Diarrhea, containing blood or pus
• Weight loss
• Fever
• Nausea with or without vomiting
• Abdominal pain and cramping
• Abnormal heartbeat, if you become dehydrated
DIAGNOSIS AND TREATMENT
The condition is always suspected in people with diarrhea who have recently taken antibiotics, or who develop diarrhea a few days after hospitalization.
To confirm a diagnosis, a sample of your stool is collected to be tested for the bacteria. This is done by testing for the toxins that the bacteria produce or by detecting its DNA.
A colonoscopy may also be carried out to examine the inside of your colon to look for areas of inflammation.
AAbdominal X-ray may also be recommended to provide images of the colon. These can detect the presence of complications associated with the condition.
TREATMENT
Treatment options include:
• Certain antibiotics that target C. difficile including metronidazole, fidaxomicin, vancomycin. These antibiotics keep C.difficile from growing.
• For people with certain complications, surgery may be carried out to remove the affected portion of the colon. This might be the only option in such cases.
For people with repeated cases of the condition,
Probiotics which are organisms such as yeast and bacteria, which help restore a healthy balance to the intestinal tract may be recommended.
A fecal transplant can also be done. In this procedure, stool from a donor is placed into your colon. The healthy bacteria in your donor’s stool helps to get rid of the bacteria and restore health to your colon. This treatment option is not yet approved by the FDA as it is still under study.
To prevent the condition, always wash your hands.
It's super difficult to get a fecal transplant. There are many hoops to jump through, and ins doesn't pay for it. If you can even find a doctor that will do it.
Nice
This took my mothers life. Worser than covid.
I’m so sorry to hear this. I don’t know what covid is like but I’ve been dealing with recurrent c. Diff for 5 years now. And bless your mother, I’m sorry she had to deal with it and may she rest in peace.
I’m so sorry 🙏🏽🙏🏽🙏🏽🕊️
I've had this infection twice, my colon is clear but I have scarring in my colon for life and i have a high high chance to get it again. And when I had it I had to be quarantined for 2 weeks at a time. Flagyl antibiotics were the force against the disease, but if I take any other antibiotics I have an increased chance of getting it again which honestly sucks. The worst thing about getting once or twice is that you'll have this for the rest of your life. My case since I've had it twice, I gotta deal with the disease for the rest of my life. This disease is nothing to mess with, it's really really serious. It can cause terrible complications if left untreated. This messenge is a warning! Great video, nice and professional! You've got yourself another subscriber!
Sorry about the experience and thank you for sharing
what else besides flagyl in your opinion helps?
I have stomach pain every day and diarrhea almost every morning. I don’t have it all day. Sometimes it’s more than once if I ate something bad. I know I have stomach problems but whenever I go to the doctor they just try to say I have acid reflux or ibs without actually testing anything.. it’s frustrating living with stomach pain everyday all day.
@@TheRealBlackMagicAre you still dealing with this? I am having recurrent c. Diff too maybe we can help each other. Take care of yourself
@@gingerentertainment7628 I just get stomach pain and feel bloated and burp air a lot lately
Hello, can acute use of prednisone and topical steroids cause a reduced immune state that may cause C. Diff to thrive?
Topical steroids don’t have systemic affect tho
Hey Medical Centric, I want to ask you a question as I feel like I’m fighting for my life with this right now. Any advice to give someone who just got off a round of Vancomycin, I feel like it’s coming back worse. It’s felt pretty terrifying and intense I barely function. I’m going back to my doctor next week but this has been happening for years now and I feel like they will never be able to get rid of it. Are they missing something? Answer if you can and thanks either way
Unfortunately once you have had it once, its likely to come back. However i recommend trying flagyl and vancomycin together for your next round of antibiotics and if it keeps coming back, ask if a faecal microbial transplant is worth your time. C.diff sucks so dont think your going crazy just keep trying. I really hope you get better soon, keep your head up
@@JackJones-jm5hv thank you man that means a lot. I’m going to have to try that. I’ve been wanting to give up hope lately and I appreciate the kind words and I hope you continue to stay healthy
I am sorry that you have a recurring CDI so long. My mother has it more than five months. She was three times in the hospital. Every time she got Metrodinazol and Vancomycin. The fourth time she got Fidaxomicin but unfortunately it came back. Now the doctors want a transplant. It is such a severe disease. I wish you all the best
@@anap8715 Thank you for your kind words. I’m sorry that your mother has to deal with it too. You’re right it’s a horrible disease but we can beat this. I think she could do a transplant or whatever would help her get rid of it. I know it just seems like the antibiotics don’t get rid of it. The hospital told me it is one of the most resistant bacterias
@@gingerentertainment7628Of course you will beat it. I wish you a speedy recovery.
Do any of y'all know how you contracted CDiff?
Antibiotics
Mines feels like c diff. Antibiotics 3 years ago. And then I drank raw milk to cure. Bad mistake. Stomach went nuts. 1 year dairy free was a big help and going off gluten is helping also
Well, I'd consider getting a fecal transplant.