Structural Activity Relationship (SAR) of Opioids

Activity of opioids is greatly related with various groups at different positions with either increasing or decreasing effects on both analgesic activity and potency. Here we will discuss such important SAR of opioids along with examples.

[@wongwaitsun]

I am a pharmacy student, this video really help me in exam, big big thank you

[@egpat]

Glad to hear that. All the best.

[@sharanabasavarm6787]

Sir am pharmacy student this helped me a lot to understand the concept clearly thank you very much sir

[@ketankuralkar3606]

Thanks for making my concepts crystal clear 🙏

[@leenasa2286]

you're really the master of chemistry, THANK U SO MUCH

[@muhammedadel1241]

from Egypt. Your video came in handy Thanks a lot.

[@oluwasijibomiosiyale3433]

Thank you so much for this..
Keep up the good job.

[@sofialevashoff]

Thank you for the material! Do You have any suggestions on where can I read more about variations of 17th position?

[@karthikbanka6083]

Sir actually I'm not interested in subject but after ur explanation I hava some interest thank you very much sir this is helpful for me

[@152.muhammaddawood2]

Vip ustaad

[@yusurnaseer1454]

great summary it is really help me thank u

[@AG-xq3ut]

Hila diya be, quality

[@lauryjerry1566]

This is the best teaching ever

[@kusumagompa2381]

Sir very informative session and it's helpful for my exam

[@joshuaduke1284]

Great material!

[@smk1821]

Hloo sir ..this is amazing...
Please do make SAR of antihistamines
Fluoroquinolones
Antidiabetics structure

[@egpat]

Sure. Thank you.

[@smk1821]

What is this wanna be friends comment?
Is that a bug sir
I often see everywhere

[@onyinyechukwuval-neboh7418]

Very helpful!

[@lazara5172]

Amazing you made my assignment so easy and understandable. God bless you

[@egpat]

Glad it was helpful! Thanks for watching.

[@DrGopi-oq2lc]

Thank you
It was so helpful 😊

[@skittless3949]

how is naloxe 7,8 dihydro when no saturation/ double bond is present?

[@muhammadsaman8100]

Thank you 💙

[@skittless3949]

Why is it that the other acetyl group on position 6 in heroin does not also get metabolized to possibly become hydrolyzed and become less potent?

[@merhawikahsay9622]

thank you

[@raneembaaqeel4716]

Thank you sir

[@Shahnawazkhan-hh8er]

Thank you sir 👍👍

[@roz8189]

Very good teaching video (Thank u)

[@egpat]

You are welcome

[@AnanaSIsho]

Best explanation, thank you sir!!

[@egpat]

Most welcome!

[@ruchitamath9298]

The video is great and helpful 👌😊will u please upload SAR of diuretics....... please 🙏🙏 that will be great.... please

[@sarabagheri5135]

I've learned a lot. Thank u.

[@egpat]

You are very welcome

[@hassanselo2668]

What a videooo !!!!!!!! 🔥

[@amarenderreddy5108]

It's very informative

[@egpat]

Thanks for liking

[@pritijagtap1366]

Helpful video

[@egpat]

Glad to hear that

[@abhijitkarmakar2343]

Sir plzzz SAR related or bhi vides banao PLZZ sir 🙏🙏🙏 in sab videos hi waja se hamare exam me bohat help ho rahahe so plz sir

[@TMH12]

👏👏👏👏👏

[@j.venkateshkumar9005]

Super sir

[@SouvikNagYT]

Sir , I'm grateful to you...for your lecture, I got understand this complex thing just night before exam...thank you so much sir ❤️

[@egpat]

You are most welcome

[@kusumagompa2381]

Sir very informative and its very helpful for my exams sir

[@egpat]

You are welcome

[@frankiegargoyle7783]

so morphine w like 11carbons on the 17?

[@egpat]

Morphine has simple methyl group at 17th position. So it acts as mu receptor agonist.

[@frankiegargoyle7783]

right, but assuming you replaced that, yielding 11carbons on the nitrogen how does chain length or various substitution effect agonist potency?

[@girtmcdirt2000]

Opie AIIIIGH

[@grahambrown1980]

I used to study this stuff a lot around 20 years ago. Pretty cool. 💉💊😎🧪🧑🏻‍🔬

[@abdullahnajmabed3125]

thank you