FDA approval of TRYVIO - aprocitentan

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This video describes the approval of TRYVIO, which contains aprocitentan as its active pharmaceutical ingredient. TRYVIO is approved to treat hypertension in patients taking other antihypertensive drugs. TRYVIO was approved by the U.S. FDA on March 19, 2024. The sponsor of the NDA was Idorsia Pharmaceuticals. Aprocitentan is an endothelin receptor antagonist. Efficacy, ADME/PK, and key safety risks of TRYVIO are discussed.
This video was created for academic purposes. The creator of the video has no financial stake in the drug sponsors or relationship with the FDA.

[@neof.m7517]

informative

[@joshyu1124]

Would be interesting to know its solubility and permeability