PHYSIOLOGY SHORTS: Aerobic exercise training-induced alteration of gut microbiota

In this Physiology Shorts, Masataka Uchida and Professor Motoyuki lemitsu (Ritsumeikan-Global Innovation Research Organization, Ritsumeikan University, Kusatsu, Shiga, Japan) discuss their recent paper: Physiology Aerobic exercise training-induced alteration of gut microbiota composition affects endurance capacity.
Read more in The Journal of Physiology:
'Aerobic exercise training-induced alteration of gut microbiota composition affects endurance capacity.'
Motoyuki Iemitsu et al.
601 (12), pp. 2329-2344
physoc.onlinelibrary.wiley.co...
Transcript:
Hi, my name is Masataka Uchida and I am first author in this study. This study corresponding author is professor Motoyuki Iemitsu. Our research group has been investigating inter-organ crosstalk as a mechanism of exercise and diet effects.
Today I am going to tell you about our recent study in The Journal of physiology.
In this study, to clarify whether aerobic exercise training-induced alterations in the gut microbiota affect physiological adaptation by increasing endurance capacity, we carried out two experiments in combination.
First, we found that antibiotic treatment attenuated the increase in endurance performance and metabolic regulators in skeletal muscle after aerobic exercise training.
Next, we demonstrated that aerobic exercise training altered gut microbiota composition, and two gut microbes were associated with endurance performance and muscle metabolic regulator.
Finally, we clarify gut microbiota transplantation from exercise-trained mice augmented endurance performance and metabolic regulator levels in recipient skeletal muscle, despite the absence of aerobic exercise training.
Our data suggest that the gut microbiota altered by aerobic exercise training is involved in the augmentation of endurance capacity and muscle mitochondrial energy metabolism.
Thank you for taking to time to learn more about our study published in The Journal of Physiology. The full paper was published in Volume 601, Issue 12. Please contact professor Motoyuki Iemitsu, if you need.

[@mattelfesso]

Interesting concept!