In this video, I decide which molecules are most cringe! Grimace is the best. / thatchemist Community Discord - / discord Second Discord link if the first one is borked - / discord
@@That_Chemist my field of work is just as removed from chemistry as one could imagine, but i bingewatch your videos nonetheless. idk, there's something in your narrative flow that gets me every time, even when i don't understand the topic. you're like "the jdodkfjsoic acid is very good for asdfging the 2,3,5-onium-qwertyade" and i'm like HELL YEAH BROTHER GIMME MORE OF THAT that's talent. you're talented. with all the hard work you're putting in, the content is extremely good. it deserves way more subs than you have now, and i'm so glad i found you early!! lots of love ^^
@@fjlkagudpgo4884 I just told That Chemist this same thing the other day!!😅 I regularly fall asleep with a chemical terminology stream of consciousness running through my mind. And after hearing all the chempolation stories, if I ever work at a university (or even a high school, for that matter) I have been thoroughly scared off from having a classroom or office ANYWHERE NEAR the lab 😂😬 👨🔬👩🔬⚗️⚛️💥
@@mcawesomestudio I'll be motivated to be more serious about PPE if I'm ever in a chem lab again, even high school ones, for sure. I'd like to not go blind or lose feeling in my hand, 5hank you 😅😂
As a man who forgets most of his chemistry from school; looking at this is how a Lovecraft protagonist must have felt laying eyes on the elder gods and their servants.
Imagine spending years of your life devoted to studying advanced chemistry, to then say fuck it and invent a whole new molecule purely because it looks like a stick man. Legends
It’s funny because this was also Tour. I just graduated from Rice and he taught me orgo freshman year, he’s super proud of the Nanoguys (actually called nanoputians to reference Gullivers Travels) and still talks about them at the end of his lectures
I've been known to disinfect things with Na2H3CO6 (sorry, can't find the subscripts on my smartassphone) - a more or less shelf stable source of high concentration H2O2. The way all those oxygens are bound in the crystal lattice looks kind of cursed.
Love him or hate him, nanokid is getting bismuth, technetium, helium, and sulfur. Side note, my favorite application of gen x is poisoning large rivers in a certain east coast US state.
"It turns out it's actually used in sunscreen. It's good at reflecting UV light, and it's also good at absorbing both UV-A and UV-B. So in my opinion this one is super duper cringe." based skin cancer enjoyer
Bibrockathol? For eye infection? Looks like some madman was trying to make super tear gas old school style.. I use capsaicin cream for muscle ache and itchyness , it often gets in my eyes... I can laugh that off. I remember the old-school pepper spray & tear gas that had bromine in it's formula, and WOW that stuff made a habanero to the eye feel like a warm hug by comparison. If I saw that formula on a bottle of something a doctor wanted to put in my eyes, I'd say "Are you trying to cure my eye infection by encouraging me to rip my own eyes out Saw style?" Are you sure that's for use en vivo? Not for transplants of something. I so got to look it up now!
Funny story about that. A colleague wanted to use phenacyl-bromide (alpha-bromoacetophenone) for synthesis. Before purchase he had to affirm that he was not going to use it as a chemical weapon. During use a small quantity of it must have got aerosolized, making it extremely difficult to keep eyes open in the lab. Wikipedia states that it is a powerful lachrymator and I can attest to that.
As a non chemist I've been binge watching all these tier lists and have no idea why they are cursed or cringe, and seeing how cursed and cringe seems interchangeable in this list makes me even more confused lol
Ah chemistry, the discipline where structures with a lot of circles in hexagons make me giggle. Also, what do you call the carbon allotrope that’s like graphene, but all of the carbon bonds are double?
Nice shout out to Mirex. One of the "Dirty Dozen" persistent organochloride insecticides. Nasty amounts of chloride. The Diels Alder Endosulfans are really wicked too. Used to all be perfectly legal OTC.
PFAS are also hellish to work with from an experimental standpoint. They're so good at being non-stick that they'll often drip right out of our pipettes while we're trying to test them. I think a PFAS video as a whole would be super interesting. If you need any perspective from someone who is doing research on their effects, I'd love to share what I can.
Fun anandamide fact: one of the metabolites of Tylenol is a compound called am404 which looks and acts a lot like anandamide and is at least partially responsible for the pain relieving effects of the drug
Oh WOW. I had to go look this up and yeah, they're doing human trials. If I ever get a bad case of 'rona again and end up taking this, my jimmies will be substantially rustled.
Have carbons with more than 2 oxygens can be a good thing. Propylene carbonate and dimethylcarbonate are both great solvents to work with. Safe enough that they aren’t even considered VOC’s in the USA and much less restricted in the EU. Carbon pentoxide and carbon hexoxide are cringe enough that I would not go in the same room as them.
Once again nature proving to be the superior chemist when it can create molecules that would have most of us just go 'NO' when looking at them let alone trying to synthesise them.
TIL: Keeping rings from being happy is cringe. EDIT: If there's anything that raises more red flags than five nitrogens bonded to one another, it's five oxygens bonded to one another. None of those look like they want to exist.
As someone that barely knows any chemistry: all of these look like they dont really wanna be there, and all look great to give cancer, especially the iodine one idk why iodine is all that of a good leaving group but it just wants to leave
Iodine is such a good leaving group because of its size. Its bond with carbon is very weak because the bond length is so long, and its anionic form is very stable because of the high volume available to the extra electron.
Imagine something like "ChemComic" where the most curaed molecules bully the most cringe molecules. And there will be all sorts of different molecules and they would different relationships between them and would be the most nerd comic ever. That would be so awesome. OMFG MÖBIUS CARBON BELT imagine if carbon klein bottle existed
GRIMACE FOR LIFE!!!! I don't think I'll ever get tired of these. I absolutely love the tier lists because it inspires me to do more research after learning about something new, and exciting I've never heard of or had the chance to work with. I'm not in school for organic chemistry yet. I'm still working on a cybersecurity masters program at the moment. However, once I'm done with this I'm definitely going back for O-Chem. No. There's absolutely nothing anyone can do or say to change my mind. I want to do something very specific.
Analytical Chemist here. Another cool application for TEMPO is as a free radical initiator for the sequencing of peptides via mass spectrometry. Basically it allows for the generation of fragments that you wouldn’t otherwise see using traditional collision induced dissociation and therefore can lead to better sequence coverage.
This isnt the video, but I recently watched one of your videos and you mentioned how toxic brake cleaner is, and my anxiety started snowballing. The amount of times ive washed my hands with the stuff is actually terrifying. My father is the one one told me it was fine to do so, but Ive never questioned whether or not he was right. Fuck me, was he wrong.
Huh; I'd thought (based on the smell of at least one brand) that brake cleaner was mostly acetone with some modifying ingredients. Upside: acetone is, while a bit more toxic than ethanol, relatively normal for your body to deal with (you've got proper metabolic pathways to deal with it and have some endogenous generation of the stuff) _and_ relatively effective at removing grease from hands. It can dry your hands out pretty badly, but so would the brake cleaner.
TEMPO analogues are really useful for NMR and EPR spectroscopists for biochemistry. Very useful for Paramagnetic Relaxation Enhancement experiments and for determining the dynamics of proteins.
haven’t taken a chemistry class in 3 years. I don’t understand or know why but your videos are extremely interesting and engaging and I’ve been hooked on them.
I *LOVE* your justifications for what precisely makes a molecule cringe, as well as to which degree it is cringe relative to the others!! This comment is quite cringe, but idgaf! 🤣👍
Are you going to also do a tier list of based molecules? And since did one on cursed molecules you could also do one on blessed molecules (or even blursed molecules).
I feel these tier list videos are fun, but would be more fun and rewatchable if you put the things in order from F to S, to build up the fun during the video and easy finding afterwards ;)
Nanopution has only 3 fingers..humm... Grimace, a shout-out to Tom(ex&f)? Covered vi-heart too with the bestagons... Makes me wonder what references I missed??
This is one of my favorite channels, because where else can you hear the line: “Grimace? Grimace is based. Show some love for Grimace in the comments. You know what isn’t based? Tetradioxin.”
I've worked with lots of alkynyl iodides in grad school. They are actually not that unstable if you have a moderately electron-donating group on the other end of the alkyne, like alkoxy, amide, sulfonamide, and phosphonamide. Like (Bn)(Ts)N-C≡C-I kind of structure. Isolable as oils or waxy solids that are best kept in the fridge but fine to handle at room temp in air. One interesting feature of these compounds is their 13C spectra. The carbon with the iodine attached has a signal more upfield than TMS -- around -20ppm as I recall! So realizing iodopropynyl butylcarbamate is used as a preservative in consumer products didn't surprise me that much; it's just a bit "interesting" to me. Also worth mentioning is IPBC is rated "highly toxic" by inhalation. Though being non-volatile and with typical usage below 0.1% (and prohibited in aerosol-type products) it poses zero inhalation hazard in pratical use. Also, I did undergead research in the nanokid lab. But by the time they had finished that particular project and all I did was making precursors for nanocars. The very first experiment I did was recrystallizing a 50-gram batch of NBS from hot water.
Calicheamicin, is that related at all to erythromycin? Cause that’s the first thing that popped up in my head when you were talking about Calicheamicin.
Not only are superbenzene infusions in carpathite quite pretty, they also fluoresce under UV light. The naturally occurring gamma form glows green/yellow, but the beta form glows orange.
Those phenyltriazole style things are pretty common in uv absorbers. Not sure why, maybe the H is transferred to the nitrogen and lets it dissipate energy that way; or maybe it helps to keep the whole thing planar? Not sure. Anyway a very common motif in many of the tinuvins and what have you. The more expensive version is a series of UVA's called the hydroxyphenyl-S-triazines; same principle but more so. Arguably less cursed looking ;) EDIT: TEMPO-style motifs are actually used quite often in HALS and NOR-HALS as photostabilizers.
I've seen this channel come up a few times in my feed, this is the video that's going to make me binge watch every video here.
Glad to hear it :)
@@That_Chemist
my field of work is just as removed from chemistry as one could imagine, but i bingewatch your videos nonetheless. idk, there's something in your narrative flow that gets me every time, even when i don't understand the topic. you're like "the jdodkfjsoic acid is very good for asdfging the 2,3,5-onium-qwertyade" and i'm like HELL YEAH BROTHER GIMME MORE OF THAT
that's talent. you're talented. with all the hard work you're putting in, the content is extremely good. it deserves way more subs than you have now, and i'm so glad i found you early!! lots of love ^^
@@fjlkagudpgo4884 I just told That Chemist this same thing the other day!!😅 I regularly fall asleep with a chemical terminology stream of consciousness running through my mind.
And after hearing all the chempolation stories, if I ever work at a university (or even a high school, for that matter) I have been thoroughly scared off from having a classroom or office ANYWHERE NEAR the lab 😂😬 👨🔬👩🔬⚗️⚛️💥
@@mcawesomestudio I'll be motivated to be more serious about PPE if I'm ever in a chem lab again, even high school ones, for sure. I'd like to not go blind or lose feeling in my hand, 5hank you 😅😂
@@fjlkagudpgo4884 Yess omg sometimes I have no idea what he's talking about but I'm so hyped anyway lol
As a man who forgets most of his chemistry from school; looking at this is how a Lovecraft protagonist must have felt laying eyes on the elder gods and their servants.
Haha
Or how a Lovecraft protagonist felt when looking at a black person, knowing Lovecraft.
Bro 😂😂
@@scritoph3368 im in agreement with lovecraft there
@@TS-jm7jm so... youre... racist trash? Are you either misunderstanding the joke, or just saying the quiet part out loud?
Imagine spending years of your life devoted to studying advanced chemistry, to then say fuck it and invent a whole new molecule purely because it looks like a stick man.
Legends
Saddest paper I have ever read, next to Tour's nanocar. Shame he never managed to get nanoguy into nanocar.
It’s funny because this was also Tour. I just graduated from Rice and he taught me orgo freshman year, he’s super proud of the Nanoguys (actually called nanoputians to reference Gullivers Travels) and still talks about them at the end of his lectures
Absolute Gigachad
@@FleshWizard69420 cringe.imagine not wanting to make deadly nerve agents for a living
Looking forward to the "which molecules are the most based" tier list
“Which bases are based?” Already exists!
@@That_Chemist diethynylbenzene dianion
Those molecules that can't drawn clearly in 2D are so cringe that I don't even know which atom connects to which at the first glance.
Yeah
"This can go into B tier" *puts it into A tier*
"You don't ever want to see carbon with more than two oxygens."
Carbonate wants to know your location
I've been known to disinfect things with Na2H3CO6 (sorry, can't find the subscripts on my smartassphone) - a more or less shelf stable source of high concentration H2O2. The way all those oxygens are bound in the crystal lattice looks kind of cursed.
bicarbonate ion has 3 oxygens on a carbon.
Or carboxylic acid, cornerstone group of life itself.
@@Mikemk_arboxylic acid is -COOH that's 2 oxygen's
Grimace is a giant anthropomorphic taste bud who is constantly hugging children (squishing them onto his taste receptors.) That's pretty cringe.
Grimace is the Joe Biden of maccers lmao
@@That_Chemist i have NO idea if that's supposed to be a compliment or an insult
@@That_Chemist Based
Grimace is another synonym for cringe. Maccy’s knows what they’re doing
@@That_Chemist you and E&F decided on a running gag when you collab'd?
Love him or hate him, nanokid is getting bismuth, technetium, helium, and sulfur.
Side note, my favorite application of gen x is poisoning large rivers in a certain east coast US state.
"It turns out it's actually used in sunscreen. It's good at reflecting UV light, and it's also good at absorbing both UV-A and UV-B. So in my opinion this one is super duper cringe."
based skin cancer enjoyer
Isobenzotriazoles are cringe AF
Which molecules are the most metal?
Edit: Grimace is the most metal.
🟣🤘
That chemist should do a sulflower total synthesis. From methane and sulfur obviously.
This sounds like very yellow chemistry, and it's making me nervous.
Ah Grimace, fukin' love him
Grimace is love grimace is life
man, I fucking love Grimace
Only Australians understand
@@JackFrawley101 Well i'm Polish but still chuckled because of Explosions&Fire. I have absolutely no idea what Grimace is.
Chuck him on the grimace pile on the dashboard
If molecules could talk, Dodecaphenyltetracene would definitely say “BE NOT AFRAID”
Grimace E&F fan eh?
I have Tom in a mini discord with some other chemtubers 🤙
@@That_Chemist yall should do a video on yellow chemistry
Bibrockathol? For eye infection? Looks like some madman was trying to make super tear gas old school style..
I use capsaicin cream for muscle ache and itchyness , it often gets in my eyes... I can laugh that off. I remember the old-school pepper spray & tear gas that had bromine in it's formula, and WOW that stuff made a habanero to the eye feel like a warm hug by comparison.
If I saw that formula on a bottle of something a doctor wanted to put in my eyes, I'd say "Are you trying to cure my eye infection by encouraging me to rip my own eyes out Saw style?"
Are you sure that's for use en vivo? Not for transplants of something. I so got to look it up now!
Funny story about that. A colleague wanted to use phenacyl-bromide (alpha-bromoacetophenone) for synthesis. Before purchase he had to affirm that he was not going to use it as a chemical weapon. During use a small quantity of it must have got aerosolized, making it extremely difficult to keep eyes open in the lab. Wikipedia states that it is a powerful lachrymator and I can attest to that.
I like when you resize and expand the molecules first. I'm often on mobile and this makes them much easier to read and see the structure.
Agreed!!
A user suggested it and I started implementing it - thanks :)
This kinda is "most cursed molecules tierlist 2.0"
Tbh, I don't know that much about chemistry, but I find these videos pretty chill and cool to watch
That is exactly what this video started out as
As a non chemist I've been binge watching all these tier lists and have no idea why they are cursed or cringe, and seeing how cursed and cringe seems interchangeable in this list makes me even more confused lol
Ah chemistry, the discipline where structures with a lot of circles in hexagons make me giggle. Also, what do you call the carbon allotrope that’s like graphene, but all of the carbon bonds are double?
You’ve heard of NanoPutians, now get ready for the nanocar!
Grallene?
@@adiaphoros6842 When they're made in Russia, they're called nanoputins.
@@adiaphoros6842 WW
This video has convinced me the line between cringe, cursed and intriguing is rather fine
Nice shout out to Mirex. One of the "Dirty Dozen" persistent organochloride insecticides. Nasty amounts of chloride. The Diels Alder Endosulfans are really wicked too. Used to all be perfectly legal OTC.
PFAS are also hellish to work with from an experimental standpoint. They're so good at being non-stick that they'll often drip right out of our pipettes while we're trying to test them.
I think a PFAS video as a whole would be super interesting. If you need any perspective from someone who is doing research on their effects, I'd love to share what I can.
you have my dream job, i want to go into organofluoro chemistry when i graduate! i think theyre so fascinating.
Fun anandamide fact: one of the metabolites of Tylenol is a compound called am404 which looks and acts a lot like anandamide and is at least partially responsible for the pain relieving effects of the drug
Interesting
So Tylenol is in a way a prodrug for a weak analog of Thc?
Another OTC 'gateway' drug... :)
I wonder if Tylenol will make weed last longer
@@MandrakeFernflower If anything you’d think it would make it slightly less effective because it will compete for the binding site
Tom would also agree that Grimace is F, because he loves grimace too.
I’m p sure I’ve read somewhere that TEMPOL was being researched as a treatment for covid. Eating a radical is ultra cringe
Oh WOW. I had to go look this up and yeah, they're doing human trials. If I ever get a bad case of 'rona again and end up taking this, my jimmies will be substantially rustled.
Tom from E&F will need a private moment with Grimace being in the video caption.
Missed opportunity defiling it and giving it a yellow tan for Tom
HOW DARE YOU - GRIMACE IS THE FURTHEST THING FROM TRASH TIER YELLOW CHEM
@@That_Chemist i was hoping he'd make grimace explosive but that would require defiling grimace and we all fuckin love grimace
Jawsamycin is named after the movie. The cyclopropyls look like shark teeth.
As someone who does a lot of EPR, I take gripe with your ascertion that unpaired electrons are cringe😤
I thougth you said ERP and was very confused
Have carbons with more than 2 oxygens can be a good thing. Propylene carbonate and dimethylcarbonate are both great solvents to work with. Safe enough that they aren’t even considered VOC’s in the USA and much less restricted in the EU.
Carbon pentoxide and carbon hexoxide are cringe enough that I would not go in the same room as them.
Based
Once again nature proving to be the superior chemist when it can create molecules that would have most of us just go 'NO' when looking at them let alone trying to synthesise them.
Exactly
Well, nature has a few million more years of experience in the field. Give us some slack here.
TIL: Keeping rings from being happy is cringe.
EDIT: If there's anything that raises more red flags than five nitrogens bonded to one another, it's five oxygens bonded to one another. None of those look like they want to exist.
Looks like someone is trying to make a new rocket fuel!
As someone that barely knows any chemistry: all of these look like they dont really wanna be there, and all look great to give cancer, especially the iodine one
idk why iodine is all that of a good leaving group but it just wants to leave
Iodine is such a good leaving group because of its size. Its bond with carbon is very weak because the bond length is so long, and its anionic form is very stable because of the high volume available to the extra electron.
does a metal technically count as a "molecule" like one huge molecule of course the atoms are covalently bonded they have metallic bonds
It just works
You could also say that e.g. diamonds are huge molecules as well as some polymers.
Imagine something like "ChemComic" where the most curaed molecules bully the most cringe molecules.
And there will be all sorts of different molecules and they would different relationships between them and would be the most nerd comic ever.
That would be so awesome.
OMFG MÖBIUS CARBON BELT
imagine if carbon klein bottle existed
That would be amazing
You would need an extra dimension... Maybe there is a subatomic analog...
When you cover PFAS, you could also inform (at least yourself) about Organoclays, which could potentially remove this shit from water
Waiting on a chemist to synthesise Grimace and world peace will be restored
12:52
>"we probably should put it in the B tier"
>puts it into A tier instead
11:20 bruh i accidently read that as "Morbius Carbon Nanobelt" and assumed he was joking loll
It’s morbin time (I morbed everywhere)
@@That_Chemist i was so shook when i found out that you had morbed everywhere (The morb was too much to handle) Oh and also Grimace is great
brb getting an organic chemistry PhD just to do macaroni art with functional groups
Hahaha
If I ever have my own group, I will totally include meme compounds in all of my scopes
Glad to see a diyne in your list. I used to work in a lab where we polymerized diynes using a Cobalt-60 radiation source.
Cool!
It's nice to hear you talk about pfas, my sister did a lot of her research on it
I would definitely watch a video on it
Grimace gang! Favorite thing to find in my water is a purple guy with a smile :)
Looking forwards for the pfas video! nice work!!
13:44 in Poland triangle pointing down = toilet for men, circle = toilet for women 😅
Although standard signs are most commonly used nowadays. Probably due to confused tourists.
Omg two of my favorite chemists sharing Grimace memes across the world. Are we getting another Explosions and Fire crossover?
That chemist should make a compound where all hydrogens in a benzene is replaced with an azide group.
GRIMACE FOR LIFE!!!!
I don't think I'll ever get tired of these. I absolutely love the tier lists because it inspires me to do more research after learning about something new, and exciting I've never heard of or had the chance to work with. I'm not in school for organic chemistry yet. I'm still working on a cybersecurity masters program at the moment. However, once I'm done with this I'm definitely going back for O-Chem. No. There's absolutely nothing anyone can do or say to change my mind. I want to do something very specific.
Analytical Chemist here. Another cool application for TEMPO is as a free radical initiator for the sequencing of peptides via mass spectrometry. Basically it allows for the generation of fragments that you wouldn’t otherwise see using traditional collision induced dissociation and therefore can lead to better sequence coverage.
This isnt the video, but I recently watched one of your videos and you mentioned how toxic brake cleaner is, and my anxiety started snowballing. The amount of times ive washed my hands with the stuff is actually terrifying. My father is the one one told me it was fine to do so, but Ive never questioned whether or not he was right. Fuck me, was he wrong.
Yeah a lot of Dad advice is actually pretty bad
Glad to hear there are fewer people washing their hands with brake cleaner
Huh; I'd thought (based on the smell of at least one brand) that brake cleaner was mostly acetone with some modifying ingredients. Upside: acetone is, while a bit more toxic than ethanol, relatively normal for your body to deal with (you've got proper metabolic pathways to deal with it and have some endogenous generation of the stuff) _and_ relatively effective at removing grease from hands. It can dry your hands out pretty badly, but so would the brake cleaner.
Morbius was so popular they named a chemical after the movie. What a time to be alive!
Wait until you hear about Molecular ORBitals…
Carbon hexoxide looks a bit like a round bottom flask? Does anyone else see it?
Yeah
TEMPO analogues are really useful for NMR and EPR spectroscopists for biochemistry. Very useful for Paramagnetic Relaxation Enhancement experiments and for determining the dynamics of proteins.
and NMP polymerisation
haven’t taken a chemistry class in 3 years. I don’t understand or know why but your videos are extremely interesting and engaging and I’ve been hooked on them.
Automatically liked for "Hexagons are the bestagons" ++
Do a boomer molecule tier list. Housane has to be the s tier boomer molecule…back when it was affordable
Lmao
Pulling out all the stops with the references! Love it
I *LOVE* your justifications for what precisely makes a molecule cringe, as well as to which degree it is cringe relative to the others!!
This comment is quite cringe, but idgaf! 🤣👍
I refuse to believe the Grimace resurgence has nothing to do with Explosions and Fire's latest video... xD
Oh it does
But it has even more to do with how great grimace is
Is Grimace in the thumbnail because of Explosions & Fire's McDonald's video recently? I saw your comment on it, too!
Grimace is just so great
Are you going to also do a tier list of based molecules? And since did one on cursed molecules you could also do one on blessed molecules (or even blursed molecules).
I have a based bases tierlist
@@That_Chemist I'll have to check that out.
5:50 re: josamycin, I just read a couple days ago that they're tweaking a very close molecule to turn it into a high energy-dense biofuel
I love your content, as a chem student this is very helpful for my adhd.
as someone with ADHD, I completely understand
TCDD shout out too. Organo-Chloride was my lifelong passion of study. Must admit I'm on Fluorides now way more scary. Good stuff sir always A+
Tom from E&F loves grimace should have invited him again
Bisoctrizole looks like two 3rd form Friezas about to dab each other up
I feel these tier list videos are fun, but would be more fun and rewatchable if you put the things in order from F to S, to build up the fun during the video and easy finding afterwards ;)
Can you do some more ChemDraw stuff? Would love to see some tricks to draw more complicated structures.
I’d prefer if I worked with them to do a sponsored video at some point
Nanopution has only 3 fingers..humm...
Grimace, a shout-out to Tom(ex&f)? Covered vi-heart too with the bestagons... Makes me wonder what references I missed??
If anyone wants to learn more about PFAs and a particularly bad scandal involving them, I wholeheartedly recommend the movie Dark Waters.
It’s a great video for non-experts but there are several issues that have come to light in terms of accurate PFAS detection
TIL all my doodling with models in Ochem was actually producing nanoputian molecules lol
This was one of those episodes I watch with pubchem in the next tab
Haha
This is insanity, and so unbelievably preposterous. You just earned a subscriber.
This is one of my favorite channels, because where else can you hear the line:
“Grimace? Grimace is based. Show some love for Grimace in the comments. You know what isn’t based? Tetradioxin.”
:)
Cool reference to the Ex&F video
Can you do one on peptides?
Semax / Selank come to mind as an example
the Moebius Carbon Nanobelt made my goblin brain go "oooh shiny"
I've worked with lots of alkynyl iodides in grad school. They are actually not that unstable if you have a moderately electron-donating group on the other end of the alkyne, like alkoxy, amide, sulfonamide, and phosphonamide. Like (Bn)(Ts)N-C≡C-I kind of structure. Isolable as oils or waxy solids that are best kept in the fridge but fine to handle at room temp in air. One interesting feature of these compounds is their 13C spectra. The carbon with the iodine attached has a signal more upfield than TMS -- around -20ppm as I recall! So realizing iodopropynyl butylcarbamate is used as a preservative in consumer products didn't surprise me that much; it's just a bit "interesting" to me. Also worth mentioning is IPBC is rated "highly toxic" by inhalation. Though being non-volatile and with typical usage below 0.1% (and prohibited in aerosol-type products) it poses zero inhalation hazard in pratical use.
Also, I did undergead research in the nanokid lab. But by the time they had finished that particular project and all I did was making precursors for nanocars. The very first experiment I did was recrystallizing a 50-gram batch of NBS from hot water.
Oh hell yeah, another Grimace.
just listening to you say right off the bat "and today were gonna be deciding which molecules are the most CRINGE" Is so funny to me 😂😂
Calicheamicin, is that related at all to erythromycin? Cause that’s the first thing that popped up in my head when you were talking about Calicheamicin.
I swear, bisoctrizole looks like a dude trying to look into the 5th dimension.
Love the cgp grey reference lmao
Which one was that?
The title for this video is genius
Haha
Wow, never thought I'd see a biocide I work with for consumer products in a tier list
Not only are superbenzene infusions in carpathite quite pretty, they also fluoresce under UV light. The naturally occurring gamma form glows green/yellow, but the beta form glows orange.
Is that Grimace thing a reference to a recent E&F video? :D
You bet baby
I’m liking hearing about the chemicals used in cosmetics! I want to make my own cosmetics and seeing what I should avoid is cool
i like the callback to the E&F video
Most polyunsaturated fatty acids found in nature have uncongegated double bonds. That's just the typical structure.
True
"Grimmace is awesome"... I feel like a certain specific explosive Australian man would agree 🤔
Those phenyltriazole style things are pretty common in uv absorbers. Not sure why, maybe the H is transferred to the nitrogen and lets it dissipate energy that way; or maybe it helps to keep the whole thing planar? Not sure. Anyway a very common motif in many of the tinuvins and what have you.
The more expensive version is a series of UVA's called the hydroxyphenyl-S-triazines; same principle but more so. Arguably less cursed looking ;)
EDIT: TEMPO-style motifs are actually used quite often in HALS and NOR-HALS as photostabilizers.
Nice shout out to Explosions and Fire channel :D
Check it out - I got him to add grimace to the thumbnail
I got that Grimace reference. I love you.
Do a video on diethynylbenzene dianion. That molecule is crazy.
The content i subscribed for
Glad to hear it :)
shots fired at grimace, tom's gonna come for you lmao
Starting a Grimace cult with E&F
Disappointed that cycloparaphenylene isn't on this list.
This video was absolutely awesome.
That diphenyl whatever looks like a crochet pattern.