Evidence of inflammation in the pain and fatigue of Gulf War Illness

This is a quick review of a paper just released from our laboratory. It shows that the pain and fatigue of Gulf War Illness appear to be related to inflammation and immune dysregulation. The paper is not "open access" and not available everywhere, but the link is: pubmed.ncbi.nlm.nih.gov/35902...
My apologies for being, literally, unfocused in this video. Sometimes my camera's focus dial misbehaves. Fortunately, I am showing the paper most of the time, so you aren't missing anything.

[@olivertruswell]

Thank you for your hard work! I have ME/CFS and one of your presentations at a conference with Ron Davis a few years back was the first clear evidence that there were physical symptoms going on. I'd been told by doctors that I was severely depressed and it was all in my head. I really appreciate that you're in this field and we're extremely lucky to have a talented researcher like you dedicate a large portion of your career to these groups of illnesses.

[@BRS5]

Thank you Dr. Younger.

[@youngerlab]

You're welcome. We are 2-3 months out from starting clinical trials, so I hope to have more good info soon. - Jarred Younger

[@2short1968]

Thank you for your information. I am trying to use any information to help me understand why and how I feel today. I served with the 82nd Airborne Division during the beginning all the way to the end of the Gulf War. I am always tired with no energy when I came back from the war . I have memory loss that I never had before.....etc.

[@F15CEAGLE1]

SAME.

[@johnmontecalvo1508]

I was diagnosed with Cronic Inflammation, elevated monocytes. Lycolates, and Nuphils for 25 years, of blood work.

[@bernie0748]

Thank you Dr. Younger for this update. As someone who has served in the Gulf War and was diagnosed with autoimmune disease and a host of other chronic illnesses, this Will hopefully be helpful to those of us who have been turned down by the VA for disability multiple times. I look forward to future updates. I am curious to know if the information you have shared with us was also made available to the Department of Defense and the VA?

[@youngerlab]

There is a scientific officer with the DoD that collects the information about GWI research. He is definitely interested in disseminating the information however possible. There probably won't be anything introduced to the VA until there are treatment recommendations. But the DoD is defintely expecting the research to lead to treatments, and the VA would welcome solid treatment recommendations. That is the reason we have been increasing our clinical trial research. - Jarred Younger

[@KittenCasserole]

Congratulations on the publication. Very interesting findings. Thanks so much for your and your team’s hard work. Happy Thanksgiving

[@youngerlab]

Thanks!

[@itguru2037]

I have all these symptoms but never set foot in the gulf. I was in the marines from 1985-1991

[@DeanSmith-ch1ep]

Mefloquine?

[@DeanSmith-ch1ep]

I was never in the gulf. Took Mefloquine in Africa for 5 months. Same sypmtoms

[@itguru2037]

@@DeanSmith-ch1ep I’ll see if they gave it to me

[@itguru2037]

@@DeanSmith-ch1ep are you putting in a case?

[@DeanSmith-ch1ep]

@@itguru2037 not yet. Waiting for a confirmed diagnosis. I was on a peacekeeping mission. No combat. No stress.

[@Star5dg]

Do you do consultations? I have severe cfs, eds - the fatigue is brutal

[@youngerlab]

I haven't been able to do consultations, mainly because I shouldn't give individual advice, and I have to focus on getting several clinical trials running right now. But I will be doing several videos soon with treatment advice individuals can take to their physician to try. - Jarred Younger

[@jimmybrokos4610]

Can you help me?

[@freecat1278]

Oxycodone barely puts a dent in this pain. I don't think ibuprofen is going to cut it.