How does Narcan (naloxone) Work?
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- čas přidán 22. 08. 2024
- How does Narcan (naloxone) Work? Pharmacology for Nurses
Narcan (naloxone) is an opioid antagonist which means it will move any opioids currently sitting in a receptor site - out, and Narcan will take its place to prevent opioids from binding. The opioid that was originally sitting in the receptor site functioned to change the cell activity. Opioid receptor sites can be found in the brain, nervous system, and intestines. The ones we are concerned with here are the ones in the brainstem as when opioids connect to those receptor sites, the drive to breathe decreases.
You may come upon a patient who is breathing very slow or not breathing at all. If Narcan is available, you can administer it. It will not harm someone who has never taken Narcan and it may potentially save a life.
Narcan is given every 2 to 3 minutes if there is no response and in your kit, there will be three doses. If the patient does respond to the first dose, they may wake up agitated because all their pain is back. They should stay awake for 2o to 60 minutes before the Narcan is depleted, leaving the opioid receptor sites free for the opioids that are still circulating to bind. As opioids have a longer half-life, many doses of Narcan are usually required.
As opioids have a longer half-life, we often need to use Narcan more than one time on the same patient.
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When you mention that all of the pain a patient previously had will come back immediately, you should also remind that the patient will be in full-blown opiate withdrawal which is most likely the reason for hostility
Living in Las Vegas I think we need to blast your video on the billboards. Everyone needs to have narcan on hand to help out with the opioid pandemic. Thank you!
I'm inclined to believe with Narcan, the cure is worse than the disease.
You’re the kind of non-judgemental person I feel like would incubate an incredible conversation. Thank you for the video, it was an enjoyable lesson 🙏
😊
When I was in grade 10-12 there was an opioid pandemic. I graduated in 1999, I'm 40 now. And thankfully it never happened to me but it is still happening. I recently picked up a kit from the pharmacy. I hope I never have to use it. Thank you for the video!!
I hope you never need it, but having it is awesome in case you do
It wasn’t half as bad then as it is now. I am 43 I graduated in 98 I don’t remember no opioid pandemic down at all media people did it, but it wasn’t. They weren’t dropping dead like they are now not even close.
What a beautiful video. Thank you for dispelling doubts and questions about a highly stigmatized topic.
Thank you for your comment, and time
This video was so informative. It answered every question I had about naloxone.
Yeah!!!! Stay safe
I'm learning about hypertension so that I can get off the meds. I find your videos very informative. Thank you!
Great! Keep your healthcare team involved.
3 years on this is the only youtube video I can find on narcan's functional mechanishm. Thank you!
You are welcome :)
You diving on top of the patient is badass
Hahaha
I got a Naloxone kit because I go to festivals and other events during the summer and I wanted one handy. (my brother-in-law lost a nephew to a fentanyl OD.) I'm glad I watched your video now I understand a lot more on the drugs work and the responses to expect. Thanks for doing this.
Y Penney - in Ontario
Happy to help :)
I’m usually never into this type of stuff but this was so interesting to me. The biology behind it and the history is really cool. Hopefully I don’t have to use this information in the future 😂
It is pretty cool! Thank you for sharing
Very informative, I’ve always been curious and this in depth explanation has really explained things. I thought your personal experience was interesting as well. 👍
Thanks!
That's a fabulous kit!! In the states, our kits come with only 2 doses, and none of the extras! Gloves, breathing device, etc!
Oh wow! I always find it fascinating how different places do things
@@NurseMinder In Quebec too, only two doses. Thanks for the video!
Very Good Explanation.. Good Job...
Thank you
I overdosed on heroin one time and they put Narcan up my nose. I swear to God when I woke up it was like I had so much energy. I didn’t know why everyone was around me staring at me. It was so crazy, I want to know why Narcan put me into rapid withdrawal. My skin started crawling, I was sweating, it was hell. So I want to know what’s in Narcan that makes someone that overdose is going to withdraw
Thanks for sharing your experience. When Narcan is used, it will look for any narcotic and remove the narcotic from a receptor site. And then Narcan will block that site so the medication cannot find. It is as if you have not taken any medication once Narcan is on board. Problem is Narcan only last for a short time, and then as it dissolves the medication will again connect into the receptor. So it can be a up-and-down ride
No idea how I got to this video but glad I did. Thanks for sharing the info. You are a great trainer too!
This video is priceless! Thank you Nurse!
You are welcome 🙏
It’s crazy what scientist have done
Wonderful job, thank you so much. This may be a silly question....is it possible to give it to bring yourself back? Like as you feel yourself going down. Is that unheard of? You addressed a terrifying, shameful, and secretive subject un~biased with ease in quirky
with ease in a quirky and thorough delivery.
Yes you can give it to yourself. Its one of the benefits of having the kit
Thank you for this more simplicity way to understand Narcan
Peace
*Have a Safe*
*Happy Holiday Season*
👍😉🍀👍😉🍀
Appreciate the feedback. Happy holiday season to you as well
Thank you. So well explained.
💕
Hi Mrs Tammy, I enjoyed watching you explaining Narcan also known as Nalcoxone and how they can be a pain reliever for Opioid.
I found this topic interesting because I am a Human Services major at college and have taken some courses which explains addiction, pain relief, aging, substance abuse and so on.
Can Narcan make a person addicted just as if it was a prescription or another drug.
Also, I checked out your mask fog prevention video an hour ago and found it helpful to learn about how to reduce foggy glasses.
I left behind a link to a product that may help because I purchase mine's last Monday and it has made a difference in wearing a mask to where I can breathe better and less suffocation.
I also have some other tips on how to reduce foggy glasses.
1 Use good anti-fog product.
2 Place glasses on top of the mask.
3 Fit mask to your face.
4 Use medical tape to create a seal.
5 Absorb the moisture by inserting tissue inside the mask.
Thanks Malik. Narcan does not create an addiction. Narcan has no effect on someone who has no opioids on board.
Thanks for the clarification Mrs Tammy, I really appreciate it.
Saved my life last night
Happy to hear 💕
great info, many thanks UK
Glad it was helpful!
I’ve always wanted to know what other things can narcan take care of
Opiods
Cool
Thank you
Can you do a vid on how to use the nasal spray please
I don’t have access to the nasal spray for demo. If I get a kit, then I will
@@NurseMinder Thanks
Would it be legal for me, a citizen of North Carolina, to carry Narcan in case of an emergency where I have to use it to save someone?
It is handed out here free no questions asked
Yes! Please carry Narcan! You could save someone's life! I've been carrying for years.
of course the first time you needed to use narcan was in downtown winnipeg😂
Familiar with the area are you 😁
my son needed 4 doses last night
Yes it is commonly needed more than one time. I hope all is ok
When someone is overdosing there no way in hell you got the time to take a wipe and clean the vile
I get it. It feels like a stressful situation and that every second counts, but you have time. Research shows we can go up to 4 minutes without oxygen before damage begins
Can you explain accutane
Did you find your answers? I have not researched accutane yet
Cool stuff
me at 2am
if any one need Opiod to forget pain. It's much better to smoke weed than opiod.
Narcan will bring the dead back to life
Not quite - but it feels like it
@@NurseMinder I've seen that stuff work like and off and on switch
Working on a song.
Woke up with shit in my nose
Smell was stuffy and i needed to blow
People hold me down tell me its okay
This is gonna be an interesting day
Ambulance rushes me away
Make small talk the nurse, name was Trey
Worked in biomedical
Told me my weed had fentanyl
Arive at the hopital, feelin blue
Wondering if my suspicions are true
That my dealer is
A massive fucking piece of shit
They wheel me to my new apartment
Nurse reaches in the glove conpartment
Touches my face and checks my eyes
Holy fuck I want fo die
Parents arive, blank look on their face
Tell me I'm the family disgrace
Sounds like you have had an experience
u bad i’m ngl
?