Charles Chalfant PhD, More people die from sepsis every year than two 747s crashing every day.

Charles Chalfant PhD, Professor, Division of Hematology & Oncology, Department of Medicine
Transcript:
What I love about my research is that it's ever-changing, is that it's always a
puzzle you get to solve, and at the same time, I get to possibly help people or have something translate to the clinic that can benefit a number of patients with certain diseases.
My name is Charles Chalfant and I'm a professor of Medicine and Cell Biology here at the University of Virginia School of Medicine. Here, I do basic biomedical research, examining how there are
different cellular mechanisms that are affected in disease states, and we try to take
advantage of those in order to possibly translate to the clinic.
Our current research is showing that there are particular proteins or enzymes in cells that are dysregulated in disease states, particularly in treating sepsis, this is a very difficult condition. More people die from sepsis every year than two 747s crashing every day. Also, this particular enzymes we look at that we're trying to develop these inhibitors and use ones that are already established and evolve those to where we can take them to the clinic, also will benefit certain patients with non-small cell lung cancer, as well as even enhance wound healing.