SAR of Aminoglycosides || Structure activity relationships

Amine group plays a key role in aminoglycosides which can have variable effects when it is attached to any of three rings. In this video, we will see how these amino and hydroxy groups influence the therapeutic activity as well as chance of inactivation by the bacterial enzymes.
#Aminoglycosides
#structuralactivityrelationship
#antibiotics

[@dennohtosh9502]

Thanks for the awesome video. Very elaborate🎉

[@egpat]

You are welcome !

[@lathzn9303]

pls check structure of kanamicyn A, in Foye's Principles of Medicinal Chemistry, on positions 2" is NH2 group, on position 6" is OH (partIII,1108 page).

[@satyasainaik3861]

Very interesting explanation

[@anju4687]

best explanation ever

[@lilimarowan5366]

رحم الله والديك♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️♥️

[@arvindkumarsharma6654]

Very helpful video🎥

[@mohanreddyvallur2145]

Really fabulous sir ,,
The way you explained just fantastic ❤️❤️

[@egpat]

Thanks a lot for liking video.

[@parthtakey9843]

Really helpful sir....please also upload nomenclature for aminoglycoside

[@priyankavats2241]

Too good.u made it really easy to remember.

[@egpat]

Glad it is helpful. Thanks for watching.

[@alphagonist4748]

Very useful

[@sammysammy5995]

Thanks for all the videos. Video on SAR of tetracycline please.

[@egpat]

Noted

[@salmadore550]

strong thanks🎀

[@anoopantony8718]

Best vedio for sar

[@egpat]

Thanks for liking.

[@nihaljagtap4873]

Very simply and nicely Explained

[@nihaljagtap4873]

Thanks a lot

[@normieev7662]

Hi! nice video, can you please tell me in what book can i find this information?

[@DrxKeshavKumar]

Med chem 3 book price on Amazon 250 rupees purple colour cover

[@mishalchaudary004]

Which part of the structure is responsible for nephrotoxicity???

[@DrxKeshavKumar]

Maybe aminocyclitol

[@rohitharohi5038]

Blessed for being your student sir... your videos and classes are really our saviours...thankyou for sharing us drops of ur ocean(knowledge)..🙏🙏

[@egpat]

Glad you liked the videos. Thank you and keep watching.

[@newtonowaga6433]

*6:21 All kanamycins have OH group at 3' position! I almost stopped proceeding beyond here when you said the exact opposite... I checked and concluded maybe you meant to say Gentamicin, or tobramycin! nice video though, but not the best!!!

[@egpat]

Thanks for notifying. I will edit it and check rest of video. Thank you.

[@ousmanedhnon8565]

كسا

[@shubhamsurya4267]

Kuch bhi faltu ka

[@sathishkumark868]

Very useful

[@egpat]

Glad to hear that