How Enzymes Work (from PDB-101)

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  • čas přidán 19. 04. 2017
  • Every second inside every living cell, thousands of chemical reactions are taking place. These reactions constitute the essential tasks of life such as metabolism, protein synthesis, cell renewal and growth. Learn how the proteins called enzymes work to maintain the rate of these reactions at a life-sustaining level.
    Based on atomic structures from the PDB archive, observe the mechanism of aconitase, an enzyme of the citric acid cycle, to understand how enzymes utilize their amino acid residues to catalyze a reaction.
    To learn more about enzymes, explore the educational resources on PDB-101 (pdb101.rcsb.org/browse/enzymes).
    Story by: David S. Goodsell and Maria Voigt
    Animation and Video Editing by: Maria Voigt
    Narration by: Brian Hudson
    Subtitles available in:
    English
    Catalan (translation by Marc Isbert)
    Spanish (translation by Marc Isbert)
    French (translation by Marie-Cécile Darmon)

Komentáře • 604

  • @RCSBProteinDataBank
    @RCSBProteinDataBank  Před 6 lety +58

    To contribute subtitles to this video in your language, use this community contribution link:

  • @ProfessorDaveExplains
    @ProfessorDaveExplains Před 5 lety +684

    This is really good.

  • @michaeladdis3323
    @michaeladdis3323 Před 4 lety +212

    I've always wanted to know the exact mechanism of how chemical bonds are rearranged in an enzyme's active site instead of just "enzymes speed up a chemical reaction". This helped me gain some insight on that. Thanks a lot!

  • @cancelled_user
    @cancelled_user Před 4 lety +85

    I can't believe we have really mapped every individual atom, it's position and movement within such huge molecules. At least that's how it appears to me in this kind of animation. It's absolutely amazing.

  • @rsrt6910
    @rsrt6910 Před 5 lety +115

    From what i understand, those reactions really do make those popping sounds.

  • @robertspath6928
    @robertspath6928 Před 5 lety +79

    Biology professors around the world thank you for this wonderful video!

  • @BonyMotoFilms
    @BonyMotoFilms Před 6 lety +43

    Finally got relief from my hunger of visualising this complex reactions. Thank you so much🙏🏻. More videos like this please

  • @HalimSakarya
    @HalimSakarya Před 7 lety +300

    Awesome animation. Please, please, please produce more like this.

  • @ultiumlabs4899
    @ultiumlabs4899 Před 4 lety +9

    this is THE BEST 3D animation I found about enzymes, super clear explanation, beyond my expectation. thank you thank thank you!!!

  • @michellebillen5500
    @michellebillen5500 Před 6 lety +10

    I can not believe how detailed and clear this video was! Thank you so much!

  • @blubberking100
    @blubberking100 Před rokem +1

    Came from "In a nutshell: You Are an Impossible Machine" and I feel like this video was a natural extension to their content and answered pretty much all the questions I had about that side of enzymes and portions

  • @sethfinck4301
    @sethfinck4301 Před 6 lety +5

    Thanks for the great video! Thanks for showing the mechanism of action in the active site; these types of details are almost impossible to find in video form. Great narration too. Thanks!

  • @bennymartin607
    @bennymartin607 Před 5 lety +7

    Great explanation on what enzymes are and how they assist in the chemical reaction process. Thanks a lot.

  • @MDZac2024
    @MDZac2024 Před 5 lety +5

    Superb video with amazing animation. Absolutely stunning that our DNA codes for such a vast array of protein structures. Thank you for sharing.

  • @theeraphatsunthornwit6266
    @theeraphatsunthornwit6266 Před 3 lety +76

    yesterday my citrate friend went to that enzyme hole, he came out a totally different person.

  • @nels6991
    @nels6991 Před 5 lety +3

    BRAVO! This is the best video I have seen of enzyme action, I will be sharing this with my students.

  • @ronkirk5099
    @ronkirk5099 Před 3 lety +4

    Even though I went on to become a mechanical engineer, I really enjoyed chemistry (only inorganic required) and have always wanted to learn more. This was a great animated video which really allows visualization of how enzymes work (Duh, I guess that was what you were going for).

  • @edgarramirezhuerta1864
    @edgarramirezhuerta1864 Před 3 lety +1

    This is the most beautiful part of my day so far!!

  • @vladghies3002
    @vladghies3002 Před 2 lety +1

    Animation quality is very good! Many textbook pages condensed in a 5 minute video - beautiful😀

  • @tomjerry84
    @tomjerry84 Před 5 lety +8

    I love watching these molecules react with each other. So cute, like little animals playing