Antinuclear Antibodies (ANA) test and their patterns | ANA test | What does ANA test positive mean?
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- čas přidán 7. 07. 2024
- This video talks about the science behind ana test. This video will answer the following questions like:
What does it mean if your ANA is positive?
What diseases cause a positive ANA?
Is a positive ANA test bad?
What is a normal ANA level?
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Thank you so much for this very informative video. It helps me understand what my positive ANA means and doesn't mean, bringing some peace of mind.
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Thank you for your informative video. My ANA came back as positive for homogeneous 1:320 and speckled 1:160. I'm having a hard time getting someone to listen, do further testing, and not just dismiss me. I have had joint pain for several months and have a weaker immune system and am an asthmatic. I'm very fatigued and this is all affecting my quality of life and I'm only 32. Sometimes it is hard to find a provider to take you seriously.
I am so sorry about your situation. I can imagine how bad does it feel. Please engage your self in some hobby such that you dont think about it much.
Go to quest and pay out of pocket for your test yourself
I understand ❤ I’m 25 and have felt like this for over 10 years. Just got positive ANA 1:640 homogenous and I work 2 jobs and help my disabled mother. It is the hardest trial ever! I got positive Ana last year and since then I have been seeing doctors and still have not found a thing lol. What a long journey it is! Don’t lose hope. Keep fighting! We got this
Exactly! My GP also dismissing me. What is it? Why the heck can’t they just follow up on things. Oh I know.. they get pissed off when you try to tell them what you need. It’s like it was 50 years ago. Their egos are so big and you can’t upset these demi gods and try to take your own health into your own hands. I’m going to keep trying to get someone to listen.
I have just received my positive ANA result and found this video on CZcams.
I am 32 and had no idea about it. My liver ALT values are high and the doctor asked me to do an ANA profile test. Don't know what next.
i’m 27 ANA positive 1:40 speckled with elevating platelets. I finally found a Doctor Who is taking this seriously and trying to get to the bottom of it. However, rheumatologist don’t want to see me. My PCP has given referrals and the rheumatologist just continue to give me the runaround saying that results are not substantial enough.
Thank you so very much for explaining this topic
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I've had Fibromyalgia for approximately 35 years I'm much better but now all of a sudden I've got Lupus my test results showed ANA 1.80 and Homogeneous, the problems I have are body pain even that has improved and fatigue now and then, I do have a bladder and colon problem. Please advise
Thank you so much, very informative 😊
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Could you please answer my question?
Can ANA test (IFA, 1/80, IgG) show a response of the body to a metal implant (titanium screws on the jaw)?
Is an autoimmune/autoinflammatory response can be induced by metal adjuvants and may they cause a positive ANA test result?
Or, could we say a negative ANA test means there is no response of the body to the metal (titanium) implants?
I have positive ANA with cytoplasmic pattern and can find very little information about it. I have Hashimotos and MCTD, plus undifferentiated hypophysitis (reduced pituitary function). Would like to know where best to look next and best treatment options.
My DFS70 antibody results is also very high it is 78.0 u/ml and my ana titre IIF is 640. Negative for schlorosis and RA. I do have rosacea on my face. Negative for lupus as well. My ana pattern is nuclear homogeneous . I dont know what this all means my doctor didnt either. I did find out i am also insulin resistant i did all these blood tests together
What if we have a 1:640 and it was nuclear and homogeneous? what is it, my doctors are taking to long for my appointment
Thank you
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Bestest video😊
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Ana 61.04 AU/ml value mean whether it's positive or negative
my ANA IFA came back positive but negative for ANA blood test. I have raynauds with symptoms of scleroderma. dusky, swollen fingers and toes with joint pain. rashes upper arms, thighs and buttocks. keep getting told i'm fine. any ideas?
This was explained so well even a layman could understand. Thank you very much.
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@@animatedbiologywitharpan Yes, I will also subscribe your channel and engage future videos. I can tell you put a lot of effort into making these.
Cronic gastritis main ana test kar sakta hain kay ana test karna sa autoimmune gastritis ka pata chal sakta hain
Thankyou for this video God bless you
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
@@animatedbiologywitharpan of course brother 🤍
Thanks sir
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My Ana test came back as a 13.1 value which shows negative,but i was referred to the rheumatologist because i tested postitive Ana at my primary care doctors office.
My ANA value is 27.10 plz help
You should check your ana with hep-2 cell and immunofloresan or hep 20-10 cell
Does a positive ana mean lupus
Who the hell are you supposed to believe one of my primary I should say PA who I saw on a regular basis when I was tested and told my blood work results for RA they told me after taking medication for the RA test for my blood came up with me having kidney problems she wanted to give me kidney medication. They want to put me on kidney medication, was she trying to make money for the pharmaceutical Companies?
I got rid of that particular primary care place. I don’t have kidney problems.
I know you can get certain side effects after taking prescriptions for autoimmune symptoms.
and also you need to listen to your body. You know you’ve already better than anyone else you know I don’t feel right or hurt or your pain and you have to figure out what’s the best things for it cause the doctors don’t always know. I don’t think all you have to keep finding a doctor that will be willing to go the length of trying to straighten out whatever autoimmune problem you have!
ANA test was positive and dense fined speckled was 1:80 what does that indicate
Was Sjogren's mentioned?
THANK YOU SO SO SO SO MUCH
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what is nucleoli fine granular pattern
Thank you 🙏🏽🤍
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
So if my test is 1:1280 speckled it is likely to be confirmatory right?
Can a positive anti scleroderma-70 antibodies be ANYTHING other then lupus or systemic scleroderma? I have zero symptoms of either
I’m in the same situation. It can take many years to develop. I thinks about 50 percent chance of developing scleroderma within the next ten years.
Hello, thank you for the video. Which test result would be Spindle fibers ?
ANA patterns, particularly those directed at the mitotic spindle apparatus (MSA), are not well understood and are rare.
@@animatedbiologywitharpan Thank you for your reply by the way!
Mostly it's unknown...I have no clue
My ANA test came back positive titer (1:320) with it saying speckled and homogeneous. I also have been having the rash on my face and my joints have been hurting
How is your health now?
What mean weak positive 1:100 ac8 homogenous nucleolar with fluctuate rnp weak positive antibody not another antibodies
My ANA ranges over 30 years from 600s to 5000 range. It's been dismissed as Lupus by some doctors because the anti-dsDnA is negative. Other doctors were concerned. Despite symptoms. I wonder what this can mean.
Me too
This test should br followed with other investigations (includs Laboratories & History and physical examination). If clinical picture is suggestive of a certain disease like lupus. -ve dsDNA is not necessary to diagnose. Although specific to lupus, +ve dsDNA is only seen in patients with internal organs affection, rather than superficial symptoms like joint pain ect..
if symptoms are present, usually treatment is initiated with following up on labs and symptoms.
You should always follow up with a one good doctor to have a clear idea about your concerns 👍🏽
From my experience, doctors who don't consider the history, are not good at assessment of autoimmune conditions.
I wish you happy healthy life
That’s interesting I was mostly reading your comments I have RA should I ask my doctor for RA to test me for this my blood work that I looked over had lupus but she she put me down as rheumatoid arthritis and my feet and hands I’m on Orencia which is helping somewhat and I have no idea what the long-term side effects will be
Good to hear that
What about a mitochondrial pattern in a positive ANA test? Can that be present in Lupus as well??
Recent research reveals the involvement of two distinct components of the mitochondrion: the mitochondrial outer membrane and mitochondrial DNA. Antibodies to these two mitochondrial constituents were increased in both human and murine systemic lupus erythematosus (SLE), compared to controls.
www.ncbi.nlm.nih.gov/pmc/articles/PMC6418244/
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How does a antibody against nucleus work because antibody can't penetrate the cell membrane and going to attack nucleus ?
before staring the test permeabilization solution is added which mildly dissociates the membrane ( do not destroys it completely). Due to this the antibody could penetrate
TQ for uploading this informative video.
Sir This is my ANA RESULT by IFA
Serum Immunofluorescence
Result weak positive
Pattern Spindle poles
Grade ++
Medical remarks. Cytoplasmic speckled (1:100)
Estimated titre 1:320
I have URTICARIA PROBLEM
WHATEVER MEDICINES I TAKE FOR URTICARIA, IT MAKES SEVERE URTICARIA. Please suggest some solution. TQ sir.
Hello I had a Positive ANA titer test done years ago with the speckled pattern, I've never had the butterfly rash but I have eczema since childhood is that considered a mixed connective tissue disease? is my positive ANA test for the speckled pattern because of my eczema? I rarely struggle with outbreaks but I sometimes get fatigue
Hello, my daughter has the same problem. She too has eczema, her joints hurt and she gets fatigued. 😞. She is only 19. I pray that she doesn’t have lupus.
Please tell me that how positive ANA affects pregnancy?
Please check with doctor it can affect the fetus
Thank you so much for such an informative educational video, my ANA is 1:80. Positive SSA. Speckled pattern but all other antibodies are negative, tested quite a few times within 2 years . I was diagnosed as SLE. I am very confused about my diagnosis by the nurse practitioner , what do you think about the diagnosis? Thank you in advance for sharing your ideas?
Mine just came back as 1:80 homogeneous this video was such a great explanation. Hopefully I can get some answers on why I'm losing so much hair.
What is SLE??
Rehmatologist doctor check ip
I don't understand these tests and other things my positive ANA details are here, and I don't know what to do or which particular doctor I should consult 😭😭😭
ANA positive
Pattern coarse speckled
Estimated endpoint Titre 1/2560
Anti smooth muscle antibodies Negative
Anti mitochondrial antibodies Negative.
Please guide me.
I am 40 years old.
My mouth is stretched can't eat anything which has even a small amount of chilies
what does weekly positive mean?
Mine too sometimes weak positive sometime negative
Can you tell me about PCNA positive means?
It means you might have an autoimmune disease. Proliferating cell nuclear antigen (PCNA) antibodies are a rare type of antinuclear antibodies (ANA), historically considered highly specific for systemic lupus erythematosus (SLE). Recent studies showed they can be present in other autoimmune diseases
Thanks
Thank you so much for your efforts 🍀🍀💕💕
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Is ANA treatable
Did anat est change from become +ve to - ve
Its not possible i guess
You might be in remission... The medication you could have been taking
Sir RO-52 Positive he kya kar na he please help me sir
I had Ro positive, could be Sjogrens disease or maybe lupus? They can overlap too
@@angelasardena599 any problem
My ana test report is 14.4 what does it menas??
How are you doing now?
X-rays of both my wrists shows arthritis. My rheumatologist ordered labs. My ANA test was POSITIVE, anti nuclear antibody ABNORMAL, and homogeneous ABNORMAL. No family history of RA. I have been wondering if my direct exposure to toxins (inhalation, skin, and ocular contact) have anything to do with what the labs show. To name a few: Benzene, xylene, hexavalent chromium, hexamethylene diisocyanate, butyl acetate, methyl ethyl keytone, etc.). The exposure occurred in 1982 when I was spray painting vehicles with a polyurethane paint. I did not use a respirator or any other form of PPE. Anyone?
It's less likely that it's due to those spray painting stuff. Autoimmune diseases doesn't devwlop like that
My ana Test report 17.9
The result of an ANA test is reported as a titer, which represents the level or concentration of antibodies detected in the blood. The titer is expressed as a ratio, such as 1:80, 1:160, 1:320, etc. The number before the colon (:) indicates the dilution of the patient's blood sample that still shows a positive reaction.
In your case, an ANA test result of 17.9 is not typically reported in the usual titer format. It's important to note that specific laboratories may have their own reporting methods, so it's best to consult with your healthcare provider
my mom's result came and it is 1:100...is there any chanch...that she had cancer?..its neuclear homogeneous type...
I don't think she has cancer. Moreover ANA test is not for detecting cancer. It's for detecting autoimmune disorders
Is there a way you can help me interpret my blood work?if so I can email my results.
I am a scientist and not a doctor and ethically i can't do that. Please consult a doctor
@@animatedbiologywitharpan I understand. What if a ds- DNA test came out negative along with a ANA test. 1:640. Is there more testing available
Is Seronegative a real thing
Yes seronegative means not much autoreactive antibody. At worst case I also possible the test did not work. Malar rash is pretty common signature
I wanted to ask if you questions regarding your other comment? I’m a 28 year old who has had the same problem. Where do I message you?
I have a positive ANA with positive dsDNA, but everything else was negative. Confused as to why.
Any further updates, my ANA came out to be positive today, I am really concerned ☹️
@@tejask4889 are you okay now?
@@syamaravi2410 Hi, I am doing ok now, doctor told me to ignore the ANA result for now, unless I get another attack of ‘uveitis’, I did a MRI and few blood tests, and I am lucky enough since all the results were as expected. Thank you for asking :)
@@tejask4889 why MRI?
@@syamaravi2410 Just to make sure I don’t have arthritis, since uveitis is a form of inflammation, the doctor wanted to make sure there is no such swelling in other parts of the body..
i recently had an ANA test done. My result came back as positive ANA titer (1:320 speckled). My covid test also came back positive. I did not know that I had covid while I was getting tested. Could covid be the reason as to why my results came back so high?
Its highly unlikely that two things are related
I have the exact same results except no covid
I have same doubt.have you consulted doctor regarding ana positive? Plzzz reply
I heard direct from a very serious dermatologist that are starting to see a relation between ANA positive, micro lupus reactions after getting infected by Covid-19’s
My ANA test was positive, titer is 1:80, dense speckled, joint pain. Need help with this.
Did you find out?
Does a positive ana test mean lupus
Yes but it has to be corrected with other clinical condition. AnA detects auto reactive antibodies
@@animatedbiologywitharpan so just because u test positive doesn't always mean u definitely hsve lupus
My ANA is positive 1:100 what is that
In this case, ana titer of 1:100 means that your blood sample was diluted 100 times and antinuclear antibodies were still detectable. It's important to note that an ANA test alone is not sufficient to diagnose a specific autoimmune condition. ANA positivity can be seen in various conditions, including systemic lupus erythematosus, Sjögren's syndrome, rheumatoid arthritis, and other autoimmune diseases, but it can also be found in healthy individuals or individuals with other non-autoimmune conditions
Hello there how can I contact you please???
Contact me for what ?
I couldn't understand you.
I am so sorry to hear that.
Is that a bird in your background audio? Wild or pet?
It's wild bird in the garden. I feed them and they often visit the house
Is it a wild parrot? @@animatedbiologywitharpan
Use AI voice next time. Can't understand Indian
Could you please help me by sharing my contents with your friends group/ college group. I put huge efforts in making these videos but unfortunately not a lot of people are watching this.
@@animatedbiologywitharpanI could understand your accent fine. Thank you for making this video in your own voice.
Thank you for this! 25 female Positive ANA 1:640 homogenous. Everything is coming back negative and unfortunately pain is getting worse prayers please 🤍
I have malar rash and severe muscle joint pain and trouble gaining weight and brain fog high blood pressure and high heart rate insomnia etc etc! MRI DNAds and all the lupus and connective tissues are negative.
I am so sorry to hear about your situation
I hope you are doing well, my prayers are with you😊