Synthesis of eicosanoids (prostaglandins, thromboxane, leukotrienes)

Sdílet
Vložit
  • čas přidán 9. 06. 2019
  • Donate here: www.aklectures.com/donate.php
    Facebook link: / aklectures
    Website link: www.aklectures.com

Komentáře • 183

  • @Hwo123
    @Hwo123 Před 5 lety +73

    FIRST! We miss you! Come back!!

    • @Biomeducated
      @Biomeducated Před 5 lety +5

      Indeed, finally a new video! I didn't put AK Lectures on #1 in my Top 10 Biomedical channels video for nothing. You're the best AK!

  • @jamessoto5723
    @jamessoto5723 Před 4 lety +6

    You helped me during undergrad and now you're helping me in medical school. Thank you GOAT.

  • @yarashhab
    @yarashhab Před 5 lety +28

    i literally have my biochem final in 6 hours and i was struggling with the arachidonic acid.... thank god i have his post notifications on

  • @damaster7276
    @damaster7276 Před 5 lety +27

    Literally the most in depth and best Channel in terms of explaining/understanding

    • @AKLECTURES
      @AKLECTURES  Před 5 lety +6

      Thank you! Glad you think so :)

  • @jonathanstartin3748
    @jonathanstartin3748 Před 5 lety +29

    Just saw this posted and I'm so STOKED YOU ARE BACK

  • @mmmmmmmmmmm111
    @mmmmmmmmmmm111 Před 4 lety +12

    Just a small correction on 1:15, linoleic acid is an omega 6 fatty acid but it's not a 6 carbon fatty acid, it's 18 carbons.

  • @anisfarhad1506
    @anisfarhad1506 Před 4 lety +9

    I cant believe you have a whole video on this exact topic! i was so lazy to learn it from my book with all the crazy steps, you simplified it brilliantly

  • @JoshuaKevinPerry
    @JoshuaKevinPerry Před 5 lety +11

    Welcome Home, we missed you.

  • @ramchandrasuthar2848
    @ramchandrasuthar2848 Před 5 lety +9

    GOOD MORNING SIR
    LIFE SCIENCE TIGER HAS BEEN ARRIVED AFTER SOOOOOO LONG TIME
    WELCOME SIR

  • @Lina-srkajol
    @Lina-srkajol Před rokem +2

    CANT THANK UUU ENOUGH, im a 1st year med student, and i couldnt understand what this is all about, u made it way clearer

  • @crunkbeast
    @crunkbeast Před 5 lety +5

    Thank you for your time and all you do. Your work is appreciated more than you can ever know

  • @lubnajan9108
    @lubnajan9108 Před 3 lety +1

    Didn’t know will be seeing your video posted two years before in my medical school. Loved it. You just explained it so beautifully ✌🏼

  • @797brm
    @797brm Před 5 lety +6

    Glad you’re back

  • @hazarbuyukakpnar1356
    @hazarbuyukakpnar1356 Před 5 lety +2

    Omg you're still active! We've missed you so much.

  • @jacquesdalias5939
    @jacquesdalias5939 Před rokem +2

    Thank you for this video. You wonderfully summarized the proStaglandin-leukotriene cascade in one page which makes it much more easier to understand. REALLY HELPFUL!!

  • @ekitochin6059
    @ekitochin6059 Před 5 lety +2

    Thank you and welcome back!You are my best teacher!
    欢迎回来,谢谢你做的一切!

  • @kabikabi9028
    @kabikabi9028 Před 5 lety +3

    We miss you, thank you for your time.

  • @MxLiKiE
    @MxLiKiE Před 5 lety +12

    He’s back! I dont need to learn this but now i want to

  • @nikkyuong6793
    @nikkyuong6793 Před 5 lety +2

    Ommmmmmgggggg... welcome back. You don’t know how much my class miss your lecture :)
    Okie study time now

  • @manarabdelaziz6302
    @manarabdelaziz6302 Před 5 lety +8

    He is back ❤❤

  • @mathilda_dada
    @mathilda_dada Před 10 měsíci

    Thank you.
    Your explanation is so comprehensive and wholesome

  • @dankgamer2004
    @dankgamer2004 Před 5 lety +1

    The legend is back

  • @nutzeeer
    @nutzeeer Před 5 lety +1

    Cool to see new uploads. I am just watching all of biochemistry. Cant wait to hear all the newly discovered things!

  • @77mayanksingh45
    @77mayanksingh45 Před 5 lety +2

    Welcome back sir!!!!!!!
    I can't believe it❕❕❕❕❕❕

  • @matthewshields7281
    @matthewshields7281 Před 5 lety +4

    Whoo welcome back!

  • @camilojoseacevedo8525
    @camilojoseacevedo8525 Před 5 lety +3

    Excellent as always!

  • @TheToxicMegacolon
    @TheToxicMegacolon Před 5 lety +21

    A random GOAT just popped up into my feed. Nice

  • @medical12262
    @medical12262 Před rokem

    U saved my life tnx
    I have watched every single videos but this one was the only one who really helped 😊👏🙏

  • @priyadharshaniyappan2196
    @priyadharshaniyappan2196 Před 5 lety +3

    Happy to see you back😀😀😍

  • @zavionw.8052
    @zavionw.8052 Před 5 lety +1

    Welcome back, AK!
    Great videos by the way :)

  • @miranmuslem
    @miranmuslem Před 10 měsíci

    Thank you for making me a good doctor! I appreciate you a lot...

  • @MahmoudMohy82
    @MahmoudMohy82 Před 5 lety

    Best lecturer, welcome back
    -Egypt

  • @musicmakkataei9705
    @musicmakkataei9705 Před 2 lety

    The best video I found on this topic

  • @salikmanan5681
    @salikmanan5681 Před 3 lety +3

    COX 1 produces pgf2alpha and TXA2
    COX 2 produces PGI2 and PGE2 .
    According to lippon

  • @kibanaru221
    @kibanaru221 Před 5 lety +4

    Well, not even done with gen chem 2 and I’m scared already but glad I have you 😭

    • @AKLECTURES
      @AKLECTURES  Před 5 lety +1

      Take it one step at a time, this stuff is great! You'll love it :)

  • @abedgamer7773
    @abedgamer7773 Před 2 lety

    This helped me A TON .... idk how to thank you

  • @Hematite-Heart
    @Hematite-Heart Před 5 lety

    He still exist! Thanks for my amazing biochem grade!

  • @mr-wc3xq
    @mr-wc3xq Před 4 lety

    Dr Andrey you're the best ❤

  • @princeetok1018
    @princeetok1018 Před rokem

    Great lecture. You make complicated topics appear simple

  • @sanchezjimenezisai4718
    @sanchezjimenezisai4718 Před 5 lety +13

    Yes!! You're back, greetings from Mexico 🇲🇽😁😁

  • @manarabdelaziz6302
    @manarabdelaziz6302 Před 5 lety +2

    We miss you 😍😍😍

  • @yourstrulychaos947
    @yourstrulychaos947 Před 4 lety +1

    I'm becoming good at biochemistry,Thanks to you🥺

  • @blueberry11051
    @blueberry11051 Před 3 lety

    Great guy. Wonderful explanation. Thank you very much.

  • @ravinaa315
    @ravinaa315 Před 5 lety +3

    You're back :)

  • @Medicose2282
    @Medicose2282 Před 4 lety

    May Allah bless you..doing extra Ordinary job👍🏻

  • @elaphmadallahsh7811
    @elaphmadallahsh7811 Před 3 lety

    Do you know You are amazing..thank you from Iraq..
    شكرا لك 🌹

  • @genuine_meteen9169
    @genuine_meteen9169 Před 4 lety

    Sir..I Really Like your Lectures.. Well Explained in Detail of what Is Just Needed...thank U So Much👍👍

  • @MarkIron
    @MarkIron Před 5 lety +2

    Great video 🌟 One question, isn’t EPA and dihomo gamma linolenic acid are used too? Not exclusively AA in these pathways?

  • @haileynathan1644
    @haileynathan1644 Před 5 lety +4

    Thank you!!

  • @ThomasAlexanderMD
    @ThomasAlexanderMD Před 11 měsíci

    Beautifully explained

  • @Canada2760
    @Canada2760 Před 5 lety +1

    Great Video.

  • @abdulazeez.98
    @abdulazeez.98 Před 5 lety +1

    You’re back :)

  • @mrsboogybren2657
    @mrsboogybren2657 Před 3 lety

    Thank you for the explanation. I really appreciate it. 😊

  • @takashikun5446
    @takashikun5446 Před 5 lety

    After a long time
    Have great journey ahead

  • @urvimehta9717
    @urvimehta9717 Před 2 lety +2

    Hello, thank you for an informative video, loved it.
    I had a question. In 4:15 you mentioned that PGI2 inhibits platelet activation and formation. Should it not be the opposite? As NSAIDs like Aspirin reduce platelet function.

  • @nadahussam5849
    @nadahussam5849 Před 2 lety

    Just subscribed. You're great!! 💜

  • @user-jd8qz5nw8x
    @user-jd8qz5nw8x Před 5 lety +1

    So good videos, thank you! Could you make a 5-Lipoxygenase specific one?

  • @vikas_kumar_sahu1965
    @vikas_kumar_sahu1965 Před 5 lety

    Missed you so much...it's so good to see u😍😍

  • @zaroonhaider9813
    @zaroonhaider9813 Před 3 lety

    Sirrrrr youu are just amazing🥰🥰you deserve even more subscribers🤩🤩🤩

  • @patiencechepkorir5596
    @patiencechepkorir5596 Před 2 lety

    Your lectures are awesome

  • @abdulbakiidriss806
    @abdulbakiidriss806 Před 5 lety

    Welcome back doctor

  • @amrelnhal9943
    @amrelnhal9943 Před 2 lety

    So freaking awesome!!

  • @poojak9421
    @poojak9421 Před 4 lety

    Wow this is the best explanation that I ever heard.. gonna subscribe your channel

  • @Larsa836
    @Larsa836 Před 3 lety +1

    Thanks for your efforts but I had noticed that you didn’t mention the prostacyclin in cox2 ?

  • @amermalik5885
    @amermalik5885 Před 4 lety

    he explained it very well

  • @329santoshsapkota3
    @329santoshsapkota3 Před 4 lety

    just love..
    thank u n thank u sooo much..plz upload more n more..

  • @mallakaljarawen888
    @mallakaljarawen888 Před 4 lety

    SUPER!

  • @pixiepower8052
    @pixiepower8052 Před 9 měsíci

    Also great lecture as a lay person I have a better understanding of what this is now 😊

  • @alikufi7948
    @alikufi7948 Před 3 měsíci

    amazing lecture

  • @kohinurkazal6788
    @kohinurkazal6788 Před 4 lety +3

    Doesn’t TXA2 belong to COX1? Kinda confused

  • @amnaalasha1552
    @amnaalasha1552 Před 5 lety +1

    Very interesting exploitation 👍

  • @lihanou
    @lihanou Před 5 lety

    wow he's back

  • @habibullah7117
    @habibullah7117 Před 5 lety +2

    Thank you sir for coming back ❤️❤️❤️👍👍

  • @sadeddeaded1091
    @sadeddeaded1091 Před 5 lety +1

    Welcome back

  • @richapandey3368
    @richapandey3368 Před 2 lety

    Thanks a lot

  • @hajerhaider6655
    @hajerhaider6655 Před 5 lety +1

    Welcome back
    I Miss your lectures
    Greeting from china 🇨🇳

  • @kradardsaii2351
    @kradardsaii2351 Před 9 měsíci

    Thank u so much

  • @MoonLight-sw6pc
    @MoonLight-sw6pc Před 5 lety +1

    Welcome back its really nice to see you again , how have u been?

    • @AKLECTURES
      @AKLECTURES  Před 5 lety +1

      Thanks! I've been great but a little busy :) hope all is well on your end too!

  • @chamikaishara3778
    @chamikaishara3778 Před 4 lety

    Thank you ❤

  • @ozfandukgaming6703
    @ozfandukgaming6703 Před 3 měsíci

    The link of your videos is placed in official portal of the medical university. I got acquainted with your channel using these links .😊

  • @funtolearn459
    @funtolearn459 Před 3 lety +1

    Sir please made more videos on heart related conditions. I am fan of your videos.

  • @yesminekallel2603
    @yesminekallel2603 Před 4 lety

    Thank you soo much. You are awesome ❤️

  • @EarlAndGrey
    @EarlAndGrey Před 3 lety +2

    Just to note; Linoleic acid is an 18C fatty acid with 2 double bonds, not a 6C FA as said at 1:16

    • @slavavassiliev3531
      @slavavassiliev3531 Před rokem +1

      I was about typing just exact the same thing but then had the great idea of scrolling through the comments firs ;-)

  • @aditimukherjee6789
    @aditimukherjee6789 Před 2 lety

    u make learning interesting

  • @zaheralsakka
    @zaheralsakka Před 5 lety

    Welcome back

  • @faisal2752
    @faisal2752 Před 5 lety

    welcome back

  • @kimhuyenhuynh1987
    @kimhuyenhuynh1987 Před 3 lety

    thanks so much! It's so awesome

  • @ramchandrasuthar2848
    @ramchandrasuthar2848 Před 5 lety

    Great analysis of BIOCHEMISTRY

  • @mudassarnadeem1778
    @mudassarnadeem1778 Před 4 lety +4

    Ah ..isnt it like this ...
    Thromboxane A2 is made from COX 1 and PGI2 and PGE2 is made from COX 2 ..thats written in Lippincot ...and in the video its opposite...
    its confusing me ...do correct me if im wrong.

  • @Biomeducated
    @Biomeducated Před 5 lety +1

    What a coincidence! I recently helped correct the Pharmacology exams of 3rd year Pharmact students with my Professor. One of the questions was: "Why are prostaglandinE2 analogs often prescribed concomitantly with NSAIDS if patients are to use them rather long-term?" The answer is in the video of course ;)

    • @AKLECTURES
      @AKLECTURES  Před 5 lety +2

      Thats great! Hopefully not too many mistakes were made. Good job on your channel btw, keep it up! Its great to see graduates who are passionate in their field becoming active on CZcams! :)

    • @Biomeducated
      @Biomeducated Před 5 lety

      @@AKLECTURES Wow, this means so much coming from you! Thanks a thousand! And if I could have only 50% of your passion I would already go further. You made almost 2000 videos, dude, you're an icon! (and a lifesaver for many!). You should become a professor!

  • @bismaikram6390
    @bismaikram6390 Před 3 lety +2

    Sir i want to know , isnt it opposite Cox 1 produces txa2 while cox2 produces pgI2?

  • @taeyang
    @taeyang Před 5 lety +6

    Just dropping by to drop a comment/thumbs up/contribute a view.

  • @afsarali3052
    @afsarali3052 Před 4 lety

    hero for me...

  • @marium1583
    @marium1583 Před rokem

    Your videos help me understand and grasp concepts , can't thank you enough
    🙌🏻

  • @arkveth6921
    @arkveth6921 Před 3 lety +1

    A small correction, linoleic acid is actually 18 carbon fatty acid, I guess Andrew wanted to say that it is Omega-6

  • @shizakhan240
    @shizakhan240 Před 3 lety

    Thnk u for help sir

  • @atahanersoy5168
    @atahanersoy5168 Před 3 lety

    hypertrophy canavarı olmuşsun andre

  • @pitcherine5842
    @pitcherine5842 Před 2 lety

    wawoooo ....thank you

  • @rickshawley7683
    @rickshawley7683 Před 4 měsíci

    So what is the best and safest way to block excess prostaglandin d2 production.

  • @lynnemaverick1865
    @lynnemaverick1865 Před 7 měsíci

    Boss, linoleic acid is an 18 carbon unsaturated fatty acid. You said 6. Please 🙏
    I'm learning a lot from this channel.