Mycobacterium Tuberculosis (TB) Immunology [Immunology basics, granuloma formation, TB reactivation]
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- čas přidán 15. 07. 2024
- Description:
Mycobacterium Tuberculosis is one of the most successful pathogens infecting over 1.7 billion people but only a fraction of these develop TB. The reason for this is your Immune system. In this video, we go through immunology basics, the immune response against TB, granuloma formation and consequences of reactivation.
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📝My Notes: drive.google.com/file/d/1hi_i...
🚩Timestamps
00:00 - Introduction
01:05 - Immunology basics
04:08 - Macrophages and immune evasion
05:21 - Dendritic cells to the lymph node
06:04 - T-cells to the rescue
07:21 - Granuloma formation
08:15 - Me having fun
08:53 - Secondary tuberculosis (Reactivation)
09:41 - Conclusion
🌟 Neuromuscular Physiology: • Neuromuscular Physiolo...
The caffeinated medic:
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Thank You.
This is the caffeinated Medic signing off, until next time, take care.
#PCScollaboration #TBimmunology
Love the humor sprinkled throughout!
great video man hope u continue to make more! good luck with your medical career as well :)
Congratulations for the video, really impressive!!
Great explanation!
Thank you! I couldn't find a nice in-between information anywhere which didn't either skip past most immunological steps or go into waaaaaay too much detail (which freaked me out).
One of the most accurate, and easiest videos for Tuberculosis immunity I've seen so far.
thank you so much for this!!!
Thank you very much
This is one of the easiest video to digest regarding immunology of tb. it would be great if you give the references also. thank you so much!
Thanks alot , it was so helpful, cleared all the concepts , also the illustrations are cute
This video is very helpful i hope you continue
Thank you very much bro you make my presentation so beautiful in my class
Keep doing lectures your very good
Thanks ☺️☺️
Thank you
Great video
That's a great lecture! Very well explained. Thank you !
Thank you ✨
perfect
Niceee🔥
Suggestion: use a better mic since I can barely hear!
Keep going I like your videos
Great video thank you. I think DAPMs stand for damage‐associated molecular pattern molecules.
Too 👍
GOAT
i love you man
Much much appreciated ❤️❤️
❤
best video ever explaining TB
So to be honest most of the information in the video comes from immunology and pathology textbooks….. i don’t really have actually textbook recommendations but I would recommend using the textbook that is recommended for whatever you’re studying and supplementing it with other resources (articles, videos, lecture slides, notes, etc).… it’s sucks but generally you can’t find all the information in one textbook… for example, I know people that remove the spine from a textbook, punch hole all the pages and bind them using a ring binder so that they can add information from other sources….. hope this was helpful … wish you all the best …
@@thecaffeinatedmedic7762 thank you for all that effort , plus thats true that is what im suffering from i cant find all the information together except in your videos all the love thank you :)
Is there a link between tb and granuloma anulare? If so....what is the cure?
Can you please share the references you used for this content??
Why does cavitation occur?
Do B cells play any role with immunity against TB?
That's a really good question..... B cells don't play much of a role because MTB is predominantly an intracellular organism and hence you mount a cellular response rather than a humoral response...... However, b cell do play some role... MTB does have an extracellur part in its life cycle so antibodies would be useful... Secondly b cells help modify the t cell response because they do interact with t helper cell...
Sorry... I know this is a messy answer... Hope it helps tho... Let me know if you have any more questions
@@thecaffeinatedmedic7762 Actually I'm doing a project on immune resposne against MTB and thanks to you I got to understand the processes. But if you could give me a clearer idea of what role do B cells and CD8+ T cells play, it would be much appreciated. I found out that in cytotoxic T cells there's an insufficient up regulation of perforin and granulysin expression but I'm not sure if they play some major role
Yes they do. More than just Ab production. Maybe have a read through these papers from my lab:
pubmed.ncbi.nlm.nih.gov/26611659/
pubmed.ncbi.nlm.nih.gov/31054408/
good summary @The Caffeinated Medic
This could be a great video, but you're talking way too fast. Also, some of the writing is small and so hard to read. :(
Thank you for your comment. I'll work on talking a bit slower and making the writhing a bit easier to read.... Also you could download the pdf in the description (might be easier to read the small writing)...
@@thecaffeinatedmedic7762 Sorry to be negative. It is a great video, I just couldn't keep up! I am a visual learner and really rely on videos to help me. I assumed your speed talking meant passion about the subject! Thanks for your reply! 😊
Thank you very much
Thank you very much
Thank you very much