Immune Response, Toll Like Receptors (TLR) Pathway - IMGENEX

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  • čas přidán 1. 05. 2011
  • Watch The second Video in the TLR Series!!!! - Don't for get to Like and Follow!
    • Innate Immunity: Viral...
    www.imgenex.com
    Toll Like Receptors: The GateKeepers of Innate Immunity
    Innate immunity as the first line of defense
    The innate immune system is an ancient host defense mechanism found in almost every multicellular organism from plants to humans. In invertebrates it is the sole mechanism of defense against pathogens but in higher vertebrates constitutes the first line of defense. The role of the innate immune system is not an insignificant one; not only must it discriminate between self and non-self as well as distinguish between pathogenic and non-pathogenic microbes, it also plays an important role in triggering and optimizing the adaptive immune response. This remarkable system allows an immediate non-specific response against microorganisms whereas the adaptive immunity mounts a specific response against the invading pathogen during the late phase of the infection.
  • Věda a technologie

Komentáře • 398

  • @killpy12
    @killpy12 Před 4 lety +69

    Absolutely horrifying and inscrutable. I love it, thank you

  • @litojonny
    @litojonny Před 9 lety +319

    this is what id imagine what studying immunology high must be like

  • @Airhockeylirare
    @Airhockeylirare Před 10 lety +404

    So this is what happens when microbiologists take LSD...

    • @joeshellhammer
      @joeshellhammer Před 9 lety +11

      I thought the very same thing when I first watched it, even though I really liked it. But, wow, what an imagination! Pretty impressive. I thought it would have been appropriate to have this video set to "Lucy in the Sky with Diamonds".

    • @prasadbotheju5682
      @prasadbotheju5682 Před 6 lety +1

      I'm researching relieving sarcoidosis condition naturally and found a great website at Remission Crusher Tactic (google it if you are interested)

    • @molecularunity
      @molecularunity Před 5 lety

      hahahahahahahahah

    • @rittenbrake1613
      @rittenbrake1613 Před 5 lety

      Nina Borodinskaja 😂😂😂😂😂😂👍🏻

    • @giannis101
      @giannis101 Před 4 lety

      Hahaha

  • @Guihlopez
    @Guihlopez Před 10 lety +58

    This video is absolutely amazing. Immunology completely makes sense after watching it. Congratulations to whoever made it.

    • @matthewcurry3565
      @matthewcurry3565 Před 2 lety +4

      I think someone poisoned me with literal LSD. What is happening?

  • @101Phase
    @101Phase Před 11 lety +16

    Believe it or not, I'm currently writing an essay on Toll-like receptor signalling for a coursework and this was the most accessible summary I've found so far. Excellent work!

  • @yeshitellaaleme4419
    @yeshitellaaleme4419 Před 3 lety +6

    I watched this 6 years ago and I wanted to watch it again then my mom put out a CZcams video and it popped up I'm crying tears of joy!!

  • @rickyroko1
    @rickyroko1 Před 8 lety +88

    This is the greatest ANIMATION i've ever seen in immunology! lots of love

    • @qingzheng7485
      @qingzheng7485 Před 4 lety

      me too

    • @kingsleyuduehikingsleyudue1494
      @kingsleyuduehikingsleyudue1494 Před 3 lety

      I want to thank Dr ehime herbs for the help he has rendered to me by getting Rid
      of my (HIV). I was Diagnosed in July 2018 but after the Usage of Dr ehime herbs
      Herbal Medicine, I was cured from (HIV) and the virus was completely gone
      from my body. The Symptoms of the (HIV) Virus is completely Gone.. So
      anyone who is having the virus should contact Dr ehime herbs to give you the
      herbal medicine to cure yourself. HERPES, You can contact on Instagram @dr_ehime_cure2 or contact WhatsApp number (+2348144387765) or email (drehimecure325@gmail.com)
      He cures all this illness,.
      1 cancer cure
      2 diabetes cure
      3 ringing ear
      4 herpes cure
      5 warts cure
      6 HPV cure
      7 Hiv
      8 get your ex back
      9 pregnancy herbal medicine
      10 prostate enlargement
      11 Hepatitis B
      12 Dysfunction...

  • @leticiacuellar6474
    @leticiacuellar6474 Před 7 lety +11

    Kudos to the producers for making this TLR series funky fun!

  • @juliaskripka-serry2537
    @juliaskripka-serry2537 Před 9 lety +90

    Welllll peeing my pants laughing is definitely not the outcome I was expecting when I youtubed TLR videos today

  • @russelmiller7311
    @russelmiller7311 Před 7 lety

    vivid explanation on the topic. Toll-like receptors (TLRs) are single transmembrane cell-surface receptors, which have a key role in the innate immune system. TLRs generally exist as homodimers (heterodimers have been reported) and are found on immune cells; macrophages, B lymphocytes and mast cells.

  • @HassanKhan-sx1nt
    @HassanKhan-sx1nt Před rokem

    content like this derived people's on youtube to clear concept such videos make study very easy so there is no excuse for no learning

  • @dr.salmanriaz1468
    @dr.salmanriaz1468 Před 8 lety +26

    what can u expect more than this?...
    lovely...thousands of heart loving kisses to the one who created

    • @rashaessam9426
      @rashaessam9426 Před 5 lety +1

      Dr.Butterscotch certainly great effort

    • @kingsleyuduehikingsleyudue1494
      @kingsleyuduehikingsleyudue1494 Před 3 lety

      I want to thank Dr ehime herbs for the help he has rendered to me by getting Rid
      of my (HIV). I was Diagnosed in July 2018 but after the Usage of Dr ehime herbs
      Herbal Medicine, I was cured from (HIV) and the virus was completely gone
      from my body. The Symptoms of the (HIV) Virus is completely Gone.. So
      anyone who is having the virus should contact Dr ehime herbs to give you the
      herbal medicine to cure yourself. HERPES, You can contact on Instagram @dr_ehime_cure2 or contact WhatsApp number (+2348144387765) or email (drehimecure325@gmail.com)
      He cures all this illness,.
      1 cancer cure
      2 diabetes cure
      3 ringing ear
      4 herpes cure
      5 warts cure
      6 HPV cure
      7 Hiv
      8 get your ex back
      9 pregnancy herbal medicine
      10 prostate enlargement
      11 Hepatitis B
      12 Dysfunction...

  • @DrP3natrator
    @DrP3natrator Před 7 lety +1

    Great video! I am a visual learner so it really helped me to put faces with all these things.

  • @jaquelinemanuel5716
    @jaquelinemanuel5716 Před 10 lety +1

    cute, entertaining, and interesting! I hope more videos on immunology and other topics in med will come soon! Thanks!

  • @edwardhaughney9665
    @edwardhaughney9665 Před 3 lety

    Rather stunning presentation. Pictures are more powerful than words. Keep up the good work. Don't usually care for music accompaniment but this seems to work.

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +1

    @bundawartini We tried to show as much information as we could. There are still many areas in which this video does not cover. We are releasing a 2-3 part series following up on these areas.

  • @Hellos.5
    @Hellos.5 Před 5 měsíci

    I can only imagine a game designer and a doctor collaborating on this 😂. It’s a wild ride.

  • @_SankalpaBhusal
    @_SankalpaBhusal Před 5 lety

    It was like a complete review for me!!! Great job...🙌✌🙌

  • @marvahkhalid5060
    @marvahkhalid5060 Před 3 lety

    wow this is soo amazing!! thankyou for your efforts in creating this

  • @bangtanbeau2131
    @bangtanbeau2131 Před 7 lety

    VERY GOOD ANIMATION. Thankyou! It helped me a lot!

  • @brazilian777able
    @brazilian777able Před 11 lety

    This is a very creative ingenious video. Excellent!!! I love the end with the showing of the cast. LOL

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +3

    @Mjhond Thanks, I appreciate it! We are working on more videos as we speak.

  • @anujapatil2902
    @anujapatil2902 Před 7 lety

    very thoughtful, thanks, guys for uploading this video!

  • @username7445
    @username7445 Před 3 lety

    The cast is very well chosen! Congratulations😂

  • @sophiabang7868
    @sophiabang7868 Před 3 lety

    When you leave no room in your budget for sound lol. Honestly though great video for visualizing TLR system and MHC II antigen presentation. Makes things make more sense as you read.

  • @tropicantei5550
    @tropicantei5550 Před 5 lety

    WAAAAW THANK YOU. YOU JUST SAVED MY FINALS x))))

  • @savi263
    @savi263 Před 4 lety

    Superb animation to understand the TLR biology! Thanks

  • @ita14
    @ita14 Před 12 lety +1

    B7 molecules are B7.1 (CD80) and B7.2 (CD86). They both bind CD28 to sustain T cell activation.

  • @esra11102010
    @esra11102010 Před 11 lety

    This is amazing. Keep up with the good work, I like them all

  • @uzmakhan9264
    @uzmakhan9264 Před 6 lety

    Truly it made my topic easy to remember !!THANKS😊

  • @bharathraj5862
    @bharathraj5862 Před 5 lety

    Great work!!
    Easy to understand and thank you.

  • @dezafeatle
    @dezafeatle Před 12 lety +2

    Very helpful video. Helped me understand my immuno-biology class a lot better.

  • @aishabhat2358
    @aishabhat2358 Před 6 lety +4

    This is toooo cute,never seen anything so interesting and creative related to my studies.
    Thank you so much for this animation❤

  • @caslandry2847
    @caslandry2847 Před 4 lety +8

    This is kinds how it feels when I study for my immunology final after a few too many edibles, and maybe some acid.

    • @kingsleyuduehikingsleyudue1494
      @kingsleyuduehikingsleyudue1494 Před 3 lety

      I want to thank Dr ehime herbs for the help he has rendered to me by getting Rid
      of my (HIV). I was Diagnosed in July 2018 but after the Usage of Dr ehime herbs
      Herbal Medicine, I was cured from (HIV) and the virus was completely gone
      from my body. The Symptoms of the (HIV) Virus is completely Gone.. So
      anyone who is having the virus should contact Dr ehime herbs to give you the
      herbal medicine to cure yourself. HERPES, You can contact on Instagram @dr_ehime_cure2 or contact WhatsApp number (+2348144387765) or email (drehimecure325@gmail.com)
      He cures all this illness,.
      1 cancer cure
      2 diabetes cure
      3 ringing ear
      4 herpes cure
      5 warts cure
      6 HPV cure
      7 Hiv
      8 get your ex back
      9 pregnancy herbal medicine
      10 prostate enlargement
      11 Hepatitis B
      12 Dysfunction...

  • @robbycanton8803
    @robbycanton8803 Před 7 dny

    that was so awesome, welldone.

  • @rrintan9140
    @rrintan9140 Před 5 lety

    W000WWW omg. thank you so much for creating this creative animation! this will definitely help me so much to pass the exam :)

  • @stemked
    @stemked Před 11 lety +1

    Very nice. I'm going to use this video in my Immunology class.

  • @vionagunawan5938
    @vionagunawan5938 Před rokem

    Wow this is so cool, and I can understand it immediately

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +2

    @jennyEvansmd Thanks for the comments, we are working on 2 additional videos that expand on this presentation. The new videos should fill in some of the gaps ins the sequence that is currently shown.

    • @giannis101
      @giannis101 Před 4 lety

      Go on ! You are the best ( greetings from Greece )

  •  Před 11 lety

    interesting animations you got there.
    Keep up the good work!

  • @Prettyspeck
    @Prettyspeck Před 10 lety +2

    Wish everything could be explained in this way. zthis is Amazing

  • @ashithak6268
    @ashithak6268 Před 3 lety

    Excellent. The video says it all....

  • @neerajpatil3735
    @neerajpatil3735 Před 10 lety +2

    Hey! You have uploaded a really nice video. But changes should be made in the names of all component cells and proteins. One can not see properly the names in lower resolutions.

  • @kakhangchungpanmei8205
    @kakhangchungpanmei8205 Před 11 lety

    So helpful. wasnt sure about PPR an TLR, now i know , ur website is really helpfull. kip up the good work.

  • @nav5679
    @nav5679 Před 10 lety

    incredible video! one of the best ways to learn this stuff :)

  • @priyankagorai6549
    @priyankagorai6549 Před rokem

    This is absolutely amazing

  • @nechamarakow3922
    @nechamarakow3922 Před 9 lety

    the best way to study! its really a difficult war going inside our bodies.

  • @Peter7beardmaster
    @Peter7beardmaster Před 11 lety

    this is exactly how Kuby's describes the process..you just won a like and subscription, thanks a lot

  • @drshwetalokwani3690
    @drshwetalokwani3690 Před 2 lety

    Thank you for making it easier

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +1

    @PastelitaVelys Do you mean our TLR book? Or another resource? Thanks!

  • @zeeto_k
    @zeeto_k Před 4 lety

    this video is more helpful more than my prof.

  • @Toughtriples
    @Toughtriples Před 7 lety

    its amazing keep uploading such type of videos

  • @marleneiradukunda4618
    @marleneiradukunda4618 Před 10 lety

    Great video!
    It's so easy to understand :)

  • @aleenajamil7495
    @aleenajamil7495 Před 10 lety

    Really good explanation and animations!

  • @Racheal700
    @Racheal700 Před 6 lety

    This is awesomeeee....things like this make it so much easier

  • @RaviSingh-yz9tx
    @RaviSingh-yz9tx Před 6 lety

    Awesome video with excellent presentation

  • @habibehk
    @habibehk Před 6 měsíci

    Saved it, and sent the link to my kids- Cool, fun and creative animation! If you can, please share the link(s) to your other work(s) in the reply to comment section.

  • @user-kx6gr6ky4b
    @user-kx6gr6ky4b Před 7 lety

    this is awesome and imaginative! well presented 😉

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +1

    @willamricard Thanks alot! More videos are on the way

  • @jessicakorupolu8190
    @jessicakorupolu8190 Před 8 lety

    thanks for the great video! It helped alot and really adorable.

  • @Mai0211
    @Mai0211 Před 11 lety +3

    love the animation! makes it much more fun to watch, especially for someone with a short attention span like me who's trying to study. But you should have someone explaining each process instead of music, that would be much better :D someone with a good cartoon voice.

  • @kimiaporkohan574
    @kimiaporkohan574 Před 2 lety

    Woww...this is amazing...thank you so much❤

  • @karleffertz
    @karleffertz Před 12 lety

    Great video!! when are 2 and 3 coming out??

  • @ekimzaga
    @ekimzaga Před 12 lety

    hell yeah, a video that is speaking in my terms!! house music, animation, and not dumbed down! =)

  • @EdwardCullenBby
    @EdwardCullenBby Před 12 lety

    Love this video!! Just what I needed to help me study :)

  • @Chryseis777
    @Chryseis777 Před 12 lety

    Excellent and superb!!!!!!!!!!!!!!!!!!!!!Bravoooooooooooooooooooooooooo!!!!!

  • @mindimpulse47
    @mindimpulse47 Před 9 lety +75

    it would have been bestt if there was commentary too .. for explaining the video

    • @sardarali2025
      @sardarali2025 Před 6 lety +1

      exactly

    • @nancyab9862
      @nancyab9862 Před 6 lety

      Exactly👌🏻👌🏻👌🏻

    • @jeherulislam6903
      @jeherulislam6903 Před 4 lety +4

      This video seems to be targeted to one who already knows the whole process but feels jumbled and would like animated description. Last time I watched i didn't get a things but now I can see why i didn't.
      So proper description is better to target larger audience

    • @rakshith1994
      @rakshith1994 Před 3 lety

      Read in textbook and come back and watch. This is a good video to a clear picture. PS: I read Veterinary Immunology by Ian Tizard 10th Ed before watching this. And it gave a super good clarity. You can choose your own books too.

  • @walidsong2255
    @walidsong2255 Před 4 lety

    Please explain the work of the enzyme 5 alpha reductase in changing the male hormone, and where it is produced. Thank you.

  • @MadrassaDzOubahMed
    @MadrassaDzOubahMed Před 5 lety

    Hi ...thank you very much for your videos ..
    could you tell me please the name of the program that can make that animation style ... thanks again

  • @rtpcr3969
    @rtpcr3969 Před 6 lety +21

    imagine being a molecule

  • @kandrew5v5
    @kandrew5v5  Před 13 lety +2

    @gutrp Thats Great! If I only I had videos like this through school, it would have made immunology a lot easier to digest!

  • @kandrew5v5
    @kandrew5v5  Před 13 lety +2

    Also check out Imgenex's new apoptosis detection tool called pSIVA

  • @areanaangel8964
    @areanaangel8964 Před 6 lety +26

    the music was nice tho. i was dancing in my room. lol

  • @02luvtrack
    @02luvtrack Před 9 lety

    This is amazing. Thank you so much

  • @ashwinishinde64875
    @ashwinishinde64875 Před 3 lety

    Please upload more videos ..... This is so easier to understand everyone ..... I have never see like this animation 😂🤦😍😍

  • @Saul_GC
    @Saul_GC Před 12 lety

    there are soooo many things other than what appears here that i must learn, may god have mercy on my soul, and on your souls if you are/will be in this situation

  • @katherinehume5058
    @katherinehume5058 Před 10 lety

    Excellent work!

  • @saumyaranjansatrusal764

    an amazingly interesting video i have ever seen..hats off to the creator, epic imagination...

  • @kandrew5v5
    @kandrew5v5  Před 12 lety +1

    @Ondelendo Our next video dives in deeper to the mechanism of host defense

  • @hgsnk333
    @hgsnk333 Před 11 lety

    Please (and thank you) make one for CLRs, RLRs and NLRs!!!

  • @fitriamelia6394
    @fitriamelia6394 Před 7 lety

    I like this video. It is funny and easy to understand

  • @raspberry996
    @raspberry996 Před 11 lety +2

    When I first read the title I thought it said 'Troll Like Receptors'

  • @capriccioso35
    @capriccioso35 Před 12 lety

    @gerbilinatube CD 80 is another name for B7 and yes it links with CD28 as a costimulator for T cell ( in this case, CD4 , helper T cells) activation

  • @kanzu4225
    @kanzu4225 Před 3 lety

    El vídeo es interesante para saber de las células y bacterias de como entran y las células se defienden mostrando como y que se usa para la defensa de las bacterias

  • @sxyngel
    @sxyngel Před 11 lety

    whats an ikb???? would help alot if you list the full names of all the abbreviations

  • @azeemnaeem6720
    @azeemnaeem6720 Před 4 lety +1

    Lovely inspiration for immunology

  • @fenotipobombay
    @fenotipobombay Před 12 lety

    what is the function of cd80/cd86? and why the microbe is destroyed once he gets (endocytosis?) inside the cell? what is the mechanism that lead to the production of the antigens linked to mhc II?

  • @dianachin8001
    @dianachin8001 Před 10 lety

    This is so cute ! Thanks for doing such a helpful video

  • @julianajesusdonascimento875

    Thank you soo much for class

  • @mozarliszt
    @mozarliszt Před 12 lety

    Very good video, so comprehensive!I love it.

  • @shraddhabhardwaj7596
    @shraddhabhardwaj7596 Před 9 lety

    Its simply awesome!

  • @investigacaopsicologiaavan8256

    Hi IMGENEX, can I download your video for my self? Thank you

  • @leonstellander8602
    @leonstellander8602 Před 3 lety

    I will never forget this

  • @khimbahadurale7079
    @khimbahadurale7079 Před 8 lety

    Really an interesting way of learning!!

  • @11nicolalbamamanimerlo18

    Bonito video que compartes, estubo muy interesante muy bonito gracias. En invertebrados es el único mecanismo de defensa contra patógenos pero en vertebrados superiores constituye la primera línea de defensa . GRACIAS me ayudó bastante💅🥰

  • @malikzahid6848
    @malikzahid6848 Před 4 lety

    Excellent sir but name of component and cells are not clear.

  • @Ashwin_official
    @Ashwin_official Před 3 lety +1

    So accurately and well explained

  • @drsomto007
    @drsomto007 Před rokem

    I thought it's supposed to be CD4 on the T cell, please explain

  • @vionagunawan5938
    @vionagunawan5938 Před rokem

    Thank you so much

  • @jorgearmandomejiatobar6482

    wonderful work I love it