Toll-like receptor 4 signalling

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  • čas přidán 29. 01. 2015
  • This movie details how lipopolysaccharide (LPS) from Gram-negative bacteria binds to Toll-like receptor 4 to initiate cell signaling.

Komentáře • 66

  • @BillysCards
    @BillysCards Před 7 lety +84

    I'm shocked this video has less than 10,000 views. One of the best instructional biology videos I have ever seen.

  • @tzadokyona8128
    @tzadokyona8128 Před 3 lety +5

    This is probably the best Biology video i have ever seen.

  • @wthitskianna
    @wthitskianna Před 3 lety +3

    I just learned 2 months worth of Immunology in one video. Thank you!!!

  • @UltaGuide
    @UltaGuide Před 5 lety +6

    A semester of struggling already cleared up before 1:30.
    This needs to be seen more.

  • @AreciboBand
    @AreciboBand Před 4 lety +10

    This video is honestly amazing, it deserves way more views that its had

  • @mayaabdalhadi3880
    @mayaabdalhadi3880 Před rokem +1

    Honestly, one of the best animations I’ve ever seen.
    Amazing graphics that simplified this concept, Well done .

  • @danielmaringellipasqui1593

    What an amazing video! It's really sad to realize that it has much less views than it deserves, because it makes clear, in a graphic way, the beauty of our Immune System! Thank you very much for producing this kind of content!

  • @TransportRoutine
    @TransportRoutine Před 3 lety +2

    Ok I just finished watching it and I am in awe!! Insane graphics and great explanation!! Bravo! (very underrated video)

  • @MrMardalock
    @MrMardalock Před 6 lety +2

    This is the best video about tlr4 I've found on the internet,great job !

  • @paulaivanimedeirosdossanto2643

    The best video on immunology.

  • @catescsc
    @catescsc Před 4 lety +5

    Wow. Fantastic video! I was looking for an elaboration on TLRs for a college major’s biology class, and this exceeded anything else I found. Thank you!!

  • @nicolemillwood8719
    @nicolemillwood8719 Před 5 lety +4

    Not all heros wear capes

  • @Sara-ex5qb
    @Sara-ex5qb Před 3 lety +2

    Thank you so much for this simple yet informative explanation.

  • @ayeshaarshad95439
    @ayeshaarshad95439 Před 3 lety +2

    never seen such quality biology video before!

  • @truongtrieutien9010
    @truongtrieutien9010 Před 2 lety +1

    The quality of this video is so good 👏👏👏

  • @SamIdiot
    @SamIdiot Před 5 lety +8

    this is the best video I've ever seen.!!! it's amazing. Thank you so much :D

  • @insiyafathimamoosavi8186
    @insiyafathimamoosavi8186 Před 2 lety +3

    This is such a well-made video! Great job!

  • @josemanuelnegroe9992
    @josemanuelnegroe9992 Před rokem +1

    this video is a masterpiece

  • @michellebraga9224
    @michellebraga9224 Před 4 lety +2

    Wow... breathtaking video! Super fun and enlightening

  • @henrysanchez1779
    @henrysanchez1779 Před 6 lety +12

    Wow! Great video. Really useful, thank you so much

  • @alexandersupertramp151
    @alexandersupertramp151 Před 9 lety +4

    Absolutely fantastic.. please make more of these.. Cheers.. :)

  • @hmh6040
    @hmh6040 Před 3 lety +2

    What a great video! It's very clear and helpful, thank you!

  • @mako5500
    @mako5500 Před 9 lety +1

    It's just amazing! Thank you! Hope you can load more :)

  • @SarahMMorsy
    @SarahMMorsy Před 4 lety +3

    this is amazing, thank you for this experience

  • @AbhaySingh-wi4qu
    @AbhaySingh-wi4qu Před 3 lety +2

    Great video

  • @antoniofratini6293
    @antoniofratini6293 Před 4 lety +2

    Amazing video. Thank you.

  • @shankhamitrapaul6370
    @shankhamitrapaul6370 Před 4 lety +3

    What a work!!It's more than amazing🙂🙂 and helped me a lot....

  • @karlazamora4327
    @karlazamora4327 Před 4 lety +2

    Excellent video, thanks!

  • @rafaelcalderon3681
    @rafaelcalderon3681 Před 2 lety +1

    Mano, este vídeo parece una documental. Esta bien duro

  • @sakshiverma3190
    @sakshiverma3190 Před 2 lety +2

    Very nice video

  • @SpartanTutorials
    @SpartanTutorials Před rokem

    Beautiful animation! Thanks for sharing!

  • @darkblue1423
    @darkblue1423 Před 2 lety +2

    Wow! very well done, just did the job of God knows how many hours of reading text and not getting anything out of it in just 5 minute which is ACTUALLY useful and not making me more confused in compare to other vidz out there!!! Thank you so much, Keep up the great job and PLEASE make more of such informative precise videos ;-)

    • @rahafaltaher4553
      @rahafaltaher4553 Před 5 měsíci

      That's fact the video is very good , but i was have question about your god? You are christians or muslim?!
      I wanna ask after all this hermonize structure and pathway
      How the non-muslim not search and find the truth .
      Allah said in his book (holy Qura'n):
      We will show them Our signs on the horizons, and within themselves-until it becomes clear to them that it is the truth. Is it not enough that your Lord is a witness over everything?
      Surah Fussilat 53.
      I hope you are muslim . Or search about the fact

    • @darkblue1423
      @darkblue1423 Před 5 měsíci

      Hello brother, I'm muslim and that was just a typo, "of" was extra there. I know it well better than you and as also God himself said in Quran, Do not be nosy about the things that are not your business, refer you to that ayah, wish you well and hope you learn the scientific aspect of this video rather than reading other's comments and try to preach under a scientific topic. peace@@rahafaltaher4553

  • @julianajesusdonascimento875

    Congratulations , it is amazing video. Thank you

  • @mafaldapinho9523
    @mafaldapinho9523 Před 4 lety +2

    This is amazing! Thank you so much!

  • @karenbeard7040
    @karenbeard7040 Před 7 lety +3

    Amazing video!!! Thank you for sharing it :)

  • @Miniclipzx
    @Miniclipzx Před 8 lety +3

    This is very clear and fun!

  • @musabzulfiqar
    @musabzulfiqar Před rokem

    Really well done video man

  • @Zitysek
    @Zitysek Před 7 lety +5

    Really helpful! Thank you!

  • @christiancastro978
    @christiancastro978 Před 7 lety +2

    Wow!!, Great work !!

  • @katherinelindstrom6109
    @katherinelindstrom6109 Před 7 lety +2

    Wonderful! Thank you!

  • @joshuasorenson5162
    @joshuasorenson5162 Před 6 lety +2

    That was great! Thank you!

  • @alisadek3411
    @alisadek3411 Před 7 lety +2

    excellent work...

  • @TheBeastNme
    @TheBeastNme Před 7 lety +2

    Nice work.

  • @mroosie7488
    @mroosie7488 Před 5 lety +1

    Super video!

  • @sheebajobanputra4729
    @sheebajobanputra4729 Před 7 lety +2

    Fantastic

  • @annewilson6096
    @annewilson6096 Před 8 lety +2

    Thank you!

  • @cathymiller3086
    @cathymiller3086 Před 7 lety +2

    excellent! thank you!

  • @MeganWhamGMfan
    @MeganWhamGMfan Před 4 lety +3

    bacteria: enters
    innate cells: huh? Who invited you guys your not on the list!?
    adaptive cells: let me deal with these dick heads

  • @DrCharlesParker
    @DrCharlesParker Před 4 lety +1

    Excellent video! Loaded it on my LPS playlist for immunity ed with patients who are treatment failures. Which one of you guys recorded this? Very helpful.

  • @Jana-tb8rw
    @Jana-tb8rw Před rokem

    Amaaazinngggg videooo

  • @abdal-rahmansalous6032

    Perfect👏

  • @immadisarojini2775
    @immadisarojini2775 Před 3 lety +1

    Super

  • @jhannelsmith7619
    @jhannelsmith7619 Před 10 měsíci

    Omg the best

  • @tessacarstairs5998
    @tessacarstairs5998 Před 5 lety +1

    proud for my school :D

  • @madjedatarek9355
    @madjedatarek9355 Před 2 lety +1

    Wow wow wow

  • @momofromatla2318
    @momofromatla2318 Před rokem

    My teacher(med school) put this video’s link on her ppt.

  • @HimanshuSharma-oy9ss
    @HimanshuSharma-oy9ss Před 3 lety +1

    came here after searching for CD14, only to be awestructed.

  • @laceywhite2656
    @laceywhite2656 Před 2 lety +1

    Please give some insight on any knowledge you have on how taxol damages the TLR4 pathway - cipn symptoms are HORRIBLE and doctors advise irreversible- quality of life is too poor. I am on a desperate search.

  • @rachellewis9791
    @rachellewis9791 Před 3 lety +1

    Do all cells contain TLR4?

  • @dogah1620
    @dogah1620 Před 3 lety

    the video is beautiful but it could contain more information :( not enough for med school

  • @rommelalberan5508
    @rommelalberan5508 Před 6 lety +1

    Why you put these gloomy and ominous background music in an educational video???

  • @subinbyclema
    @subinbyclema Před 4 lety +1

    Innate immune system mucosal chemical barrier skin PRR nonself molecule pamps TLR 10 members family LPS TLR4 LPS gram - Bacteria CD14 soluble MD-2 ecto domains TIR domain adapter protein Myd88 NFkB TF inhibitor lkB phopsphorylating IkB innate immnue response inflammatory response

  • @rahafaltaher4553
    @rahafaltaher4553 Před 5 měsíci

    I wanna ask after all this hermonize structure and pathway how can the one become disbelivers in existence of god, and he just simply beleive in darwin theory and that we come from explosion or by mistake?!
    How the non-muslim not search and find the truth .
    Allah said in his book (holy Qura'n):
    We will show them Our signs on the horizons, and within themselves-until it becomes clear to them that it is the truth. Is it not enough that your Lord is a witness over everything?
    Surah Fussilat 53.