Human Immune System - How it works! (Animation)

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  • čas přidán 22. 06. 2023
  • In this animation, we will explain the human immune system with high-quality graphics never seen before. The phagocytosis of macrophages, the formation of T cells in the thymus, and the microbiome of the skin are explained.
    00:20 Skin and microbiome as defense mechanism
    01:18 Mucous membranes with cilia
    01:55 Coughing as a protective reflex
    02:15 Formation of immune cells from stem cells
    03:15 Diapedesis of granulocytes
    03:52 Chemotaxis of immune cells
    04:19 Phagocytosis of bacteria
    04:55 Macrophages as antigen-presenting cells
    06:03 Formation of T cells (thymopoiesis)
    07:35 Cytotoxic T cells and apoptosis
    08:46 Different types of T cells
    09:05 B cells, plasma cells and antibody formation
    11:14 Opsonization of antigens
    11:43 Types of immune cells
    11:58 Platelet formation in bone marrow
    12:38 Hemostasis (blood clotting, coagulation)

Komentáře • 360

  • @May_Day45
    @May_Day45 Před 9 měsíci +483

    Be nice to yourself, and never feel lonely. Cuz billions and billions of your cells are fighting for you and protecting you with their lives.

    • @ThomasSchwenke-knowledge
      @ThomasSchwenke-knowledge  Před 9 měsíci +47

      That's true :)

    • @De_Lune8002
      @De_Lune8002 Před 8 měsíci +27

      ok thats actually kinda wholesome lol

    • @DanielSHIRO
      @DanielSHIRO Před 8 měsíci +11

      I am a multicellular organism

    • @sthnwatch
      @sthnwatch Před 7 měsíci +9

      @@rosegold4 Amen. Behold only some of the awesome glory and wonder of God's marvelous and magnificent creation.

    • @aravindm681
      @aravindm681 Před 6 měsíci +5

      Yes

  • @Puffshroom.
    @Puffshroom. Před 2 měsíci +26

    As a neutrophil, this was very accurate, good job. 👏

  • @cappsnewcarr
    @cappsnewcarr Před 9 měsíci +35

    Terrific way of depicting complex systems visually, and much easier to understand than in books.

  • @user-wj1mg6wz9e
    @user-wj1mg6wz9e Před 9 měsíci +118

    The immune system has never been so epic. Very interesting and nice animation.

    • @ShawnColeman01
      @ShawnColeman01 Před 9 měsíci +3

      Yet it goes into hyper self-destruct mode when a few pollen spores enter the chat, they fight this harmless spore harder than they would ever fight an actual infection. Which is insanely weird to me.

    • @ernestdmayjr9097
      @ernestdmayjr9097 Před 6 měsíci +2

      Right learning in such a fun experience

  • @dimitrimartiny2977
    @dimitrimartiny2977 Před 7 měsíci +26

    What an amazing video! High quality and clearly explained without being too quick!

  • @sewatweaty5549
    @sewatweaty5549 Před 10 měsíci +90

    Oh man I didn't want it to end. That was a good video please do a part 2 thank you.

  • @mdasib4560
    @mdasib4560 Před 9 měsíci +20

    Full video in comment
    In this animation, we want to show the human immune system with images never seen before. We will learn how macrophages, as well as other cells and mechanisms, protect our organism from death every day.
    Our skin, like the bark of a tree, represents valuable protection. However, the skin is also home to countless microorganisms, among other things, nourished and protected by an oily fluid called sebum, which is produced by sebaceous glands. Sebum contains antimicrobial elements that can kill harmful microbes or too many microbes on the skin, creating a harmonious coexistence between skin cells and microbes, a kind of symbiosis. Microbes also keep one another in balance and kill pathogens dangerous to our cells.
    The protective layer of hollow organs such as the nose, mouth, and trachea is a mucous membrane. Mucous membranes possess cilia that move mucus, to which foreign substances adhere, upward into the oral cavity. If mucociliary clearance is not sufficient, an attempt is made to achieve clearance of unwanted particles through coughing. This is done by inhalation followed by a sudden exhalation to remove foreign substances from the lungs and trachea.
    The bone marrow has stem cells and is the birthplace for many different immune cells, which are also called leukocytes. Stem cells divide to form daughter cells, either asymmetric or symmetric. Symmetric cell division results in either two stem cells or two progenitor cells. The progenitor cells divide again and again, so a single stem cell becomes many immune cells or leukocytes. One common immune cell is the neutrophil, and some remain in the bone marrow, while others enter the bloodstream.
    Our neutrophil belongs to the so-called innate immune system and moves through the blood vessels during inflammatory processes. The endothelial cells of the blood vessels have special receptors, leading to a process called diaeresis. Neutrophils follow cytokines, signal substances of other cells, in the connective tissue. Neutrophils' job is to eat bacteria through a process called phagocytosis, and they also produce certain cytokines that attract other granulocytes and cells of the innate immune system, like macrophages.
    Macrophages arrive on the scene before neutrophils phagocyte bacteria and produce signal substances like tumor necrosis factor, which suppresses hunger, causes fever, and stimulates leukocyte production.
    Another type of leukocyte is the T cell, which possesses receptors to recognize antigens presented by antigen-presenting cells like macrophages. T cells are formed in the bone marrow and mature in the thymus, where they develop antigen receptors. Some migrate to secondary lymphoid organs like lymph nodes and the spleen.
    Naive T cells meet dendritic cells in secondary lymphoid organs, which have already had contact with a pathogen and present antigens on their surface. T cells scan dendritic cells for antigens, and if a match is found, activation and clonal expansion occur.
    Cytotoxic T cells, a type of T cell, scan other cells for antigens. If they find the antigen, they induce apoptosis in the infected cell, eventually eaten by macrophages.
    In addition to cytotoxic T cells, there are T helper cells, memory T cells, regulatory T cells, and others. T helper cells work with B cells, which originate in the bone marrow, and search for specific antigens. B cells can activate immediately or present antigens to T helper cells, leading to clonal expansion and the production of plasma cells, memory B cells, and antibodies.
    Antibodies produced by plasma cells bind to antigens, rendering toxins harmless and marking antigens for phagocytosis by macrophages. This process is called opsonization.
    All immune cells originate from stem cells, which develop into progenitor cells and eventually immune cells. Other important immune cells include natural killer cells and platelets. Platelets, also known as thrombocytes, originate from megakaryocytes in the bone marrow and are essential for blood clotting.
    If an injury to a blood vessel occurs, platelets adhere to collagen fibers and each other, forming a platelet plug, followed by the formation of fibrin strands that bind more platelets and red blood cells, resulting in a strong clot.

    • @Lizard_97
      @Lizard_97 Před 8 měsíci +2

      Thank you sooo much! You and author of this video are me surviors! I have only 2 days for first digital presentation and with animation I will be able to attract the attention of my classmates and due to your comment I don't have to hang on every word for translate to my language, which would be difficult since I'm not a native speaker 💃 Have a nice day!

    • @mdasib4560
      @mdasib4560 Před 8 měsíci +2

      @@Lizard_97 glad to see you

    • @Da_learnerREACTS97
      @Da_learnerREACTS97 Před 6 měsíci

      😂❤❤❤

  • @Dandelion_flight
    @Dandelion_flight Před 10 měsíci +45

    Extremely amazing!!! Wonderful animation and spectacular music and clear narration! Thank you!

    • @ernestdmayjr9097
      @ernestdmayjr9097 Před 6 měsíci +2

      It really dives into the difficult part of the body system.

  • @sthnwatch
    @sthnwatch Před 7 měsíci +6

    What an outstanding presentation!
    Thank you sincerely for posting this video. It is excellent in refreshing my knowledge in Human Immune System Biomedicine, and I'm stoked with it.

  • @RockyKhim
    @RockyKhim Před 6 měsíci +9

    Thank you guys for the excellent job! I'm so impressed and glad to see how this immune system works with my own eyes actually. It's hugely helpful.

  • @hojjat5000
    @hojjat5000 Před 11 měsíci +48

    x-cell-ant.

  • @Gaminiheraliyawala
    @Gaminiheraliyawala Před 10 měsíci +9

    Thank you very much Dear Dr. Thomas for this amazing presentation on the subject so precisely, and I have not seen a video tutorial to this depth of detail in the subject of human immune system. God Bless You..... 💐💐🙏🙏

  • @MultiTipsie
    @MultiTipsie Před 10 měsíci +6

    Beautiful! Also simple enough to show and learn my kids about this! Thank you!

  • @duelingsora
    @duelingsora Před 9 měsíci +9

    The information is presented as if it's an Intel briefing before a mission. It has me on the edge of my seat. 😂

  • @abbyclave3661
    @abbyclave3661 Před 9 měsíci +5

    Very informative. Thank you!
    Beautiful animation too.

  • @user-yn5fs5xk5z
    @user-yn5fs5xk5z Před 5 měsíci +3

    A beautiful journey understanding the mechanism of human immune system...thanks for the effort ❤️

  • @patrickbennett439
    @patrickbennett439 Před 10 měsíci +9

    I love being covered in sebuma and half exploded micro organisms! So comforting to know! Thanks

  • @Gumball935
    @Gumball935 Před 10 měsíci +5

    Watching this for my immune system military can get motivation, battle strategies, and train recruit immune system soldiers

  • @Aura._Radiance.
    @Aura._Radiance. Před 3 měsíci +1

    Everything is perfect... The explanation is really impressive, the animation is meticulously done. Thank you 👍

  • @robingaspard
    @robingaspard Před 8 měsíci +2

    Incredible animation! Thank you!

  • @user-oj8co6ny8x
    @user-oj8co6ny8x Před 10 měsíci +7

    Just keep making these type of videos 😭❤️🙏 so that we could be eternal grateful to u for that !!

  • @Geoffsmeg
    @Geoffsmeg Před 5 měsíci +1

    Wow that’s amazing, a real eye-opener! Thank you!

  • @ahmedyacine9108
    @ahmedyacine9108 Před 11 měsíci +2

    Thank you for the qualitative videos

  • @thatboyss5576
    @thatboyss5576 Před 4 měsíci +1

    Great animation. I’m sure many would appreciate this.

  • @achma.learning
    @achma.learning Před 9 měsíci +3

    Beautiful! Thanks for this masterpiece 😄

  • @luismanuelguterres4114
    @luismanuelguterres4114 Před 4 měsíci +1

    What an incredible animation and explanation! I love it

  • @sureelukfeepakphroh8890
    @sureelukfeepakphroh8890 Před 9 měsíci +2

    Great video! Thank you so much!

  • @LeafySpreads
    @LeafySpreads Před 10 měsíci +6

    The micro human body is so amazing!

  • @sruthicherupleri2868
    @sruthicherupleri2868 Před 9 měsíci +1

    Thank you for the beautiful and informative video🙏

  • @hillary.7646
    @hillary.7646 Před 4 měsíci +1

    This is an amazing video!!!! Especially for the visual learners

  • @RajeshSrivastava-fr7qz
    @RajeshSrivastava-fr7qz Před 9 měsíci +1

    Gratitude to You for your great effort!

  • @MarianaTDC
    @MarianaTDC Před 7 měsíci +1

    Whaouh, beautiful and well made animation ! Thanks for sharing

  • @apdalrahman3677
    @apdalrahman3677 Před 9 měsíci +1

    Magic work amazing every thing in the video is perfectly prepared, Thank you very much

  • @kuombokatv3238
    @kuombokatv3238 Před 10 měsíci +2

    🎉 thank you for this peace of information Dr.

  • @AiimsAspirant-ys4iv
    @AiimsAspirant-ys4iv Před 5 měsíci +4

    I was so deeply stucked in that animation that it became very difficult to come out of it . appreciable work .❤❤❤
    Love from India 🙏🙏✌️✌️

  • @etheldames9009
    @etheldames9009 Před 7 měsíci +1

    Thankyou for this video. Very interesting about the immune system.

  • @rebanelson607
    @rebanelson607 Před 8 měsíci +1

    Excellent production!

  • @randinu99
    @randinu99 Před 4 měsíci +2

    Amazing creations of the nature

  • @mijitv2862
    @mijitv2862 Před 9 měsíci +1

    Wow.. Super.. Enjoyed very well the immune system journey. 👏👏👏

  • @gayathrisankar2570
    @gayathrisankar2570 Před 3 měsíci +1

    Best animated video and very helpful and easily understood..👍 unbelievable movements

  • @adityab.v.2832
    @adityab.v.2832 Před 5 měsíci +1

    Fantastic to get deep knowledge of immune systems and producing cells. Thanks from a pharma student.

  • @miraal8
    @miraal8 Před 6 měsíci +1

    Wonderful presentation

  • @user-fi4ep5yo7z
    @user-fi4ep5yo7z Před 10 měsíci +2

    Thank You For Your Precise Pristine Explanation.... I Love This 💗💗💗🍏🍏🍏🥑🥑🥑

  • @sorinapalade9793
    @sorinapalade9793 Před 5 měsíci +1

    Mind blowing presentation!!!!

  • @adiakiyes6354
    @adiakiyes6354 Před 7 měsíci +2

    Sir Thom you're a genius. The best teacher. Many thanks...Keep going.....

  • @BarryAnderson
    @BarryAnderson Před 7 měsíci +2

    Excellent and thank you

  • @didijaja8973
    @didijaja8973 Před měsícem +2

    THIS IS THE BEST VIDEO I'VE EVER COME ACROSS ON IMMUNE SYSTEM!!!

    • @ThomasSchwenke-knowledge
      @ThomasSchwenke-knowledge  Před měsícem +1

      Excellent to hear that. Please share with your friends :)

    • @CatAndRain-kn6lv
      @CatAndRain-kn6lv Před měsícem

      Try Kurzesagt - In a Nutshell but this is also very nice and detailed and also simplified a lot!

    • @didijaja8973
      @didijaja8973 Před měsícem

      @@ThomasSchwenke-knowledge Yes i will

    • @user-ku2cy3pp2d
      @user-ku2cy3pp2d Před 10 dny

      ​@@ThomasSchwenke-knowledgeخليلنة ترجمة حباب

  • @Prof.HanselukasMathLessons
    @Prof.HanselukasMathLessons Před 5 měsíci +2

    Amazing piece of knowledge, right❤

  • @drhussainkhan7369
    @drhussainkhan7369 Před 7 měsíci +1

    Wow!!!! great work it reminded me the whole hematology 😊

  • @user-zj1cc5if9p
    @user-zj1cc5if9p Před 7 měsíci +3

    Plz keep making these types of medical videos ❤❤❤

  • @ebotchilavert7031
    @ebotchilavert7031 Před 11 měsíci +3

    Thanks very much 🥰

  • @user-zu2sm9rs2p
    @user-zu2sm9rs2p Před 10 měsíci +5

    Good job brother! I am speechless!

  • @MariyaJabar
    @MariyaJabar Před 9 měsíci +1

    That was really a great expalanaition with animations keep going😊

  • @mxiaoxie729
    @mxiaoxie729 Před 7 měsíci +1

    Beautiful video!

  • @iamwellandgood7251
    @iamwellandgood7251 Před 9 měsíci +2

    thank you so much i AM SO MUCH GRATEFUL

  • @cooljisoo-cc3oj
    @cooljisoo-cc3oj Před měsícem +1

    thank you so much❤❤❤ now i can say that I understood the science lesson

  • @bushranoor9260
    @bushranoor9260 Před 3 měsíci +1

    Thanks a alot for amazing video😊😊😊

  • @user-cm7pk6hz4h
    @user-cm7pk6hz4h Před 11 měsíci +4

    Very interesting and nice animation❤

  • @casualcasual1234
    @casualcasual1234 Před 9 měsíci +15

    Thank you so much for the animation!! I am self-learning immunology and this definitely helped me visualized and imagine how different leukocytes operate :)

  • @David-dt9tp
    @David-dt9tp Před 8 měsíci +4

    Had fun watching this, felt like some action thriller while being very informative

  • @mirriammwansa8900
    @mirriammwansa8900 Před 24 dny +1

    you are the best thank you

  • @user-mm2th6ez2f
    @user-mm2th6ez2f Před 10 měsíci +4

    My exams next week and it's helping me to understand everything

  • @art._-_-_894
    @art._-_-_894 Před 10 měsíci +3

    Thanks for making these videos 👍👍👍

  • @thirsupitishanti9107
    @thirsupitishanti9107 Před 2 měsíci +1

    Thanks,from thailand for nice and interesting vdo

  • @bigjimmyenglish
    @bigjimmyenglish Před 10 měsíci +2

    Excellent work on the animations. Like and watched

  • @ejameshomecare
    @ejameshomecare Před 4 měsíci +1

    Thank you

  • @user-ul5pt1yb8z
    @user-ul5pt1yb8z Před 8 měsíci +1

    Thanks a lot

  • @mednotes197
    @mednotes197 Před 8 měsíci +5

    this is the best explanation on immune system i have watched so far. thank you for creating this masterpiece! it feels like i'm watching an action movie, and at the same time learning about my body

  • @user-zp7ls1bf4d
    @user-zp7ls1bf4d Před 5 měsíci +1

    Really it’s very very good thank you deeply

  • @doriettprada3446
    @doriettprada3446 Před měsícem +1

    Excelente, muchas gracias

  • @alexayilyildirim
    @alexayilyildirim Před 5 měsíci +2

    What an outstanding presentation and animation. I am studying for a nursing major, and I am visual learning; your channel helps me learn and memorize. Thank you so much

  • @doctor02new
    @doctor02new Před 9 měsíci +1

    Superb indeed!

  • @SimonShababGillVlogs
    @SimonShababGillVlogs Před 11 měsíci +2

    Always amazing 😍 videos

  • @user-pm5vr5xc9y
    @user-pm5vr5xc9y Před 5 měsíci +1

    Thanks i love the video u had work hard bro ❤

  • @SUS1234
    @SUS1234 Před 6 měsíci +1

    Amazing 🤩🤩 many thanks greetings from Egypt 🙏💖😚

  • @ranjanjoshi3454
    @ranjanjoshi3454 Před 10 měsíci +1

    सुंदर सादरीकरण nice presentation thanks

  • @Miscellaneous329
    @Miscellaneous329 Před 6 měsíci +1

    Thx for amazing vdos,it will help in yoga

  • @longho5836
    @longho5836 Před 7 měsíci +1

    Best video hands down ….

  • @adammorrello
    @adammorrello Před 8 měsíci +1

    This music is SO intense lol I feel like a super hero learning about my body getting ready for battle

  • @user-cs3ts8no4s
    @user-cs3ts8no4s Před 6 měsíci +2

    As a medical student, I think that this video is one of the most amazing I have ever seen.

  • @parimalaraoan8496
    @parimalaraoan8496 Před 2 měsíci +1

    This is the best!!!!!!!!!❤❤❤

  • @mouksinesanni6272
    @mouksinesanni6272 Před 5 měsíci +1

    The immun systeme fonction is fantastic 😊

  • @ernestdmayjr9097
    @ernestdmayjr9097 Před 6 měsíci +1

    Such a great video to help learn more in depth about the immune systemin the human body thank you for sharing.

  • @rakhitatla
    @rakhitatla Před 9 měsíci +1

    Thanks a lot brother.. this is very helpful for me for my exams

  • @jaikohn4754
    @jaikohn4754 Před 9 měsíci +4

    Inside human body looks like another world 😮

  • @user-gd4wt6oi7y
    @user-gd4wt6oi7y Před 3 měsíci +1

    I quiet like the dramatic music accompanying the narrative.

  • @vijaykumarm9680
    @vijaykumarm9680 Před 4 měsíci +1

    👌👌👌 so great video..!👍👍👍

  • @wingmanemu3473
    @wingmanemu3473 Před 11 měsíci +1

    incredible

  • @samionita2008
    @samionita2008 Před 6 měsíci +1

    Amazing

  • @arlindaflorescoleto-medica3243

    Awesome!!!!!!

  • @HEALTHYSOULMEDICALCENTER
    @HEALTHYSOULMEDICALCENTER Před 9 měsíci +1

    Amazing 👏

  • @ezatullahhanifi4377
    @ezatullahhanifi4377 Před 6 měsíci

    Tnx alot

  • @bromatonta
    @bromatonta Před 6 měsíci +1

    Amazing!!

  • @chinnuz_03
    @chinnuz_03 Před 7 měsíci +1

    Very interesting animation ❤

  • @user-nw9st3xt6m
    @user-nw9st3xt6m Před 4 měsíci +1

    You deserve billion of subscriber please upload more videos about biology

  • @cibeleanjos3051
    @cibeleanjos3051 Před 3 měsíci +1

    Very good for to study! I am student of nurse, and me help me of lot in classroom...God bless 🙌

  • @sajiruddinsk8129
    @sajiruddinsk8129 Před 7 měsíci +1

    Very good.

  • @user-jd3wm9hc2k
    @user-jd3wm9hc2k Před 4 měsíci +1

    This is the most interesting video i lave vere seen in mi academic life

  • @Chamanlal80367
    @Chamanlal80367 Před 8 měsíci +2

    Awesome 😊

  • @abeehabutt6393
    @abeehabutt6393 Před 7 měsíci +1

    great work ❣❣❣❣❣