Molecular Biology

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  • čas přidán 26. 07. 2024
  • Paul Andersen explains the major procedures in molecular biology. He starts with a brief description of Taq polymerase extracted from the hot pools of Yellowstone Park. He then uses the analogy of the ransom note to explain each of the processes that are required in genetic engineering. He explains how DNA is cut using restriction enzymes and glued using hydrogen bonds. He explains how gel electrophoresis can be used to sort DNA according to length and how the Polymerase Chain Reaction can be used to copy DNA. He finishes with a brief description of DNA sequencing.
    Intro Music Atribution
    Title: I4dsong_loop_main.wav
    Artist: CosmicD
    Link to sound: www.freesound.org/people/Cosmi...
    Creative Commons Atribution License

Komentáře • 286

  • @saciaashe577
    @saciaashe577 Před 7 lety +306

    Your "real" students are literally the luckiest kids ever. Thank you!!!

  • @sarahaghani2252
    @sarahaghani2252 Před 8 lety +79

    Mr. Anderson, I'm really jealous of your biology students for having a great teacher like you. Thank you so much sir!

  • @bellawills2909
    @bellawills2909 Před 8 lety +293

    This channel is where I go to before a test

  • @yehyaaljerjawi3388
    @yehyaaljerjawi3388 Před 7 lety +452

    Our teacher doesn't teach he just shows us these videos

  • @elyseong7518
    @elyseong7518 Před 10 lety +88

    If it wasnt for your videos, I would have been screwed in my AP Bio class.
    I wish you were my real teacher...

  • @peepalfarm
    @peepalfarm Před 5 lety +16

    I wish I had teachers like you for all subjects!

  • @moneyluser5711
    @moneyluser5711 Před 5 lety +2

    Finally a briskly paced video without 30min of useless introduction. Thank you!

  • @galaandding
    @galaandding Před 4 lety +4

    When someone can explain genetics in this simple manner, Someone REALLY understands genetics! Thank you, professor!

  • @WithASideOfFries
    @WithASideOfFries Před 8 lety +87

    Dude. I have a test in an hour and I haven't studied so I'm binge watching your videos and you. Are. A. Godsend!!!

    • @gwenpenaco7506
      @gwenpenaco7506 Před 8 lety +10

      How did that go? Im in the same boat lmao

    • @WithASideOfFries
      @WithASideOfFries Před 8 lety +22

      +Gwendolyn Penaco I somehow did one of the best in my class omg.. Thanks for asking and good luck!

    • @Liamalaing
      @Liamalaing Před 2 lety +2

      @@WithASideOfFries don't suppose you remember the stuff 5 years on? Exam crisis over here 🤣

    • @larafernandes287
      @larafernandes287 Před 2 lety

      @@Liamalaing Same ahahaa I have an exam on Wednesday, can't focus, can't study but this video somehow has been able to catch my attention

    • @Liamalaing
      @Liamalaing Před 2 lety

      @@larafernandes287 mines on Wednesday too, please help 😂

  • @matildaramos4534
    @matildaramos4534 Před 8 lety +5

    Got to admire the sheer effort he puts into his videos

  • @PhoenixFire32
    @PhoenixFire32 Před 9 lety +38

    DNA Ligase is what combines broken DNA fragments. I would not say it is just "hydrogen bonding" as that only exists between the bases. The backbone must also be covalently bonded.
    Good video though.

    • @jazzytorres483
      @jazzytorres483 Před 8 lety

      +I like robots yes im so confused

    • @bonbonpony
      @bonbonpony Před 8 lety +1

      +Sentient Yeah... The hydrogen bonding can only merge two complementary strands together into one double-helix. But it cannot join two helices together into a longer helix. There has to be something which will make the peptide bond between the 3' and 5' ends.

  • @hanahleiabach8128
    @hanahleiabach8128 Před 4 lety

    Using this to help review before a high bio test and this is a LIFE SAVER

  • @gracelee4095
    @gracelee4095 Před 6 lety +6

    THIS VIDEO FREAKING SAVED MY LIFE, I FEEL LIKE I JUST FLEW AWAY AND FOUND THE ENLIGHTENMENT TYTY I CAN DIE IN PEACE NOW

  • @tenasha8
    @tenasha8 Před 10 lety +3

    THANKYOU for explaining Polymerase Chain Reaction so clearly and nicely!!

  • @HaryanaEducation
    @HaryanaEducation Před 11 lety +1

    the way u make the things clear and more easy is just amazing

  • @parthobiswas5696
    @parthobiswas5696 Před 7 lety +1

    Moleculer biology was never been so easy. Thanks to you.

  • @peters8512
    @peters8512 Před 9 lety +31

    "What if I had not taken LSD ever; would I have still invented PCR? I don't know. I doubt it. I seriously doubt it." - Kary Mullis, inventor of the polymerase chain reaction.

  • @saahilthukral
    @saahilthukral Před 10 lety +3

    You are a very helpful teacher, and at most times, even more helpful than my own teacher! Thank you a lot

  • @Jordan-xt6lw
    @Jordan-xt6lw Před 11 lety +1

    Mr. Andersen thank you so much! You have no idea how much this has helped me and how well I understand things because of the way you teach them. Keep doing what you're doing!

  • @ineedcoffee21
    @ineedcoffee21 Před 11 lety +4

    I absolutely love your analogy of the Pachinko machine and electrophoresis! Wonderfully explained! You're awesome, Mr Anderson! :D

  • @oliviagrigaux7088
    @oliviagrigaux7088 Před 10 lety +4

    Only reason I'm getting an A in my AP Bio class are your videos.Thank you so much!

  • @KrazyBean14
    @KrazyBean14 Před 10 lety +17

    You are amazing. You made this sound so simple. Subbed.

  • @DorPeer
    @DorPeer Před 2 měsíci

    One of the most comprehensible biological videos I have ever seen! Terrific.

  • @Mayoran2
    @Mayoran2 Před 8 lety

    Your analogies really helped me get my head around this, thank you!

  • @shaneberrett562
    @shaneberrett562 Před 4 lety

    No joke, about an hour or two of lecture in my class left me confused and then 15 minutes of this video made perfect sense

  • @evelynili7748
    @evelynili7748 Před 10 lety +7

    MAN! You are such an amazing teacher!! WOW...seriously, just awesome. Thank you!!!

  • @samamatoury8253
    @samamatoury8253 Před 4 lety +4

    Thank you, the working of PCR can now easily be understood, thanks to the simple method used to bring it across, brilliant!! I get a lot of help watching your videos, thanks again.

  • @aadil64x
    @aadil64x Před 9 lety +1

    Thanks so much for your time and effort to make these videos to educate us!

  • @kristinmoore1945
    @kristinmoore1945 Před 9 lety +1

    I think you just saved my microbiology lab grade!

  • @mass_oak
    @mass_oak Před 3 lety

    i'm just watching it, couse i have missed this guys. i used watch his video every day when i was in college. definitely brings memories. he is very good explainer.

  • @aelizabethox
    @aelizabethox Před 11 lety +9

    I have been studying a-level biology for two years and these videos have helped me understand so much!
    Keep it up! University is going to be so much easier thanks to watching you!

  • @Frijjazzo
    @Frijjazzo Před 4 lety +2

    Incredibly helpful, thank you for being so logical and clear

  • @specialagentA
    @specialagentA Před 10 lety +1

    Thank you so much for making my life a lot easier whilst studying for a test sick.. :) It would be so hard without you, you are a life saver!

  • @mariablanco3514
    @mariablanco3514 Před 6 lety +1

    Ready for my test tomorrow after watching your vids.

  • @elenp3610
    @elenp3610 Před 7 lety +1

    Your video made the topic make so much more sense, thanks so much!

  • @ericaboyle6735
    @ericaboyle6735 Před 7 lety +1

    Finally I found a great explanation! Thanks mate!

  • @onedgew2780
    @onedgew2780 Před 11 lety +1

    I was skeptical when saw all the comparisons ( 'comparisons are odious') almost could not get thru...but.. you united main concepts pretty nicely. super happy. thanks.

  • @echeekeyp
    @echeekeyp Před 12 lety

    Hey Paul,
    I would like to start from thanking you but again can't thank you enough. After seeing your videos (actually studying) I can say, my thurst for looking more is completed. I salute. Thanks...

  • @katiekay4516
    @katiekay4516 Před 9 lety +1

    This video was really helpful! It would be so good if you could do a video series for A level Biology and Chemistry with snippets of your own interesting comments and extra information- that would be great :)

  • @anatasic9658
    @anatasic9658 Před 9 lety +1

    thank you so much! you are extremely helpful! i enjoy watching your videos after my lessons and i honestly understand the material so much better! you are blessed!

  • @Wesley_semeniuk96
    @Wesley_semeniuk96 Před 3 lety

    This channel has helped me through my biology course !

  • @RandyPhrs3hh
    @RandyPhrs3hh Před 11 lety +1

    Thank you..I have a test tomorrow and this clarified the information very well.

  • @SeeWayDown
    @SeeWayDown Před 9 lety +2

    You're one the greatest teachers, looks like you have great passion. Keep doing it!! :)

  • @farhanaahmed7163
    @farhanaahmed7163 Před 10 lety +1

    Really appreciate you taking the time to make these videos, it helped make the difficult easy, thaank youu!!!

  • @beatrizalves1627
    @beatrizalves1627 Před 5 lety

    YOU JUST SAVED MY GRADE THANK YOU

  • @JeannetteHommel
    @JeannetteHommel Před 4 lety

    you deserve the world Dr. Andersen

  • @mehio1075
    @mehio1075 Před 6 lety

    Mannn Paul Anderson is just the best. I love these videos they're so helpful.

  • @GarrisonBoysHighSchool9941

    your teaching method is fabulous i realy learn from it. thanks a lot.

  • @optimaluse
    @optimaluse Před 11 lety

    Thank you. You are very clear in your presentation and very informative. Your videos are very much appreciated!

  • @rrintan9140
    @rrintan9140 Před 8 lety +1

    Thaaaaaaank you! It helps me a lot to get through my upcoming med school entrance test :")))))

  • @xxdeathwingxx2221
    @xxdeathwingxx2221 Před 8 lety +4

    Forever No.1 CZcamsr!!!!

  • @johnsontan345
    @johnsontan345 Před 6 lety

    Your videos are saving my exam tomorrow. You have my subscription.

  • @cciccone61
    @cciccone61 Před 3 lety

    You have a gift of simplifying the complex. Dear Lord this is good information!

  • @exeg91
    @exeg91 Před 10 lety +1

    Amazing video! It's very clear and helpful, thanks!

  • @junkomine798
    @junkomine798 Před 9 lety +1

    I enjoy watching Mr. Andersen's videos very much!. You're a true molecular biologist, and remind me of Alton Brown (from Food Channel) who is also excellent on explaining everything from science point of view.

  • @NerdyGeisha
    @NerdyGeisha Před 11 lety

    Pachinko, woo! Thank you so much for all of your videos (and your pachinko analogy, that really helped) :D

  • @veronikadolgushina165
    @veronikadolgushina165 Před 3 lety

    This video is so good and clear! Thanks a lot for such a great job!

  • @phyaunna1329
    @phyaunna1329 Před 7 lety +1

    Thanks it's so much clearer for my exam after tomorrow :D

  • @MMaquishon
    @MMaquishon Před 10 lety

    I can't thank you enough!!! I LOVE your videos, they have helped me so much!!!

  • @platinum01
    @platinum01 Před 7 lety +1

    Wow, this is a VERY helpful video! Thank you.

  • @danahbourhamah5458
    @danahbourhamah5458 Před 10 lety +1

    You're an awesome teacher seriously ! *applause*

  • @fedup4190
    @fedup4190 Před 8 lety +12

    Thank you soo much!!!

  • @ghazalehghiassi
    @ghazalehghiassi Před 10 lety

    Best teacher! so simple and practical!

  • @mouradzaghloul4282
    @mouradzaghloul4282 Před 5 lety

    Absolutely incredible! Thank you!

  • @erikargap3285
    @erikargap3285 Před 3 lety

    Thank you for sharing! Your video provides a visual summary of this topic, for my Microbiology course that is online :)

  • @mightymush
    @mightymush Před 8 lety +1

    Very well explained, thanks.

  • @m.k.saunders3998
    @m.k.saunders3998 Před 6 lety +1

    thank you so much, sir. this makes so much more sense....

  • @badamkhandnamkhai8558
    @badamkhandnamkhai8558 Před 7 lety +1

    Molecular biology is really hard to understand. Thank you dear sooooo muuuuch

  • @parischanel16
    @parischanel16 Před 9 lety +1

    Thank you SO much! Hoping for a 5 tomorrow 😓

  • @hadeerrashad5486
    @hadeerrashad5486 Před 5 lety

    Thank you very much for making this video !!!

  • @skyblue2121
    @skyblue2121 Před 7 lety +1

    Thank you. Great explanation!

  • @TheSashalea
    @TheSashalea Před 10 lety +1

    Thank you so much! I love your videos! You are so smart and make it so easy. You are better than my professors. You explained it better than my professors in the master level! You should teach us!

  • @bigbrotherbear7912
    @bigbrotherbear7912 Před 3 lety

    this guy is absolute lad when it comes to teaching

  • @Sweetiegirl18
    @Sweetiegirl18 Před 12 lety +1

    im studying to the national ap bio exam tomorrow. thank you!

  • @marekcm1882
    @marekcm1882 Před 10 lety +8

    You get like because of the subtitles. Thx :)

  • @LK-cc4uj
    @LK-cc4uj Před rokem

    You are a damn good teacher my friend. Thank you for freely sharing your knowledge!

  • @richidubey1056
    @richidubey1056 Před 6 lety +3

    You hope that's helpful?????
    That's way much more helpful than anything. We have two teachers who are really highly educated to teach these stuff. I tried my best to learn from them and I couldn't understand shit.
    You are a legendary teacher. The eat you explain and link various things and use all those examples. I hope everyone gets to learn from awesome teachers like you.
    Keep up the good work.

    • @richtxn47
      @richtxn47 Před 5 lety

      I totally understand what you mean. My second chemistry course was taught by a Ph D in Chemical Engineering; he could not grasp why learning the material was so difficult for his classes. The University's BEST chemistry professor only had an M.S. but he had many awards for his teaching skills. My college years in Chemistry coincided with the realization that just because someone has an advanced degree does not mean they can adequately explain it to anyone.

  • @Rosaleye
    @Rosaleye Před 9 lety +1

    You are amazingly great! Thank you so much for your great videos!

  • @nabilaaten9950
    @nabilaaten9950 Před 3 lety

    you are my saviour . Thank you so much for the good explanation

  • @richarddisney1664
    @richarddisney1664 Před 10 lety +24

    Shouldn't you include DNA Ligase as the "glue" in addition to hydrogen bonding?

    • @SS8styles
      @SS8styles Před 10 lety +5

      from my understanding, ligase seals the nicks along the axis of the double helix between nucleotides, due to the formation of okazaki fragments. Whereas H-bonds actually hold the two strands together, perpendicular to the axis of the double helix. Metaphorically, it might be misleading to think of both as "glue" especially in the context he was discussing, namely, applications of molecular biology. You need to open up the DNA to use it for practical applications such as PCR, so H-bonds are what you need to un-glue to achieve this. On the other hand, I don't think you would need to undo what ligase does b/c there's no practical utility in reproducing okazaki fragments. But don't take my word for it, i aint got no phd.

  • @marylouis1913
    @marylouis1913 Před 5 lety

    Amazing! The best biology teacher ever :'[ I got the acceptance to study bio but, Damon that , now i want to study molecular biology :(

  • @docsif
    @docsif Před 11 lety +1

    Brilliant job, thanks!

  • @JeyShuffle
    @JeyShuffle Před 11 lety

    A-level biology exam tomorrow, thanks so much

  • @stevenpan8819
    @stevenpan8819 Před 3 lety

    Best teacher ever.

  • @katiehostetler2673
    @katiehostetler2673 Před 6 lety +1

    Thank you so much mr. anderson

  • @suprateekat5338
    @suprateekat5338 Před 9 lety

    This is fantastic!!

  • @dantonbm
    @dantonbm Před 7 lety

    Actually I'm Brazilian but your videos help me a lot. Thanks!

  • @ualasraaschpagel3006
    @ualasraaschpagel3006 Před 8 lety

    Good video. Very clear.

  • @Zeras5474
    @Zeras5474 Před 3 lety

    Omg that was perfect!!!! Thank you a lot 🙏

  • @EternalAlexandra
    @EternalAlexandra Před 3 lety

    loved it! thank you! amazing teaching

  • @gonitya
    @gonitya Před 10 lety +5

    best teacher in the world .. :)

  • @emionisann933
    @emionisann933 Před 9 lety +2

    Thank you for what you re doing:d

  • @edwardwynne
    @edwardwynne Před 4 lety

    really awesome vid bro! good shit

  • @Pavithraloganathan_1993
    @Pavithraloganathan_1993 Před 11 lety

    ur soo cool!!!no one can explain things better than you :) ur the best !(y)

  • @tatu5tatu
    @tatu5tatu Před 10 lety +1

    Thanks so much for your explanations, but I would like to know if you have a video of translation of RNA into ribosomes, for example the three steps of translation: initiation, elongation, and termination.

  • @MultiApodyopsis
    @MultiApodyopsis Před 12 lety

    You hope its helpful? You are possibly the most helpful person on youtube!

  • @hannahbickley9
    @hannahbickley9 Před 11 lety

    Thank you so much ! This helped a lot!

  • @ryansergas3894
    @ryansergas3894 Před 9 lety +4

    FOR SCIENCE
    Thank you.

  • @yasminmalik638
    @yasminmalik638 Před 3 lety

    Brilliant video...thank you.

  • @sritharshanavet5310
    @sritharshanavet5310 Před rokem

    Awesome teaching! Thank you so much...You are a very good teacher I can see that😇 in your way of teaching....