Pharmacology - Anticoagulants and Antiplatelet Drugs FROM A TO Z

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👉 VIDEO GUIDE 👇
00:05 - What Is Hemostasis ? Platelet Aggregation and Coagulation Cascade MADE EASY
08:49 - Antiplatelet Drugs MADE EASY
1. Thromboxane A2 inhibitors:
- Aspirin
2. ADP receptor inhibitors:
- Clopidogrel, Ticlopidine, prasugrel, and ticagrelor
3. GP IIb/IIIa inhibitors:
- Abciximab, eptifibatide, and tirofiban.
And Dipyridamole and Cilostazol.
14:23 - Anticoagulant Drugs MADE EASY. Divided to 4 main categories:
1. Activators of Antithrombin III.
- Unfractionated Heparin.
- Low Molecular Weight Heparin ( LMWHs ) and they include:
- enoxaparin, dalteparin, tinzaparin and Nadroparin.
- And the synthetic pentasaccharide, Fondaparinux.
2. Vitamin K antagonists: Warfarin ( Coumadin ).
3. Direct Thrombin inhibitors. Parenteral and oral agents:
- The parenteral agents include:
- Bivalirudin ( Angiomax )
- Desirudin ( Iprivask )
- Lepirudin ( Refludan )
- Argatroban ( Argatroban )
- And the oral agent is Dabigatran etexilate ( Pradaxa ), and It's antidote Idarucizumab ( Praxbind )
4. Selective Factor Xa inhibitors.
- The parenteral agent: Fondaparinux ( Arixtra ), and oral agents: Rivaroxaban ( Xarelto ) and Apixaban ( Eliquis ).
29:00 - Thrombolytic Drugs ( Fibrinolytic drugs ) MADE EASY. This category includes:
- Alteplase ( Activase ), Reteplase ( Retavase ) and Tenecteplase ( Tnkase ).
- Urokinase ( Kinlytic ), Streptokinase and Anistreplase ( Eminase).
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