Xiaowei Zhuang (Harvard/HHMI) Part 1: Super-Resolution Fluorescence Microscopy
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- čas přidán 30. 07. 2024
- www.ibiology.org/biophysics/s...
Zhuang begins her lecture by explaining that the resolution of traditional light microscopy is about 200 nm due to the diffraction of light. This diffraction limit has long hampered the ability of scientists to visualize individual proteins and sub-cellular structures. The recent development of sub-diffraction limit, or super resolution, microscopy techniques, such as STORM, allows scientists to obtain beautiful images of individual labeled proteins in live cells. In Part 2 of her talk, Zhuang gives two examples of how her lab has used STORM; first to study the chromosome organization of E. coli and second, to determine the molecular architecture of a synapse. - Věda a technologie
I was so surprised to come across this video that found out you were one of my students in Suzhou High School in 1985.
chiNAZI DETECTED....
Cool! She is a very highly regarded scientist, and helped create a nobel prize winning technology. Many people think she should have been awarded as well, but it is limited to 3 people and hard to choose which are most deserving.
This video is exactly what I was looking for. I had trouble to understand super resolution microscopy, and now I think I understood the core concept of it. Thank you so much!!
Thanks for breaking this down so simply. It is amazing just how detailed the images are and humbling to realize that each of the cells imaged are so vastly complex and compact. Exciting to imagine how much further this can be improved. Thanks again I really felt like I learned a lot.
Fantastic presentation. Really impressed by the clarity and usefulness of this information. Thank you very much.
Thank you; one of the best science channels on the Tubes
Many thanks for this great presentation, very clearly explained.
But now we just need to win the lottery to get a storm instrument to play with.
A very good, and coherent explanation with plenty to take away for even a layman such as myself! Thank you! rc
I am only 6 minutes in and already I approve of your presentation. I am a layperson who studies the sciences purely for self enlightenment. Unfortunately I was unable to pursue my passion for a science career in my youth due to financial issues. Nicely done and very informative.
LARP.
Great promising Technology,great presentation.Thank you.
Really beautiful presentation!
Thank you so much for amazing presentation. It was really intuitive ... And you have good humor :) ;) ...
Great presentation and great explanation.
thanks really beautiful Pf.Zhuanga lot.Your video is really help!
Thanks for uploading this!
Thank you - very helpful!
still mind-blowing, such elegant method
Awesome talk. Thank you
THANK YOU!
thank you for the great class. :D
Very impressive. Only one question, why comic sans font? There are hundreds of good fonts out there.
fantastic!
Very impressive presentation. And such a beautiful lady with such a magical laugh.
It will be good for cryonicists and I have the same disease than Howard Hughes almost. But I hope this tool will widely be used by scientists in the future to see if we can save our own lives. like in anti aging. all around the world. in germany, in france, in china, in canada, in usa etc..
for cryonicists we will need more than that, more than 10 NM resolution, and not only cells outsides the bodies, but inside the bodies like in a MRI, while the patient is living or not, like frozen or where there are movement. This tool was implemented in 2006 I think or so, and perfected in 2018 or 2016. Let's put another 100 years and we will be able to see in a resolution of less than 1 nanometers, everywhere inside living bodies or objects with movements inside.
we will need scanners of 0.1 nm of resolutions for living patients.
really amazing
Awesome!
You are genius. Hope to have a chance to work in your group.
Any chance that a lecture on Super-Resolution Microscopy could be posted as a video in High Definition? 480p max... seriously?
We weren't filming in HD at the time we recorded the talk. However, check out www.ibiology.org/ibioeducation/taking-courses/ibiology-microscopy-short-course/super-resolution-microscopy.html and the videos here www.ibiology.org/ibioeducation/taking-courses/ibiology-microscopy-course.html as most of them were in HD.
Isn't that all Green Screen that you are doing? Couldn't the background be incorporated at a higher resolution and the video rerendered at 720p or 1080p? I realize that the foreground lecturer will not be in HD, which may look a bit weird, but the important images in data will be more clear.
Use a looking glass!
小威老师，我的偶像！
awesome
2:57
I think it's scanning probe not spinning probe.
super
The scale of sizes going the wrong way down drives me crazy.
still unsharp imges and the resolution cannot be better then the wavelength of the fluorescent light
Genius
14:52
tip: watch in 2x speed
good tip..**
1.25 is better
I prefer 0.5x
Hahaha, I did the same thing and then saw your comment as I was about to post the same thing.
Holy Shit, this is 13 year old tech? Is there a movie being made about images from the molecular universe?
chinese chosaky, sage chini
Comic Sans?! WAT?!!1
why not? lol
I immediately closed the video.
480 p here sucks.
at 1.25x speed she doesn't sound drunk
Robbed of Nobel.
Exactly! Robbled of Nobel! Extremely unfair! The Nobel price is totally nonsense and ridiculous!
one of the worst speaker. slow words, inadequate aggressive intonations, lack of facial expressions. almost impossible to perceive such presentation, if you are not a masochist, of course.
awesome