My mom passed away from Alzheimer's in Feb..6 weeks later out of the blue my "healthy" step father died from Cruetzfedlt Jacob disease. Until that week I had never heard of it let alone that it was possible to have this human form. It hits out of the blue up to 10-15 yrs and kills almost immediately. They were deer hunters both of them. They were active and ate healthy. This yesr has changed our lives and to go back home will never have that real meaning again. I turned 43 two days ago and Im absolutely lost. I appreciate your shows Joe. Thanks for your work and the amazing guests you share with us.
@Es1911sumware That is awful. I have a freezer full of deer meat I am thinking about tossing because I did not get them tested. I also have so consumed the heart of one that was positive so that is worrying me but all I can do is move forward with the best precautions I know. From my understanding it gets in the plants as well, so even vegans are not safe.
Not mention being an engineering major and being forced to take an unnecessary and useless liberal arts class to support their program. That is just plain old, common, thievery.
If it ever comes up in your class small group discussions, this might be an interesting avenue of discussion: "There is increasing concern about the troubling possibility that blood or blood products, vaccines and other pharmaceutical products could spread the agent of variant CJD (vCJD) worldwide, especially in countries where BSE has not yet been reported. Bovine derived materials involved in the production of vaccines and other pharmaceutical products could represent a way of potential transmission of the disease. Moreover, the possibility that human blood and plasma could be a vehicle for the transmission and spread of the disease have led to a number of donor deferral policies aimed at minimizing the risk of accepting a blood donor who might be incubating the human form of BSE. In addition, blood fractionated products such as albumin are used as stabilizers in the production of vaccines and recombinant pharmaceutical products. There is, therefore, a need to ensure that regulatory authorities with limited resources can have reliable information when making their risk assessment and evaluation of product safety to prevent the transmission of TSE to human via biological and pharmaceutical products." www.who.int/bloodproducts/tse/en/
Smart people always are so modest. "I know some experts" while refusing to refer to himself as an expert. Seems that stupid people are quick to act like they know everything.
DreamBeatsBakery I think Einstein described a similar thing, but on the scale of humanity. As the fire of our knowledge grows larger, the things we know we don’t know increase as the area illuminated, and we also realize as the circumference of this illumination grows, how much we are in the dark.
Are you insinuating that there is a Waco, Wisconsin? Because there isn't... Also if you're not insinuating that there is a Waco, Wisconsin, I don't know why the fuck you felt it necessary to say some shit totally out of left field about an issue I suspect you know nothing about.
It's not totally unknown man. I live in South Carolina and have heard about it for years. Now given I'm a deer hunter so that's probably why. One of the many things I like about Joe is that he's a hunter/outdoorsman.
Scary shit, I've been hunting in WI for 20 years and i can remember it starting with just a blip in the middle of the state and now a good 2/3 of the state has cases of CWD. Hell, he didn't even mention that penned deer can infect wild ones just by touching noses through a fence. Scary shit...
The British have done studies of appendices and tonsil tissue in an attempt to determine exactly how extensively vCJD (Mad Cow) may have spread in England. The results were very frightening. However, no one knows how many infected humans will actually develop the disease.
The terrifying thing about these prions are why they are so resilient. Proteins can be folded in a countless number of ways. Some of these folded states are more thermodynamically stable then others. It's not exactly the same thing, but it's similar to why carbon monoxide is so dangerous as it binds more efficiently to hemoglobin then oxygen does. In fact, part of the reason hemoglobin is so good as a transport molecule is that it's not perfect, it's not entirely stable.. it's what allows that oxygen to be let go of. Disease prions are kind of like that. The main difference being that these highly stable folded states are so stable that they can't be unfolded by normal processes and they're also so stable they can't actually be used to do anything. This basically makes them just continually build up as the body can't do anything with them and can't break them down to get rid of them. That makes them exceedingly hard to break down and gives them half-lives many times longer than normal. It's also what makes them so resistant to heat as it takes a lot more energy than normal to denature the proteins, and even more than that to destroy them. That's not the worst part though.. the worst part is that the damn things work like Ice 9 from Cat's Cradle. Every normal prion they come in contact with spontaneously misfolds itself into the new highly stable but otherwise diseased state. It's a terrifying prospect because it means that you just continually produce more of the terrible shit until you go mad and die, leaving behind a body filled with the resilient shit. It's like if Ice-Nine didn't immediately cause you to freeze solid but instead froze you so slowly that you had a few months of the crystals stabbing into your insides and into your brain before the comfort of death finally saves you from the pain.
life is a fragile thing we can we wiped from this planet in the blink of an eye if anything destroy's mankind some strange disease is what my money's on.
For those of you saying that there isn’t any infected deer because you get your deer tested and they show no signs of infection, if you watch the whole video the biologist explains it can take years before any visible symptoms appear and not all results are accurate when look testing for CWD
Bryan Richards would make an excellent university professor! He explained things so clear and concisely with being pretentious or wordy. He's instantly likeable.
Depends on the species. For mammals, yes, it is usually bad. But for fish and reptiles, it is a good thing and helps the strongest of the young to grow faster.
I had a patient once with CJD. They seemed like a normal patient with dementia but they were in their late 30s or 40s. However, because i knew that they had CJD it seemed so much more eerie and odd. It was a once in a lifetime patient
That Shit was pretty big in the early 2000s in the UK and Germany. They downplayed it and it was forgotten after some time. The media coverage was pretty big back then.
Not gonna lie...Joe has created a really cool job for himself here. He literally has interesting conversations with (mostly) interesting people from all varieties of life.
Yes BUT its not spread-able to humans yet but they can evolve at anytime or even some1 take 1 and experiment on it and try and spread it to humans, ones things for sure is that they wouldn't say anything imo if they didnt think itl spread to humans at a point
This happened in like 1994 when I lived in Wisconsin. They would set up orange markers on corn fields. That was a green light to put down as many as you could and DNR would burn them. My money says this was intentionally created in a lab in America. They just created GMO mosquitoes that are infused with some biological gene to eradicate themselves.
@M S Possibly, especially since it's probably NOT prions causing the TSE infections, but simply a byproduct of the infection, A lot of evidence points to Spiroplasma, and it has been proven that up to 10% of cases have no prions involved. "Spiroplasma biofilm formation explains the role of these wall-less bacteria in the pathogenesis of transmissible spongiform encephalopathies (TSEs). Spiroplasma embedded in the biofilm polysaccharide matrix are markedly resistant to physical and chemical treatment, simulating the biologic properties of the TSE agent. Microcolonies of spiroplasma embedded in biofilm bound to clay are the likely mechanism of lateral transmission of scrapie in sheep and chronic wasting disease in deer via soil ingestion. Spiroplasma in biofilm bound to the stainless steel of surgical instruments may also cause iatrogenic transmission of Creutzfeldt-Jakob disease. Sessile spiroplasma in biofilm attach to the surface by curli-like fibrils, a functional amyloid that is important for spiroplasma entering cells. Curli fibers have been shown to interact with host proteins and initiate formation of a potentially toxic amyloid that multiplies by self-assembly. In TSE, this mechanism may explain how spiroplasma trigger the formation of prion amyloid." academic.oup.com/jnen/article/73/2/104/2917565
I am in Wisconsin as well. I don't know if god is real, but if god was real this is what would happen when sick humans go around bragging about the size of deer they murdered. Deer are one of the most beautiful and peaceful animals.
Living in Wisconsin I can say that all my friends who hunt say this a really bad problem that could boil over due to the insane amount of deer here in Wisconsin.
You need wolves and Coyotes. Here in CT the deer were out of control and everyone complained. The coyotes came in and have done an excellent job of culling. Now people complain about the coyotes. You cant win
benjovi55 ... we have a few counties affected here in WV too. The only answer is to offer mass hunting and tagging these deer. The transmitting of this disease will get worse until we take some drastic steps to cull the population.
I'm in NJ near Easton PA and I'm near a lot of hunting land. Tonight, my brother mentioned this condition after there was a deer right in front of our house look at the outdoor cat. It wasn't scared at all and we were talking on the porch 8-12ft away. I spoke up a bit and it still didn't move. I do remember seeing deer doing this last year too!
This is one of those things that is technically "possible" to fix, but would require so much perfect planning, fencing, culling, and control over every deer it is essentially impossible
when CWD passes to people, they will say-"this is a new disease, we did not know about it and did not assume that this would happen, it is impossible!" But in fact, they could have prevented it 5 years ago.
@@budshakebob3431 There are plenty of professional hunters and some countries are even using their armies for this. So insane people like Nugent aren't really the only option.
Samurai Jack Ted Nuggent is an idiot. You don't have to be a liberal vegan that's never killed a deer to understand Ted is crazy. Stop acting like you know someone you have never met and making assumptions if you don't want to look like a fool.
so Umbrella will come to pass through the merging of these corporations feeding cattle to cattle...none of which will stop...long after this thing jumps species to humans...
They keep bringing up possible human transition, but I’m more interested in how or if it can affect predators that hunt these deer, or possibly other herbivores that come in contact with infected waste or even a water supply.
Gotta thank Joe for bringing this critically important topic to his worldwide platform. CWD has been on the DNR'S radar for at least 20 years. There are new cases of discovered every year but we've been able to for the most part keep it out of the northern herd here in WI. It's still something that is in the back of all of our minds here who are deer hunters.
We had numerous white tail die from this the last two years in Nebraska. It's weird how the infected deer act as well. Lethargic, not afraid of people and act almost as if they are just walking around without a rhyme or reason. Scary stuff makes us hunters think about how our meat may be infected around the area.
"When Ted Nugent was on the podcast he downplayed the consequences and effects of something called CWD" You can always count on Ted Nugent for his extraordinary insights.....
@@joblo1978 Sure thing bud. Next time don't lead with this trash "Right. Because all scientists agree, all scientists are never wrong, biased, or greedy, and science never refines itself, And, unless you’re a scientist, you know nothing. Not all info on CWD from scientists corroborates."
Dam dude you a sheep willing to follow what ever some with a lab coat will tell you. Yeah that right don’t think and put in your own research and experiments just follow the trend.
@@BryanTheHunter Molecular biologist research chemist Ted is not. CWD is like mad cow disease on steroids and would cause non familial SCJD in humans. Dont listen to Ted, hes cabal and his job is to downplay CWD so a bunch of second amendment supporters get killed by this disease. Ted's a fucking idiot, not a scientist.
Yeah right, you pussies can't survive without delivery food and video games. Your not killing shit cause all your guns are downloaded. You guys are the first to to die and have your resources taken.
Es1911sumware It appears that you are well educated and have a personal experience with Jacobs desease, that’s great. My point was that the biologist clearly explained what CWD is and capable of doing. I am coming to you from an academia point of view. And no, I will eat the deer, always have.
Es1911sumware clearly you are biased because of personal experience, I get it. But the I formation the biologist put out about the actual desease is accurate.
Es1911sumware how are you able to determine that they are lobbying of 1 hr of pod cast? Seems like you have them beat on Knowledge, do you have your own podcast I can listen to?
@@Essumwarewhy are you convinced it isnt happening ? I dont trust the government, but how much profit would these guys be making off of this lmfao seems like a super random thing to have a conspiracy over.
UncleRucus I honestly don’t really give a shit 😂 I just thought his response was funny cause it was something a 12 year old would put. This disease has been around for a long time and in my area it’s been here for a long time. So it doesn’t phase me tbh
My mother died of Creutzfekdt-Jacob Disease, sudden onset, in 2009. It's a horrific way to watch someone waste away. TSE, the prion's in the brain fold, which is sudden and fatal.
As I posted above, I have a friend that died of Creutzfekdt-Jacob Disease last year and I have a client who also has a friend that recently died of this as well. What are the odds of it only killing 300 people in the US a year. Im thinking its much more prevalent. We are not being told because no one really knows how is is contracted. Because it may take 40 years to kill a human I feel there may be no urgency to find a cure. One thing for sure, I will never eat deer after hearing this podcast.
Reindeer herds range from Lapland in Norway, Sweden, Finland, and through Northern Siberia. The loss of those herds would be catastrophic to the herders who depend on them for food, shelter, and clothing.
All I will say is this. I worked with a PhD researcher specialized in CWD and worked exclusively in CWD research. He contracted CJD, the human version of CWD. Quite the coincidence as he had no other exposure.
@@howardman3926 no its not. rates are steadily increasing. could be due to better ascertainment/ diagnosis. and there are case clusters in different parts of the world. public health lies when it says that its a consistent 1-2 in a million disease.
lompockid we need to bring deer mental health awareness to the public as suicide rates are high. Only logical explanation as to why there are so many deers jumping infront of cars
im a bald biologist from the institute of bald sciences in madagascar, im not bald myself, what that means is that i study bald people for a living, their habitats, everything about them, check this out: it has been proven that when in inminent danger, bald people sometimes use the reflection of the sun on their heads to blind their enemies and gain a situational advantage also called gaining a bald initiative also flies never land on their heads, ever, and judging their age is at least 70% harder than other groups of people more public money should go towards the study of bald people, they are trully an amazing bunch
We still feed the rendered cow parts to the other cows. And don't think you get off the hook with 'free range' either. Cow feed without rendered cow in it is more expensive so almost no one uses it. This could explain the growing number of dementia and Alzheimer's we are seeing. Like everyone grandparents have that shit, sadly including my own. Its Horrific. If we are going through this to save 4$ a bag on cow feed its not worth it.
I work as a disease investigator and this scares the shyt out of me. Your'e telling me an infected deer that's incubating can test negative but still transmit infection for 3 to 6 months? Man thats worse than syphilis lmao
Read Deadly Feasts, it explains everything he's talking about. Fore tribe in Palau New Guinea were cannibals, which is where first cases of Kuru occurred. Kuru means "laughing disease", which is what my momma did; she had a few days of uncontrollable laughing. This disease is horrific.
Azzury Street you're wrong. The women of the Fore tribe were starved by their husbands, so they had to resort to the eating meats of the other females who died. The vital organs were choice, fatty meats, and unfortunately the brain is where Kuru (CJD) resides. You think you're being funny, but you're talking out your ass. I sure hope that you or a loved one never dies from this horrific disease.
Hillary Clinton also has Kuru, laughing fits and a gaping hole in her tongue combined with all her connections to human traffickers and cannibals enthusiasts/pedophiles
Ramon Almeida we donated her brain to the Prion Center in Cleveland Ohio, which was THE only was to 100% confirm CJD, and which type. Hers was Sudden Onset, which had been laying dormant for years. Thank God it was not familial or from eating wild game, or mad cow disease.
I used to hunt antelope in Alberta 20 years ago. The wildlife conservation officers would check recent kills for visual signs of wasting disease in these populations also. It was a relatively new phenomenon 5-10 years prior to the first observed cases. At that time it was suspected to be due to a lack of natural predation and a reduction in wilderness areas for food sources. However, indigenous populations in southern Alberta used to tell stories of warriors that developed a "madness" from eating to many Buffalo skulls; which was a prized food source due it being a very rich source of fat and protein. So, BSE may have been present in the environment long before cattle were brought to North America. My understanding of the pryon is that it can survive in range of 100's to 1000's of years.
Thanks for the great presentation. In 2002 CWD broke out less than a mile from my family’s tree farm in South-West Wisconsin. We have been working with both state and federal agencies regarding this problem ever since. While there is no doubt it is a problem, it is not the disaster it was first claimed to be. The epidemiological models that predicted a collapse of deer populations not only in Wisconsin, but nationwide were a bit exaggerated to say the least. As we approach 20 years experience with this disease we are seeing the emergence of animals that are more tolerant of the ravages of this disease. This was to be expected. The differential survival of more resistant animals propagated their genes in greater numbers at the expense of the most susceptible. This has resulted in a drift toward a population of more disease tolerant animals. This is not to be confused with resistance or immunity. The animals still contract the disease and die from its effects but at increasingly older ages. Considering the average male whitetail deer has a natural life span of 6-7 years in the wild, even a modest toleration of the disease mitigates its effect on reproduction rates fairly quickly. Wyoming has seen a similar trend over the years as well. Still the captive animal farms are the primary risk perpetuation this disease. Montana took the steps early on to outlaw the farming of game animals and it worked fairly well, yet we are now seeing the first cases moving up from Wyoming.
@Christian Slater or maybe having learned some useful critical thinking skills in the field they found it interesting and attributed that interest to said learned skills?
Lol.... yes. Gamers leave your mother's basements and teach the world the wealth of knowledge you've gained from pre-programmed outcomes in controlled situations
Well I heard an interesting tidbit out here. I heard that bone meal was brought here from Britain just before they discovered their mad cow problem, and gave it to cattle here!
Love the diverse and informative topics...I've watched a bunch of your shows but I subscribed because of this one...This is better public service then most news stations. Taking the time to cover the subject so that people can make informed decisions on how this matters to them. LOVE IT!
My family has a whitetail deer farm in western iowa where there are no documented cases. My grandfather has had every deer that dies tested since 2000 and not one has had the disease but I'm starting to worry with the spread lol
i'm always surprised how much Joe is able to follow intellectual discussions in depth and he always asks great questions; the exact same ones i want to ask while listening (as a relaxed audience member. idk if i could do that on the spot like he)...
Very smart dude... I like how he even took the time to explain to explain why to “prion” is pronounced that way... Very soothing voice delivering horrific news...
I am a biochemist from Texas, I used to raise Elk in Wisconsin, Prions are nasty. The change in basic terms, the brain tissue being changed by making a protein shape improperly. This causes healthy proteins to mishappen to a nonfunctional form of the protein but is in terms of protein structure easier to create via protein structure with in regards to chemical science but in the biochemical realm, it makes the protein no longer a viable neurosynapse.
My father was the President of NEBA for about 4 years. When we had our farm we could only test dead animals via brainstem biopsy. If the animal is walking the fence like a zombie you have lost the now destroyed property. This all came from Colorado from CSU losing their test population.
I have a farm in Missouri that had cwd, our neighbor was a trophy farm. Cwd is similar to a forest fire. It can devastate the population, but the population will rebound. Dnr will test your deer for cwd, and usually have testing stations around for hunting season.
I hate to ask but if this deer disease issue is such a threat. Would people be willing to kill all deer to protect ourselves from this horrific disease?
My mom passed away from Alzheimer's in Feb..6 weeks later out of the blue my "healthy" step father died from Cruetzfedlt Jacob disease. Until that week I had never heard of it let alone that it was possible to have this human form. It hits out of the blue up to 10-15 yrs and kills almost immediately. They were deer hunters both of them. They were active and ate healthy. This yesr has changed our lives and to go back home will never have that real meaning again. I turned 43 two days ago and Im absolutely lost. I appreciate your shows Joe. Thanks for your work and the amazing guests you share with us.
That’s sad
i so sorry for your loss and i hope everything works out for you.
@Es1911sumware how did they pass away?
@Es1911sumware That is awful. I have a freezer full of deer meat I am thinking about tossing because I did not get them tested. I also have so consumed the heart of one that was positive so that is worrying me but all I can do is move forward with the best precautions I know. From my understanding it gets in the plants as well, so even vegans are not safe.
I'm sorry Nicole 😭😭 I love you girl I hope you are doing okay mentally and emotionally. Much love and respect.
The biologist has a very soothing voice.
Nessie Andrew like Bob Ross
Facts
I disagree
Indeed!
Would've loved to hear more!
He needs to be a voice on audio books
This guy just covered pretty much everything covered in my biology class's 3-day prion lesson in 20 minutes. Boy, I sure do love paying for college!
Not to mention, 90% of teachers hate their job and make their lessons so fucking boring and impossible to pay attention to.
Ive always said people learn more by talking
@minecraftliberal2009 shoulda done a trade job, im gonna its straight money
Not mention being an engineering major and being forced to take an unnecessary and useless liberal arts class to support their program. That is just plain old, common, thievery.
If it ever comes up in your class small group discussions, this might be an interesting avenue of discussion:
"There is increasing concern about the troubling possibility that blood or blood products, vaccines and other pharmaceutical products could spread the agent of variant CJD (vCJD) worldwide, especially in countries where BSE has not yet been reported. Bovine derived materials involved in the production of vaccines and other pharmaceutical products could represent a way of potential transmission of the disease. Moreover, the possibility that human blood and plasma could be a vehicle for the transmission and spread of the disease have led to a number of donor deferral policies aimed at minimizing the risk of accepting a blood donor who might be incubating the human form of BSE. In addition, blood fractionated products such as albumin are used as stabilizers in the production of vaccines and recombinant pharmaceutical products. There is, therefore, a need to ensure that regulatory authorities with limited resources can have reliable information when making their risk assessment and evaluation of product safety to prevent the transmission of TSE to human via biological and pharmaceutical products."
www.who.int/bloodproducts/tse/en/
Smart people always are so modest. "I know some experts" while refusing to refer to himself as an expert. Seems that stupid people are quick to act like they know everything.
Humility vs. Arrogance
The more you know the more you realize what you don't know. It's not due to smart people having superior character.
"Those who know less, think they know everything. Those who know more, know they know nothing"
DreamBeatsBakery I think Einstein described a similar thing, but on the scale of humanity. As the fire of our knowledge grows larger, the things we know we don’t know increase as the area illuminated, and we also realize as the circumference of this illumination grows, how much we are in the dark.
Smart people think they are dumb. Dumb think they are smart.
CWD is real bad up here in Wisco. Good on Joe for bringing this to the national spotlight.
No its not I hunt around Waco
Are you insinuating that there is a Waco, Wisconsin? Because there isn't... Also if you're not insinuating that there is a Waco, Wisconsin, I don't know why the fuck you felt it necessary to say some shit totally out of left field about an issue I suspect you know nothing about.
It's not totally unknown man. I live in South Carolina and have heard about it for years. Now given I'm a deer hunter so that's probably why. One of the many things I like about Joe is that he's a hunter/outdoorsman.
Well shit now I have to worry about deer killing me?
can you tell me more ?
*The Walking Deer*
Stfu XD goddammit
Oh deer...
PotatoExpress soon it’s gonna be us
PotatoExpress hahahhahah
What about that man that was eating a homeless man comes to fine out he was ex military 🤔
Scary shit, I've been hunting in WI for 20 years and i can remember it starting with just a blip in the middle of the state and now a good 2/3 of the state has cases of CWD. Hell, he didn't even mention that penned deer can infect wild ones just by touching noses through a fence. Scary shit...
So if it spreads to humans, the eskimos will spread it the fastest?
Bmack776 LOL
@@titoxullman I'm glad you got the joke.
Bmack776 underrated cuz not enough ppl will see it lol
@@titoxullman I know, what a waste.
What scares me is how scared that biologist sounds and that is saying something,
May god be with us.
God bless you all
Yeah yeah let's all look to "god"
@@Currentuser Whatever .....your probably behind this Dr. Evil
they're fucking deer. chill tf out. Y'all about to hyperventilate and die over this.
Dude was trying to be hopeful and whether you believe or not said it for everybody, but mock the mans religions for a few likes. ,
amen ram ram god bless you too man from a year ago
Joe "I'm wearing a hat with these guys so our bald heads don't shine in unison" Rogan
😂
LOLOLOL
Blue pill
They could make a laser.
It would be like putting two mirrors facing each other. #baldception
The biologist looks like the badass who survives a zombie apocalypse
Wtf literally looks like a normal guy... and no ones survived a zombie apocalypse so stfu
Jacob Patterson , so mature. Of course a zombie apocalypse hasn’t happened, dumbass. 🤦🏻♂️
Sounds like the new Vegas doctor.
@@TwoHams tru
@@jacobpatterson5332 your probably fun at partys
Joe "correct me if im wrong" Rogan
So nobody is pissed that the video cuts off right before he discusses human infection???
Where is the rest of the video?
The British have done studies of appendices and tonsil tissue in an attempt to determine exactly how extensively vCJD (Mad Cow) may have spread in England. The results were very frightening. However, no one knows how many infected humans will actually develop the disease.
czcams.com/video/E3s6p2UP57Q/video.html
Whatch the full episode dummy
Yeah no doubt
Guy has a good teaching voice
Reminds me a a science teacher in middle school or something
He sounds like the painter Bob Ross! "Happy deer".
That’s why the NPR voice is used to hypnotize you into believing the BS
@@DutchStar what's npr
17:18 - 17:27
I feel like this would be one of the clips at the start of a zombie movie...
Nooooooook dawg don't say shit like that I'm fucking terrified....
Radio Face Walking dead live gaming..sounds mfn awesome
Bruh 💀
Radio Face it already is
Japanese zombie flick
“Train to Hibusa” I think it’s called
@@bigtravis6159 Close. Train to Busan
The terrifying thing about these prions are why they are so resilient. Proteins can be folded in a countless number of ways. Some of these folded states are more thermodynamically stable then others. It's not exactly the same thing, but it's similar to why carbon monoxide is so dangerous as it binds more efficiently to hemoglobin then oxygen does. In fact, part of the reason hemoglobin is so good as a transport molecule is that it's not perfect, it's not entirely stable.. it's what allows that oxygen to be let go of. Disease prions are kind of like that.
The main difference being that these highly stable folded states are so stable that they can't be unfolded by normal processes and they're also so stable they can't actually be used to do anything. This basically makes them just continually build up as the body can't do anything with them and can't break them down to get rid of them. That makes them exceedingly hard to break down and gives them half-lives many times longer than normal. It's also what makes them so resistant to heat as it takes a lot more energy than normal to denature the proteins, and even more than that to destroy them.
That's not the worst part though.. the worst part is that the damn things work like Ice 9 from Cat's Cradle. Every normal prion they come in contact with spontaneously misfolds itself into the new highly stable but otherwise diseased state. It's a terrifying prospect because it means that you just continually produce more of the terrible shit until you go mad and die, leaving behind a body filled with the resilient shit. It's like if Ice-Nine didn't immediately cause you to freeze solid but instead froze you so slowly that you had a few months of the crystals stabbing into your insides and into your brain before the comfort of death finally saves you from the pain.
Very good thesis !
Both educational and terrifying!
10/10
😰
I dont want to leave the house now.
I'd like to get my hands on a bag of that ice nine shit. Joe Rogan said it made his ego disappear when he smoked it.
Joe looks so concerned considering all the elk, deer meat he ate 😭😂
Joe zombie 😆
Lmaoo
@@illumiNOTme326 0
He probably has it already
Laying in bed, low-key having a panic attack right now.. no big deal.
Kirstondo not gonna lie so am I, this whole thing freaky
Fuck. Guess im not eating deer.
I’ve ate elk and deer a bit the past few years, and I live in Colorado you think you’re scared
life is a fragile thing we can we wiped from this planet in the blink of an eye if anything destroy's mankind some strange disease is what my money's on.
@@mr.laconte3207 have you been bitten by deer ticks google lyme disease.
As a venison eater, this scares the shit out of me.
......anybody else recall the beginning of *Train to Busan* ?
Ben
Ok... wow!
Death Dealer ur a fool.
Death Dealer lmao that was a good one, made me laugh.
Like that movie
I wonder if the Simpson's have a episode with zombie deer
I feel like they do
Season 7 episode 9........
Matthew evans no way for real?
Ski Mask The Ugly God haha no I’m just fucking with you, i kinda wish there was though
Train to busan has a zombie deer. Apocalypse Started when someone ate it
It took me 14 mins to realize I was watching 3 bald men talking about deer
That's how you know it's reliable information haha
Lmfaoooo
Lmmfao 14:13 saw this comment
Tfw I didn't even realize
DOE!
For those of you saying that there isn’t any infected deer because you get your deer tested and they show no signs of infection, if you watch the whole video the biologist explains it can take years before any visible symptoms appear and not all results are accurate when look testing for CWD
Bryan Richards would make an excellent university professor! He explained things so clear and concisely with being pretentious or wordy. He's instantly likeable.
"Soilent Green is made from people..."
Remember, those nutrition labels are conteolled by the FDA.
john carville the impossible Burger from Burger King and McDonalds is real life Soylent Green
I prefer soylent yellow
And your spelling is controlled by no one
@@rschmidt93 best comment
Haha those cookies looked good like Christmas cookies
So this proves that it is inherent in the biology that a species should never consume members of their own type....PERIOD.
Hiloha'homa nah this only happens because it’s how it spreads nature doesn’t have morals and doesn’t choose cannibal or non cannibal
Waffles97 nature definitely has no morals but it definitely chooses what ever it wants
Resident evil. Applies to evil rich people mutilating our genetic code GMO
Depends on the species. For mammals, yes, it is usually bad. But for fish and reptiles, it is a good thing and helps the strongest of the young to grow faster.
Don't eat McDonald's #humanmeat
Well now we have the 11th season of the walking dead
More entertaining than all of the other seasons.
I had a patient once with CJD. They seemed like a normal patient with dementia but they were in their late 30s or 40s. However, because i knew that they had CJD it seemed so much more eerie and odd. It was a once in a lifetime patient
That Shit was pretty big in the early 2000s in the UK and Germany. They downplayed it and it was forgotten after some time. The media coverage was pretty big back then.
Not gonna lie...Joe has created a really cool job for himself here. He literally has interesting conversations with (mostly) interesting people from all varieties of life.
Dr. Richards is very impressive. Knowledgable, critical, and a great communicator. Great guest for the show!
Joe talked about this hoe many months ago and now it’s actually getting worse and spreading that’s crazy
Because most topics joe tackles on his podcast are relevant, not like your average news.
Yes BUT its not spread-able to humans yet but they can evolve at anytime or even some1 take 1 and experiment on it and try and spread it to humans, ones things for sure is that they wouldn't say anything imo if they didnt think itl spread to humans at a point
@@rul4n you're here tho
Because he's One of their puppets
This happened in like 1994 when I lived in Wisconsin. They would set up orange markers on corn fields. That was a green light to put down as many as you could and DNR would burn them.
My money says this was intentionally created in a lab in America. They just created GMO mosquitoes that are infused with some biological gene to eradicate themselves.
This is a result of greed. That is the sad thing.
@M S Possibly, especially since it's probably NOT prions causing the TSE infections, but simply a byproduct of the infection,
A lot of evidence points to Spiroplasma, and it has been proven that up to 10% of cases have no prions involved.
"Spiroplasma biofilm formation explains the role of these wall-less bacteria in the pathogenesis of transmissible spongiform encephalopathies (TSEs). Spiroplasma embedded in the biofilm polysaccharide matrix are markedly resistant to physical and chemical treatment, simulating the biologic properties of the TSE agent. Microcolonies of spiroplasma embedded in biofilm bound to clay are the likely mechanism of lateral transmission of scrapie in sheep and chronic wasting disease in deer via soil ingestion. Spiroplasma in biofilm bound to the stainless steel of surgical instruments may also cause iatrogenic transmission of Creutzfeldt-Jakob disease. Sessile spiroplasma in biofilm attach to the surface by curli-like fibrils, a functional amyloid that is important for spiroplasma entering cells. Curli fibers have been shown to interact with host proteins and initiate formation of a potentially toxic amyloid that multiplies by self-assembly. In TSE, this mechanism may explain how spiroplasma trigger the formation of prion amyloid."
academic.oup.com/jnen/article/73/2/104/2917565
Joe: prion
Biologist: prion
Joe: i’ll just call it prion then.
It's right around me Wisconsin and Illinois border. Glad he's bringing this up!
Josh Peterson I’ve been hearing about it being in Arkansas for years now as well.
@@bradygolden5232 same here, im in McHenry county Illinois.
Reppin Walworth county WI here!
I am in Wisconsin as well. I don't know if god is real, but if god was real this is what would happen when sick humans go around bragging about the size of deer they murdered. Deer are one of the most beautiful and peaceful animals.
Now you should be careful with where you get your meat from
Living in Wisconsin I can say that all my friends who hunt say this a really bad problem that could boil over due to the insane amount of deer here in Wisconsin.
You need wolves and Coyotes. Here in CT the deer were out of control and everyone complained. The coyotes came in and have done an excellent job of culling. Now people complain about the coyotes. You cant win
sounds like a career. its already named
The wolves are the meat inspectors of northern Wisconsin.
Chris Kelly lol get fucked I hope we all die for this. It's time for a purge
benjovi55 ... we have a few counties affected here in WV too. The only answer is to offer mass hunting and tagging these deer. The transmitting of this disease will get worse until we take some drastic steps to cull the population.
What kind off antelope decided, it would be a great idea to feed cows to cows?
Fake news cows got fed sheep not cows
@@evanhershey9250 really you think your smarter than bryan?
Bryan literally said that's what they did
Coach Letterman. Beef fed beef is true American
some cheap farmers
We're also fighting this disease here in PA. It has taken a huge toll on the deer herd
I hunt in a CWD area of PA. I've yet to see a deer - alive or dead - with visible symptoms of the disease
I'm in NJ near Easton PA and I'm near a lot of hunting land. Tonight, my brother mentioned this condition after there was a deer right in front of our house look at the outdoor cat. It wasn't scared at all and we were talking on the porch 8-12ft away. I spoke up a bit and it still didn't move. I do remember seeing deer doing this last year too!
Joe "corect me if im wrong *cough* " rogan
He said that as I was reading this and I chuckled.😂
Joe "I hope I sound smart saying this" Rogen
Lol I read this right when he said it
This is why I listen to Joe Rogan podcasts
This is one of those things that is technically "possible" to fix, but would require so much perfect planning, fencing, culling, and control over every deer it is essentially impossible
extinction says hi.
fencing is the problem
when CWD passes to people, they will say-"this is a new disease, we did not know about it and did not assume that this would happen, it is impossible!" But in fact, they could have prevented it 5 years ago.
CJD
This is why you listen to actual experts on CWD and not Ted Nugent.. Ted Nugent doesn't know shit from shinola anyways.
Test Ted Nugent for mad deer disease! ...yep, he's positive! 😰
@@budshakebob3431 There are plenty of professional hunters and some countries are even using their armies for this. So insane people like Nugent aren't really the only option.
Samurai Jack Ted Nuggent is an idiot. You don't have to be a liberal vegan that's never killed a deer to understand Ted is crazy. Stop acting like you know someone you have never met and making assumptions if you don't want to look like a fool.
Haha "shit from Shine-ola". I haven't heard that one, since the 80s. Well played.
Hehehehehehehehehe... you are so clever... and macho... Fucking inbred idiot!
Basically - Cannibalism = Bad.
Feriin except for pigs well and other animals. It only applies to some
Couple of insects, lotsa fish, young chickens, dogs, (etc.)
dolofonos - Go mess yur hat
Mmkay
Bascially minus Cannibalism??
Someone let me know when it's safe for me to eat deer meat again. Thanks.
What about the predators and scavengers eating these animals?
Very valid question..
Oof
Brent animals have a very good instinct about what isn’t safe to eat healthy
Coyotes and wolfs...
Even if they cant get it, they shit prions out over their territory.
So cannibalism started the zombie apocalypse?!
Steve Flow don’t ruin season 10 of TWD!
Ironic
@@madjack821 yea
The wendigo curse.
so Umbrella will come to pass through the merging of these corporations feeding cattle to cattle...none of which will stop...long after this thing jumps species to humans...
That biologist should be in a movie..
As a Norwegian I got equally excited every time he said «Noooorrrway», tingley stuff man
They keep bringing up possible human transition, but I’m more interested in how or if it can affect predators that hunt these deer, or possibly other herbivores that come in contact with infected waste or even a water supply.
*puts down controller
*IVE BEEN PREPARING FOR THIS MY ENTIRE LIFE*
this made me laugh
it is time
Don’t forget to knife the first 3 rounds
Its the deer purge let it begin someone get the deer with the dieseise and make a person eat it so we can finaly have the fun
People like you can't last a week with no electricity
Gotta thank Joe for bringing this critically important topic to his worldwide platform. CWD has been on the DNR'S radar for at least 20 years. There are new cases of discovered every year but we've been able to for the most part keep it out of the northern herd here in WI. It's still something that is in the back of all of our minds here who are deer hunters.
We had numerous white tail die from this the last two years in Nebraska. It's weird how the infected deer act as well. Lethargic, not afraid of people and act almost as if they are just walking around without a rhyme or reason. Scary stuff makes us hunters think about how our meat may be infected around the area.
"When Ted Nugent was on the podcast he downplayed the consequences and effects of something called CWD"
You can always count on Ted Nugent for his extraordinary insights.....
Dav he’s got more experience in the woods than really anyone he’s had on the pod
@@BryanTheHunter He has more experience in the wooooods! You got me bud....
@@joblo1978 Sure thing bud.
Next time don't lead with this trash "Right. Because all scientists agree, all scientists are never wrong, biased, or greedy, and science never refines itself, And, unless you’re a scientist, you know nothing. Not all info on CWD from scientists corroborates."
Dam dude you a sheep willing to follow what ever some with a lab coat will tell you. Yeah that right don’t think and put in your own research and experiments just follow the trend.
@@BryanTheHunter Molecular biologist research chemist Ted is not. CWD is like mad cow disease on steroids and would cause non familial SCJD in humans. Dont listen to Ted, hes cabal and his job is to downplay CWD so a bunch of second amendment supporters get killed by this disease. Ted's a fucking idiot, not a scientist.
Joe " oh no I need to buy my meat from a store now" Rogan
When the apocalypse happens, us gamers will finally rise up in society
Yeah right, you pussies can't survive without delivery food and video games. Your not killing shit cause all your guns are downloaded. You guys are the first to to die and have your resources taken.
@@TheMontyR Jeez, someone piss in your cheerios?
We will rise up but sit back down right away because our cardio isn't the best
@@GamePath Don't worry, by the time of the apocalypse, Trumps wall will be built and you won't have to worry about this dude
Manuel Rodriguez it’s a fucking joke, Manuel, chill out
The biologist is exactly what I expect, clear, intelligent and very direct.
Es1911sumware you must of not heard or understand what he said. Did you hear the whole cast ?
Es1911sumware It appears that you are well educated and have a personal experience with Jacobs desease, that’s great. My point was that the biologist clearly explained what CWD is and capable of doing. I am coming to you from an academia point of view. And no, I will eat the deer, always have.
Es1911sumware clearly you are biased because of personal experience, I get it. But the I formation the biologist put out about the actual desease is accurate.
Es1911sumware how are you able to determine that they are lobbying of 1 hr of pod cast? Seems like you have them beat on Knowledge, do you have your own podcast I can listen to?
@@Essumwarewhy are you convinced it isnt happening ? I dont trust the government, but how much profit would these guys be making off of this lmfao seems like a super random thing to have a conspiracy over.
This is the kind of person I wish taught me science as young person! Lived what he's talking a about and articulate,fascinating.
Well its all over the news today😂
Hello Guy doesn’t this pop on the news every year? Also now I’m paranoid over deer meet I ate a few months ago...I live in sask
@@no_sleep_yx3 it doesnt pop in the news often. But it seems serious now.
Hello Guy 😂
UncleRucus I honestly don’t really give a shit 😂 I just thought his response was funny cause it was something a 12 year old would put. This disease has been around for a long time and in my area it’s been here for a long time. So it doesn’t phase me tbh
@@no_sleep_yx3 at least you get to be the honor of being the first ever zombie
My mother died of Creutzfekdt-Jacob Disease, sudden onset, in 2009. It's a horrific way to watch someone waste away.
TSE, the prion's in the brain fold, which is sudden and fatal.
sandy smith you can read my mothers obituary. Mary Lee McGill of Kingston, TN.
After this, I don't give a rat's ass what you believe.
+Sandy smith - I BELIEVE HER SO SHUT UP.
Predabot Predabot thank you.
:(
As I posted above, I have a friend that died of Creutzfekdt-Jacob Disease last year and I have a client who also has a friend that recently died of this as well. What are the odds of it only killing 300 people in the US a year. Im thinking its much more prevalent. We are not being told because no one really knows how is is contracted. Because it may take 40 years to kill a human I feel there may be no urgency to find a cure. One thing for sure, I will never eat deer after hearing this podcast.
Reindeer herds range from Lapland in Norway, Sweden, Finland, and through Northern Siberia. The loss of those herds would be catastrophic to the herders who depend on them for food, shelter, and clothing.
All I will say is this. I worked with a PhD researcher specialized in CWD and worked exclusively in CWD research. He contracted CJD, the human version of CWD. Quite the coincidence as he had no other exposure.
Isn't CJD a 1 in 1 million chance?
@@howardman3926 no its not. rates are steadily increasing. could be due to better ascertainment/ diagnosis. and there are case clusters in different parts of the world. public health lies when it says that its a consistent 1-2 in a million disease.
How about we address the Chronic Dear Headlight Disease ?! My front bumper needs answers
lompockid this is clever
lompockid - 😂😅🤗🤣
Can't stop laughing 😂😂
Ill buy all the road kill venison you got
lompockid we need to bring deer mental health awareness to the public as suicide rates are high. Only logical explanation as to why there are so many deers jumping infront of cars
I have constantly wasted disease.
Kaos One me too. I've been told there is no cure yet
@@chupacabraracing181 only cure I know of is "yes I'll have another."
Kaos One that's what I just told myself. 1 more joint before bed=nice dreams
So basically we could potentially see an actual apocalypse, or at least an outbreak
i would like to see nugent and this guy on the same podcast
his head is so shiny
Lovia Kinzo Ikr. Brighter than my future 😂
Not as shiny as the barrel of this 10 mm once I get bitten
I need more lemon pledge
im a bald biologist from the institute of bald sciences in madagascar, im not bald myself, what that means is that i study bald people for a living, their habitats, everything about them, check this out: it has been proven that when in inminent danger, bald people sometimes use the reflection of the sun on their heads to blind their enemies and gain a situational advantage also called gaining a bald initiative
also flies never land on their heads, ever, and judging their age is at least 70% harder than other groups of people
more public money should go towards the study of bald people, they are trully an amazing bunch
Joe your hunting and wildlife guests are usually the most interesting. The cyote guy was incredible
Joe "I think I'm infected" Rogan.
We still feed the rendered cow parts to the other cows. And don't think you get off the hook with 'free range' either. Cow feed without rendered cow in it is more expensive so almost no one uses it. This could explain the growing number of dementia and Alzheimer's we are seeing. Like everyone grandparents have that shit, sadly including my own. Its Horrific. If we are going through this to save 4$ a bag on cow feed its not worth it.
i thought renedered cow in feed was banned. it is in Canada and UK.
I could listen to Bryan all day. Smart, field qualified, humble and intelligent.
Kuru is a terrifying disease.
sandy smith TOO LATE!!!!!!!!
Scary shit. Sadly never eating deer again after hearing this.
Just dont eat deer brain.
@@daniellion5291 doesn't it spread out through most of their tissue??
I work as a disease investigator and this scares the shyt out of me. Your'e telling me an infected deer that's incubating can test negative but still transmit infection for 3 to 6 months? Man thats worse than syphilis lmao
Read Deadly Feasts, it explains everything he's talking about. Fore tribe in Palau New Guinea were cannibals, which is where first cases of Kuru occurred. Kuru means "laughing disease", which is what my momma did; she had a few days of uncontrollable laughing. This disease is horrific.
Azzury Street you're wrong. The women of the Fore tribe were starved by their husbands, so they had to resort to the eating meats of the other females who died. The vital organs were choice, fatty meats, and unfortunately the brain is where Kuru (CJD) resides.
You think you're being funny, but you're talking out your ass. I sure hope that you or a loved one never dies from this horrific disease.
Hillary Clinton also has Kuru, laughing fits and a gaping hole in her tongue combined with all her connections to human traffickers and cannibals enthusiasts/pedophiles
That’s so sad. Sorry for ur loss. If u don’t mind me asking how did ur mother contract it?
Ramon Almeida we donated her brain to the Prion Center in Cleveland Ohio, which was THE only was to 100% confirm CJD, and which type. Hers was Sudden Onset, which had been laying dormant for years. Thank God it was not familial or from eating wild game, or mad cow disease.
Tammie Renz hopefully that tribe is extinct they serve no purpose on this earth
I used to hunt antelope in Alberta 20 years ago. The wildlife conservation officers would check recent kills for visual signs of wasting disease in these populations also. It was a relatively new phenomenon 5-10 years prior to the first observed cases. At that time it was suspected to be due to a lack of natural predation and a reduction in wilderness areas for food sources. However, indigenous populations in southern Alberta used to tell stories of warriors that developed a "madness" from eating to many Buffalo skulls; which was a prized food source due it being a very rich source of fat and protein. So, BSE may have been present in the environment long before cattle were brought to North America. My understanding of the pryon is that it can survive in range of 100's to 1000's of years.
I just imagine an A10 warthog shredding through a herd of reindeer then I remembered they weren't in America lol
Nor are our a10s
Joe “correct me if I’m wrong” Rogan
Joe " you have no eye deer " Rogan
lee green Whos *joes*?
Ramen noodle shawty 4LO oops my bad player 😂
What do you call a deer with no eyes
Thanks for the great presentation. In 2002 CWD broke out less than a mile from my family’s tree farm in South-West Wisconsin. We have been working with both state and federal agencies regarding this problem ever since. While there is no doubt it is a problem, it is not the disaster it was first claimed to be. The epidemiological models that predicted a collapse of deer populations not only in Wisconsin, but nationwide were a bit exaggerated to say the least. As we approach 20 years experience with this disease we are seeing the emergence of animals that are more tolerant of the ravages of this disease. This was to be expected. The differential survival of more resistant animals propagated their genes in greater numbers at the expense of the most susceptible. This has resulted in a drift toward a population of more disease tolerant animals. This is not to be confused with resistance or immunity. The animals still contract the disease and die from its effects but at increasingly older ages. Considering the average male whitetail deer has a natural life span of 6-7 years in the wild, even a modest toleration of the disease mitigates its effect on reproduction rates fairly quickly. Wyoming has seen a similar trend over the years as well.
Still the captive animal farms are the primary risk perpetuation this disease. Montana took the steps early on to outlaw the farming of game animals and it worked fairly well, yet we are now seeing the first cases moving up from Wyoming.
Sounds like mold exposure. They eat from piles of food sitting outside...
Странно Хрипы morons think every disease is caused bt fongus because their brains are too simple
I just clicked on this and if joe does over 25% of the speaking I’m gonna be mad
Issue sounds deer to his heart...
You......... son of a........
That was good
ros1tony I see what you did there lol
No
@Christian Slater I second that
As a bio major... this was interesting AF!
Even as a High School student this was interesting.
Same here!
@Christian Slater or maybe having learned some useful critical thinking skills in the field they found it interesting and attributed that interest to said learned skills?
"As a blah blah blah, I find this blah blah blah"
See this template everywhere
@Christian Slater Your jealousy is showing.
The end is near, gamers get ready, normal people seek help from gamers and let the survival begin
Lol.... yes. Gamers leave your mother's basements and teach the world the wealth of knowledge you've gained from pre-programmed outcomes in controlled situations
Gamers rise up
Well I heard an interesting tidbit out here. I heard that bone meal was brought here from Britain just before they discovered their mad cow problem, and gave it to cattle here!
Love the diverse and informative topics...I've watched a bunch of your shows but I subscribed because of this one...This is better public service then most news stations. Taking the time to cover the subject so that people can make informed decisions on how this matters to them. LOVE IT!
The only answer is to ban commercial deer farming and game farms.
My family has a whitetail deer farm in western iowa where there are no documented cases. My grandfather has had every deer that dies tested since 2000 and not one has had the disease but I'm starting to worry with the spread lol
i fell into the deepest powernap 2 mins into the guests' soothing Bob Ross-esque voice
This sounds so like what is happening on Dairy farms in NZ. Whole herds are being slaughtered.
You say pree on, I say pry on, why don't we call the whole thing off?
i'm always surprised how much Joe is able to follow intellectual discussions in depth and he always asks great questions; the exact same ones i want to ask while listening (as a relaxed audience member. idk if i could do that on the spot like he)...
It's also affecting coyotes, raccoons and other animals like cougars. Reminds me of the show "The Last Man on Earth"
Anyone tryna link when the time comes?
WorldRecordEggo dm me
On Instagram g_money_317
💯😂
Im in Atlanta cuh. Hit me up. Hope you can shoot and tell the truth
Rogue Video Productions I just uploaded a video of the zombie deer
Very smart dude... I like how he even took the time to explain to explain why to “prion” is pronounced that way... Very soothing voice delivering horrific news...
And remember, the govt has a plan to deal with a zombie event...
Adam Perry what is it
I am a biochemist from Texas, I used to raise Elk in Wisconsin, Prions are nasty. The change in basic terms, the brain tissue being changed by making a protein shape improperly. This causes healthy proteins to mishappen to a nonfunctional form of the protein but is in terms of protein structure easier to create via protein structure with in regards to chemical science but in the biochemical realm, it makes the protein no longer a viable neurosynapse.
My father was the President of NEBA for about 4 years. When we had our farm we could only test dead animals via brainstem biopsy. If the animal is walking the fence like a zombie you have lost the now destroyed property. This all came from Colorado from CSU losing their test population.
I love to get baked and watch these videos 😂
My mother was a mad cow, my whole life.
I have a farm in Missouri that had cwd, our neighbor was a trophy farm. Cwd is similar to a forest fire. It can devastate the population, but the population will rebound. Dnr will test your deer for cwd, and usually have testing stations around for hunting season.
I hate to ask but if this deer disease issue is such a threat. Would people be willing to kill all deer to protect ourselves from this horrific disease?