The Future of Cancer Research | Freethink
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- čas přidán 16. 09. 2018
- Intel employee Bryce Olson was diagnosed with stage 4 prostate cancer. When the standard of care didn't work, Bryce turned to genomic sequencing which allowed his doctors to identify specific genetic drivers of his disease and identify specific treatments and clinical trials that were a fit for his specific cancer. This precision medicine approach helped send his cancer into remission for several years.
Now that his cancer has returned, Bryce is working with the Broad Institute and other leaders in the field of advanced cancer research to use artificial intelligence powered by Intel technology to discover new, innovative solutions that can help him and millions of others like him around the world.
This video was produced in partnership with Intel.
Learn more about the work Intel is doing to power the future of healthcare intelligence at intel.com/healthcare
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You can now order a "Sequence Me" t-shirt, with proceeds donated to the Children's Cancer Association! intelamericasstore.com/ProductDetail.aspx?did=28390&pid=257394&logoid=0
This channel really is underrated. It’s very informative and I’m learning about things that I would’ve never heard about if it wasn’t for this channel’s existence. Thank you, Freethink team! ^^
Shala Nguyen I agree
Thanks very much, Shala and Kuro! We appreciate all of you for watching and sharing our videos!
Boggles me how this channel doesn’t have more attention it’s very short but packed with info, I’ve never not been bored with any of these videos
Hope you mean "never been bored," but thanks for watching either way :)
Cause many people are not interested in useful and meaningful information to enrich themselves
Bryce is still alive and continuing his work 👍
I'm exactly who this video is talking about. Stage IV, already spread to my brain. Chemo, radiation, surgeries, immunotherapy; none of it working. Now my insurance company won't approve PET scans to determine if a treatment worked or not, because its better for them if I'd just die already. So who exactly am I "demanding" genetic sequencing from? All I have are my doctors, and they're run by insurance rules. I appreciate you posting this video, but it's definitely giving a false sense of hope. For those of us who don't work for Intel, and live in the American healthcare system, what do we do? If you're going to tell me to do something, follow through and tell me what to do. I'm serious. I'll demand anything. Tell me who I could possibly demand it from.
John, Bryce here. First off i'm really sorry to read this. Heartbreaking honestly. Tell me where you live and where you're getting care. In the meantime, this is what I would do. I'd call my oncologist and tell him/her that I want molecular profiling / genomic sequencing of my cancer. I'd say I'm stage IV and I've failed standard of care and dammit I need this to hopefully open new doors into a clinical trial or off-label use of a drug that's more of a genetic match for me. If he/she shrugs shoulders and says "we don't do that here" then hang up the phone and go to nearest academic cancer center near you and demand the same thing. You'll need to submit to a needle biopsy to get a lesion that is relatively easy to access and not cause risk to your health (i.e. brain isn't a good location obviously). Liquid biopsies (this is a blood test where docs look for circulating tumor DNA) is also an option, but I just think in 2018 the physical sample is the best to really get something actionable. But the liquid biopsy is sure a much easier non-invasive way to go and if you have a lot of circulating tumor DNA these tests should pick it up. I say this because I don't...I really need to docs to look at physical specimen for me. Now let's talk payment and reimbursement. If you're on medicare, coverage for tests like Foundation Medicine's Foundation One (your doc would send sample to them) or MSKK's IMPACT test for example got approved this year. If you're getting health insurance through commercial provider, then your doc needs to request online notification/prior authorization to grease the skids and avoid hiccups with the payer. You could still get declined. If that happens request the doc to submit it again, and again. If that fails, demand to talk to the head of pathology and ask him/her how you can get this done. Tell him/her you want to be on a study that is on-going. Many cancer centers have large genomic research projects and very much so want patients to participate. This data is valuable. Data is the new oil. Genomic data is very strategic for them to acquire, some have large grants and will try to get your insurance to cover but if that doesn't work they'll figure out something. Many of these have internal policies where if research grade sequencing finds something actionable, they will communicate that to the oncologist and use that to help plan therapy. You should demand "did you find anything actionable?" afterwards if you get in one of these studies. If all else fails lets talk and brainstorm because I have a lot of contacts in the industry. Ok? 5 years from now this will be routine practice to sequence patients, but tech and science are advancing at exponential rates and the medical industry that cares for patients hasn't caught up yet.
Thanks very much for sharing your knowledge, Bryce. Hope this helps, John, and we are all pulling for you.
John I am so sorry that you have to go through this. You're braver than anyone I have ever known. I will pray every night so that you may recover.
I wonder if john is still alive. Seems unlikely :(
I hope you found the right treatment. :-(
Freethink never disappoints. No bullshit. Pure information. What I love is how they engage in a way that you feel concerned and connected.
Thanks very much, we appreciate it!
This is the type of channel that I expect to have millions of subscribers, but there aren’t enough! Keep up the work, Freethink
i got this ad when i was about to watch dog memes
and now i feel like i've missed out on life
thank you so much for this
HI Bryce, God bless you.
My dad was diagnosed with cancer in 2017 and at that time we're losing hope since we know that cancer doesn't have a cure. Thankfully his cancer was controlled but he's still continually going through check-ups to make sure it doesn't grow again. This gives us another option if it recurs. Thank you for sharing this information as this is very helpful. Please continue making videos like this and I love your channel!
If Bryce can see this message, i'll be thrilled. I've been studying the biochemistry and pathophysiology of cancer and other diseases for a while now, and i'm on my way to medical school to pursue functional/holistic/integrative medicine in a family medicine clinic. More specificially, I've been researching epigenetics and nutragenomics, and the tenets of functional medicine, which are nutrition, fitness, sleeping habits, stress management, toxicity, gut microbiome, emotional/mental health, and several other factors. I was also able to help my dad reverse his prostate cancer using a variety of protocols, which is actually what jump started my research interest in these fields of study. It turns out that even if someone is genetically predisposed to a disease such as cancer, epigenetics and nutragenomics shows that the genes can either be turned on or kept off, and that actually determines the degree to which it can develop into cancer. Some of the things that can turn these genes on include smoking, alcohol, a poor diet, environmental toxicity, stress, and several others. This research with genomic sequencing is all well and good, but the aforementioned factors are what cancer patients must address in order to get to the root cause of their disease, and it's very similar with other diseases. Pharmaceutical approaches to most diseases don't work because they often don't address the root cause, and also - in Bryce's case, resistance can occur. Chemo and radiation, as well as several other drugs also usually don't kill the cancer stem cells, as they are often resistant. This is a huge issue! As a result, the cancer usually recurs, and usually at a more aggressive rate. One thing that I would recommend Bryce to do is to go on a raw food plant based diet (as close to 100% raw as possible), with lots of juicing/smoothies. The reason is that plant based foods/herbs/spices contain a myriad of compounds that obliterate cancer cells in a variety of ways. They include: interrupting the signal cascade pathway for proliferation, angiogenesis, and promoting apoptosis. There are several other mechanisms, this is just the tip of the iceberg. One of my favorite of such compounds is Curcumin, the active compound in turmeric, and is one of the most potent of all of these compounds. It has been shown to kill cancer cells via all of these mechanisms! To note, Piperine, the compound in black pepper as well as some kind of fatty acid is critical for bioavailability. I could go on about so many other compounds, and other tips in general, but this comment would be extremely long, lol. Thetruthaboutcancer.com, chrisbeatcancer.com, cancertutor.com, and several others are good websites to research various ways to tackle cancer. A lot of it is nutrition based, which only makes sense. After all, most pharmaceutical drugs are derived from nature. We have only scratched the surface discovering the medicinal values of plants, herbs, spices, fruits, vegetables, nuts, seeds, legumes, etc. Bryce, if you could contact me, that would be great. I would love to share various resources to help you! Keep up the good work, and God bless, you will be in my prayers! I'm glad I saw this video :)
Have you done any research on cancers being a fungi? Aren't all of the most effective cancer fighting drugs just strong anti fungals? I listened to a Dr. Several years ago who said he and his team were ostracized from the medical community in Rome because they were curing cancer with $.10 worth of baking soda instead of a million dollars worth of pharmaceuticals. His research had shown him that cancer (fungus) cannot live in an alkaline environment which the body is supposed to be but, if your body is acidic then cancer can grow freely.
I agree with you. I myself has survived a very aggressive form of a breast cancer by switching diet and life style without chemo. As a pharmacist and an Asian medicine doctor, I didn't agree on medical approaches of cancer treatment at all. Over 7 years passed since I got diagnosed and I'm cancer free. Epigenetics would be more scientific way to understand all the critical factors to prevent /cure diseases but the core is so well known and easy - water, nutrition, sleep, sunshine, exercise, stress management, breathing, and warmth. The key is how much of them. For example, current agricultural produce can't satisfy our daily nutritional needs and a cancer patient should go through intensive juicing (over 2 liters of raw vegi juice) to supply enough nutrition to the body. This remedy doesn't motivate any industries but organic groceries so that patients are blinded about this remedy. Sad...
Nice , had a relationship with two girls who get breast cancer and the other one breast cancer and leukemia too. The funny thing is when they had to go back home after losing their jobs an spending all their money they got better after being forced to subsist on good homegrown food. With barely any meat (they could barely afford meat). I've since suffered as well but after following what I sawim now stronger and even look younger. I'm forty but look and feel like I'm in my twenties. I'm doing some research myself and found some commonalities with some food.
@@renviluan2842 That's awesome! Since that comment I found a few other doctors to check out, Dr. Kristi Funk (holistic breast cancer specialist), Dr. Joel Fuhrman (family doc, wrote 11 books), Dr. Brooke Goldner (reversed her own Lupus), Dr. Saray Stancic (Reversed her own MS). All of them are Whole Food Plant Based (WFPB), which the evidence is now even more clear, helps prevent and reverse virtually every chronic disease/condition! Check them out when you can, their videos on here, websites, books, etc.! God bless :)
I've shared this to a lot of friends of mine..This channel deserves this and even more . Glad to be a subscriber of a channel which is gonna have a million subscribers very soon !!
Thanks so much for subscribing and especially sharing! That's how we'll get to a million, fingers crossed :).
Hey chitu..
@@shashvatpatel3694 hey 💐.. contact me at hangouts..-chituboruah494@gmail.com
Ok
I saw this video as an ad and this is amazing.
Glad you liked it!
You see there is a side of me thinking what if he didn't accomplish things in time and that's why I'm in tears.
I love your commercials. All the doctors. Of the world are absolutely. Wonderful.
Who else is here after Technoblades death from cancer? Cancer has taken so many lives of some wonderful people, i hope we can all see a day where we treat all cancer types successfully. RIP Techno ❤️
I don't understand why anyone would dislike this video
Awesome video and channel! Who edits or produces your videos?
Very impormative and can save most of cancer deaths
Great video and very informative. Sad that many cancer patients may not even know about advanced genomic sequencing, and their doctors don't mention it either.
Wow 10/10 this is TV level production and wholesome! Very good video
The intel plug is blatant but they are making it happen I suppose lol
This is amazing and I believe there are ways!
My school chromebooks have Intel in them.
I am from fiji how can i get this done.
This is amazing!
Hope he gets better!!
Just think how much further we would be had they used AMD :p
Imagine disliking a center research video
What happened to Bryce? Also, could you please link to the research that the Broad Institute does on using ML to sort through large genomic data sets.
Sadly, Bryce passed away in July of 2023.
Precision medicine, the right drug at the right time
This is awesome but how much did it cost cause last I remember this kind of stuff costed a TON of money
Why isnt this everywhere? Only 600 likes? This is the stuff that people should be liking not useless crap.
wait was this an AD?
The earth is already at the point where its impossible to safe. But i love when people gives us more time to live just by doing something they love. Just so you 7 procent of the world drink water is already contaminated and its been inceasing alot the past decades soooo. Example: in Denmark we just dug 300 new waterholes and they are all contaminated all those waterholes should hold atleast decades before they where useless. Usa is drying up and getting cold. Bangladesh is floding and china is contaminated korea is just ehm.... and the golf streams are getting hotter and hotter in some years its gonna be a disaster.
This is not the case for Radiotherapy. Every treatment is planned individually for each patient, each tumor location, type and probability of spread.
The 27 people that disliked this are down bad
97%
I hope we develop Artificial Intelligence more to combat this disease. A human brain has limitations and Artificial Intelligence might be the answer. Technology might save people's lives. I heard 3D printing is now being researched for organ replacement too. If I were a rich man, I would fund this research ASAP.
"I really shouldn't be here today" okay *skips*
in all seriousness, pretty amazing video.
Interesting
Why does this have dislikes?
Doesn't the DNA in a human make up to about 200 PetaByte per gram? So a person weighing 100 kg who has 300 g of DNA will have 60 000 PB of storage...
I only want to know if what you say is according to the size of the tumor sample or you are not go that genomics
who tf disliked this
Yeah I doubt _precision medicine_ is an option for very many in our current healthcare system...unless you’re wealthy.
Cost is always an important question when it comes to health care.
The good news is that as technologies become more mainstream, they get cheaper - as the video indicates, the cost of sequencing genomes has fallen from billions of dollars to about a thousand. At that point, it is certainly possible to make widely available as a diagnostic tool - and it could save a lot of money, especially when it comes to dealing with cancers which cost health care systems, insurers and people exorbitant sums of money. In the case of Bryce, he unsuccessfully tried chemotherapy, surgery, and radiation - all expensive procedures - before the sequencing lead him to a medication. If this approach is broadened, it could save tremendous amounts of money while improving outcomes (and avoiding the physical pain of the other approaches).
The actual cost to customers may depend on the country or insurer, of course, and there is much improvement to be made in those areas. There's a lot of new approaches being tried as well, and hopefully in the future better treatment will be available for all.
Very true, thanks for taking the time to expand on that. It complements your video well.
No problem, thanks for watching and have a great day!
A channel that respects its viewers, my god so rare
Yup...survival of the richest my friend. 🙁
many people are donating their CPUs to cancer research though BOINC, nowerdays the cryptocurrency Gridcoin and GBYTE motivates them additionally to participate in research. Give them a chance, the computing power grows every day!
Okay...... will my medical insurance cover this?🤔
No, becuz it’s experimental
Just be sure to put your dollar into research and not the collection plate and the cure will come MUCH sooner. I guarantee it!
Up next:Fighting AI with cancer, the story of microsofts tai bot, the hitler loving robot
Cancer research:
As we know that all types of cancer cells turn from healthy cells to cancer cells due to 24.14 % of damege on cells in the age system or the cell's age system . making the cell allowed to have 900 years old or almost immortal when the system of the cell's age is changed more than 12 .3 %,, accidental chemicals gets produced from the cell's nucleus forming a state of weakness in the cell forcing an Environmental phase that suits cancer . the infected cancer cells functions differently there is 13 ways that cancer cells function under.. all of the ways use the nucleolus to produce ammoniac substances affecting the cell's cytopasm reducing affections on how the immunity system works making it 74.2% weaker and in a state of tightness . wich makes cancer illness that is 46% active 98.3% active and over brain phases that the brain goes trough; the brain gets fooled that it should reduce blood pressure 32.4% bellow normal blood pressure level to heal cancer . there could be more than 64 method to heal it one of my methods is injecting the left shoulder's axillary artery with 80 ml of chnc3 it would raise the blood pressure up to 51.3% higher: making the cells in a state of refreshments and an amount of white blood cells will produce iron and vitamin B it will enforce the cancer cells to change the structural print of the cell. the chnc3 won't just travel trough 76% blood system it will also reach the cancer cells and it will make the cell die or change into a diffrent type of cell as a healthy one, and it can also either change the age of the cell from above normal to normal enough meaning that the damaged age system either brakes to 3 seconds or 64 minutes or 80 hours or 3 days or 5 years ;,or the cell will freez meaning that 1 of these statistics is either the time when cancer cells end or freeze or heal and keep a very small percent of cancer illness small chemical compounds and else so as we can see the cause of a normal cell turns into a cancer cell:. It is caused because the age system in the cell have gone out of it's supoesed natrual limt wich is why cancer is caused anywhere there's only two types of cancer cells that gets healed differently ... instead of chnc3 there should be a different healing method for them if you know what kind of cancer cells are those two last cells I mentioned I believe that if they should appear one would be in the eye and the other is in the right kidney .so they would be healed with heat for the kidney one and the eye one should be healed with ion salt grade 23, so please share and add more info in the comments or ask questions about cancer and I'll acknowledge more .
And thank you for supporting cancer research 😴.
Tons of vitamin c.
Bro who dislikes this
Who the hell disliked this video :///
Who tf disliked this
Sequence me doc
Potato’s
Anything for us fat people, we can save people with aggressive cancers ( and very happy and hopefully about that) but nothing for us fat people
dhaval1489 idk man you can try workout... Or fat removal surgery...
@@riyadh9936 surgery is not such a simple answer as of workout it's works but I just keep getting fatter no matter what eventually fatter then even when I started
Do more cardio work out. Instead of lifting weights, cardio workout makes your heart burn fat faster as compared to lifting weights which builds up your muscle.
Also look what you are eating. More protein and less sugary foods
Contact me, I have a ton of resources to help you!