Ester vs Amide Local Anesthetics || How they differ?

Amide local anesthetics play better therapeutic profile over ester local anesthetics in many aspects but still they can produce more toxic reactions than ester derivatives. In this video, the main differences between these two categories were discussed in detail.
#localanesthetics
#lidocaine
#benzocaine
0:00 Introduction
0:08 Groups in Local anesthetics
0:49 Types of local anesthetics
1:14 Ester and Amide LA
2:38 Differences
2:57 Acid dissociation constant (pka)
6:52 Onset of action
9:47 Chemical stability
13:07 4. Hypersensitivity
13:46 Drug interactions
15:08 Tissue toxicity
16:29 Ester LA

[@sultannz]

As a surgeon looking for quick refresher of info. I found your video illustration one of the best videos . Right to the basic points which are very important and use of animation. Well done

[@egpat]

Glad you liked it ! Thanks for watching.

[@liljackass6998]

Great video! Very in depth, and you explained concepts i knew before but forgot, good job!

[@egpat]

Glad you enjoyed it! Thanks for watching.

[@Iraqiacom]

Thank you very much for this excellent and wonderful explanation. I wish you success

[@brijeshprajapati6613]

Tq so much sir 🌹🌹🙏🙏 you are great sir
One day will come that you have millions subscribers according your work content and understanding style great sir 🙏🙏🙏 no has word to explain you sir 👍🙏

[@samget2475]

We can differentiate them by how they are spelt, amides have 2 i’s while esters have single i

[@Lastletter688]

I can never thank you enough Sir, you are a hero

[@tusharkapsikar5302]

Thank you!!! Excellent with clear, detailed explanation 👏👏💖

[@rupeshpawar4618]

Thanks u sir for this effort from u and made concept clear and understandable it will help to everyone

[@manojramanujam8571]

Very clear understanding sir..💐
Definitely it will get more popular..

[@egpat]

Thank you.

[@joanaborges9450]

Thank you so much for this video, very helpful. It really helped me during my college exam season.

[@egpat]

Glad it helped you. Thanks for watching.

[@kabrakabra]

Very well explained 👍🙏🏻.

[@shaikhmohdjunaid9528]

excellent video👍👍👍👍👍

[@30nareshkaraka5]

Tnq very much sir for giving valuable information sir . Finally your explanation so good sir

[@egpat]

Thanks for your feed back. Keep watching for more interesting videos.

[@gregorytumweti5411]

Thanks so much

[@prajwalareddy2603]

Thank u so much Sir

[@chiragsengupta8728]

Excellently described 👌🏻 Loved it😍

[@egpat]

Glad you liked it. Thank you

[@manasipawar1999]

You are the best teacher...I love your videos..It helps me lotttttttt😊

[@sunitadevi-kb2ve]

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[@jakub379]

Thank you for your video! Sir just one thing, for onset of action, it is not pKa , but concentration what matters, ester have faster onset than amids, beacuse they are less toxic , they can be given in higher concentrations, 3% chlorprocaineis the fastest, even it has highest pKa

[@pimpinelishaw95w]

amazing thank you so much

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[@Medicoworld893]

Thank you sir

[@egpat]

Welcome. Thanks for watching.

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Nice class.thank you Sir

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[@shalinikesharwani1694]

🙏more valuable

[@khondokarakilahmed1981]

Thank u so much

[@egpat]

Most welcome. Keep watching.

[@chaima5027]

Meilleure cours des al

[@kusumagompa2381]

Tq u sir

[@egpat]

Welcome, thanks for watching

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saved my life

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Class apart your a wizard

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THIS DUDE HAS VERY THICK SOUTH INDIAN ACCENTS EVEN NON SOUTHINDIAN INDIANS HAVE TROUBLE FULLY UNDERSTANDING

[@elmaspower2356]

Sir why are you keep saying anastics again and again?? Isn't it anesthetics?? I don't want to sound mean, just couldn't help myself from asking ..

[@sunitadevi-kb2ve]

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Thank u so much sir

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Thanks sir

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