Peripheral T cell Tolerance - Clonal Deletion and Anergy (FL-Immuno/78)

This video lecture discusses mechanisms of peripheral tolerance.
Clonal Deletion
Anergy
Immune Deviation
Immune Privilege
Immunosuppressive Cytokines
Regulatory T cells (Treg) cells

[@shafiakhan5023]

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[@hinawajid1575]

Perfect explanation ever!

[@samuelh1766]

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[@hussainthaer2942]

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[@FrankLectures]

Glad to know that these videos are such a help to you all. 😊 Thank you for your valuable feedback.

[@nadasaeed5422]

thank you so much . great , simple and conclusive

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the most interesting and easily understood explanation, keep forward presenter.

[@WanC9]

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Thanks for saving my life.

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[@yogayantra]

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[@FrankLectures]

Thank you for your feedback.

[@sahirajaafar1470]

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[@vincentgogh2389]

Really well explained.

[@vaishnaviraghupate1611]

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[@FrankLectures]

Thank you for appreciating these videos.

[@nawfianazeer7292]

Best explanation ❤️

[@martinasunflower4949]

Great explanation ! Thank you:)

[@FrankLectures]

Thank you for your feedback.

[@somayehboshagh5514]

This video is more than perfect
What if I did know this channel when I was a student

[@usmansaleem6135]

Very good explanation,
Kindly explain peripheral tolerance attained by CD8 cells specifically in separate video

[@omegaphillip6863]

Nice explanation easy to follow

[@Ham-os2wk]

Excellent man

[@RaginiHzb]

Saved me

[@user-fp5fd9pf7p]

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[@ajaysinha7467]

great explanation ....now I feel I can atleast write something in my exam....💞

[@FrankLectures]

Thanks

[@joyusang8884]

I now understand better ❤️

[@muskanmittal5415]

Appreciated 💕💕💕 I understood it very well.😊

[@FrankLectures]

Thanks

[@kirtityagi308]

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[@drranafatima7875]

That was useful ..

[@AmritaPBB]

well explained

[@tanusreehalder3557]

such great videos...thank you :)

[@FrankLectures]

Thank you for appreciating these videos.

[@tanusreehalder3557]

Please make videos on post transcription and translation modifications..

[@noraahmed6135]

Thank you.. Please I need a lecture about adhesion moleculed

[@aliayad8444]

Nice

[@adamprabowo4556]

All was great! But one thing in minus, the voice shouldnt made by google translate or robotic :) Thaaaanks a lot

[@shwetapatel-bq4st]

All of ur videos are sooooo helpful... I request u to please please upload videos on different cell signalling and signal transduction pathways.... Please....

[@FrankLectures]

Cancer biology lecture series will be followed by Cell signalling lecture series. But it'll take time. Thanks.

[@shwetapatel-bq4st]

@@FrankLectures that's fine.. Thank u soo much...

[@Talal2430]

really good video

[@FrankLectures]

Thanks

[@user-hy8hp8xs3r]

Helpful vedio
Thanks..

[@FrankLectures]

Thanks

[@elahehaddadi1641]

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[@FrankLectures]

Thanks

[@vikasraghuvanshi8551]

Nice.....

[@FrankLectures]

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[@wakylaugh]

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[@easy_medlife2793]

Thanks from Indian occupied Kashmir

[@subinbyclema]

Immune deviation previlege immunosuppressive cytokines TGF-B IL-10 blocks APCs, Treg

[@Dhanapraveen851]

How many feels that teaches like najeeb

[@subinbyclema]

Peripheral tolerance Anergy Immune privilege prevent T cell activation control Immune responses maturation of DCS T cell activation

[@subinbyclema]

Co stimulatory molecule PRR, B7 (DCs)peptide-1. MHC complex- TCR lymph node- naive T cell(2. CD28) 3. cytokines auto reactive T cells self Ag source of self antigen no co-stimulatory molecule apoptosis apoptosis programmed cell death 1. peripheral clonal deletion 2. anergy(remain inactivated) prevent of auto reactive T cell activation.

[@subinbyclema]

Central T cell Tolerance peripheral tolerance mechanism peripheral clonal deletion Anergy Treg prevent T cell activation control immune response maturation of DC danger signals (cytokines, complement, microbial products)

[@mudassariqbal6874]

Aslam u alaikum Sir
Sir i need your help
Please guide me
I have read photorespiration from my book here there is a line that
(In most plants photorespiration reduces the amount of carbon fixed into carbohydrates by 25%)
The question is here that how 25% ???
How exect 25%???
Please help me
I have also searched from google but no satisfaction!!!!!

[@FrankLectures]

Waalaykumu assalam!
Answer to your question is little bit complicated. But let me try to explain.
In normal Calvin cycle all the carbons which enter the cycle as CO2 are fixed in the form of carbohydrates. So, amount of carbon fixed in Calvin cycle is 100%.
But if you have studied photorespiration in detail, you should know that when O2 is added to RuBP, two phosphoglcolate molecules are required to produce two glycine molecules. In a series of reaction one molecule of 3-phosphoglycerate (3PG) is produced which is fixed by Calvin cycle.
Net reaction is...
2 Phosphoglycolate (4C) + O2 -----> 3PG (3C) + CO2
Here, out of 4 carbons, only 3 are fixed in photorepiration. If you take out percentage of carbon fixed, that is, 3/4*100= 75%. So, 75% carbon is fixed. Remaining 25% is not fixed. It is released in the form of CO2.
So, "in most plants photorespiration reduces the amount of carbon fixed into carbohydrates by 25%".
You can study this concept in the book.....
" LIFE the science of biology, Sadava"
I hope it is helpful to you.
Thanks

[@mudassariqbal6874]

Frank Lectures
Thank you sir
Now my all concepts are clear
You are great sir
Love you❤❤❤

[@FrankLectures]

Glad to know this.

[@a2_damar_2a93]

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[@tammamzouihed3371]

If only the voices weren't google translate it would've been better , I was annoyed by them and couldn't concentrate