My lecturer had taught us this over the course of 3 hours - you gave me exactly the same information in small mini-clips. Please continue to do what you do, we appreciate you :)
Does anyone know what the exact fate of an immature B cell in anergy is as it leaves into the periphery? Why doesn't that autoreactive B cell activate itself (T-cell independent B cell activation) and start to proliferate?
T-cell independent B cell activation requires 2 signals 1. Clustering of BCR on multivalent Ag 2. Recognition of danger signals The 2nd signal is absent in case of self Ag and thus leading to Anergy of the B cell
perfect videos but needs much more improvements I think it's very important to enhance the voice over and it will be much greater hope you the best in shaa' allah ^^
No interaction weak cross linking B cell development in the bone marrow Central B cell tolerance 1. receptor editing 2. anergy 3.clonal deletion VJC receptor editing light chain loci immunoglobuline gene non self reactive migrates to periphery
Can you please send me the Power Point that you have used in this VIDEO in my E-Mail ID? Also please mention the reference book that you have used for the figures......It's really a wonderful video and your power of explanation is simply amazing - Dr Raktim Mukherjee (Head of the Department, Shree PM Patel Institute of PG Studies and Research in Science, Sardar Patel University, Anand, Gujarat, India)
My lecturer had taught us this over the course of 3 hours - you gave me exactly the same information in small mini-clips. Please continue to do what you do, we appreciate you :)
You just made me pass my module. Thankyou. Everything is perfect.
Thanks
Very informative video✌
Every thing is perfect 👍,Thank you soo much 😘❤...
Thank you ❤️
Good job, keep it up.
Thank you for your feedback.
Helpful
Vert nice & unique
Thanks
what causes the failure of central tolerance?
Source of self antigens in the bone marrow blood plasma molecule strength BCR-Ag multivalent effective cross-linking BCR glycolipids Ag
Does anyone know what the exact fate of an immature B cell in anergy is as it leaves into the periphery? Why doesn't that autoreactive B cell activate itself (T-cell independent B cell activation) and start to proliferate?
T-cell independent B cell activation requires 2 signals
1. Clustering of BCR on multivalent Ag
2. Recognition of danger signals
The 2nd signal is absent in case of self Ag and thus leading to Anergy of the B cell
perfect videos but needs much more improvements
I think it's very important to enhance the voice over and it will be much greater
hope you the best in shaa' allah ^^
and I offer any help that can help you become better and better
Thank you for your feedback and suggestions. We will work on them. Thank you.
narration/video pace could be sped up a bit. great info, tho. i listen to these at 2x speed
Thank you for your feedback.
Clonal deletion unresponsive anergy apoptosis
lecture begins from 2:04
No interaction weak cross linking B cell development in the bone marrow Central B cell tolerance 1. receptor editing 2. anergy 3.clonal deletion VJC receptor editing light chain loci immunoglobuline gene non self reactive migrates to periphery
Can you please send me the Power Point that you have used in this VIDEO in my E-Mail ID? Also please mention the reference book that you have used for the figures......It's really a wonderful video and your power of explanation is simply amazing - Dr Raktim Mukherjee (Head of the Department, Shree PM Patel Institute of PG Studies and Research in Science, Sardar Patel University, Anand, Gujarat, India)
It's a good video but the audio is bad
Бир кунда нечта ичиш керак катталар
The content is very rich in info , but the voice is so distracting :(
Thank you for your feedback
Video is great 👍🏻but audio are of poor quality!!!👎🏻