Protein Structure (Part 3 of 4) - Secondary Structure - Beta Pleated Sheets
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- čas přidán 3. 10. 2013
- UPDATED Beta Pleated Sheets Video: • Protein Structure (Par...
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In this video, I explain the details of beta pleated sheets.
Beta pleated sheets are the other commonly known component of secondary protein structures. Basically, beta pleated sheets are polypeptide chains that have “creases” or “pleats” in them (shown in the video), each “pleat” being an alpha carbon of an amino acid in the polypeptide. These polypeptide chains run adjacent to each other, either in a parallel or anti-parallel fashion. The R groups on each polypeptide chains alternate in their presence above or below the sheet that is the polypeptide chain. Beta pleated sheets, like alpha helices, are held together by hydrogen bonds between the backbone. However, unlike alphas helices, the hydrogen bonds that hold beta pleated sheets together are perpendicular to the direction of the sheets.
In the video I draw beta pleated sheets running parallel to each other. Parallel refers to the polarity of each sheet in terms of N-terminus (amino terminus) and C-terminus (carboxy terminus). If both beta pleated sheets are running NC in the same direction, they are said to be parallel. If they run NC in opposite directions, they are said to be anti-parallel.
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This was extremely helpful! Many times the fact that B pleated sheets can exist within one polypeptide chain or multiple polypeptide chains is overlooked.
This series really helped clarify the topic of protein structures for me. Superb job. Thanks!
That was extremly helpful ! You just clarified in 13 minutes what the professor couldnt explain in two hours ><
Thanks a bunch :D
Getting sick and missing a class or two in Biochem is extremely over whelming when trying to catch up, because of your video series it has made the "self-teaching" less stressful. Thank you so much!
Maggie Demaine Haha! Awesome! I'm happy that's the case. You're very welcome!
Thank you so much! Your videos really help! Really great initiatives!
Straight to the point. Great explanation of the basics - and keep up this messy drawings!
amazing explanation Sir ! the last part really cleared my confusion a lot
Awesome awesome awesome explanation. You taught me soooo much more than both my MCAT prep book and my Biochem lecture lol, so thank you!
i just watched 3 of your videos they're great ...keep em coming
this video was so so so helpful! You should make a video about interactions like hydrophobic vs VDW in the protein folding!!
Thank you very much , this was helpful .and it changed my whole idea , that biochemistry is a hard subject .
Thankyou
it is really helpful, you made it so easy as piece of cake.
Reema Panjwani Yup! That is, indeed, commonly overlooked. I'm glad the video was helpful.
just wow to way you explain , very great ,shukran:D
Helped a ton! Thanks so much.
Aakriti Ramayani Sweet! You're welcome so much!
Thanks! Helps a lot :D Keep it up!!
2022- and saving my life before my biochemistry exam ❤️
I really appreciate your work man...Keep posting...thanks a lot...
Rakesh Yadav Thanks, dude! Will do.
You pretty much got me prepared for summer class before it even started cheers
Lol. Sweet. Rock that class, dude.
Wow, thank you sooooooooo much! You really helped to clarify some concepts.
Jo S You're welcome sooooooooooo much, dude!
youre amazing!! Thank you soo much!!! :DD
Thank you! I was sooo confused with alpha helix and beta sheets... Cannot visualise what beta sheets are
awesome video, this really helped me in understanding the idea of B-sheets in my biochem undergraduate class. id buy you a coffee if i knew you
blueguyrighthere1 Sweet! Thanks! I'd like some free coffee. Haha!
Thank u sir ❤️🙏🏾
very nice
thanks a lot.
shukran ya mahfoud
hakam jameel Ahlan, dude!
Do you have any videos on phy and pshy angles? I can't really understand them :(.
nice video
Hi, can someone explain to me the difference between phi/psi peptide characters? I'm so confused on this.
I thought the secondary structure does have more than one polypeptide chain. When there are H bonds between separate POLYPEPTIDes, ISN'T that the quaternary structure?
nice bro! thank you!
Rory Button Thanks! Sure thing!
I guess my problem in understanding these is more of a general perspective.
If given a molecule and asked what the structure of the protein was would a species with two different amino acid chains still be considered secondary as long as the chains are parallel to one another?
Just in case you haven't gotten your answer yet and you still need it, it's because beta sheets involve Hydrogen bonds between the peptide bonds (this is ONLY at the level of a secondary structure). When the subunits become linked at the level of the side-chains, that's when you consider the molecule to be quaternary.
doesn't it become a Quaternary structure if there are multiple polypeptide chains being linked to each other by the hydrogen bond. I thought it was segments within a single polypeptide chain that form the secondary structure
Watch out I'm coming to u mr exam
I dont understand the Turns , Loops ,multiple turns , hairpins ...>
moof u boss
3:42 and 3:53 bless you.
Hahaha! Thank you!
U ROCK dude ! Awesome ! Who r u ? Gosh ur 10000 times bettr than my moronic professor.....😝
Hems J Lol. I am Moof, First of His Name, Breaker of Confusion, Bringer of Knowledge, Savior of Students, and Protector of the Realm. Hahaha! Thanks for the kind words, dude!
SAMEEEEEEEE and they get paid so well :S