Astaxanthin for Skin Anti-Aging: Does it work? [Study 285 Analysis]

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  • čas přidán 8. 06. 2024
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    0:00 - Introduction
    0:52 - Topics Covered
    2:05 - Mechanisms of Action
    15:57 - Meta-Analysis Bias Assessment
    21:27- Astaxanthin on Skin Moisture [and How to Read the Data]
    26:54 - Astaxanthin on Skin Elasticity
    28:02 - Astaxanthin on Skin Wrinkles
    29:45 - Mid-Point Conclusion/Take Aways
    *******CRITIQUES, RULES, AND NOTES*******
    Critiques of my work are welcome! Please be aware of the following notes & rules before submitting critique:
    The information provided in this study analysis is limited to the subject and outcomes detailed in the study analyzed [For example: “Consuming sugar (subject) raises insulin (outcome).”] and is not meant to be an all-encompassing education on every health outcome of the subject (unless otherwise stated). I welcome all respectful critique of the study as I may have missed a key detail that you may catch; if that is the case, I will make an ‘Amendment’ to the video and credit you (thank you for making science knowledge better!). Also be aware that I receive hundreds of CZcams comments per day, so the only way your critique can be considered is if you follow the steps outlined below. Finally, CZcams auto-deletes links, so I do not see most comments with links attached.
    RULES:
    If your comment is rude, you will be banned without warning.
    If your comment is not about the studies/topics at hand (i.e. extending to other outcomes not discussed) or offers critique with no scientific basis, your comment will be ignored.
    If you can follow these rules, I will try to address your critique and if there is merit, I will add an AMENDMENT to the content in question and pin it so everyone can see it.
    Please use the following link to submit your critique: bit.ly/PhysionicCritique
    Disclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
    #astaxanthin #antiaging #skincareproducts

Komentáře • 253

  • @Physionic
    @Physionic  Před 24 dny +13

    No amendments, currently.

    • @nicolatesla5786
      @nicolatesla5786 Před 23 dny

      Nick you might want to mention how sugar is bad for skin. Fructose impact on skin cells ? Have you seen the annete larkins videos? Raw vegan diet showed her aging by 45%

    • @tamer6893
      @tamer6893 Před 17 dny

      @@nicolatesla5786 45% less aging but 100% less pleasure in your life, not worth it bro. And I'm sure you can reach the same results with smart nutrient compounds and exercising 3 to 5 times a week without removing sugar in your life.

  • @StackedCrooked
    @StackedCrooked Před 24 dny +163

    This is totally anecdotic and worthless as evidence, but I recently stopped needing reading glasses after taking Astaxanthin for about 3 months. I started Astaxhanthin in the hopes it would protect my skin and stop further deterioration of my eye sight. Then I recently realized that I (unconsciously) stopped using reading glasses about 3 weeks ago. So it seems to have not only prevented further deterioration, but actually reversed some of the damage. Didn't expect that at all. (I hope it lasts.)

    • @mballer
      @mballer Před 24 dny +15

      How much are you taking? What brand?
      How strong were your reading glasses?

    • @edils0
      @edils0 Před 24 dny +8

      Great to hear, and definitely not worthless as evidence.

    • @intoxicatingGold
      @intoxicatingGold Před 24 dny +6

      Can you give more details?

    • @StackedCrooked
      @StackedCrooked Před 24 dny

      @@mballer I was on the weakest strength they had, I think +1.0 or +1.5. I'm taking Astaxanthin 8 mg AstaPure.

    • @thomcarr7021
      @thomcarr7021 Před 24 dny +4

      This is nonsense. It's just speculation at best.

  • @paulhindle3961
    @paulhindle3961 Před 24 dny +62

    The dermatologist who was surveying the basal cell carcinomas on my neck a few years ago asked what I did for a living, when I told her I was a pilot she said that she saw quite a few flight crew for the skin cancer issues. Since then I have been taking 12mg astaxanthin daily. A molecule that evolved for one purpose only, to fight solar radiation, sounded like a great thing to have in your body when exposed to the higher levels of solar radiation at 35,000'. Apparently NASA has done experiments with astaxanthin and similar for the same reason.

    • @Physionic
      @Physionic  Před 24 dny +15

      Sun screen?

    • @Mario-forall
      @Mario-forall Před 24 dny +21

      ​@@Physionicpilots are exposed to cosmic rays though. Not sure how effective sunscreen is against X and Gamma rays.

    • @paulhindle3961
      @paulhindle3961 Před 24 dny

      www.nasa.gov/wp-content/uploads/2018/12/introduction_508.pdf?emrc=fd7451

    • @paulhindle3961
      @paulhindle3961 Před 24 dny

      @@Mario-forall www.nasa.gov/wp-content/uploads/2018/12/introduction_508.pdf?emrc=fd7451

    • @laveshanmunsami794
      @laveshanmunsami794 Před 24 dny +3

      ​@@Physionicphysics vs biochemistry

  • @shay5025
    @shay5025 Před 24 dny +35

    Hoping you'll take a look at photobiomodulation! Otherwise known as red light therapy, it seems to be hugely multinodal with little to no negative side effects. Theoretically works through increased ATP and ROS production.

    • @onetime7408
      @onetime7408 Před 24 dny +3

      I would he very interested in this too.

    • @user-ti9zc1xv2b
      @user-ti9zc1xv2b Před 23 dny +3

      Blue light therapy quite literally saved my life when the harshest skin disease medication could not

    • @chrismacdonald4570
      @chrismacdonald4570 Před 5 dny

      It's not theoretical. Red light photons effect complex 4 improving the function of Cytovhrome oxidase and increasing the creation of ATP within the cell. Other wavelengths of light ( violet and green) act on the other 3 electron transport chain complexes.
      Erchonia is a brand that holds most of the patents and their lasers ( low level) have received FDA clearance for Pain and Inflammation relief. They were trying to get FDA clearance for Autism because they had the data but I am not sure if it has yet been granted.
      Erchonia has a YT channel but are not the only manufacturers of laser products.
      I use red light products and red laser products
      Both work, but laser is MUCH more beneficial,but more expensive
      Hope this helps.

  • @minefacex
    @minefacex Před 24 dny +11

    It is such a nice thing that you release some of these videos for free :)
    Thanks as always for the professional content!

  • @misskatiamay
    @misskatiamay Před 22 dny +7

    Am a huge fan! Your presentations are amongst the very best out there. Thank you!

  • @jayalanlife5926
    @jayalanlife5926 Před 24 dny +26

    Love your work Nic, keep ploughing on with your excellent analysis

  • @sarahsaller9033
    @sarahsaller9033 Před 24 dny +17

    Great presentation - you sound like a professor, and the information is excellent! Thanks for a great video! :)

  • @lairheron9489
    @lairheron9489 Před 24 dny +6

    Love your deep dives man. You're really providing a service to the world and peoples health.
    Would love to see a video on dysautonomia and POTS from post viral infections and what exactly it is.
    You have great skin by the way.

  • @mickkali
    @mickkali Před 24 dny +4

    Thank you !!!! You are an exceptional teacher ❤

  • @EHoser1
    @EHoser1 Před 24 dny +18

    I started taking astaxanthin a couple of years ago because I read somewhere that it might help reduce blood glucose. It didn't. But my heart arrhythmia stopped immediately.

  • @marinafoglietti9351
    @marinafoglietti9351 Před 21 dnem +11

    I am 76 aged woman. I'll try astaxantin. I have been taking Collagen NMN vit d3 vit C glynac but without any improuvement at all, nor for skin neither for memory. I am Italian and here and everything is so expensive.
    I do exercises and walking every day.
    I'll let you know for astaxantin.😊
    I eat well, no smoke, no alcool, no sugar.

    • @AriCat777
      @AriCat777 Před 21 dnem +3

      Look into senolytics and how to take them, like Fisetin, Apigenin, Luteolin, Curcumin, Quercetin and Milk Thistle. Also make sure you get Vitamin K2 with your D3. And the cheap Vitamin C comes with many problems.

    • @AriCat777
      @AriCat777 Před 21 dnem +1

      Hot and cold therapy increase mitochondria.

    • @theancientsancients1769
      @theancientsancients1769 Před 19 dny +2

      ​@@AriCat777NMN must be from a reputable brand with TMG . But I found Cacao and Alpha Lipoic Acid and Omega 3 fish and Longvida Tumeric the most powerful stuff that noticed the difference with along with Astaxanthin! Milk Thistle too improving the liver

    • @zamolxezamolxe8131
      @zamolxezamolxe8131 Před 19 dny

      Did u take the right dosage?

    • @srezzy1326
      @srezzy1326 Před 14 hodinami

      The other thing I learned about taking collagen supplements is that you need more glycine to absorb and utilize it. And the amount in collagen isn’t enough for its absorption when you get older. Several people had said they added it and it made a world of difference. I’m trying it but it takes time to see results from the inside out.

  • @itaygev1377
    @itaygev1377 Před 24 dny +33

    i think it's important to mention with all your videos about skin supplements that overall nutrition, resistance training, limit sun exposure and sleep are the main and most important when it comes to keeping your skin young :)

    • @nattypatty3667
      @nattypatty3667 Před 24 dny

      You need sun exposure for vitamin D. As long as you're not burning your skin, the sun won't really age your skin at all. Melanin literally blocks UV damage. You think humans always lived inside? Our bodies adapted to the sun... that's why ppl that live closer to the equator have darker skin, and they have very low rates of skin cancer.

  • @nickmatthaes5344
    @nickmatthaes5344 Před 24 dny +22

    You should make a video covering the evidence for and against astaxanthin for preventing cognitive issues like Alzheimer's and Parkinsons. As someone whose father, grandmother, and aunt had Alzheimer's, I care less about how I'm going to look as I age.

    • @hitmusicworldwide
      @hitmusicworldwide Před 23 dny +3

      It goes together. Many times people who are descending into dementia start to neglect their outward appearance as they shut down to the outside world so a bit of vanity a bit of care for our appearance to maintain it in a healthy state is important nonetheless. There is recent research about cannabis extracts helping with Alzheimer's.

    • @anareginacoronado1147
      @anareginacoronado1147 Před 19 dny

      So you’re saying it can help against Alzheimer’s or it can make it worse?

    • @theancientsancients1769
      @theancientsancients1769 Před 19 dny

      ​@@anareginacoronado1147Astaxanthin reduced blurred vision for me

    • @pretendingToBe
      @pretendingToBe Před 18 dny +2

      My mom has started showing signs of cognitive decline and i'm in the process of researching things that can be done to prevent it.
      To my dismay, I found that lots of literature suggest not a lot can be done but i found a ray of hope. I highly reccommend the book *The End of Alzheimer's: The First Program to Prevent and Reverse Cognitive Decline* by Dale Bredesen md.
      He goes into detail what his reasearch shows is a whole plethora of processes(genetics, sleep quality, adequate blood values of vitamins and minerals, exposure to toxins, hormone imbalance, blood glucose levels etc) that can tip the scale toward or against cognitive decline and Alzheimers. He developed a whole protocol reCODE to guard against it and even reverse it.

  • @kristinvc349
    @kristinvc349 Před 24 dny +9

    Biggest effect i have noticed in my n of one experience with astaxanthin is that i haven't gotten a sunburn since starting to take it about 2 years ago - even on my winter holiday from Canada to Panama. Great stuff.

    • @pierrejeanes
      @pierrejeanes Před 23 dny

      yeah yeah last week I tried to get tamed 😎without luck 🤞, like 5 hours in the sun and barely tanned, it seems like it's first mission is protect the skin 😅

    • @soulmagic752
      @soulmagic752 Před 3 dny

      Same!

  • @skinpa
    @skinpa Před 24 dny +6

    @Physionic Your skin looks flawless. Would love a video on what your skincare routine is, what you use topically, and what you take :)

  • @garyr1934
    @garyr1934 Před 11 dny

    Thank you for this
    It came into my feed
    at the perfect time
    I have been taking it
    But not regularly
    I’ll start

  • @gdiup9241
    @gdiup9241 Před 22 dny +1

    Thank you Nico for sharing your studies analyses(sp) i am a fan girl!

  • @MrLemonbaby
    @MrLemonbaby Před 19 dny +1

    Nick, I just watched a discussion with three doctors analyzing the data on Glynac it was so convoluted that I couldn't make heads or tails of it. Contrasting that with your review, broad, complete and understandable I felt compelled to say thanks for consistent superior performance.
    Yes, I know this is a different topic but I thought posting here you were more likely see it.

  • @aaro96live
    @aaro96live Před 21 dnem

    Dang, well done! I sometimes feel that I lack the ability to critique studies to this degree and as a med student it's invaluable, so thank you for your hard work!

  • @sambo7734
    @sambo7734 Před 24 dny

    that was fantastic :)

  • @ImaJunkyoBell
    @ImaJunkyoBell Před 24 dny +3

    Great work as always! Nic with all the videos you create about lipids and their associated biomarkers have you ever considered a deep dive into peroxisomes, PPAR, factors that up or down-regulate their lipid metabolism activity, the resulting effects on trigs / LDL, and any available agonists? (fibrates vs any similar but natural compounds) I'm trying to do the research and it's breaking my brain. 🤔

    • @Physionic
      @Physionic  Před 24 dny +4

      Fascinating topic. I’ve never done a deep dive into perixisomes, but my thesis is on peroxisomes and metabolism, so… look out for a lengthy video in a while (need to finish my thesis, coming soon…)

    • @ericwarmath1091
      @ericwarmath1091 Před 24 dny +2

      ​@@PhysionicI have enjoyed Dr Barrie Tans work on tocotrienols and lipids. Not sure if you know this work but could be influential on your thought processes.

  • @kindke
    @kindke Před 20 dny +1

    Hello @Physionic , sorry for off topic but im trying to find an older video of yours where you share with us the discovery that a certain hormone works by changing the threshold firing potential of cells/nerves, you mention at the start of said video to stick around until the end for this interesting bit

  • @badex3301
    @badex3301 Před 24 dny +20

    I took astaxanthin for a month straight and my skin was incredible and My eye sight felt better too. But as a gym head, i felt it was stifling my muscle growth. All this makes sense when you look at the fact that its a potent antioxidant. Clears reactive oxidative stress on your skin but also cancels out the “good” inflammation needed for muscles to grow.

    • @Physionic
      @Physionic  Před 24 dny +8

      I like your thinking, B.

    • @sunnygirl9691
      @sunnygirl9691 Před 24 dny +2

      What product were you taking? Have you considered a lower dose or an on/off dosing?

    • @m.b.593
      @m.b.593 Před 24 dny +3

      Could the time you take it matter? Like work out in the morning and take it at night. 🙏🏻

    • @jackbuaer3828
      @jackbuaer3828 Před 24 dny

      I have not seen one study whereby Astaxanthin impeded muscle performance .Your position may (or may not) be nocebo based. That is, based on a belief that Astaxanthin dampens inflammation caused by exercise and therefore impedes the benefits of exercise. Astaxanthin does not appear to interfere with processes that increase muscle growth / strength in the study below.
      Waldman HS, Bryant AR, Parten AL, Grozier CD, McAllister MJ. Astaxanthin Supplementation Does Not Affect Markers of Muscle Damage or Inflammation After an Exercise-Induced Muscle Damage Protocol in Resistance-Trained Males. J Strength Cond Res. 2023
      In this mouse study, antioxidant cocktail including astaxanthin increased muscle growth. (I know we're not mice, but maybe this provides hints as to what may happen in humans)
      "Combined intake of astaxanthin, β-carotene, and resveratrol accelerated muscle hypertrophy."
      Kawamura A, Aoi W, Abe R, Kobayashi Y, Wada S, Kuwahata M, Higashi A. Combined intake of astaxanthin, β-carotene, and resveratrol elevates protein synthesis during muscle hypertrophy in mice. Nutrition. 2020.
      In this study in the elderly, astaxanthin / antioxidant cocktail appeared to improve muscle strength in elderly individuals that exercise.
      " In a randomized, double-blind, placebo-controlled study, Liu et al (46) examined a test formulation consisting of astaxanthin (12 mg), tocotrienol (10 mg) and zinc (6 mg) on building strength, endurance and mobility in exercise training among the elderly. A total of 42 elderly subjects (aged 65-85 years) were recruited, fed with test formulation or placebo for 4 months and trained with increasing intervals of incline walking for three months (three times weekly for 40-60 min). In this study, muscle strength was presented as maximal voluntary contraction (MVC) in an ankle dorsiflexion exercise, and the tibialis anterior muscle size was measured as cross-sectional area (CSA) using magnetic resonance imaging. The authors identified a greater endurance in a 6-min walk upon exercise training in both experimental groups.* The subjects administered astaxanthin formulation had higher MVC and CSA, indicating improved muscle strength and size as compared to the placebo-treated exercised subjects"*
      Wong SK, Ima-Nirwana S, Chin KY. Effects of astaxanthin on the protection of muscle health (Review). Exp Ther Med. 2020
      It would be good to have more studies on younger exercise trained people to get a more definitive answer.

    • @badex3301
      @badex3301 Před 24 dny

      @@m.b.593 maybe! but it think because it’s so potent and has got a considerable long half life, it’s not exactly great if you workout a lot. I’m going to try to experiment with a 3-4 day interval use.

  • @MrNeomatrix99
    @MrNeomatrix99 Před 24 dny +8

    So should it be added to our daily routine?

  • @HelloWorld-bc9fe
    @HelloWorld-bc9fe Před 22 dny +1

    If we join physionic insiders do you reveal what supplements, if any, you personally take? I’m curious but can’t seem to find it in your channel

  • @brendasmith9076
    @brendasmith9076 Před 23 dny +4

    What amount of astaxanthin was used in the studie?.
    Thanks for you work in doing these!

  • @jonasg5889
    @jonasg5889 Před 24 dny +1

    Great video, as usual. Have you looked into Lipofuscin? I think that is an overlooked substance in the role of aging and it's harmful effects in the body. Would be interesting to get your take on it.

  • @jimmcintyre1966
    @jimmcintyre1966 Před 24 dny +17

    Don't know if you saw my comment on your last video, but as one of the millions of people diagnosed with osteoporosis, I think a review of the evidence surrounding supplements and physical therapies for the condition would be very valuable. Things like optimal vitamin D levels, magnesium, vitamin K, protein needs, collagen peptides and trace minerals and physical therapies such as impact exercises like heel drops, weight training, weighted vest wearing and other osteogenic loading exercises. And anything else you can find. Plus preventative measures those at risk of developing the condition could take. Would also love to hear your take on commonly prescribed drugs and whether they prevent rebuilding bone.

    • @jpintero6330
      @jpintero6330 Před 24 dny +1

      We know all of that in combination will absolutely prevent bone loss if you start before the loss begins. We just need a way for people to do all of them before they care about the topic. Also, Biosil.

    • @francoisemullen417
      @francoisemullen417 Před 22 dny

      Check The Dr Doug show. He does that.

  • @plants_and_wellness1574
    @plants_and_wellness1574 Před 24 dny +2

    Will you add this supplement to your regimen after this study?

  • @kamalolama4124
    @kamalolama4124 Před 23 dny +2

    As usual your videos are very interesting and useful.
    However I didn't get information on the recommended dosage.
    Specially that if further studies conclude that for skin care, topical is better, then Astaxanthin shoukd also be taken orally for cellular health.

  • @soulmagic752
    @soulmagic752 Před 3 dny +1

    I am 51 and have been taking astaxanthin internally and i mix it with all my skin care oils for face and body. for 15 yrs.. I have zero age spots and the sun spot/frecals have faded soo much .. I rarely get sun burned either as long as its not all day in the sun... I highly recommend it, it is also great for workout recovery.. a lot of athletes use it for sore muscles and some say it improves strength and endurance.. I wont stop taking it!

    • @molina.cyn777
      @molina.cyn777 Před 2 dny

      Can you kindly share the brand? :)😮❤

    • @soulmagic752
      @soulmagic752 Před dnem

      @@molina.cyn777 No problem. I first learned about astaxanthin from Dr Mercola yrs ago. He has since been censored and taken down from CZcams for helping so many people with their health.. I always try to find his product with his name right on the front in a brown glass bottle. And i never orfer form amazon, too many issues with fake products... get from your local health food store or order directly from companies. If i cant find dr mercola brand at my store i get solgar.

  • @myself3d
    @myself3d Před 24 dny +9

    Just love astaxanthin, been taking it since many years. One problem with it is the quality , or doubtful quality found on the general market and often the unknown origin. Also astaxanthin is often said to be not much bioavailable in many studies about it. It needs to be dissolved in lipids first or encapsulated with oil. The extraction process could also be important. The only brand I trust now is valasta because of its special composition attached with a glucose molecule, as nature made it before extraction and it's also made in US as opposed from many products from China. Astaxanthin is one of the few, if not the only, antioxidant that cannot become itself a pro-oxidant, so it's totally safe (flamingos, salmons and shrimps could tell you because their reddish color come from consuming astaxanthin in their food chain!). Also astaxanthin is said to be 'the protector of the cells' because it protects their membranes from free radicals and that's why many users don't get sunburns when exposed to the sun, contrary of how their skin reacted before taking astaxanthin.

  • @onealjones9039
    @onealjones9039 Před 23 dny +2

    It works, but can lower diastolic blood pressure.. did mine unfortunately, under 60, went back up when i stopped taking astaxanthin. When taking astaxanthin daily, my skin tag feel off, (no joke) my skin appeared younger less wrinkles, also my hair was fuller, my eyesight seemed better and i felt great in general.. it's amazing stuff... but alas, the bp issue is real for some folks. 😢

  • @ericalewis9047
    @ericalewis9047 Před 24 dny +3

    I take this and one night i woke up checked my phone and could see it! Never hear that before I took it so it cant be like a placebo.

  • @Schu2505
    @Schu2505 Před 12 dny +1

    As an antioxidant, how does it compare to alpha lipoic acid?

  • @contagiousintelligence5007

    Do you have a video about methylene blue?

  • @baileystruss7319
    @baileystruss7319 Před 24 dny

    Would it also benefit other connective tissue?

  • @Maevelikeschampagne
    @Maevelikeschampagne Před 24 dny +1

    I guess I'm finally going to have to become an insider...😆 On a more serious note, I'm wondering if this would provide any relief for ecxema.

  • @farhat5325
    @farhat5325 Před 23 dny

    Anything interesting on the framingham study ?

  • @MrMalzers
    @MrMalzers Před 24 dny +6

    Can you do a video on a potential protocol for people that have lost a substantial amount of weight and are dealing with loose skin?

    • @dcjohnson2208
      @dcjohnson2208 Před 24 dny +8

      I’m an old retired scientist (octogenarian). In recent years I went from 320 lbs to 195 lbs with loose skin. Daily fasting for 18-24 hours (with excellent nutrition high protein and high excellent fat like EVOO , nuts,seeds, avocados) melts away the excess skin, tightening it. Hyaluronic Acid (heavy. Molecule)+ Collagen (Great Lakes brand). Exercise with focus on core muscles is a must. Remember, you cannot out exercise poor nutrition. My skin is looking like I’m in my 50yo years. Good luck.

    • @Mario-forall
      @Mario-forall Před 24 dny +4

      Resistance training and One Meal a Day should help reduce excess skin over a few years. The protein restriction should reduce the amount of skin produced while the resistance training reduces muscle loss. After all, you don't see any person with excess skin on concentration/refugee camps.

  • @richardgeddes630
    @richardgeddes630 Před 24 dny

    With all the solid, reliable knowledge that is currently cached, would it be possible to synthesize an ideal molecule or set of molecules to improve moisture, elasticity, and wrinkles or are researchers still in the dark about the mechanisms?

  • @Kingramze
    @Kingramze Před 24 dny

    It would be interesting to see how it compares with other antioxidants and supplements like glynac that lead to the production of more antioxidants, and also whether or not the combination has an additive effect or if the combo effect is no greater than one of them individually. Also if we'd start seeing negative effects from being too efficient at eliminating ROx

  • @anareginacoronado1147
    @anareginacoronado1147 Před 19 dny

    Do you think it could block vitamin d absorption or something?

  • @efx245precor3
    @efx245precor3 Před 23 dny +5

    But astaxanthin does a lot more for the body than just the skin

    • @Physionic
      @Physionic  Před 23 dny +2

      One investigation at a time :)

  • @KasKade7
    @KasKade7 Před 24 dny +4

    This stuff is so potent. You can eat it for sun protection.

  • @hitmusicworldwide
    @hitmusicworldwide Před 24 dny +1

    Keeping in mind that the body will prioritize essential internal health over outer health, I have assumed that the taking of suppliments that improve our health in these manners also aids in the integrity of the important endothelial structures internally. Aging internally is just as important as signs of aging and stress externally.

    • @Physionic
      @Physionic  Před 24 dny +2

      "Keeping in mind that the body will prioritize essential internal health over outer health," - I've never heard that before. I agree that aging internally is extremely important, though.

  • @vw3610
    @vw3610 Před 24 dny +7

    I noticed that when I took Astaxanthin, I never got sunburned

  • @earl9673
    @earl9673 Před 24 dny +5

    This channel makes me smarter than the average bear.

  • @adamscottv
    @adamscottv Před 24 dny +2

    Any opinion on astaxanthin vs curcumin?

    • @volos_olympus
      @volos_olympus Před 24 dny +1

      The former passed the ITP while the latter didn't.

  • @Duidee.
    @Duidee. Před 24 dny +2

    What do you think about astaxanthin as a 5-alpha reductase inhibitor?

    • @thomk3282
      @thomk3282 Před 24 dny +1

      Since dht is close to useless in adulthood the side effects of 5ar are linked to elevated levels of estrogen in some individuals, 2-4% of individuals according to studies. People with high aromatase activity and inadequate liver metabolism of estrogen (eat your broccoli)

  • @juliatshamoun4666
    @juliatshamoun4666 Před 24 dny +1

    ❤❤❤❤😊
    Which one is potent Astaxatine or Vitamin C?
    I take two capsules, Lutein +Astaxanthine daily makes up 50mg of Lutein and 10mg of the Astaxanthine❤

    • @ronrl7669
      @ronrl7669 Před 22 dny

      One is water soluble (Vitamin C), other is fat soluble (Astaxanthin) so they probably work in deferent environments. I take them both.
      Its important to not over dose them, specially in young age, cause over dosing antioxidants will eliminate oxygen species signal which is important to the body stress adaptation.
      So you need to balance them wisely. I, as a 45yo, usually use 100-200mg Vitamin C and not the overdose supplements that are selling around... and 6-12mg Astaxanthin.
      As you get older the body needs more antioxidants, But again need to do it slowly and wisely.

    • @franklinwaltz3978
      @franklinwaltz3978 Před 20 dny +1

      High dose lutein above 20mg per day can possibly cause crystalized glaucoma in the eyes. There have been cases.

  • @jp7357
    @jp7357 Před 24 dny +3

    I hope so, I take astaxanthin, zeoxanthin and lauthin … I hope 1 of 3 work for something

    • @user-ti9zc1xv2b
      @user-ti9zc1xv2b Před 23 dny

      Watch iut with Lauthin, high concentrations are found in parkinson brains

  • @Floating-Cows
    @Floating-Cows Před 24 dny +2

    Would this be synergistic with methylene blue?

    • @HellGod67
      @HellGod67 Před 18 dny

      All antioxidants do the same thing.

  • @DavidPaulNewtonScott
    @DavidPaulNewtonScott Před 24 dny +1

    I believe the ideal amount so far is 12mg per day see the Australian tv interview of the Japanese professors work. Unfortunately the suppliers seem to be all showing the amount in oil not the total astaxanthin content. An interesting point is lycopene seems to have similar effects and a few additional. So go for both. The lycopene is much easier to get. Tomatoes in a fatty meal. If you shove it in all your meals you end up with a sort of Turkish/Italian look to the food. Which is fine.

    • @pierrejeanes
      @pierrejeanes Před 23 dny

      you mean the content of astaxanthin is less or more??

    • @DavidPaulNewtonScott
      @DavidPaulNewtonScott Před 23 dny +1

      @pierrejeanes They fiddle you on the astaxanthin. I bought some on amazon 18mg it turned out to be 0.9mg in sunflower oil.

    • @pierrejeanes
      @pierrejeanes Před 20 dny +1

      @@DavidPaulNewtonScott you analyzed it or it was on the label? did it have some astaxanthin or only oil?, the fact that as I said in other comment I cannot get tanned now that I'm taking it , so I assume the prod6I bought may have some real deal..

    • @pierrejeanes
      @pierrejeanes Před 20 dny

      @@DavidPaulNewtonScott if you could share the brand name would appreciate it, thanks

  • @33Crazydude
    @33Crazydude Před 24 dny +4

    I'm taking Astaxathin, but I've become as little paranoid when taking it.
    For example, I hear that taking lots of antioxidants can blunt the post exercise adaption process 🤔
    Therefore, I'm only taking it on non training/gym days.
    Does anyone think I'm being silly in my approach 🤔 🤔

    • @rn5697
      @rn5697 Před 24 dny +3

      Just take it before workout
      Or at morning

    • @jakekinchen635
      @jakekinchen635 Před 24 dny

      my guess is, like most supplements, the effects build up over time, so it’s like only taking creatine on gym days. technically you could but it won’t be super effective. better to take it in longer periods where you’re not trying to induce hypertrophy. just my guess though.

    • @rn5697
      @rn5697 Před 24 dny

      @@jakekinchen635 IMO health is more important than building a little more muscle

    • @lewynld
      @lewynld Před 24 dny +3

      Most muscle synthesis occurs over a relatively long period. Many antioxidants are cleared quickly, like vitamin c. It only hangs around for 3-4 hours. Not sure about astaxthin, but taking it in the morning would likely be a good idea.

    • @badex3301
      @badex3301 Před 24 dny

      Nope, you’re not paranoid! I had same experience and had to get off it. It definitely nullifies the “good” inflammation you get post workout.

  • @isa-manuelaalbrecht2951
    @isa-manuelaalbrecht2951 Před 24 dny +1

    Here in CH it's merely recommended for eye problems with lutein...😁🤩😏

  • @sebastianell6259
    @sebastianell6259 Před 23 dny +1

    I dont get the mid point conclusion.
    "Astaxanthin has modest evidence in favor of it being an effective skin moisturizer, as well as improving skin elasticity" Arent these major points, when it comes to anti-wrinkling benefits? istnt you rconclusion contradictory then?

    • @alaaal-shakarchi8902
      @alaaal-shakarchi8902 Před 18 dny

      Thats what I thought. According to "science" it should be much more effective than Vit C for skincare

  • @janineclemons746
    @janineclemons746 Před 22 dny

    Your other studies analysis may cover this but I think topical analysis is usually unhelpful. Since aging is associated with inflammation I think that would be the better choice for analytical markers. Gut permeability might be a good indicator of collagen and elastin condition. Assessing a single nutrient is also likely deficient in producing a strong result.

  • @Tockin
    @Tockin Před 22 dny

    This is off topic but I was gonna ask: If someone is a healthy weight that exercises and has good muscle mass and they have no genetic predisposition to heart issues, do they still need to worry about what they eat as long as they stay at that healthy weight?

    • @KatSchlitz
      @KatSchlitz Před 22 dny

      Absolutely. Not a doctor here, but the body is a system of all interconnected parts and is handling genetic predispositions of all sorts (not just heart) as well as environmental pressures/ pollutants and also internal emotional stressors. Many things can break down early. Plus simple energy reserves and immune responses are far better with excellent living food intake. So absolutely yes.

    • @Tockin
      @Tockin Před 21 dnem

      @@KatSchlitz I was mainly asking in terms of the heart. I know there are plenty of reasons to always eat healthy, I just wanted to know if there could be heart issues to a fit person without genetic predisposition that eats junk.

  • @MademoisellleK
    @MademoisellleK Před 13 dny +1

    I take Nuchido, it makes my skin younger

    • @sunshinefl6586
      @sunshinefl6586 Před 6 dny +2

      ???

    • @lilacpeonies9643
      @lilacpeonies9643 Před 4 dny

      @@sunshinefl6586 I just looked it up… “In summary, Nuchido TIME+ appears to be a safe way to try to slow down ageing by reversing the decline in your NAD levels.”

    • @lilacpeonies9643
      @lilacpeonies9643 Před 4 dny +1

      I’m looking into this. I never heard of it either.

    • @MademoisellleK
      @MademoisellleK Před 4 dny

      @@sunshinefl6586 Nuchido is a supplement I take to increase my NAD+ levels

  • @buddymutt123
    @buddymutt123 Před 24 dny +11

    Science, Fuck Yeah!!!

  • @Viv8ldi
    @Viv8ldi Před 19 dny

    How is Astaxanthin compared to resveratrol and grape seed extract? Are they not all simialarly potent?

    • @HellGod67
      @HellGod67 Před 18 dny +1

      Forget about grape derivatives.

    • @man_at_the_end_of_time
      @man_at_the_end_of_time Před 13 dny

      Pine bark extract clearly helps with nitrous oxide, hint hint. Grape seed extract might help along those lines.

  • @Mario-forall
    @Mario-forall Před 24 dny +1

    Your CZcams Short are fine but nothing compares to these detailed analyses... I do miss the goofy jokes though 😅

  • @angfam7729
    @angfam7729 Před 24 dny +2

    You're funnier when you stand 🙂

  • @iangray5316
    @iangray5316 Před 24 dny +3

    I’ve heard people claiming that resistance training helps keep you looking young, unfortunately I’ve noticed quite the opposite. For the last two and a half years I’ve been training pretty hard and progressing but the downside of this is I’m noticing way more lines and wrinkles. Coincidence or perhaps a sign of something else going on?

    • @raraavis7782
      @raraavis7782 Před 24 dny +3

      Constant inflammation from beating up your body on a regular basis? Dunno. It's just a guess on my part, but I don't think it's a completely silly idea.
      Training very hard, very often *is* very stressful for the body.
      I did a mixture of CrossFit and weightlifting for 4+ years in my mid thirties and it really messed me up physically. 'Female issues', very high cortisol, bad sleep, a constant feeling of exhaustion. I had to completely stop that kind of training and it took a good year of only light exercise for me to recover. I do some strength training again now, but I don't beat myself up anymore.

    • @franklinwaltz3978
      @franklinwaltz3978 Před 24 dny +4

      Facial expressions from exercise especially weight lifting can cause wrinkles and fine line, I experienced this too.

    • @volos_olympus
      @volos_olympus Před 24 dny +6

      Your body fat content has dropped too low.

    • @boxtapper8550
      @boxtapper8550 Před 24 dny +3

      @@volos_olympus True , I went carnivore OMAD for a month , and lost a lot of weight. The loss of fat slimed my face down and suddenly wrinkles showed up. What they say is true , fat people don't have wrinkles.

    • @bahionic
      @bahionic Před 24 dny +2

      Could it be the dermal thickness, if you have some fine lines they might look deeper. So many factors play in, like your age, sun exposure, genes, diet.. and so on

  • @MikeG-js1jt
    @MikeG-js1jt Před 24 dny +1

    You looked like you were suffering some kind of gastric upset during the whole video.......... do you have agita?

  • @Holy.HannaH
    @Holy.HannaH Před 18 dny

    Seen this video pop up a couple days after I bought some astaxanthin & thought "I dont need to watch that"😂
    Now..I don't think I bought it for my skin but I cant recall.
    I did get some hyaluronic acid too though, so maybe?🤷‍♀️
    But I dont think so, it was probably for the antioxidant activity or something in my brain or eyes maybe.

    • @Physionic
      @Physionic  Před 18 dny +1

      HA is a great addition, Hannah.

    • @Holy.HannaH
      @Holy.HannaH Před 18 dny

      @@Physionic The HA & super high ppm hydrogen water(80-100ppm) are honestly the most incredible things I've ever put in my body and have provided the most benefit.
      I say that with nearly a hundred supplements in my arsenal that I no longer seem to need.
      (I order the 21.5ppm hydrogen tablets from Canada & add several to a single glass of water.)

  • @jpintero6330
    @jpintero6330 Před 24 dny

    Great video! I cut the pill and put it on my face. I look very crazy!

  • @artimizzia
    @artimizzia Před 24 dny +2

    2nd!📍

  • @jonathonmills3563
    @jonathonmills3563 Před 24 dny +6

    Given that extended lifespan in the mouse NIH ITP trial by 10%, we should be talking about that. Not wrinkles!

    • @Physionic
      @Physionic  Před 24 dny +4

      ITP is not in humans, but happy to cover it.

  • @TLW369
    @TLW369 Před 12 dny

    🥰

  • @Flapperjaw
    @Flapperjaw Před 22 dny

    Oh , did you say biased ? Well ,maybe you should discuss the bias of the pharmaceutical companies and the selective studies presented to their sibling , the FDA

  • @classicpinball9873
    @classicpinball9873 Před 24 dny +4

    First

  • @Hendrixski
    @Hendrixski Před 24 dny +4

    Is fighting wrinkles a medically relevant measure of skin health? My assumption is it's cosmetic and there are other better ways of checking skin health and skin functionality. I just don't know enough about it to ask the right questions.

    • @Physionic
      @Physionic  Před 24 dny +2

      Medically? Maybe not. I’d like that benefit, personally, but I also don’t limit my scope of interest to the medical relevance. Interesting question.

    • @jaycarver4886
      @jaycarver4886 Před 24 dny +5

      Since skin is our largest organ it only makes sense that what's going on with it is reflective of our internal state. Most people are living in a constant state of inflammation and aging is an external sign. While diet is of utmost importance there are obviously a lot of other factors at play. I took astaxanthin for a number of years when I was getting a lot of sun exposure and I think it served me well. Most of my family has had skin cancer but I have not. I eat a healthy, low carb/sugar diet, avoid toxins as much as possible and get adequate exercise so I'm sure that helps a lot with both skin and overall health. YMMV

    • @jcord0013
      @jcord0013 Před 24 dny +4

      Just because it helps skin does not mean that it is only cosmetic. Chances are, every organ, including brain, is benefiting from the antioxidant effect.

  • @greenstar3411
    @greenstar3411 Před 7 dny

    Dude at least do a summary
    I just wanted to know if it works better topical vs internally - I guess it’s somewhere in there… smh..

  • @modofatak
    @modofatak Před 24 dny +5

    P-Sonic…you seem STRESSED

  • @pierrejeanes
    @pierrejeanes Před 23 dny

    I think astaxanthin would be better if the person take enough macro and micro nutrients and exercise regularly, as well as sleep well, it will have more effect

  • @JerryWDaviscom
    @JerryWDaviscom Před 11 dny

    Get some rest, friend. It is obvious that you are nearly exhausted.

  • @eliziam3196
    @eliziam3196 Před 24 dny +1

    You look younger… 😮

    • @Physionic
      @Physionic  Před 24 dny +5

      I'm sure it's just the lighting - that, or my all cheese diet is paying off.

    • @jaycarver4886
      @jaycarver4886 Před 24 dny

      ​@@PhysionicIs it that constipated discomfort that people are commenting on?

    • @butch843
      @butch843 Před 24 dny

      😂​@@jaycarver4886

  • @astrol4b
    @astrol4b Před 24 dny +6

    I just want to be pink like a flamingo

  • @dianetheone4059
    @dianetheone4059 Před 21 dnem

    Totally-amateur-question:-is-a-placebo-group-equal-to-a-control-group-with-no-placebo,-or-is-best-practice-a-trial-group,-a-placebo-group,-AND-a-nothing-happening-here-control-group?
    Not-a-scientist🙃🙃🙃

  • @matttee1319
    @matttee1319 Před 24 dny +2

    Turd!... oops I mean third

  • @ainsleyameerali7622
    @ainsleyameerali7622 Před 18 dny

    Valasta astaxanthin is the bomb ......... excelente... those cheap astaxanthin that you see in walmart are a joke .... if you taking astaxanthin make sure it's Valasta..... full stop

  • @ronintage
    @ronintage Před 24 dny +1

    4th lol

  • @thomcarr7021
    @thomcarr7021 Před 24 dny

    At 7K views and 103 comments, three people claim it improved their eyesight. This would not indicate astaxanthin can improve eyesight but can have a serious side affect involving a persons imagination.

  • @nicholassteel5529
    @nicholassteel5529 Před 24 dny +2

    No! It caused ophthalmic migraines in me. Beware…..👍✌️

  • @xtmillsx
    @xtmillsx Před 24 dny +3

    Great information, however, I think you should re edit, and re narrate this, before release. You sound bored, impatient, and rushed.

    • @Physionic
      @Physionic  Před 24 dny +11

      Thanks for the feedback. Time is not a resource I possess, however. I was actually pretty excited to do this video, too - guess it didn’t carry over.

    • @ticketforlife2103
      @ticketforlife2103 Před 24 dny +18

      ​@Physionic not every comment holds meaning. Ignore it

    • @SapereAude1490
      @SapereAude1490 Před 24 dny +3

      ​@@PhysionicI find that playing the video at 1.25x speed removes this. But I am a chemist, so I can follow the terminology easily, so I could be biased.

    • @mballer
      @mballer Před 24 dny +2

      ​@@SapereAude1490
      I'm playing it at 1.5 and it sounds like a bit of breathing sinus problem, perhaps getting over a cold.
      But it doesn't affect the information.

    • @annettestevens2260
      @annettestevens2260 Před 24 dny +3

      geez I feel like his smooth bass voice is like esmr wouldn’t change a thing