Does retinol in skincare even work?

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  • čas přidán 6. 06. 2024
  • Does the best skincare ingredient even work? Some scientists and dermatologists say there's no trustworthy scientific evidence to back up retinol. Let's look at the evidence for retinol, and why skincare science might look a bit sketchy.
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    0:00 The case against retinol
    1:04 What is retinol?
    2:35 The dang government
    4:33 Why isn't retinol a drug?
    5:34 Cash Rules Everything Around Me
    10:24 The evidence for retinol
    15:11 What about other ingredients?
    How to start on retinoids: • How to Start on Retino...
    Ultimate vitamin C guide: • Ultimate Vitamin C Ski...
    My skincare eBook: labmuffin.com/skin
    Article with more info and full reference list: labmuffin.com/does-retinol-wo...
    🙋🏻 I'm Michelle, a chemistry PhD, cosmetic chemist and science educator, here to explain how beauty products work, debunk myths, and help you make smarter decisions about your skincare, hair and makeup!
    Blog labmuffin.com
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    📖 Key references
    www.mdedge.com/podcasts/derma...
    doi.org/10.1177/1740774515625964
    doi.org/10.1016/s0190-9622(98...
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  • Jak na to + styl

Komentáře • 904

  • @GlamorousGamine
    @GlamorousGamine Před 7 měsíci +1876

    Loved the statement that “only ingredients with robust clinical evidence work” is bad science. I’ll always remember the joke that there’ve been no peer reviewed clinical trials that parachutes decrease your risk of death while sky diving.

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +163

      Yes exactly! There's even an article in BMJ on it 😂 www.bmj.com/content/363/bmj.k5094

    • @mushy470
      @mushy470 Před 7 měsíci +15

      this was so funny loll@@LabMuffinBeautyScience

    • @arianathough2070
      @arianathough2070 Před 7 měsíci +70

      Yes! Not to mention the conflict of interest about the companies often being the ones who fund their studies in the first place

    • @AnUrbanGypsy
      @AnUrbanGypsy Před 7 měsíci +10

      @@arianathough2070We always have to follow the money.

    • @missknight9
      @missknight9 Před 7 měsíci +56

      “Parachute use did not reduce death or major traumatic injury when jumping from aircraft in the first randomized evaluation of this intervention. However, the trial was only able to enroll participants on small stationary aircraft on the ground, suggesting cautious extrapolation to high altitude jumps. When beliefs regarding the effectiveness of an intervention exist in the community, randomized trials might selectively enroll individuals with a lower perceived likelihood of benefit, thus diminishing the applicability of the results to clinical practice.” 😅👍

  • @DaniL-hr9xo
    @DaniL-hr9xo Před 7 měsíci +2011

    From a fellow scientist, it's so cool to see a video like this where you don't always talk about the main topic (retinol), but you also explain how scientific studies and publications work!! ❤🙏🏻

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +88

      Glad you liked it! I really enjoyed making it 😁

    • @mantolinez
      @mantolinez Před 7 měsíci +36

      As a a person who finished a PhD thesis im Materials science a few hours ago, I agree😊

    • @leptonsoup337
      @leptonsoup337 Před 7 měsíci

      Wow. I wish I had a phd fesis.@@mantolinez

    • @myselfme7945
      @myselfme7945 Před 7 měsíci +5

      As a student of social sciences I absolutely agree!

    • @adjaniaguilar
      @adjaniaguilar Před 6 měsíci +2

      Publish or perish 😅

  • @_oaktree_
    @_oaktree_ Před 7 měsíci +650

    Oh my god, as a librarian your section on how to search for and understand a study gave me life! I've taught these research methodologies and evaluation techniques to so many undergrads and it just gives me such pleasure to see this out in the wild, as it were :) And in the interest of helping consumers make scientifically-informed decisions!

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +50

      Librarians are unsung heroes! ❤

    • @jessss27
      @jessss27 Před 4 měsíci +9

      I'm excited at the prospect that skincare/beauty might spur young people learning how to research critically

  • @wallycola5653
    @wallycola5653 Před 7 měsíci +1013

    Well done! Simultaneously informative, funny, and unhinged. Person having a manic episode in front of a cork board is a really good look for you

    • @hannahshark8080
      @hannahshark8080 Před 7 měsíci +50

      I mean, she's not wrong on the subtle conspiracy aspect

    • @thousandsofstories
      @thousandsofstories Před 7 měsíci +54

      GUBERMINT was *chef's kiss*

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +196

      Thank you! I was worried I didn't look unhinged enough, my hair products were working too well on filming day 😅

    • @jenniferd264
      @jenniferd264 Před 6 měsíci +3

      @@thousandsofstoriesI spit my coffee laughing at that 😂😂❤

    • @betchbetchington6019
      @betchbetchington6019 Před 5 měsíci +1

      Facts.

  • @miriam8376
    @miriam8376 Před 7 měsíci +334

    I’m a rhetoric teacher and I ADORE seeing you address all the important elements in finding reliable research and how that is crucial to drawing sound, evidence-based conclusions. I’m going to show my students this video as an example of what ethical and reliable CZcams essays should aim for.

  • @Neiyk00
    @Neiyk00 Před 6 měsíci +420

    Retinol worked so well for me. My skin was a disaster before using it. Now, after 2 years I literally get compliments about my skin. However, it’s a long term solution and definitely requires consistency to work.

    • @tabithahamby4693
      @tabithahamby4693 Před 6 měsíci +5

      So cool to hear! What form/brand worked for you? 😊

    • @elenamiasnikova5574
      @elenamiasnikova5574 Před 6 měsíci +23

      Right, I use one of the probably cheapest solutions with low % of retinol and love the results. After I finish this one surely will buy something with higher %

    • @GodlessCog
      @GodlessCog Před 6 měsíci +44

      It was retinol and lactic acid for me. I am too young to tell whether or not it has prevented signs of aging but regardless of that, my skin is brighter and the texture is much smoother, and I hardly suffer significant breakouts anymore!
      It did also come with several lifestyle changes for me, though. Making sure I am hydrated, paying better attention to my diet, making sure I change my bedsheets more often, actually having a proper skincare routine where I previously did not have one... etc.

    • @youroverlordruler
      @youroverlordruler Před 5 měsíci +9

      ​@@GodlessCogI can swear by lactic acid lotion (using amlactin). I'm already getting great lightening results and still improving four months using. I had done a chemical peel gone slightly wrong on my underarms three years ago, which left it dark brown (ironically, I was trying to lighten my black underarms). But my skin was too sensitive. I started this year with niacinamide cream but it kinda stopped working two months in using. But lactic acid is still steadily lightening the area!

    • @tsuyuasui7297
      @tsuyuasui7297 Před 5 měsíci +1

      ​@@GodlessCog what type of lactic acid are you using?

  • @noa-ix9pe
    @noa-ix9pe Před 7 měsíci +395

    I never thought this much information could be crammed into my brain in such a short amount if time in such a fun way, mind blown, my bio teacher could never😶

    • @rubysresource
      @rubysresource Před 7 měsíci +13

      I play most educational videos, lectures, and podcasts at 3× speed, but Lab Muffin videos deliver information at an equivalent pace on 1× 🤣

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +56

      @rubysresource It's the ADHD 😂 Sometimes at my teaching job when a teacher is running behind, they get me to cover a lesson to help them catch up 😅

  • @who-is-eva
    @who-is-eva Před 7 měsíci +138

    As a baby dermatologist (just started my first job last month yay) and a skincare nerd (who used to have terrible acne), your channel is such a well of knowledge for me, i think i love you

    • @mthalter
      @mthalter Před 6 měsíci +26

      Baby dermatologist had me confused for a second lol 😂

    • @jenniferd264
      @jenniferd264 Před 6 měsíci +8

      Congratulations ❤😊 Best Wishes for a long and Happy Career!

    • @jenniferd264
      @jenniferd264 Před 6 měsíci +12

      @@mthalteromgosh….. it never occurred to me they could’ve meant Dermatologist for Infants 😂 till your post 😂😂😂 That’s Hilarious 😂😂❤

    • @PequenaNoobAmaPudim
      @PequenaNoobAmaPudim Před 6 měsíci +2

      ​@@jenniferd264i legit thought that was the case lmao

    • @chiccavaquita
      @chiccavaquita Před 6 měsíci +7

      @@mthalterI thought she meant she’s still in dermatology residency. A baby in her career 😂

  • @prismological
    @prismological Před 7 měsíci +125

    More Corkboard Michelle please. It’s fantastic energy

  • @khadinewarrick
    @khadinewarrick Před 7 měsíci +174

    This is the sort of content I hope for when some CZcamsrs preface their videos by saying they've done "research" into a certain topic, specifically those that tout their content as "educational". Really an excellent video! It was super informative while also being easy to follow and entertaining. Thank you! I learned a lot!

  • @blackrosenuk
    @blackrosenuk Před 7 měsíci +101

    We need more cork board Michelle!
    Seriously, thank you! You have a talent to make things educational, informative, interesting, and funny. Your smarts and hard work really shine in this video :)

  • @skinny0ne
    @skinny0ne Před 7 měsíci +8

    wow your studies/trials explanation was amazing. I’ve never heard anyone explain it this well and with passion!

  • @evan-vd4fu
    @evan-vd4fu Před 6 měsíci +12

    you are such a fantastic science communicator! such an underrated and important skill when research is constantly being twisted and misrepresented in media.

  • @pedrokass2973
    @pedrokass2973 Před 7 měsíci +107

    you deserve an award for your effort teaching science with common sense and creativity. Confession: I sent a message to youtube to tell them how extraordinary your videos are. Dr. Wong you're an excellent chemistry youtuber/teacher and not bad actress, brava! Claps in form of likes please.

  • @Sigurjon543
    @Sigurjon543 Před 6 měsíci +8

    Michelle your scientific communication skills are incredible and some of the best I’ve ever seen!

  • @gailkrumenacker2089
    @gailkrumenacker2089 Před 7 měsíci +168

    Excellent video!! So educational but still fun and not dry or too long! Wish more of my professors had been like you!

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +3

      Thank you! 😊

    • @BU272
      @BU272 Před 7 měsíci +5

      I'm a professor and also wish I was more like her!

    • @Merim.
      @Merim. Před 6 měsíci

      @@BU272
      ضًًة❤ص❤صضًضًًّّ❤❤❤صصككككككككككككككككككككككككككككككككككككككككككككككككككككككككص
      ص

    • @alexterieur8813
      @alexterieur8813 Před 4 měsíci

      @@BU272im sure you have your own qualities that she could learn from you!

  • @themaverickofbeauty
    @themaverickofbeauty Před 7 měsíci +12

    One of the best videos in the CZcams skincare game! I loved watching this and learning about the practicalities of research. Thank you!!!!

  • @farahdibasonda6708
    @farahdibasonda6708 Před 7 měsíci +30

    This video is pure GOLD! As expected from the queen! Looking forward to more videos like this on other ingredients. Lots of love 🥰

  • @jozefwoo8079
    @jozefwoo8079 Před 7 měsíci +16

    I've never been interested in cosmetics but this is such a thorough and interesting insight into it. I'm always delighted to be shown the hidden complexities behind a topic. This is the kind of quality most information should be! Congrats!

  • @markzeddo6033
    @markzeddo6033 Před 6 měsíci +32

    It was so great to get so much context about the usage of retinol: about the publishing ecosystem in both academia and industry, as well as how to interpret the studies that there are, even though there aren't clinical trials. Also, the use of the corkboard was perfect!

  • @agiles6483
    @agiles6483 Před 7 měsíci +7

    Girl, you rock! This was your best video, it was clear and the addition of humor was genius. I have wondered about the lack of well designed, double blinded skincare studies, especially on more than a handful of people. I knew it was about research funding, but I understand now that it’s more than just the money.

  • @sunmoon42
    @sunmoon42 Před 7 měsíci +103

    So much work went into this video! Both informative and fun

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +9

      I'm glad you enjoyed it! Yes it was a ridiculous amount of work but I think it was worth it, I felt like the topic deserved a thorough treatment.

  • @latifaayad3803
    @latifaayad3803 Před 4 měsíci +3

    Your board of crazy cracked me up---the messy hair, the smudged eyeliner---amazing. As academia-adjacent (creative writing PhD student) I LOVE hearing about how you've appraised the research. THANK YOU!

  • @fsantos199
    @fsantos199 Před 7 měsíci +6

    Your content is so so so amazing! Never get tired of watching your videos!

  • @CandeeseNotCandiss
    @CandeeseNotCandiss Před 7 měsíci +3

    You've done it again Doc - one of your best to-date!
    thanks for the time, effort, drawings and humour you put into edumucating us!

  • @whatreallyisart5898
    @whatreallyisart5898 Před 7 měsíci +3

    really good break down of why there isn't much high quality research into retinol and that things still can work without perfect evidence for it!! entertaining and informative

  • @LanaBana2931
    @LanaBana2931 Před 4 měsíci +1

    You’re my new favorite CZcamsr. Just discovered your channel, and now I must binge-watch all your content. You’re amazing! 🙌🏾

  • @Kilicka123
    @Kilicka123 Před 7 měsíci +2

    Yay! I was so hoping you'd cover the Sci VS. pod. This was a great video

  • @soozempen814
    @soozempen814 Před 7 měsíci +7

    Can't even imagine the amount of time and effort you put into this, so thank you!! My skin still isn't sure yet if it likes retinoids in any form, but this helps clarify (as much as it can!) why it seems some OTC products seem stronger/more effective than others. Much to think about.

  • @anaverran3040
    @anaverran3040 Před 7 měsíci +4

    So interesting and informative. Thank you for teaching us.

  • @shannoncult
    @shannoncult Před 7 měsíci +2

    This is the video I have been waiting for ever since listening to the Science Vs podcast episode on skin care. An absolutely brilliant explanation not just of retinol but of how science sciences.

  • @alansanjuliosutanto4240
    @alansanjuliosutanto4240 Před 7 měsíci +2

    Love this!! You could make a whole scientific article just to talk about this and publish it

  • @schibbolethsquad44
    @schibbolethsquad44 Před 7 měsíci +69

    Thank you so much for this video! It not only explains if, why and how retinol works but why and how science works. Clinical trials aren't the end all be all.

  • @MrThatGuyYouForgot
    @MrThatGuyYouForgot Před 7 měsíci +6

    Thank you so much for such informative videos!

  • @maziarjamshidi4505
    @maziarjamshidi4505 Před 4 měsíci +2

    This channel is what I've been looking for for so long... Accurate scientific facts instead of fancy doctors with paid products. Good job!

  • @terrigross1339
    @terrigross1339 Před 7 měsíci +2

    Thanks! This is so amazing to hear. You’re the only person I trust when it comes to skin care!

  • @kalindivictoria2771
    @kalindivictoria2771 Před 7 měsíci +14

    This video was awesome! As a psych student I loved the deep dive into research in the industry (or lack thereof)

  • @SchlichteToven
    @SchlichteToven Před 7 měsíci +100

    I think a lot of people think being skeptical or going against the mainstream automatically makes them scientific. It's cool to doubt. I listened to an episode of a podcast that was all about debunking everything, and the host interviewed a dermatologist who'd written a book on how retinoids basically do almost nothing (I had a lot of moments where I really wish I could have directly posed some questions to the dermatologist because she didn't seem to be taking everything into account), and at the end, the interviewer smugly asks the dermatologist if she personally uses retinoids, obviously expecting she'd say "hell no!" But the dermatologist said she does use them, because they work a little!

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +61

      I think that might be the podcast I referenced at the start 😅 Agree, there's a huge trend of edgy contrarian doctors at the moment ignoring all evidence beside clinical trial evidence, a few of the Science-Based Medicine writers have dubbed it "methodolatry" and it's a really interesting topic!

    • @SchlichteToven
      @SchlichteToven Před 7 měsíci +12

      @@LabMuffinBeautyScience Oh, it reminded me of that podcast, but I wasn't sure! That was the first and only episode I listened to because the interviewer seemed like she wanted retinoids to be a scam because certain other skincare ingredients have been shown to be ineffective, so that must be applicable to all popular skincare ingredients. Methodolatry's a good term for it! People seem to like stuff to be disproven more than to actually do the work to figure out what's true.

    • @Hhbb.9
      @Hhbb.9 Před 3 dny

      @@SchlichteTovenwhat is the podcast called?

  • @YukiSatagawa
    @YukiSatagawa Před 3 měsíci +1

    Michelle ur explanation and method to showing and presentation has improved over the years!! ☺️ It feels so easy to understand and know what’s going on around

  • @razielvalentine4076
    @razielvalentine4076 Před 6 měsíci +2

    What I like about you is that you’re not doing the typical “it works, trust me, bro” video. You actually encourage people to do their own research.
    Thank you!!

  • @happysponge0680
    @happysponge0680 Před 7 měsíci +11

    Loved this video! Especially the cork board 😂 can’t wait to see more about retinoids 👀

  • @catleaf
    @catleaf Před 7 měsíci +42

    this was such a good and refreshing video. the effort and passion you put into these really shows. thank you!

  • @JanineFalcon
    @JanineFalcon Před 6 měsíci +2

    I am only part way through this video and I’m enjoying it even more than I thought I would. Your creative and teaching skills are ⭐️⭐️⭐️⭐️⭐️

  • @devanshikotak4171
    @devanshikotak4171 Před 7 měsíci

    took me back to those chem classes oh my god MISSED THIS Michelle :( the way you communicate AMAZING.

  • @azharel
    @azharel Před 7 měsíci +7

    As a self-proclaimed student learning about skincare and having the benefits using Tretinoin your channel has been significant about getting what is useful and what is wasteful in skincare. Thanks!

  • @StephanieLeighG
    @StephanieLeighG Před 7 měsíci +83

    Since I know some people will only watch the first few minutes of the video and end up thinking she’s saying the exact opposite of what she’s actually saying, here’s the summary: 14:30

  • @ViktorDi
    @ViktorDi Před 7 měsíci +2

    Great video! I definitely learned some new things about the industry and retinol itself! Thank you for your work as always.

  • @dumatin
    @dumatin Před 7 měsíci +1

    This was an excellent video! So well explained. Thank you for all the work you put into this.

  • @pb_and_nutella
    @pb_and_nutella Před 7 měsíci +14

    Would love to see a video breaking down what you actually do and don’t need to do in terms of skincare, it feels like so much is a very expensive scam, and you’re kind of left to figure it out. Would love a “these are basics that do in fact work and everyone should do” and “these are the additional steps that can address specific common issues” video, for the skincare fed-up people of the world!

    • @EmyN
      @EmyN Před 7 měsíci

      She has an e-book I have seen

  • @amarug
    @amarug Před 7 měsíci +39

    Very interesting video, instant subscribe! My experience: I have been using Adapalene for over a year now daily before bed and I can say my skin looks so visibly different, it's evident without the need for scientific imaging for quantification and also discounting for some amount of "self-percention-distortion-via-placebo-effect". I never tried "typical cosmetic" Retinol, I went straight for the more druggy-variant. 😅

    • @manojipereira9169
      @manojipereira9169 Před 7 měsíci +3

      Yep I just started adapalene and had retinization, so I guess that's my sign that it's working

    • @d.on.in.a
      @d.on.in.a Před 6 měsíci

      ​@@manojipereira9169what is retinization?

    • @juliacastro8505
      @juliacastro8505 Před 6 měsíci

      yeah it took me a year, but my acne never came back

    • @user-bc5mz9bx5n
      @user-bc5mz9bx5n Před 4 měsíci

      I did too. Why would I pay so much money for something less effective?

  • @BakamonNO
    @BakamonNO Před 7 měsíci

    The work put into this video was awesome! Keep up the good work fam! 😄

  • @tomlangford4078
    @tomlangford4078 Před 7 měsíci

    This was excellent, would love to see a labmuffin update on innovations in skincare research

  • @lauraemilyaustria4116
    @lauraemilyaustria4116 Před 7 měsíci +5

    this was so funny and suuuperr informative!!! i appreciate your insight in breaking down the science for ppl (especially as someone that didn't do so hot in chemistry class!) + giving us the deal on the research and studies aspect (and the government!!) 10/10 on the production, the graphics are so nice to look at, too 😂looking forward to the next video ❤👌

  • @MovieTvDrama
    @MovieTvDrama Před 7 měsíci +4

    I spoiled myself when I scanned through the comments before getting to the evidence board segments, but I was still not prepared for the perfection that it is, communicating both the facts and the feeling. "That's not how companies think, they don't have skin." (6:48) encapsulates so much in this context and can be applicable in other circumstances as well.

  • @EH012
    @EH012 Před 7 měsíci +1

    What a little masterpiece of a video. SO GOOD.

  • @klosettchen
    @klosettchen Před 7 měsíci +2

    Amazing video! Loved the information combined with the comedy. You have helped me so much in the past to get a deeper understanding of academia and chemistry! ❤

  • @ky8519
    @ky8519 Před 7 měsíci +4

    Loved the crazy scientist vibe.you're my only trusted source of all things skin❤

  • @vicc19
    @vicc19 Před 7 měsíci +3

    Super interesting video, I've learned a lot, thank you! I didn't know, for example, that retinoids had two different categories. I, personally, prefer adapalene over retinol. I've tried both and adapalene had less side effects on me and provided the same results.

  • @taray8102
    @taray8102 Před 7 měsíci

    This is such an excellent video! Thank you for breaking the topic down.

  • @victoriaachkasova8534
    @victoriaachkasova8534 Před 6 měsíci +1

    This video is fantastic! High quality scientific communication 👏

  • @DancingThroughLifexoxo
    @DancingThroughLifexoxo Před 7 měsíci +4

    Definitely does, nothing else helped my acne for years until I started trying various retinol. I didn't love tretinoin from gp as my skin was so dry if I smiled I felt it split. But I got one for very dry skin from paula's choice and it's slower to work but is healing my skin so well

  • @risxra
    @risxra Před 6 měsíci +24

    Haven’t finished the video yet but the cutaway to the conspiracy board + “as a person who owns skin” sent me😂 Also love how thorough your explanations are of how clinical trials and studies work!

  • @juliabinford6500
    @juliabinford6500 Před 7 měsíci

    Loved the entertainment combined with accurate info about science!

  • @user-jv9xb5wz5c
    @user-jv9xb5wz5c Před 4 měsíci

    I am Impressed youre one of the few who actually Critisize Studies and not blindly use them.
    Thnak you so mich its a instant sub

  • @MsLinoi
    @MsLinoi Před 7 měsíci +5

    As someone in their 20s with acne prone skin, I believe that adapalene is superior to retinol. But that shouldn't be surprising☺️ I just wished it was available over the counter in the EU...
    It's difficult enough to find dermatologists without a long waiting list...

  • @Ima_meangirl
    @Ima_meangirl Před 6 měsíci +3

    I think it works. I use it and it makes my skin look great.

  • @angelinebiswas7611
    @angelinebiswas7611 Před 7 měsíci

    FANTASTIC EXPLANATIONS! Very well done!👍

  • @lindsay4111
    @lindsay4111 Před 7 měsíci

    Thank you for this video Michelle, I’ve always wondered about this topic ❤

  • @benjaminsamaha4687
    @benjaminsamaha4687 Před 7 měsíci +10

    It breaks my heart how few viewers you have 😭
    I want you to get that ad revenue so you can make more videos and I can put them on while I do chores and errands

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +3

      Thank you so much! The biggest bottleneck is the research part, the dream would be to hire someone to help with that... in the mean time, if you aren't already aware of it, I did 2 seasons of a podcast called Skincare School with Adore Beauty!

  • @froufroudeluxe
    @froufroudeluxe Před 7 měsíci +4

    This should be interesting!

  • @buddylove2073
    @buddylove2073 Před 4 měsíci +1

    Actually enjoyed your easy to follow and clear explanation about evidenced based research as well. I wish more lecturers took your approach.
    Wonderful!

  • @Queenofcats36
    @Queenofcats36 Před 6 měsíci +1

    Being a science nerd, I love this kind of thing. I enjoy learning the science behind why things work the way they do. This was super informative!

  • @db-gb5xi
    @db-gb5xi Před 7 měsíci +6

    Good timing. I just heard this come up recently in some comment sections. Most seem to say tretinoin is the only thing that works.

    • @lindsay6518
      @lindsay6518 Před 7 měsíci +3

      I SWEAR to god I used differen gel for YEARS to clear my cystic acne. It worked a treat, now I use a serum with bakuchiol and encapsulated retinol and it works the same as the differen gel did on my acne. It also gets rid of dark spots from sun damage.

    • @ghostratsarah
      @ghostratsarah Před 7 měsíci +2

      Weaker retinoids are great for young people to prevent weakening of the skin, and they are anti-microbial. Even cheap retinoids can prevent some acne and likely to prevent infections. Retinol is also now being used as an antibiotic alternative to treating MRSA/other resistant skin infections. As a MRSA carrier, I can confirm even lower end retinoid moisturizers can go a long way in treating mild infection and preventing infections altogether. You need moisturizer for skin infections, despite the common belief that you need to let them dry out.

  • @traepalmer
    @traepalmer Před 7 měsíci +36

    Great video. This echoes my experience with retinol, retinaldehyde, and tretinoin, as well: I've used all three, and they all produce the same result on my skin. Tretinoin just works a bit faster but is also more finicky to use in terms of dosing. And while any retinoid can make me ruddy-looking if I overuse it, tret can sometimes have this effect overnight from one use, so I still keep retinaldehyde on hand to swap in for tretinoin if I have an important event the next day and don't want to risk looking sunburned.

    • @MacielAnaLuiza
      @MacielAnaLuiza Před 7 měsíci +4

      Yes, I have the exactly same experience as you.
      Retinoids works really well for me. I can feel the difference in my skin (really quickly) when I stop using.

    • @nado5918
      @nado5918 Před 7 měsíci +11

      Wow, it’s good to know that all forms of retinoids provide the same results in the long term. I have sensitive skin so I can only tolerate retinol, but I’ve been feeling like I’m missing out for not using tretinoin. Your comment gives me the reassurance that retinol is just as good as long as I stay consistent.

    • @traepalmer
      @traepalmer Před 7 měsíci +1

      @@nado5918 there's variation between individuals due to enzyme polymorphism (thanks to @moskinlab for that terminology 😁), so my skin may just be unusually good at metabolizing retinol and retinaldehyde. I'm also only using retinoids for preventative antiaging and not to treat a medical condition or severe photodamage.
      But yes, on my skin, they all get to the same endpoint, the difference is just speed. I also have sensitive skin (DSNW in the Baumann system), and I think a lot of people who make pronouncements like "tret daily or bust" don't realize they have resistant skin and won't understand our skintype.
      Especially if you've tried tret and weren't able to tolerate it at any strength or frequency of application, I think it's fine to stick with nondrug retinoids like retinaldehyde or retinol. The alternative of leaving your skin in a perpetually irritated state just so you can say you're using tret isn't really sustainable long-term: you'll wind up with an even more impaired skin barrier which can paridoxically make your skin look worse or even "older" until it's healed.

    • @n.m.3995
      @n.m.3995 Před 4 měsíci +2

      I need Help. I use the inkey list retinol serum.
      It Hurts on my skin. Why?

    • @traepalmer
      @traepalmer Před 4 měsíci +1

      @@n.m.3995 you may be unusually sensitive to one of the retinoids in the product or to something in the vehicle. Have you experienced such a reaction with other retinoid products?

  • @andiej7163
    @andiej7163 Před 7 měsíci +2

    Thanks for another great video 😊

  • @skleroosis
    @skleroosis Před 7 měsíci +1

    What an excellent science communication video! Well done! (Also from a fellow scientist)

  • @lonelyboyxo
    @lonelyboyxo Před 6 měsíci +40

    I've been using retinol for almost 2 years now and my skin is FLAWLESS. Started at 23 (now 25) with Selfless by Hyram's retinol (0.2 + tranexamic acid + rainbow alge) for almost 1 year and half and now with Kiehl's retinol (0.3) x 3 times a week and i absooooooolutely don't regret it. Get yourself a Retinol, a moisturizer with Niacinamide and Ceramides to put on top, a Niacinamide, a Salicylic acid and a AHA serum for the rest of the week and BOOM! Bye-bye breakout, bye-bye lines, hello glass skin!

    • @birdlover7776
      @birdlover7776 Před 5 měsíci +1

      This sounds like a good regimen 👍

    • @betito5192
      @betito5192 Před 5 měsíci +7

      That sounds being 25🤷🏻‍♀️

    • @thehouseofnivara5710
      @thehouseofnivara5710 Před 5 měsíci +5

      ​@@betito5192 😂😂😂😂 come back to us after 10 years and kids

    • @y3sy3day
      @y3sy3day Před 5 měsíci

      genuinely dont know what you are talking about, are you trying to say that all young people have glass skin?@@betito5192

    • @margodphd
      @margodphd Před 3 měsíci +1

      Tbh when I was that age I could have used everclear and vaseline and I wouldn't have lines... because, you know,of the age 😅 That being said, starting sun protection and good habits early is super important... especially the sun protection part. A lot of skin condition is still genetic and metabolic, and perfect routine might still not give perfect results to people with different baseline. Enjoy the effects, just don't overdo it.

  • @sophiarose8127
    @sophiarose8127 Před 7 měsíci +10

    “….as someone who owns skin…” priceless!

  • @interruptivecow
    @interruptivecow Před 4 měsíci

    You are doing gods honest work explaining to lay people how to evaluate scientific papers

  • @Pattii248
    @Pattii248 Před 4 měsíci

    That is the content i love. Thank you so much for your effort!

  • @EmrysCorbin
    @EmrysCorbin Před 7 měsíci +4

    Skincare, science AND Tim Minchin clips in the same video? Yes please thank you.

  • @onionluigi6795
    @onionluigi6795 Před 7 měsíci +13

    Great video but I have one follow up question. While I dont doubt retinol works in (relatively) short term improvement of skin but shouldnt it by speeding up the cell cycle actually make skin age faster? I mean cells having more or less fixed number of times they can divide and all that. I was searching for some papers about this but didnt find anything except a few dermatologists saying "no its ok".
    If anyone got sth please comment link

    • @VitalyGG
      @VitalyGG Před 4 měsíci +4

      The Hayflick limit does not apply to skin cells because they are constantly being replenished by stem cells. A typical skin cell lives for about 27 days, but it is constantly being replaced by new cells from the stem cell population. This means that a typical human will go through many more than 50 layers of skin cells in their lifetime.

  • @Alice_Walker
    @Alice_Walker Před 7 měsíci

    This video is awesome. Thank you for your service to science and beauty and common sense in general 👑

  • @Shinobu553
    @Shinobu553 Před 5 měsíci +1

    Your videos are alwasy a pleasure to watch ⭐✨

  • @nova_beam
    @nova_beam Před 7 měsíci +9

    I’m really interested about learning more about retinol and how it works in this easy to understand format. I’m not a scientist or chemist so I really value information like this. I can’t wait for the retinol video and must go back and rewatch the other video about choosing one. Recently I’ve been using Naturim’s Retinaldehyde cream serum and wondered if their clams that retinal is a more broken down version of retinol that absorbs better into the skin is true. I hope I can learn the science behind things like this so I can make more informed choices.

    • @traepalmer
      @traepalmer Před 7 měsíci

      ​@@jehorigby8778prescription retinoids aren't universally cheaper: I pay $70 a tube for tret, and a lot of retinol and retinaldehyde formulas come in way under that.
      In fact, really the only way to get prescription retinoids much cheaper is to get them prescribed for a medical condition (e.g., acne) and to have health insurance that will cover that usage. Almost no private insurers will pay for retinoids prescribed for cosmetic use, and not all doctors are comfortable with falsifying a medical condition in a prescription in order to have it covered by a patient's insurance.
      There is also the option of importing them from overseas without a prescription, which risks safety issues with the product or confiscation by customs. They can also be purchased physically if one visits a country that sells them OTC (e.g., Mexico, some Southern European countries) in person, but there's still a risk, albeit minor, of them not being allowed past customs.
      Adapalene 0.1% is really the only drug retinoid that's on-par pricewise with nondrug retinoids like retinol and retinaldehyde, and it's now inexpensive because it's OTC, but it's only really been studied at the 0.3 % strength for antiaging, and that strength is still prescription-only, so would suffer the same pricing and access issues.
      So unless someone is using a particularly expensive retinol or retinaldehyde formula or has a doctor willing to write a prescription for a retinoid for a medical condition and this is covered by their insurance, getting a prescription retinoid is often going to be the more expensive choice.

    • @nova_beam
      @nova_beam Před 6 měsíci

      @@jehorigby8778 i understand a lot of the basics but I just want to know the difference between retinol and retinal. They appear to be similar, even in name, and I just wondered if one absorbed better than the other. The Naturium product was interesting to me because it uses retinaldehyde instead of retinol. Some “research” has suggested this is a better treatment than retinol. I don’t really consider the $30 dollar cream expensive, but a trip to a doctor to get something prescribed is definitely out of my price range.

  • @mushy470
    @mushy470 Před 7 měsíci +3

    9:18 btw this is what lisa eldridge did, she tested using her cleanser against nothing and then showed hydration levels. It could entirely be down to the water and not her cleanser and that is not mentioned but the "clinical trial results" are mentioned so many times in her marketing

  • @Koralgolster
    @Koralgolster Před 6 měsíci

    Thank you! I like both your videos and Science Vs. podcast and was a bit disappointed when I listened to that episode.
    I needed your video

  • @flexibezt
    @flexibezt Před 7 měsíci +1

    Love the creativity ❤❤❤

  • @wingedyera
    @wingedyera Před 7 měsíci +5

    I tried the special retinol eyecream from the Inkey list because I have hyperpigmentation and strange texture around my eyes. I tried it over a period of 4 to 6 months, skin was just constantly scabbing and dry. At first I thought this was fine, surely it meant my skin was renewing. But I figured that after a while my body would get used to it and adjust. It didnt. I just had dry scabby even more textured skin on my eyes that was still hyperpigmented. When I stopped the dry skin went away in a week. Retinols do seem to do something on my skin, but I wouldn't say its positive

    • @adminsucks8806
      @adminsucks8806 Před 6 měsíci +1

      Did u use moisturiser? Hydration? Hada labo works with retinol for me.

    • @wingedyera
      @wingedyera Před 6 měsíci

      @@adminsucks8806 I did, it just wasnt for me

    • @juliacastro8505
      @juliacastro8505 Před 6 měsíci

      you need to use moisturizer with retinol

  • @nolankvn
    @nolankvn Před 7 měsíci +59

    There was something on the skincare subreddits recently about the retinol in Paula's Choice and The Ordinary products being unstable or rapidly degrading. So, even if retinol does work, that's another thing I don't want to worry about. Also worth noting that prescription retinoids typically come in airtight metal tubes instead of airless pumps or dropper bottles.

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +55

      Yep, I'll be discussing those points and more in the next video! 😁

    • @roses00000
      @roses00000 Před 7 měsíci

      how dare they

    • @mona0monik
      @mona0monik Před 7 měsíci +2

      What's wrong with airless pumps?

    • @_oaktree_
      @_oaktree_ Před 7 měsíci

      I have a prescription retinoid in an pump bottle. www.aklief.com/content/images/product-packaging-desktop.jpg

    • @ninaxu541
      @ninaxu541 Před 7 měsíci +1

      can i see that reddit thread

  • @MRa-lh2nw
    @MRa-lh2nw Před 7 měsíci

    awesooome! waiting for part 2 ❤

  • @cindysmallwood2695
    @cindysmallwood2695 Před 7 měsíci

    Bravo!!! SO entertaining and SO informative! Love it

  • @JillKnapp
    @JillKnapp Před 7 měsíci +3

    Holy crap, Michelle, you're the freakin' best. Thank you for being so informative, but also so funny. I paused the video to see all the little easter eggs on the bulletin board. 😁

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +1

      Thank you! I'm so happy to hear you appreciate the easter eggs, I spent a lot of time on them hoping they'd be entertaining for someone apart from me 😂

  • @AliceintheRabbitHole
    @AliceintheRabbitHole Před 7 měsíci +4

    This is suuuch a well-done video!!
    I wish gubermint cared more about skin too 😖

  • @Liloldliz
    @Liloldliz Před 5 měsíci

    thanks for posting pure gold AGAIN

  • @maryp3212
    @maryp3212 Před 5 měsíci

    I taught high school science and spent countless lessons showing how to evaluate data in studies. Thank you for helping people see what’s behind the curtain.

  • @Dory_D
    @Dory_D Před 7 měsíci +29

    Thank you! 😀 Please also do a similar video about if vitamin C (and all it's 1 000 000 different forms) actually work.

    • @TosyaChan
      @TosyaChan Před 7 měsíci +3

      She's done it before

    • @LabMuffinBeautyScience
      @LabMuffinBeautyScience  Před 7 měsíci +22

      I did one on LAA but the one on derivatives is taking a while, partly because of the stuff I explained here - a lot of the data is supplier data and it's a mess to sort through! 😭 It'll happen

    • @Chewy635
      @Chewy635 Před 7 měsíci +1

      @@LabMuffinBeautyScienceI’m excited for this! I actually rewatched your LAA video a couple of weeks ago and looked for the followup on derivatives, and thought you’d maybe just moved on from it- I’m excited that it’s coming!

  • @xXNekou
    @xXNekou Před 7 měsíci +12

    I noticed some wrinkles on my forehead forming a couple of months ago and immediately I started using retinol serum every night on my forehead and I see a big improvement. So for me it works 🤗🤗

    • @SueRosalie
      @SueRosalie Před 7 měsíci +2

      you're likely just getting the benefits of moisturisation and paying attention to a regular routine

    • @xXNekou
      @xXNekou Před 7 měsíci +8

      @@SueRosalie nope, I always moisturized and had a routine before using retinol :) retinol serum is the only thing that changed and after using it for 6-7 months I see a difference

    • @raidexe
      @raidexe Před 6 měsíci

      I break out sometimes if I use too much, but it’s helping my forehead as well

  • @nostromofidanza1502
    @nostromofidanza1502 Před 7 měsíci

    Really great video. I'm a sucker for cosmetics being examined scientifically. Looking forward to the next video!

  • @Dante7652
    @Dante7652 Před 6 měsíci

    I love you endlessly for the meme plotting reference. Thank you. This was a great watch regardless and so informative.