Serotonin Syndrome vs. Neuroleptic Malignant Syndrome

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  • čas přidán 9. 03. 2019
  • ​​SUPPORT/JOIN THE CHANNEL: / @dirtymedicine
    My goal is to reduce educational disparities by making education FREE.
    These videos help you score extra points on medical school exams (USMLE, COMLEX, etc.)
    For educational purposes only; NOT medical or other advice.
    Some videos contain mild profanity and hyperbole solely used to assist with memorization. Viewer discretion advised.
    Opinions are entirely my own.

Komentáře • 114

  • @JustFe03
    @JustFe03 Před 3 lety +274

    Love your videos! Thanks for sharing. I use SS causes Sh*ts and Shakes

  • @DirtyMedicine
    @DirtyMedicine  Před 5 lety +31

    re-uploaded to remove background noise

  • @snussher
    @snussher Před 4 lety +46

    Great video, it really clicked when you said that the symptoms are just exaggerated forms of the side effects you get when starting those drugs normally! However, you can still get an elevated CK in serotonin syndrome. Probably the other thing to add is that NMS generally develops over days to weeks, and takes longer to resolve (slower onset, slow offset) whereas serotonin syndrome develops over 24 hours and resolves in 24 hours (quick onset, quick offset), but there is a bit of overlap

  • @ChloeDunIT
    @ChloeDunIT Před 5 lety +21

    Solid! This helps a lot! This is definitely the best CZcams channel for med students. Thanks as always man!

  • @carolinegladwell7855
    @carolinegladwell7855 Před 4 lety +10

    Watching this after my night shift and seeing a patient with NMS for the first time. Thank you for helping me understand x

  • @aftabahmad1682
    @aftabahmad1682 Před 2 lety +4

    A blessing for medical students. Thanks for providing high yield stuff and making usmle preparation very interesting.

  • @musicbeachdance
    @musicbeachdance Před 2 lety +4

    This video saved me so much time; I heard it 3x during class and still didn't fully understand it. However, now when i take my shelf exam i will visualize this 😊 thank you as always for your creative videos!

  • @tyrabanxx1514
    @tyrabanxx1514 Před 11 měsíci

    Wow!!! Just straight to the point and you made SO MUCH SENSE!! I needed this... thank you for being a great teacher!

  • @yanyanwang7094
    @yanyanwang7094 Před 3 lety +15

    😂dude with abs, you genius breakdown of the contents ! Thank you !

  • @fallenembers2518
    @fallenembers2518 Před 5 lety +5

    Sweet! Clear and concise man! Thank you for your insight! Keep it strong! #Fortheloveofmedicine

  • @yellowplasticsporks
    @yellowplasticsporks Před 3 lety +2

    This is brilliant. Thank you!

  • @aghosh2505
    @aghosh2505 Před rokem +1

    absolutely love it! just couldnt figure out how to differentiate these two!

  • @johangelymuro9609
    @johangelymuro9609 Před 2 lety

    Thanks for this video, I really needed it!

  • @agh6452
    @agh6452 Před 4 lety +1

    Thank you sooo very much for another best video 🙏🙏🙏🙏

  • @mumtazali2199
    @mumtazali2199 Před 2 lety +1

    Currently struggling to learn psych and your videos are so helpful an amazing!

  • @TylerBlah
    @TylerBlah Před 2 lety

    Why is this soooo good :) Thanks from Sydney Australia ! :D

  • @luciagratia
    @luciagratia Před 2 lety +1

    Aaaaah! Thank you so much! So helpful.

  • @C5A1
    @C5A1 Před 5 lety +16

    It is high-yield to add that the Tx for SS is cyproheptadine. Maybe you can think of someone dining on the top of the ship.

    • @C5A1
      @C5A1 Před 5 lety +5

      And the Tx for NMS is Dantrolene. Maybe think about that guy being named Dan, and he is so lean. (forrul tho he is shredded)

    • @DirtyMedicine
      @DirtyMedicine  Před 5 lety +15

      You can remember this for USMLE/COMLEX but in reality, I think it's worth mentioning that these are rarely used. A lot of med students get to the hospitals on rotation and embarrass themselves by saying it. These are pretty much last-line treatments if and when conservative measures fail.

  • @ashleytaylorfredrickson487

    😊Amazing Video I just walked away with way more Knowledge on this topic! THANKS FOR THE HELP! Your Videos are very much Appropriated!🤗

  • @andrenawright8037
    @andrenawright8037 Před 8 měsíci

    Really nice breakdown.

  • @term531
    @term531 Před 5 měsíci

    September 18, 2022 is my second birthday. My symptoms lasted for 20 hours, I passed out countless times, I was shaking UNCONTROLLABLE, I had diarrhea, my heart wanted to jump out, but at the same time I couldn't stand on my feet. When I was conscious I prayed to God to forgive my sins if this is the time for me to leave. After everything, they told me in the emergency room that it was a panic attack, countless infusions, because I was in two hospitals. I knew it wasn't because I was passing out all day. I was on anti-depressants and migraine medication, both of which have high doses of serotonin. I thank God for a second chance, and I am afraid of the incompetence of our doctors. 18.09. is the date of my patron saint and I know who saved my life then. Since then, I've been fighting and struggling with panic attacks, but that day was not one of them.

  • @isaacroberts9089
    @isaacroberts9089 Před 2 lety

    Hey this video is much better than a lot I watched earlier, much more accurate

  • @tahirjohar5775
    @tahirjohar5775 Před 4 lety +5

    I wish u were my teacher in med school . U are just pure class ❤❤❤

    • @geneveweil2938
      @geneveweil2938 Před 4 lety +2

      tahir johar then he would be limited to just one med school and inaccessible to us world over. I am so glad he is on here and helping med students world over

  • @atoyebikayode
    @atoyebikayode Před 11 měsíci

    Thank you so much for this information

  • @deargod5154
    @deargod5154 Před 2 lety

    So helpful!! Thanks

  • @MintyFarts
    @MintyFarts Před rokem

    Great way to break it down!

  • @nataliesimon852
    @nataliesimon852 Před 2 lety

    Thanks! really helpful

  • @cometaire1
    @cometaire1 Před 4 lety

    Excellent!!!!

  • @luminariamuscaria
    @luminariamuscaria Před měsícem

    sickkkk. thank you

  • @drmomnaghaffar9650
    @drmomnaghaffar9650 Před 10 měsíci

    Thanks!

  • @marie.s9995
    @marie.s9995 Před 5 měsíci

    Dirty!!! You saved me big time! Thank you!

  • @mamathastanly9718
    @mamathastanly9718 Před 2 lety

    Thank you sir, you are a good teacher

  • @phuongpupa4734
    @phuongpupa4734 Před 4 lety +1

    This helps a lot! Thank u very much!

  • @getxited
    @getxited Před 4 lety +1

    U R A GENIUS

  • @BaoNguyen-hb9ur
    @BaoNguyen-hb9ur Před 2 lety +1

    I wish I had you as a professor :)
    I would not fall asleep as much as I did

  • @zahrafrotan1727
    @zahrafrotan1727 Před 3 lety +2

    Lovely bro you saved me 🙏🌹

  • @cucumbermelon6166
    @cucumbermelon6166 Před 4 lety +23

    SS Tx = Cyproheptadine
    NMD Tx = Dantrolene

    • @DirtyMedicine
      @DirtyMedicine  Před 4 lety +22

      Yes but if they give you the option of a Benzodiazepine acutely, that will be the answer

    • @cucumbermelon6166
      @cucumbermelon6166 Před 4 lety

      @@DirtyMedicine Thank You!

    • @reemabdullah9877
      @reemabdullah9877 Před 3 lety +2

      @@DirtyMedicine i dont understand. Why would u give benzos.

    • @bikilatesfa5917
      @bikilatesfa5917 Před měsícem

      @@DirtyMedicine please do more psych videos, you are really amazing

  • @darrelllancaster9554
    @darrelllancaster9554 Před rokem

    Well done.

  • @hassan....6518
    @hassan....6518 Před 2 měsíci +2

    I suffered from serotonin syndrome after two weeks of taking Prozac, and then the doctor added another medication to me, which I took, and I had a panic attack, severe fear, and confusion, and I felt like I was going to die. I went to the emergency room in the hospital and met with another psychiatrist who had no experience. I told him, unfortunately, he told me that you have anxiety that is not from the medication, and he gave me another medication. So I believed his words and went into a coma due to serotonin poisoning. The medication was withdrawn from my body, but I suffered severe depression and anxiety after that because of this incident. I continued to suffer for years, and I am now fine, much better than before, and I am still recovering without antidepressant medication. When I went to a psychiatrist, he went because I have a phobia of... Providing lectures at the university only..I am very regretful and wrong for going to a psychiatrist. I lost 3 years of my life because of that.

  • @Dr.waleed-ur-Rahman
    @Dr.waleed-ur-Rahman Před 10 měsíci

    thanks DR

  • @Enpsychclopedia
    @Enpsychclopedia Před 3 lety +1

    Great explanation, very logical. I subbed. Why do you call it dirty medicine?

    • @roxana5490
      @roxana5490 Před 3 lety +1

      No idea, only thing I can think of is the "quick and dirty" phrase because his videos are concise and to the point.

  • @khaernyong5837
    @khaernyong5837 Před 3 lety +8

    I love the ABS haha! thank you!

  • @sadafhafeez7993
    @sadafhafeez7993 Před 2 lety

    Amazing!

  • @trans_diflu0r0ethane
    @trans_diflu0r0ethane Před 7 měsíci +1

    not a med student but nice vid! always wondered the exact dif between NMS and SS lol

  • @reasonableregret
    @reasonableregret Před 5 lety +13

    Holy shit look at the biceps 😂

  • @harshilkamdar4102
    @harshilkamdar4102 Před 4 lety +1

    Loved it

  • @MaisonNdukong
    @MaisonNdukong Před 5 lety

    Thank you so much ☺️

  • @jermainennaeto3479
    @jermainennaeto3479 Před 3 měsíci

    Best thing on the internet ever

  • @hotchocolatebrownie4397

    Tysm ❤️

  • @pumpkinspicekittens5758
    @pumpkinspicekittens5758 Před 3 lety +1

    I'm in love and this is the first video of yours I've seen

  • @Guyguyguy3030
    @Guyguyguy3030 Před 2 lety

    LOVE YOU!

  • @Maryah_an
    @Maryah_an Před 4 lety

    thank you a ton !

  • @mckamie6607
    @mckamie6607 Před rokem +1

    If it’s helps, NMS is “Neutrophil and Muscle Specific”

  • @olsonbryce777
    @olsonbryce777 Před 2 lety +1

    I've dealt with SS. the worst experience in my life.

  • @psychshell4644
    @psychshell4644 Před 2 lety +4

    I had SS twice. The ER docs didn't even seem to care. Thankfully, I knew what I had going on.

    • @micdan8000
      @micdan8000 Před 2 lety

      Did you get better? I have it

    • @psychshell4644
      @psychshell4644 Před 2 lety

      @@micdan8000 yes thank God

    • @micdan8000
      @micdan8000 Před 2 lety

      @@psychshell4644 that's good I'm glad

    • @VanessaGarcia-kg4wo
      @VanessaGarcia-kg4wo Před rokem +1

      How long did it take for you guys to go away. I have this rn and i think I might die

    • @kaneoneill106
      @kaneoneill106 Před 11 měsíci

      @@VanessaGarcia-kg4wo how has it been since, have you had any help or gotten any better??

  • @tomboynurse
    @tomboynurse Před 2 lety +1

    Hilarious illustration of a steaming boat & a white side for SS & NMS

  • @cillbobsy8236
    @cillbobsy8236 Před 3 lety +1

    Bonus to SS mneumonic… there is an origin story to the swear word for poo… Ship High in Transit (it is a weird origin, that is mostly debunked) but it used to be thought that ships with a lot of poo on deck would be referred to as this, and so it turned into a name for the swear word we all love.

  • @carriejohnson8299
    @carriejohnson8299 Před rokem +1

    SS...the letter S turned sideways looks like oscillations, which is also seen in clonus/hyperreflexia

  • @waizuv861
    @waizuv861 Před 2 lety

    "Look at these biceps... Holy**it they are rigid"

  • @hummtp
    @hummtp Před 5 měsíci

    LOL at the ABS, totally will stick with me

  • @mariamdaba
    @mariamdaba Před 4 lety

    Love this!

  • @empyie666
    @empyie666 Před 2 měsíci

    The ABS mnemonic is so funny LMAO

  • @HT.100
    @HT.100 Před 5 lety +2

    why did you take down the vitamin video?

    • @DirtyMedicine
      @DirtyMedicine  Před 5 lety +9

      re-uploading the last 3 videos to remove background noise in the audio. Will be back up shortly

    • @HT.100
      @HT.100 Před 5 lety

      thank you so much for making these. much appreciated

  • @kayallen7603
    @kayallen7603 Před 5 měsíci

    on wrong meds: (anti-depressants) = SS ; (anti-psychotics) = NMS

  • @AyeshaKhan-nt6hh
    @AyeshaKhan-nt6hh Před 3 lety

    "holy shit they are ridged"

  • @legionnairestentorian1853

    My book also says NMS also has diarrhea

  • @phuongpupa4734
    @phuongpupa4734 Před 4 lety

    HN 28/3/2020 in quanrantine state

  • @samijami7167
    @samijami7167 Před 4 lety +3

    u deserve a kiss thank you

  • @ThatsWhy-
    @ThatsWhy- Před rokem

    In SS , Ca+⬇️ but in NMS , Ca+⬆️

  • @shuhshuhshane
    @shuhshuhshane Před rokem

    Trying to get those abs tho

  • @drdeivanai8946
    @drdeivanai8946 Před 4 lety

    Bless u dirtyusmle

  • @beautyunknown8062
    @beautyunknown8062 Před 3 lety

    What’s the difference between the two packages $5 vs $15?

  • @robnation2475
    @robnation2475 Před 3 lety

    He's got really sick abs

  • @sarahmiles2665
    @sarahmiles2665 Před 4 lety +1

    excellent visuals, now i will NEVER forget the difference hahahah

  • @JohnnyGarman
    @JohnnyGarman Před rokem

    Admin reveal @8:00

  • @adriancoleman2876
    @adriancoleman2876 Před 3 lety

    hot guys on boats, finally pharmacology makes sense.

  • @_fayou_
    @_fayou_ Před rokem

    🤗💪

  • @anniegoldie
    @anniegoldie Před 2 lety +3

    Hey man, love your videos, but there is a significant error. Severe serotonin syndrome can definitely cause rigidity and elevated CK, just like NMS. A much better way to distinguish the two is that the onset of serotonin syndrome is much more acute (starts within a day of starting the culprit medication with maximal symptoms within hours of onset) than NMS (which can take days to weeks to months to start, and can take several days to maximal symptoms).

    • @DirtyMedicine
      @DirtyMedicine  Před 2 lety +3

      I get what you're saying, but when thinking about SS vs NMS **for the purposes of exams**, its not useful to think of rigidity in SS because the test writer wouldn't confuse you with that, and instead would use more commonly defined buzzwords for each.

    • @anniegoldie
      @anniegoldie Před 2 lety +2

      @@DirtyMedicine Are you saying that it's more important to teach/learn buzzwords in order to get an exam question right than it is to actually learn medicine?
      USMLE question writers are more savvy that you are giving them credit for.
      (EDIT: "savvy" as in not relying on classic buzzwords when they reinforce false ideas about disease presentations)

  • @imagesbydavide
    @imagesbydavide Před 3 lety

    great explanatory video,
    bit of cocky attitude tho

  • @avsoni97
    @avsoni97 Před 2 lety +2

    Good explanation worst mnemonic

  • @kyotog777
    @kyotog777 Před 3 lety +1

    Don't take poppy seed tea with st. John's Wort, worst mistake of my life

  • @lesterleland
    @lesterleland Před 2 měsíci

    tREATMENT, NO CURES= CHA-CHING

  • @nursejaymee
    @nursejaymee Před 3 lety

    holy shit they are rigid ... haha

  • @FriedEgg101
    @FriedEgg101 Před 4 lety

    I have the best shits on lsd. No diarrhoea, just the ability to completely evacuate my colon. I suffer from migraines that only end after a good shit, so lsd is a good way to abort a migraine.

  • @1412Z
    @1412Z Před 10 měsíci

    Thanks!