Effect of catecholamines on systolic and diastolic blood pressure

Catecholamines act as sympathomimetics but still produce different action on systolic blood pressure (SBP) and diastolic blood pressure (DBP). The effect produced on these blood pressures depends on the type of catecholamine and its relative selectivity towards alpha and beta receptors. Norepinephrine is more selective towards alpha receptors show a pronounced effect on SBP while isoproterenol is more selective towards beta receptors and thereby produces marked effect on DBP. On the other hand, dopamine is also acts on dopamine receptors in addition to its action on alpha and beta receptors. Due to its action on dopamine receptors, it produces renal vasodilatation and a fall in DBP.
#systolic
#diastolic
#bloodpressure

[@Covertlybound]

Thank you sir for this good explanation.

[@ephrata8402]

Thank you so much, so clarifying

[@madmedicos3759]

Thank you so much sir for the crystal clear explanation 😊

[@egpat]

You are most welcome

[@avanthikasuriyanarayanan1384]

Thank you so much sir for this wonderful explanation . My cardio exam is in a few days and these videos are just the best for a quick recap of the concepts.

[@egpat]

Glad it was helpful! All the best

[@nareshkumar.v6207]

Thank you sir

[@riteshchaurasia4953]

Great lecture sir..

[@riteshchaurasia4953]

How diastolic bp and tpr interrelated..and what are the factors affecting it..

[@surajad8114]

Amazing🎀💕💛

[@riteshchaurasia4953]

Sir what are the factors affecting diastolic bp and what are the receptors regulating it..

[@riteshchaurasia4953]

Since dopamine receptor are present in kidney how does it affect tpr..

[@riteshchaurasia4953]

Sir if u could explain why epinephrine decreases diastolic and tpr..since both alpha and b receptor are present..

[@odisiusX5]

Because it has selectivity for both Beta and Alpha. It activates equally both receptors, thus, it results In vasoconstriction through alpha (i.e, increased SBP) and vasodilation through Beta to the heart and skeletal muscle and liver (i.e, a slight decrease in DBP and TPR).

[@riteshchaurasia4953]

Why does epinephrine causes decrease diastolic bp through b receptor why not through a1 receptor causing increase in diastolic bp..and same question for systolic bp why not b causes decrease in systolic and why not a causes increase in tpr. .

[@shafiquekhan70]

Gd

[@marcelas7064]

🇮🇳